I-Choline alfoscerate, eyaziwa nangokuthi i-Alpha-GPC, isiphenduke isithasiselo esithuthukisa ukuqonda. Kodwa ngezinketho eziningi ezikhona, ungakhetha kanjani i-choline alfoscerate powder supplement engcono kakhulu? Izithako ezingcono kakhulu ze-choline alfoscerate powder zango-2024 zidinga ukucatshangelwa ngokucophelela ubumsulwa, umthamo, isithunzi somkhiqizo, intengo, nezinye izithako. Ngokucabangela lezi zici, ungathola isengezo sekhwalithi ephezulu esisekela impilo yakho yengqondo futhi sikusize ufinyelele izinjongo zakho zezempilo. Ngaphambi kokuqala noma yisiphi isithasiselo esisha, hlala uthintana nochwepheshe bezempilo ukuze uqiniseke ukuthi kuyisinqumo esilungele wena.
I-Alpha GPCisifinyezo se-alpha-glycerophosphocholine, eyaziwa nangokuthi i-glycerophosphocholine. I-phospholipid equkethe i-choline futhi ingenye yezingxenye eziyinhloko zolwelwesi lwamaseli. Inokuqukethwe okuphezulu kwe-choline. Cishe u-41% wesisindo se-Alpha GPC yi-choline. I-Choline isetshenziswa ekuboniseni amangqamuzana ebuchosheni nasezicubu zezinzwa, futhi izithasiselo ze-Alpha GPC zivame ukuhlanganiswa nezinye izinhlanganisela ezibizwa ngokuthi ama-nootropics. I-Nootropics ikilasi lezidakamizwa kanye/noma izithasiselo ezisiza ukusekela nokuthuthukisa ukusebenza kwengqondo.
Iyini i-choline?
Umzimba ukhiqiza i-alpha GPC kusuka ku-choline. I-Choline iyisakhi esibalulekile esidingwa umzimba ukuze ube nempilo enhle. Nakuba i-choline ingeyona ivithamini noma amaminerali, ngokuvamile ihlobene namavithamini B ngenxa yezindlela ezifanayo zomzimba emzimbeni.
I-Choline iyadingeka ukuze kumetabolism evamile, isebenza njenge-methyl donor, futhi idlala indima ebalulekile ekukhiqizeni ama-neurotransmitters athile njenge-acetylcholine.
I-Choline isakhi esibalulekile esitholakala ngokwemvelo obisini lwebele lomuntu futhi yengezwa obisini lwezingane ezithengiswayo.
Nakuba umzimba ukhiqiza i-choline esibindini, akwanele ukusekela izidingo zomzimba. Ukukhiqizwa kwe-choline okunganele emzimbeni kusho ukuthi i-choline idinga ukutholwa ekudleni. Ukuntuleka kwe-choline kungase kwenzeke uma ukudla kwe-choline kunganele.
Ucwaningo luye lwahlobanisa ukuntula kwe-choline ku-atherosclerosis noma ukuqina kwemithambo yegazi, isifo sesibindi, ngisho nesifo sezinzwa. Ngaphezu kwalokho, kulinganiselwa ukuthi abantu abaningi abakudli ukudla okwanele ekudleni kwabo.
Nakuba i-choline itholakala ngokwemvelo ekudleni okufana nenkomo, amaqanda, i-soy, i-quinoa, namazambane abomvu, ukugcwalisa nge-alpha GPC kungasiza ukwandisa ngokushesha amazinga e-choline emzimbeni.
I-Glycerylphosphocholine iphinde isetshenziswe kabanzi ocwaningweni lwezokwelapha kanye ne-biochemical kanye nezinhlelo zezokwelapha.
1. Ukutholwa kanye nocwaningo lokuqala: I-Glycerylphosphocholine yatholwa okokuqala isazi samakhemikhali ezinto eziphilayo saseJalimane u-Theodor Nicolas Lyman ekuqaleni kwekhulu le-19. Waqale wahlukanisa le nto esitokweni seqanda, kodwa ukwakheka nokusebenza kwayo kwakungakaqondwa ngokugcwele.
