I-6-paradol iyinhlanganisela etholakala ku-ginger. Kuyinhlanganisela eyenzeka ngokwemvelo ekhonjiswe ukuthi inezinzuzo zezempilo ezingaba khona. Lokhu okuthunyelwe kuzofaka konke odinga ukukwazi mayelana ne-6-paradol nokuthi ingazuzisa kanjani impilo yakho.
- I-6-paradol iyisakhi esisebenzayo sembewu ye-Guinea pepper (Aframomum melegueta noma izinhlamvu zepharadesi). Isuselwa ekilasini lamakhemikhali aziwa ngokuthi ama-alkylphenols, okuyizinhlanganisela zemvelo. I-6-paradol, evame ukwakhiwa kusuka ku-6-gingerol nge-6-gingerenol, iyingxenye encane yejinja, futhi njenge-phenol evuselelayo etholakala emndenini we-ginger, itholakala ezitshalweni eziningi, kuhlanganise ujinja, upelepele omnyama kanye nesesame, futhi izinhlobonhlobo zemisebenzi yebhayoloji. Le nhlanganisela ye-bioactive iwumthombo we-flavour ehlukile yejinja futhi iboniswe inezinzuzo eziningi zezempilo. Uma i-6-Paradol ibophezela endaweni esebenzayo ye-cyclooxygenase (COX-2), ivimbela ngempumelelo ukukhula kwesimila kumagundane anomdlavuza wesikhumba. I-6-Paradol futhi inezinzuzo eziningi zezempilo ezifana ne-anti-inflammatory, antioxidant, anti-obesity, ukwehlisa umfutho wegazi kanye nokwenza ngcono inkumbulo.
Umthelela we-6-paradol ekuthathweni kweglucose waphenywa ku-C2C12 myotubes (amaseli emisipha) kanye ne-3T3-L1 adipocytes (ama-fat cells). Imiphumela yabonisa ukuthi i-6-paradol ayigcini nje ngokukhulisa ukutholwa kwe-glucose kuwo womabili amaseli, kodwa futhi yathuthukisa umsebenzi wamaprotheni athile ukuze kukhuthazwe ukutholwa kwe-glucose. Izindlela eziqondile lapho i-6-paradol ikhuthaza ukusetshenziswa kwe-glucose nazo zabonakala. Okokuqala, i-6-paradol ithuthukise ukusebenza kwephrotheni ebizwa ngokuthi i-AMPK. Le phrotheni inesibopho sokulawula amandla e-metabolism kumaseli, futhi ngokwenza i-AMPK isebenze, i-6-paradol inyusa ukumuncwa kweglucose ngamaselula. Ucwaningo oluhlobene lukhombe i-6-paradol njengendlela yokwelapha engaba khona ekwelapheni isifo sikashukela nokukhuluphala.
Ngakho-ke, i-6-paradol, njengenhlanganisela yemvelo, ingasetshenziswa kuzo zonke lezo zindawo!
(1) Isetshenziswa njengesengezo sokudla
I-6-Paradol iyi-ketone enephunga elimnandi ewumthombo we-Grains of Paradise ukunambitheka nephunga eliyingqayizivele. Sekungamakhulu eminyaka isetshenziswa emithini yendabuko futhi ingasetshenziswa njengesinongo ekuphekeni nanjenge-ejenti yokunambitheka eziphuzweni. Itholakala ku-ginger, upelepele omnyama kanye nembewu yesesame, futhi iphinde ibe yi-sub-organism ye-ginger, bese ingasetshenziswa njengesengezo sokudla, isengezo esiphelele ohlwini lwezinongo ezingasiza ukwenza ukudla kube mnandi futhi kube mnandi. . Yiqiniso, ingafakwa hhayi kuphela ekudleni, kodwa naseziphuzweni. Uma kuqhathaniswa nezinye izithasiselo ezinoshukela emakethe, i-6-parado ingokwemvelo, ngakho uyisinqumo esingcono kakhulu sokwengeza ubungqabavu kanye nobumnandi ekudleni naseziphuzweni.
(2) Kungasiza ukuthuthukisa ukugaya
Empilweni, abantu abaningi bahlushwa ukuqunjelwa kanye nokungakhululeki kwesisu, ngakho-ke ungase ucabangele i-6-Paradol, omunye wemiphumela yayo ukusiza ukudiliza nokugaya ukudla esiswini, futhi uma kuthathwa ndawonye njengesengezo sokudla kunganciphisa ezinye izinkinga zokugaya ukudla, kodwa-ke lezi zinkinga azikona nje ukuqunjelwa kanye nokuvuvukala njengoba kushiwo esihlokweni, ngoba i-6-Paradol inezindawo zokulwa nokuvuvukala, ezingasiza ekunciphiseni ukuvuvukala emzimbeni, okungaholela ekuzuzeni isisindo nezinye izinkinga zempilo, kuhlanganise nokuqunjelwa kanye nokuvuvukala. isicanucanu.
(3) Amandla okuthuthukisa ukuqonda
Enye inzuzo ye-6-paradol, amandla ayo okuthuthukisa ukusebenza kwengqondo. Ucwaningo lubonise ukuthi i-6-Paradol ingasiza ukuthuthukisa inkumbulo nokunaka futhi ivimbele ukwehla kwengqondo okuhlobene neminyaka. I-6-Paradol isiza nokuvikela amangqamuzana obuchopho ekuvuvukeni kanye nama-antioxidants. Lokhu kusiza ukuthuthukisa impilo nokusebenza kwesikhathi eside. Isithako sayo esisebenzayo, i-6-gingerol, nayo ikhonjiswe ukuthi ikhuthaza impilo yesistimu yezinzwa.
