I-Calcium Alpha Ketoglutarate iyinhlanganisela enamandla okulwa nenqubo yokuguga. Indima yayo ekuthuthukiseni impilo ye-mitochondrial, ukuhlinzeka ngama-antioxidants, kanye nokuthuthukisa ukukhiqizwa kwe-collagen kwenza kube inketho ethakazelisayo kulabo abafuna ukugcina ukubukeka kobusha. Njengoba ucwaningo luqhubeka, maduze nje singase sembule izinzuzo ezengeziwe ze-CAKG.
I-Calcium Alpha-Ketoglutarate iyinhlanganisela enamandla eyaziwa nangokuthi i-AKG Calcium ehlanganisa i-Calcium ne-Alpha-Ketoglutarate edlala indima ebalulekile ezinqubweni eziningi zezinto eziphilayo Umjikelezo we-Krebs ungowethu Inqubo umzimba okhiqiza ngayo amandla, i-alpha-ketoglutarate iyingxenye ebalulekile ye umjikelezo we-Krebs. I-calcium alpha-ketoglutarate ikhiqizwa lapho amaseli emzimbeni wethu ephula ukudla ukuze athole amandla.
I-calcium alpha-ketoglutarate nayo idlala indima ekukhulumeni kofuzo njengendlela yokulawula evimbela amaphutha okubhalwa kwe-DNA avame ukuholela ezifweni ezinjengomdlavuza.
Nakuba iCalcium Alpha-Ketoglutarate ikhiqizwa umzimba womuntu, asikwazi ukuyithola ngokuqondile ngokudla. Singayigcina ngokuzila ukudla kanye nokudla kwe-ketogenic, kodwa njengoba ucwaningo oluqhubekayo luye lwathola ukuthi ngokufaka i-Calcium Alpha-Ketoglutarate supplements ukuze kwandiswe.
Izinzuzo zezempilo ezingaba khona ze-calcium Calcium Alpha-Ketoglutarate:
●I-Anti-Aging/Life Extension
●Thuthukisa impilo yamathambo futhi uvimbele i-osteoporosis
●khipha ubuthi emzimbeni
●Thuthukisa ukusebenza kwamasosha omzimba
●Thuthukisa i-metabolism
●Gcina impilo yenhliziyo nemithambo yegazi
1. Izinsiza ekunqandeni ukuguga/engeza isikhathi sokuphila
Ezifundweni ezihlobene, i-Calcium Alpha-Ketoglutarate (CaAKG) ifakazelwe ukuthi ilwa nokuguga futhi yelula impilo ngezinga elithile.
Njengoba sikhula, amangqamuzana ethu aba nezinguquko ezihlukahlukene zomzimba eziholela ezimpawu ezibonakalayo zokuguga. Ngokugcwalisa imizimba yethu nge-CaAKG, sinamandla okunciphisa le nqubo.Ngokuqondile, ukuvinjelwa kwe-mTOR kubonakala kukhuthaza ukuphila isikhathi eside kwamaseli futhi kunciphise ingozi yezifo ezihlobene nobudala ngokwandisa i-autophagy.
Ucwaningo lukhombisa ukuthi ukwesekwa kwe-CaAKG kusiza ukugcina impilo ye-mitochondrial, ethuthukisa ukusebenza kwamaselula. I-Mitochondria yimithombo yamandla yamaseli ethu anesibopho sokukhiqiza amandla, futhi lapho esebenza kahle, ukuguga kwamaselula kuyabambezeleka.
2. Thuthukisa impilo yamathambo futhi uvimbele ukukhumuzeka kwamathambo
Kubantu abaningi, ngenxa yokwanda okuqhubekayo kweminyaka yobudala, amathambo azoba buthakathaka kakhulu futhi kulula ukuphuka. I-calcium iyingxenye enkulu yamathambo futhi i-alpha-ketoglutarate ikhonjisiwe ukwanda (ukwakheka kwamaprotheni futhi kuthuthukise ukwakheka kwezicubu zamathambo). Faka isandla ekumunceni nasekusetshenzisweni komzimba. Ngokwandisa amazinga e-calcium, i-Ca-AKG isiza ukuvimbela izifo ezifana ne-osteoporosis kanye ne-osteopenia, ezibaluleke kakhulu kokubili kwabancane nabadala.