2. Ukuhlonzwa kwesakhiwo: Ekuqaleni kwekhulu lama-20, ososayensi baqala ukutadisha ukwakheka kwe-glycerophosphocholine ngokujulile, futhi ekugcineni banquma ukuthi iqukethe i-glycerol, i-phosphate, i-choline nezinsalela ezimbili ze-fatty acid. Lezi zingxenye zixhunywe ngezindlela ezithile ngaphakathi kwe-molecule ukuze zenze ama-molecule e-phospholipid.
3. Imisebenzi yezinto eziphilayo: Kancane kancane kuyaqashelwa ukuthi i-glycerophosphocholine idlala indima ebalulekile kubhayoloji, ikakhulukazi ekwakhiweni nasekugcinweni kolwelwesi lwamangqamuzana. Ibalulekile ekuzinzeni kwe-fluidity kanye nokuzinza kwamangqamuzana e-cell futhi kunemiphumela ekuboniseni, ukuxhumana phakathi kwamaselula, kanye nokuhlanganiswa kwe-choline.
Ukusayinda iseli
Imizimba yethu yenza imisebenzi eminingi ezingeni lamaselula nsuku zonke ngaphandle kokuqaphela. Okufana nokugeleza kwegazi nokushaya kwenhliziyo. Izigidi zamangqamuzana ziyaxhumana ukuze zinikeze umzimba amandla okuqeda le misebenzi futhi usebenze ngendlela efanele. Lokhu kuxhumana phakathi kwamaseli kubizwa ngokuthi "isignali yamaseli". Ama-molecule amaningi ezithunywa athumela amasignali phakathi kwamaseli njengocingo.
Noma nini lapho amaseli ekhuluma wodwa, umfutho kagesi ubangela ukukhululwa kwama-neurotransmitters endaweni ebizwa ngokuthi i-synapse. Ama-Neurotransmitters ahamba esuka kuma-synapses futhi abophe kuma-receptors kuma-dendrites, athola futhi acubungule ulwazi abalutholayo.
I-PGC-1α iboniswa emazingeni aphezulu ku-mitochondria nasezindaweni ezithile ze-metabolism esebenzayo. Lokhu kufaka phakathi ubuchopho, isibindi, amanyikwe, imisipha yamathambo, inhliziyo, uhlelo lokugaya ukudla kanye nesimiso sezinzwa.
Kuyaziwa ukuthi phakathi nenqubo yokuguga, i-mitochondria yeselula yi-organelles eyonakele kakhulu. Ngakho-ke, imvume kanye ne-mitochondrial biogenesis (ukwenza i-mitochondria entsha) ibalulekile ekulinganiseni i-metabolism yamandla. I-PGC-1α idlala indima ebalulekile enqubweni yokulwa nokuguga. Ucwaningo lubonisa ukuthi i-PGC-1α ivimbela i-muscle atrophy ngokulawula i-autophagy (ukuhlanza amaseli). Ucwaningo lwezilwane lubonisa ukuthi amazinga akhulayo we-PGC-1α angathuthukisa izimo zemisipha ehlukene. Umgomo wethu uwukusiza ukukhulisa amazinga e-PGC-1α.
Ku-2014, abacwaningi bacwaninga izilwane ezikhiqiza i-PGC-1α ngokweqile emiculweni yazo yemisipha kanye nezilawuli ezingazange zikhiqize i-PGC-1α eyengeziwe. Ocwaningweni, izilwane zichayeka ezimeni zokucindezeleka okukhulu. Siyazi ukuthi ukucindezeleka ngokuvamile kungase kwenyuse ingozi yokudangala. Kutholakale ukuthi izilwane ezinamazinga aphezulu e-PGC-1α zazinamandla futhi zikwazi kangcono ukubhekana nezimpawu zokucindezeleka kunalezo ezinamazinga aphansi e-PGC-1α. Ngakho-ke, lolu cwaningo luphakamisa ukuthi ukusebenzisa i-PGC-1α kungase kuthuthukise isimo sengqondo.