Ucwaningo lwesayensi lubonise ukuthi i-6-Paradol inemiphumela eminingi emihle emzimbeni. Le miphumela ihlanganisa:
(1) Ukuqeda ukuvuvukala
I-6-Paradol inezinto ezinamandla zokulwa nokuvuvukala ezisebenza ngempumelelo ekwelapheni ukuvuvukala emzimbeni. Ucwaningo luye lwabonisa ukuthi lungavimbela ukukhiqizwa kwama-cytokines ane-pro-inflammatory, anesibopho sokuthuthukiswa kokuvuvukala okungapheli.
(2) Imiphumela yokulwa nomdlavuza
Ngokwezifundo, i-6-Paradol ingavimbela ukukhula kwamangqamuzana omdlavuza emzimbeni. Le nhlanganisela isebenza ngokwenza i-apoptosis, inqubo eholela ekufeni kwamangqamuzana omdlavuza.
(3) Umphumela we-Neuroprotective
I-Neuroprotection isiza ukuvikela isimiso sezinzwa somuntu ekulimaleni noma ekulimaleni okungase kubangelwe izimo zezempilo ezinemiphumela emibi yemizwa. I-6-Paradol inezakhiwo ze-neuroprotective ezisiza ukuvimbela ukulimala okuqhubekayo kwezinzwa futhi kubambezele ukuwohloka kwesimiso sezinzwa esiyinhloko, esingavimbela izifo zemizwa ezifana nesifo i-Alzheimer's.
(4) Umphumela we-Antioxidant
I-6-Paradol inezinto ezinamandla zokulwa ne-antioxidant ezisiza ukunciphisa ukulimala kwe-oxidative emzimbeni. Le nhlanganisela ye-bioactive ingavimbela izifo nezimo ezihlukahlukene.
Kungakhathaliseki ukuthi ubani, kubonakala sengathi ayikho enye indlela yokunciphisa umzimba ngaphandle kokuzivocavoca nokuzilolonga. Ngokusekelwe kulo mbono, uma ufuna ukwehlisa isisindo, udinga ukulawula ngokuqinile inani lamakholori owadlayo futhi uphinde uzivocavoce ukuze unciphise inani lamakholori angadingekile, kodwa imiphumela ingase ingabonakali kangako. Ucwaningo luye lwabonisa ukuthi enye yezinzuzo eziyinhloko ze-6-Paradol yikhono layo lokusiza ukunciphisa isisindo, nokuthi i-6-Paradol ingasiza ekunciphiseni isisindo ngokwandisa izindleko zamandla emzimbeni. Ngokusho kocwaningo, le nhlanganisela ye-bioactive ingakhuphula izinga lokushisa lomzimba futhi isheshise imetabolism, okungaholela ekulahlekelweni kwamafutha. Le nqubo ingasiza ekuthuthukiseni i-metabolism futhi ishise amakholori amaningi, ngisho nalapho uphumule. Lokhu kusho ukuthi ngokusetshenziswa kwayo, akudingeki ukhathazeke ngokuzivocavoca nokudla. Ungakwazi ukuqaphela kancane ukuthi udlani nokuthi ujima kangakanani, kodwa nokho ukwandisa imiphumela yakho yokulahlekelwa isisindo.
Umzimba ugcina amafutha omzimba ngemibala nezinhlobo ezimbili, amafutha amhlophe namafutha ansundu. Amafutha amhlophe, aziwa nangokuthi amafutha e-visceral, akhiwe ngamaconsi e-lipid kanye nomugqa omncane ohlanganisa i-nucleus ne-cytoplasm. Iqoqana ikakhulukazi eduze kwesisu sethu; kuyilapho amafutha ansundu, aziwa nangokuthi i-BAT eyenziwe, esebenza ukulawula izinga lokushisa lomzimba lapho kubanda.
Kukhona izifundo ezifanele ezibonisa ukuthi i-6-paradol iguqula izicubu ze-adipose ezimhlophe zibe izicubu ze-adipose ensundu, ngaleyo ndlela enze amafutha agciniwe ayisicefe atholakale kalula ukuze athole amandla. Ngaphezu kwalokho, izicubu ze-adipose ezinsundu zisebenzisa ushukela wegazi kanye ne-lipids, ngaleyo ndlela zithuthukise i-glucose metabolism namazinga e-lipid. Ngakho-ke, uma unezicubu ze-adipose ezinsundu kakhulu, amafutha amaningi omzimba azosetshenziswa njengamandla, ngaleyo ndlela andise izindleko zakho zansuku zonke zamandla.
Isiphetho
Sengiphetha, i-6-paradol iyinhlanganisela enamandla etholakala ku-ginger. Kuye kwaboniswa ukuthi kune-anti-inflammatory, anti-cancer, anti-obesity, antidiabetic, ne-neuroprotective properties. Kubhekwa njengokuphephile ukudliwa. Indlela engcono kakhulu yokuthola i-6-paradol ukuthatha isengezo. Nokho, ngaphambi kokuthatha noma yisiphi isengezo, kubalulekile ukukhuluma nodokotela wakho.
Isikhathi sokuthumela: Jun-07-2023