3. Khipha ubuthi emzimbeni
Enye inzuzo yezempilo ephawulekayo ye-calcium alpha-ketoglutarate indima yayo ekukhishweni kwesibindi. Isibindi siyisitho esiyinhloko sokususa ubuthi emzimbeni wethu, futhi i-alpha-ketoglutarate isiza ukuthuthukisa ikhono layo lokususa ubuthi. Ngokugqugquzela ukukhiqizwa kwe-glutathione, i-antioxidant enamandla, i-Ca-AKG isiza ukuqeda ubuthi obuyingozi futhi ivikele impilo yesibindi.
4. Khulisa ukusebenza kwamasosha omzimba
Ukugcina amasosha omzimba aqinile kubalulekile ukuze kuvikelwe amagciwane ayingozi nezifo. I-calcium alpha-ketoglutarate idlala indima ebalulekile ekuqinisekiseni ukusebenza kahle kwamasosha omzimba. Isekela ukukhiqizwa nokusebenza kwamangqamuzana omzimba omzimba, ithuthukise izindlela zokuzivikela.
5. Ukuthuthukisa umzimba
I-Alpha-ketoglutarate idlala indima ebalulekile ekulawuleni nasekugcineni i-metabolism enempilo. Ngokukhethekile, izinga amangqamuzana akhipha ngalo amandla kuma-molecule okudla lincike emazingeni e-alpha-ketoglutarate akhona. I-Alpha-ketoglutarate ibandakanyeka kumjikelezo we-tricarboxylic acid (umjikelezo we-TCA), inqubo eyinhloko yokukhiqizwa kwamandla kumaseli. Kuyasiza ukunikeza amandla amangqamuzana akho awadingayo, ngaleyo ndlela kukhuphule imetabolism yakho.
6. Gcina impilo yenhliziyo nemithambo yegazi
Ukugcina uhlelo lwenhliziyo olunempilo kubalulekile empilweni yonke. I-calcium alpha-ketoglutarate ingase isekele impilo yenhliziyo ngokusekela ukusebenza kwemisipha ebushelelezi kanye nokulawula umfutho wegazi. Kuyasiza futhi ukuqeda izinto eziyingozi njenge-ammonia emzimbeni, kuqhubeke nokuthuthukisa impilo yenhliziyo nemithambo yegazi.
I-Calcium alpha-ketoglutarate (Ca-AKG) isebenza ngokuthinta izinqubo ezihlukahlukene zebhayoloji emzimbeni. Okulandelayo ezinye zezindlela eziyinhloko zokwenza:
Yenza umjikelezo we-TCA, ukhuthaze imetabolism
I-Ca-AKG iwukhiye omaphakathi kumjikelezo we-tricarboxylic acid (TCA), owaziwa nangokuthi umjikelezo we-Krebs noma umjikelezo we-citric acid. Lo mjikelezo udlala indima ebalulekile ekukhiqizeni amandla eselula. I-Ca-AKG isiza ukwenza lula ukuguqulwa kwama-molecule okudla abe amandla, ikakhulukazi ngesimo se-adenosine triphosphate (ATP). Le nqubo ibalulekile kumetabolism isiyonke.
ukwenza amaprotheni synthesis
I-Ca-AKG kucatshangwa ukuthi ivuselela ukwakheka kwamaprotheni, okubalulekile ekukhuleni kwemisipha, ukulungiswa nokugcinwa. Ngokuthuthukisa ukukhiqizwa kwamaprotheni, isekela ukuthuthukiswa nokugcinwa kwezicubu zemisipha.
Ukukhiqizwa kwe-Nitric oxide (NO).
I-Ca-AKG iphinde ibandakanye ekukhiqizeni i-nitric oxide, i-molecule edlala indima ezinqubweni ezihlukahlukene zomzimba, kuhlanganise ne-vasodilation (ukunwetshwa kwemithambo yegazi). Ukwanda kokukhiqizwa kwe-nitric oxide kuye kwaxhunyaniswa nokugeleza kwegazi okuthuthukisiwe, ukulethwa komoyampilo, kanye nokuthathwa kwezakhi zomzimba zemisipha.