I-PGC-1α nayo inomphumela othile wokuvikela emisipha. Ama-myoblasts awuhlobo lwengqamuzana yemisipha. Ucwaningo lubonisa ukubaluleka kwendlela ye-PGC-1α-mediated kanye nendima yayo ku-atrophy yemisipha yamathambo. I-PGC-1α ivuselela i-mitochondrial biogenesis ngokwengxenye ngokuphakamisa i-NRF-1 ne-2. Ucwaningo luye lwabonisa ukuthi i-PGC-1α ye-muscle eqondile ibalulekile ku-atrophy ye-skeletal muscle (ukunciphisa ivolumu kanye nobuthakathaka). Uma umsebenzi we-PGC-1α we-mitochondrial biological pathway wanda, umonakalo we-oxidative uyancipha. Ngakho-ke, i-PGC-1α kucatshangwa ukuthi idlala indima yokuvikela ekunciphiseni ukuwohloka kwemisipha yamathambo.
Indlela yokusayina ye-Nrf2
(I-Nrf-2) iyisici esilawulayo esiza ukuvikela kuma-oxidants amaselula ayingozi kumaseli. Ilawula ukuvezwa kwezakhi zofuzo ezingaphezu kuka-300 eziqondiswe ukusiza umzimba, uthuthukise ukuvikelwa kwe-antioxidant futhi usize ukuphendula komzimba okuvuthayo. Ucwaningo lwaselabhorethri lubonisa ukuthi ukusebenzisa i-Nrf-2 kunganweba isikhathi sokuphila ngokuvimbela i-oxidation.
I-Alpha GPC inyusa amazinga e-acetylcholine ebuchosheni. I-acetylcholine iyadingeka ekusebenzeni kwenkumbulo nokusebenza kwengqondo kanye nokusayina phakathi kwama-neurons ezingxenyeni ezihlukahlukene zobuchopho. Amaqanda, inhlanzi, amantongomane, ukholifulawa, i-broccoli kanye nezithako zokudla okunomsoco kuyimithombo ecebile ye-choline.
Kusukelai-alpha GPCikhiqizwa emzimbeni, iguqulwa ibe yi-phosphatidylcholine. I-Phosphatidylcholine, ingxenye eyinhloko ye-lecithin, itholakala kuwo wonke amangqamuzana emzimbeni futhi isetshenziswa ngezindlela eziningi ezahlukene ukusekela umzimba, okuhlanganisa impilo yesibindi, impilo ye-gallbladder, umzimba, nokukhiqizwa kwe-neurotransmitter acetylcholine.
I-Acetylcholine iyisithunywa samakhemikhali esivumela amangqamuzana ezinzwa ukuthi axhumane namanye amangqamuzana ezinzwa, amangqamuzana emisipha, ngisho nezindlala. I-acetylcholine iyadingeka emisebenzini eminingi, kuhlanganise nokulawula ukushaya kwenhliziyo, ukugcina umfutho wegazi, nokulawula ukunyakaza ngaphakathi kwamathumbu.
Nakuba ukuntuleka kwe-acetylcholine kuvame ukuhlotshaniswa ne-myasthenia gravis, amazinga aphansi e-neurotransmitter nawo aye axhunyaniswa nenkumbulo empofu, ubunzima bokufunda, ithoni yemisipha ephansi, ukuwohloka komqondo, nesifo i-Alzheimer's.
Ucwaningo lubonisa ukuthi i-alpha-GPC isiza ukukhulisa i-acetylcholine ebuchosheni ngoba imuncwa ngokushesha futhi yeqe kalula umgoqo wegazi nobuchopho.
Leli khono linikeza i-alpha GPC ezinye izinzuzo zezempilo ezihlukile kakhulu, njengokusiza ukuthuthukisa inkumbulo, ukuthuthukisa ukuqonda, ukuthuthukisa ukusebenza komdlalo, kanye nokwandisa ukukhiqizwa kwehomoni yokukhula.
1. I-Alpha GPC nezithuthukisi zenkumbulo
Ucwaningo luphakamisa ukuthi i-alpha GPC ingasiza ukusekela ukusebenza kwenkumbulo nokwakheka ngenxa yobudlelwane bayo ne-acetylcholine. Njengoba i-acetylcholine ibalulekile ekwakhekeni kwenkumbulo nokugcinwa, i-alpha GPC ingasiza ekukhuthazeni ukwakheka kwenkumbulo.
Ucwaningo lwezilwane olubandakanya amagundane luthole ukuthi ukwesekwa kwe-alpha GPC kwasiza ukuthuthukisa ukusebenza kwenkumbulo ngenkathi kuvikela ubuchopho emiphumeleni eyingozi yokucindezeleka.
Olunye ucwaningo lwezilwane lwathola ukuthi ukugcwalisa nge-alpha GPC kusize ukuthuthukisa ukukhula kwamangqamuzana obuchopho nokuvimbela ukungena kwamangqamuzana obuchopho nokufa ngemva kokuquleka kwesithuthwane.
Kubantu, kuye kwenziwa izifundo ezimbalwa ezihlola ukwesekwa kwe-alpha GPC kumemori namakhono okuqaphela amagama kubantu abanokulahlekelwa ukuzwa okuhlobene neminyaka.
Kodwa-ke, olunye ucwaningo oluhilela abahlanganyeli be-57 abaneminyaka engu-65 kuya ku-85 bathola ukuthi ukwengezwa nge-alpha GPC kwathuthukisa kakhulu amaphuzu okuqashelwa kwamagama ezinyangeni ezingu-11. Iqembu elilawulayo elingazange liyithole i-alpha GPC libe nokusebenza kabi kokubonwa kwegama. Ukwengeza, imiphumela emibi embalwa ibikiwe eqenjini lisebenzisa i-alpha GPC phakathi nocwaningo.
Nakuba i-alpha GPC ingasiza ukuthuthukisa inkumbulo, ucwaningo lubonisa ukuthi ingase isize ukuthuthukisa amakhono engqondo ewonke.
2. I-Alpha GPC kanye nokuthuthukiswa kwengqondo
Ucwaningo luphakamisa ukuthi i-alpha GPC ingasiza ekuthuthukiseni nasekuthuthukiseni amakhono okuqonda ngaphezu kokukhiqiza inkumbulo.
Isibonelo, ucwaningo olulodwa olungaboni kabili, olungahleliwe, olulawulwa yi-placebo lwabandakanya ababambiqhaza besilisa nabesifazane abangaphezu kuka-260 abaneminyaka yobudala engama-60 kuye kwengama-80 abatholakala benesifo i-Alzheimer's esithambile kuya kokulinganisela. Abahlanganyeli bathathe i-alpha GPC noma i-placebo kathathu ngosuku izinsuku eziyi-180.
Ezinsukwini ze-90, ucwaningo lwathola ukuthuthukiswa okuphawulekayo ekusebenzeni kwengqondo eqenjini le-alpha GPC. Ekupheleni kocwaningo, iqembu le-alpha GPC libonise ukuthuthukiswa okuphelele emsebenzini wokuqonda kodwa ukwehla kwezikolo ze-Global Deterioration Scale (GDS). Ngokuphambene, amaphuzu eqenjini le-placebo ahlala efana noma aba mabi kakhulu. I-GDS iwukuhlola okusiza abahlinzeki bezempilo ukuthi bahlole isimo somuntu sokuwohloka komqondo.
Olunye ucwaningo lwathola ukuthi ukwesekwa kwe-alpha GPC kungasiza ukunciphisa ukuncipha kwengqondo kubantu abadala asebekhulile abane-hypertension. Ucwaningo lubandakanya ababambiqhaza asebekhulile abangama-51 abahlukaniswe ngamaqembu ama-2. Iqembu elilodwa lithole izithasiselo ze-alpha GPC, kanti elinye iqembu alizange lithole. Ekulandeleni kwezinyanga ezingu-6, ucwaningo lwathola ukuthuthukiswa okuphawulekayo kumakhono okuqonda eqenjini le-alpha GPC. Ucwaningo lubonisa ukuthi i-alpha-GPC ithuthukisa ubuqotho nokukhula komkhumbi wegazi, isiza ekwandiseni ukugcwala kobuchopho futhi ithuthukise ukusebenza kwengqondo.
Nakuba i-alpha GPC ingasiza ukuthuthukisa amakhono okuqonda, ucwaningo lubonisa ukuthi ingasiza ukuthuthukisa ukusebenza komdlalo.