Izakhiwo Ze-Antioxidant
I-Ca-AKG kukholakala ukuthi inezindawo zokulwa ne-antioxidant ezisiza ukunciphisa ukucindezeleka okwenziwe nge-oxidative emzimbeni. Ukucindezeleka okwenziwe nge-oxidative okubangelwa ukungalingani phakathi kwama-radicals mahhala nama-antioxidants kungaholela ekulimaleni kwamaselula nokuvuvukala. Ngokunikeza ukwesekwa kwe-antioxidant, i-Ca-AKG ingaba nomthelela empilweni yonke ye-metabolic.
I-Calcium alpha-ketoglutarate (Ca-AKG) iyinhlanganisela ehlanganisa i-calcium yamaminerali ebalulekile ne-molecule ye-alpha-ketoglutarate. I-Calcium alpha-ketoglutarate (Ca-AKG) iyikhemikhali engapheli engatholakali ngokuqondile ekudleni, kodwa ezinye izifundo zibonise ukuthi ingakhiqizwa ngokudla kanye nendlela yokuphila.
Ukudla kwe-ketogenic kungaba yisinqumo esihle, ukuhlanganisa amafutha namaprotheni, futhi ngokudla ukudla okulinganiselayo okuhlanganisa lokhu kudla, unganikeza umzimba wakho nge-Ca-AKG.
Kodwa-ke, ukuthembela kuphela ekudleni kwe-ketogenic kwe-calcium alpha-ketoglutarate kunezinkinga ezithile. Okokuqala, ukuthola ukudla okunconyiwe kwansuku zonke kwe-Ca-AKG ekudleni kuphela kungaba inselele, ikakhulukazi kubantu abanemikhawulo yokudla noma izintandokazi. Futhi, ukugcwala kwe-Ca-AKG ekudleni kungahluka, okwenza kube nzima ukulawula ukudla kwakho ngqo. Okokugcina, izindlela zokupheka kanye nokucubungula ukudla kungathinta kakhulu amazinga e-Ca-AKG, ngokunokwenzeka kwehlise inani elingamuncwa.
Izithako zeCalcium alpha-ketoglutarate zinikeza indlela elula nethembekile yokuqinisekisa ukuthi uthola amanani anele ale nhlanganisela. Baletha inani elingaguquki lenhlanganisela, okuvumela ukulawula umthamo onembile. Lokhu kunenzuzo ikakhulukazi kubasubathi nakubantu ngabanye abanezinkinga zempilo ezithile abadinga imithamo ephezulu ye-Ca-AKG ukuze bahlangabezane nezidingo zabo.
Nakuba izithasiselo zinazo lezi zinzuzo, kusekhona ezinye izixwayiso okufanele uzikhumbule. Okokuqala, ukulawulwa kwekhwalithi kubaluleke kakhulu lapho ukhetha isengezo se-Ca-AKG. Futhi, izithasiselo akufanele neze zithathe indawo yokudla okunempilo. Ukuthola izakhamzimba ezibalulekile ekudleni okuphelele kuhlala kubalulekile ekugcineni ukudla okunomsoco kanye nempilo iyonke. Okokugcina, ukubonisana nochwepheshe bezokunakekelwa kwempilo noma isazi sezokudla esibhalisiwe kungasiza ekunqumeni umthamo olungile futhi sikuqondise ekukhetheni isithasiselo esifaneleka kakhulu sezidingo zakho ngazinye.
Kubaluleke kakhulu ukulandela umthamo onconywayo futhi uthintane nochwepheshe bezempilo ngaphambi kokuqala noma yiluphi uhlobo lomuthi olusha lwesithasiselo, ikakhulukazi uma unanoma yiziphi izimo zezokwelapha ezicashile noma uphuza imithi. Ukwazi imiphumela emibi engaba khona kanye nokuthatha izinyathelo zokuphepha ezidingekayo kuzosiza ukuqinisekisa ukusetshenziswa okuphephile nokusebenzayo kwe-Ca-AKG.