3. I-Alpha GPC nokuthuthukisa ukusebenza kwezemidlalo
Nakuba ucwaningo lubonisa ukuthi i-alpha GPC ingase izuze ukuqonda, ucwaningo luphinde lubonise ukuthi le nootropic emangalisayo ingaba nezinhlobonhlobo zezinzuzo zomzimba.
Ucwaningo lubonisa ukuthi ukwengeza nge-alpha GPC kungasiza ukuthuthukisa ukusebenza komdlalo namandla. Isibonelo, ucwaningo olulawulwa yi-placebo oluyimpumputhe kabili lubandakanya amadoda asekolishi angu-13 athatha i-alpha GPC izinsuku ezingu-6. Abahlanganyeli baphothule izivivinyo eziningana ezahlukene, okuhlanganisa izivivinyo ze-isometric zomzimba ongaphezulu nophansi. Ucwaningo luthole ukuthi ukwengezwa kwe-alpha GPC kuthuthukisa amandla e-isometric ngaphezu kwe-placebo.
Olunye ucwaningo olungaboni kabili, olungahleliwe, olulawulwa yi-placebo lwalubandakanya abadlali bebhola bebhola basekolishi besilisa abangu-14 abaneminyaka engu-20 kuya kwengu-21. Ababambiqhaza bathathe izithasiselo ze-alpha GPC ihora elingu-1 ngaphambi kokwenza uchungechunge lokuzivocavoca, okuhlanganisa ukugxuma okuqondile, ukuvivinya umzimba kwe-isometric, nokufinyela kwemisipha. Ucwaningo luthole ukuthi ukwengeza nge-alpha-GPC ngaphambi kokuzivocavoca kungasiza ukukhulisa ijubane lokuphakamisa izinsimbi. Ucwaningo luphinde lwathola ukuthi ukufaka i-alpha GPC kungasiza ekunciphiseni ukukhathala okuhlobene nokuzivocavoca.
Ucwaningo lubonisa ukuthi i-alpha GPC ayisizi nje kuphela ukuthuthukisa ukusebenza kwezemidlalo kodwa futhi ingasiza ukukhulisa ukukhiqizwa kwe-hormone yokukhula.
4. I-Alpha GPC kanye nokwanda kwe-hormone yokukhula
I-hormone yokukhula komuntu, noma i-HGH ngamafuphi, i-hormone ekhiqizwa indlala ye-pituitary ebuchosheni. I-HGH iyadingeka empilweni yonke ezinganeni nakubantu abadala. Ezinganeni, i-HGH inesibopho sokwandisa ukuphakama ngokukhuthaza ukukhula kwamathambo noqwanga.
Kubantu abadala, i-HGH ingasiza ekukhuthazeni impilo yamathambo ngokwandisa ukuminyana kwamathambo futhi isekele imisipha enempilo ngokuthuthukisa ukukhula kwemisipha. I-HGH yaziwa nangokuthi ithuthukisa ukusebenza kwezemidlalo, kodwa ukusetshenziswa okuqondile kwe-HGH ngomjovo kuvinjelwe emidlalweni eminingi.
Ngenxa yokuthi ukukhiqizwa kwe-HGH ngokwemvelo kuqala ukuncipha phakathi nokuphila, lokhu kungaholela ekwandiseni ukunqwabelana kwezicubu zamafutha esiswini, ukulahlekelwa kwemisipha, amathambo aphukayo, impilo embi yenhliziyo nemithambo yegazi, ngisho nengozi eyengeziwe yokufa.
Ucwaningo lubonisa ukuthi ukwesekwa kwe-alpha GPC kungasiza ukukhuthaza ukukhiqizwa kwe-hormone yokukhula, ngisho nakubantu abadala abaneminyaka ephakathi.
Ucwaningo oluphindwe kabili oluyimpumputhe, olungahleliwe, olulawulwa yi-placebo lwalubandakanya amadoda angu-7 aneminyaka engu-30 kuya kwengama-37 abenza ukuqeqeshwa kokuphakamisa izinsimbi kanye nokumelana ngemva kokwengeza nge-alpha GPC. Ucwaningo luye lwathola ukuthi ukufaka i-alpha GPC ngaphambi kokuqeqeshwa kwesisindo nokuzivocavoca umzimba kwandisa ukukhiqizwa kwe-hormone yokukhula ngokuphindwe ka-44, esikhundleni sokuphindaphinda okungu-2.6.
Ukwanda kokukhiqizwa kwe-HGH ku-midlife kuhlotshaniswa namafutha omzimba ancishisiwe, ukuzuza okukhulu kwemisipha, nokusebenza kwengqondo okuthuthukisiwe.
I-Alpha GPCiyisengezo se-choline esitholakala kalula esingasiza ekuthuthukiseni inkumbulo, ukuthuthukisa ukuqonda, ukwandisa ukusebenza kwezwe langempela, futhi kwandise ngisho nokukhiqizwa kwama-hormone okukhula nokufihla.
Ukufaka i-alpha GPC ohlelweni olunempilo lwansuku zonke kungase kunikeze izinzuzo zokuphila konke ebuchosheni nasemzimbeni futhi kukhuthaze impilo yonke iminyaka ezayo.
Izindawo zokufaka isicelo:
1. Ukwelashwa kwezokwelapha: I-Choline Alfoscerate isetshenziselwa imithi yokwelapha isibindi esinamafutha, izifo ezithile zezinzwa, izifo zenhliziyo, njll. Akugcini nje ukunikeza amazinga aphezulu e-choline adingwa amangqamuzana obuchopho namangqamuzana ezinzwa, futhi ivikela izindonga zabo zamangqamuzana. Iziguli ezinesifo i-Alzheimer's ikakhulukazi ziba nokuncipha kwenkumbulo nokusebenza kwengqondo, futhi zihambisana nezinkinga ezihlukahlukene, njengokuncipha kokuhamba, ukuphazamiseka kwezinzwa nokunye ukukhubazeka kokusebenza. Imiphumela yokuhlolwa kwemithi yokwelapha kanye nokuhlolwa komtholampilo kuqinisekisile ukuthi i-glycerophosphocholine iwusizo kakhulu emandleni okuqonda nokusebenza kwenkumbulo yobuchopho. Iphinde ibe nezinhlelo zokusebenza ezingase zibe khona ezinhlelweni zokulethwa kwezidakamizwa, okusiza izidakamizwa ukuthi ziwele ulwelwesi lwamaseli ngokuyimpumelelo.
I-2.Izimonyo: I-Choline Alfoscerate ivame ukusetshenziselwa imijovo yezimonyo ukuthuthukisa ukubukeka kwesikhumba.
1.Ipiracetam
I-Piracetam ingenye ye-nootropics endala futhi edume kakhulu. Ingowomndeni we-racemic futhi ivame ukusetshenziselwa ukuthuthukisa ukusebenza kwengqondo nenkumbulo.
Indlela: I-Piracetam iguqula i-neurotransmitter acetylcholine futhi ithuthukise ukuxhumana kwe-neuronal.
Izinzuzo: Isetshenziswa kakhulu ukuthuthukisa inkumbulo, ikhono lokufunda nokugxilisa ingqondo.
Ububi: Abanye abasebenzisi babika ukuthi imiphumela yePiracetam ayicacile futhi ingase idinge ukupakishwa namanye ama-nootropics ukuze bathole izinzuzo ezibonakalayo.
Ukuqhathanisa: Nakuba kokubili i-Alpha GPC ne-Piracetam ithuthukisa ukusebenza kwengqondo, i-Alpha GPC inomthelela oqondile kakhulu kumazinga e-acetylcholine futhi ingase inikeze izinzuzo ezivelele kakhulu zenkumbulo nokufunda.
2. Noopept
I-Noopept iyisidakamizwa esinamandla se-nootropic esaziwa ngezici zayo ezithuthukisa ingqondo. Ivame ukuqhathaniswa ne-piracetam kodwa ithathwa njengenamandla.
I-MECHANISM: I-Noopept inyusa amazinga e-brain-derived neurotrophic factor (BDNF) kanye ne-nerve growth factor (NGF), esekela impilo yobuchopho nokusebenza kwengqondo.