Ukuphepha
I-Ca-AKG ngokuvamile ibhekwa njengephephile ukusetshenziswa uma isetshenziswa njengoba kuyaliwe. Nokho, kubalulekile ukulandela umthamo onconyiwe ukuze uvimbele noma yimiphi imiphumela emibi engaba khona. Kuhlale kunconywa ukuthi ubonane nochwepheshe bezempilo ngaphambi kokuqala noma yiluphi uhlobo lomuthi olusha lwezithako zokudla, ikakhulukazi uma unomlando wezokwelapha osuvele ukhona noma uthatha noma yimiphi imithi.
umphumela ohlangothini
Nakuba i-Ca-AKG ngokuvamile iphephile, ingase ibangele imiphumela ethile engemihle kwabanye abantu. Le miphumela emibi ivamise ukuba mnene futhi ibe yesikhashana, kodwa kubalulekile ukuyiqaphela. Eminye imiphumela emibi ebikiwe ihlanganisa:
1.Izinkinga zamathumbu: Abanye abantu bangase babhekane nokungakhululeki kokugaya ukudla, okuhlanganisa isicanucanu, ukuqunjelwa, kanye nesifo sohudo. Lezi zimpawu zivame ukudamba ngemva kwezinsuku ezimbalwa njengoba umzimba ulungisa ibhekwa.
2.Ukungezwani komzimba: Ezimweni ezingavamile, abanye abantu bangase babe nokungezwani komzimba ne-Ca-AKG. Izimpawu zingase zihlanganisa ukuqubuka, ukulunywa, ukuvuvukala, isiyezi, noma ukuphefumula kanzima. Uma kwenzeka noma iyiphi yalezi zimpawu, qiniseka ukuthi uyayeka ukusebenzisa futhi ufune usizo lwezokwelapha ngokushesha.
3.Ukusebenzisana nezidakamizwa: I-Ca-AKG ingase ihlanganyele nezidakamizwa ezithile, njengezivimba zesiteshi se-calcium, ama-antibiotics, noma izidakamizwa ezithinta ukujiya kwegazi. Hlala uthintana nochwepheshe bezempilo uma uthatha noma yimiphi imithi ukuze uqinisekise ukuthi akukho ukusebenzisana okungaba khona.
4.Izinkinga zezinso: I-Ca-AKG iqukethe i-calcium, futhi ukudla i-calcium ngokweqile kungase kubangele izinkinga zezinso kubantu abanesifo sezinso. Hlala uthintana nochwepheshe bezempilo ngaphambi kokusebenzisa i-Ca-AKG uma unezinkinga ezihlobene nezinso.
Kubalulekile ukuqaphela ukuthi le miphumela engemihle ayivamile futhi ayibonwa ngabasebenzisi abaningi. Nokho, ukuqapha nokuqapha kufanele ngaso sonke isikhathi kusetshenziswe lapho wethula noma yisiphi isithasiselo sokudla esisha ohlelweni lwakho lwansuku zonke.
Q: Ingabe i-Calcium Alpha Ketoglutarate ingasiza ngokulahleka kwemisipha okuhlobene neminyaka?
A: Yebo, ucwaningo lubonisa ukuthi i-Ca-AKG ingasiza ekulondolozeni isisindo somzimba namandla ancipha ngokwemvelo ngokuguga. Isiza ekuthuthukiseni ukwakheka kwamaprotheni, ngaleyo ndlela isekele ukululama kwemisipha kanye nokunciphisa ukulahleka kwemisipha okuhlobene nobudala.
Q: I-Calcium Alpha Ketoglutarate iyithinta kanjani impilo yamathambo?
A: I-Ca-AKG idlala indima ebalulekile ekugcineni impilo yamathambo ngokuvuselela ama-osteoblasts, amangqamuzana anesibopho sokwakheka kwamathambo. Kuyasiza ekwandiseni ukuminyana kwamathambo nokunciphisa ingozi ye-osteoporosis, isimo esivame ukuhlotshaniswa nokuguga.
Umshwana wokuzihlangula: Lesi sihloko senzelwe izinjongo zokwaziswa kuphela futhi akufanele sithathwe njengeseluleko sezokwelapha. Hlala uthintana nochwepheshe bezempilo ngaphambi kokusebenzisa noma yiziphi izithasiselo noma ukushintsha uhlobo lwakho lokunakekelwa kwezempilo.
Isikhathi sokuthumela: Jul-19-2023