Izinzuzo: Isetshenziselwa ukuthuthukisa inkumbulo, ukufunda, kanye ne-neuroprotection.
Ukungalungi: I-Noopept ingase ibangele eminye imiphumela emibi, njengekhanda elibuhlungu nokucasuka.
Ukuqhathanisa: I-Noopept ne-Alpha GPC bobabili banemiphumela yokuthuthukisa ingqondo, kodwa indlela ye-Noopept ihilela izici ze-neurotrophic, kuyilapho i-Alpha GPC igxile ku-acetylcholine. Kulabo abafuna ukukhulisa amazinga e-acetylcholine, i-Alpha GPC ingaba ngcono.
3. L-Theanine
I-L-theanine i-amino acid etholakala etiyeni eyaziwa ngemiphumela yayo yokupholisa kanye nekhono lokuthuthukisa ukugxila ngaphandle kokubangela ukozela.
Indlela: I-L-theanine inyusa amazinga e-GABA, i-serotonin ne-dopamine, ithuthukisa ukuphumula kanye nokwenza ngcono isimo sengqondo.
Izinzuzo: Isetshenziselwa ukunciphisa ukukhathazeka, ukuthuthukisa ukugxila, nokuthuthukisa isimo sengqondo.
I-Cons: I-L-theanine ivame ukubekezelelwa kahle, kodwa imiphumela yayo icashile kunamanye ama-nootropics.
Ukuqhathanisa: I-L-Theanine ne-Alpha GPC banokusetshenziswa okuhlukile. I-Alpha GPC igxile kakhulu ekuthuthukiseni ukusebenza kwengqondo nge-acetylcholine, kuyilapho i-L-theanine ifaneleka kangcono ukuphumula nokuthuthukisa isimo sengqondo. Ayaphelelisana uma esetshenziswa ndawonye.
4. I-Modafinil
I-Modafinil iyisidakamizwa esikhuthaza ukuphaphama esivame ukusetshenziselwa ukwelapha ukuphazamiseka kokulala. Ibuye idume njengesithuthukisi somqondo.
I-Mechanism: I-Modafinil ithinta ama-neurotransmitters amaningi, kuhlanganise ne-dopamine, i-norepinephrine, ne-histamine, ukukhuthaza ukuphaphama nokusebenza kwengqondo.
Izinzuzo: Isetshenziselwa ukuthuthukisa ukuqapha, ukugxilisa ingqondo, namakhono okuqonda.
Ukungalungi: I-Modafinil ingabangela imiphumela emibi njengokuqwasha, ukukhathazeka, nokukhanda ikhanda. Iphinde ibe isidakamizwa esivela kudokotela emazweni amaningi.
Ukuqhathanisa: I-Modafinil ne-Alpha GPC zombili zithuthukisa umsebenzi wokuqonda, kodwa ngezindlela ezahlukene. I-Modafinil imayelana nokukhuthaza ukuphaphama nokuqapha, kuyilapho i-Alpha GPC igxile ku-acetylcholine nenkumbulo. Ngokusetshenziswa kwesikhathi eside, i-Alpha GPC ingaba inketho ephephile.
Ngaphambi kokuthi sihlole izici zokuphepha, kuyadingeka ukuqonda ukuthi i-Alpha GPC isebenza kanjani. Uma idliwe, i-Alpha GPC iguqulwa ibe yi-choline, ekhuthaza ukuhlanganiswa kwe-acetylcholine. Le neurotransmitter idlala indima ebalulekile emisebenzini ehlukahlukene yengqondo, okuhlanganisa ukunaka, ukufunda, kanye nenkumbulo. Ucwaningo oluningi lubonise ukuthi i-Alpha GPC ingathuthukisa ukusebenza kwengqondo, ikakhulukazi kubantu abadala kanye nabantu abanokukhubazeka kwengqondo.
Izifundo zomtholampilo nokuphepha
1. Izifundo zabantu
Izifundo zomtholampilo eziningi ziphenye ukuphepha nokusebenza kwe-Alpha GPC. Ucwaningo olushicilelwe ku-International Journal of Medical Research lwathola ukuthi ukuthatha i-1,200 mg ye-Alpha GPC nsuku zonke kwakubekezelelwe kahle. Imiphumela emibi ebikwe abahlanganyeli yayincane futhi ngokuvamile imnene, kuhlanganise nobuhlungu bekhanda, isiyezi kanye nezinkinga zesisu.
Olunye ucwaningo olushicilelwe ku-Clinical Therapeutics luhlole ukuphepha kwesikhathi eside kwe-Alpha GPC ezigulini ezinesifo i-Alzheimer's. Ucwaningo luphethe ngokuthi i-Alpha GPC iphephile ukusetshenziswa isikhathi eside, ngaphandle kwemiphumela engemihle ebalulekile ebikiwe.
2. Ucwaningo ngezilwane
Izifundo zezilwane ziphinde zisekele ukuphepha kwe-Alpha GPC. Ucwaningo olushicilelwe ku-Food and Chemical Toxicology luthole ukuthi i-Alpha GPC ayizange ibangele noma yimiphi imiphumela enobuthi kumagundane, ngisho nangemithamo ephezulu. Lokhu okutholakele kukhombisa ukuthi i-Alpha GPC inomkhawulo obanzi wokuphepha, okuyenza isithasiselo esiphephile uma sisetshenziswa ngabantu.
Ubani okufanele agweme i-Alpha GPC?
Nakuba i-Alpha GPC ngokuvamile iphephile kubantu abaningi, abanye abantu kufanele baqaphele:
1. Abesifazane abakhulelwe nabancelisa ibele: Kunocwaningo olulinganiselwe ngokuphepha kwe-Alpha GPC kwabesifazane abakhulelwe nabancelisa ibele. Kunconywa ukuthi uthintane nomhlinzeki wezempilo ngaphambi kokusebenzisa lesi sithasiselo.
2. Abantu abanezinkinga zenhliziyo nemithambo yegazi: I-Alpha GPC ingase ithinte umfutho wegazi nezinga lokushaya kwenhliziyo. Abantu abanesifo senhliziyo nemithambo yegazi kufanele bathintane nomhlinzeki wezempilo ngaphambi kokusetshenziswa.
3. Abantu abaphuza imithi: I-Alpha GPC ingase ihlanganyele nemithi ethile, okuhlanganisa i-anticholinergics kanye nezinto ezinciphisa igazi. Uma uthatha imithi, khuluma njalo nomhlinzeki wakho wezempilo.
1. Ubumsulwa kanye Nekhwalithi
Ukuhlanzeka kanye nekhwalithi ye-Alpha GPC powder kubaluleke kakhulu. Ikhwalithi ephezulu ye-Alpha GPC kufanele ingabi nakungcola nezigcwalisi. Bheka imikhiqizo ehlolelwe ukuhlanzeka namandla. Imikhiqizo eyaziwayo ivamise ukuhlinzeka ngeSitifiketi Sokuhlaziya (COA) ukuze kuqinisekiswe ikhwalithi yomkhiqizo.
2. Umthamo kanye nokugxilisa ingqondo
Izithasiselo ze-Alpha GPC ziyatholakala ngemithamo ehlukahlukene kanye nokugxila. Ukugxila okuvame kakhulu kungu-50% no-99%. I-concentration engu-99% iphumelela kakhulu futhi idinga umthamo omncane ukuze kuzuzwe umphumela oyifunayo. Nokho, ibuye ibize kakhulu. Cabangela isabelomali sakho namandla oyifunayo lapho ukhetha ukugxila.
3. Ifomu lomkhiqizo
I-Alpha GPC itholakala ngezindlela ezahlukene, okuhlanganisa impushana, amaphilisi, noketshezi. Ifomu ngalinye linezinzuzo kanye nokubi. I-Powdered Alpha GPC inemisebenzi eminingi futhi ingaxutshwa kalula nezinye izithasiselo noma iziphuzo. Amaphilisi alula futhi akalwe kusengaphambili, alungele ukuthatha uhambo. I-Liquid Alpha GPC imunca ngokushesha kodwa ingaba nempilo yeshelufu emfushane. Khetha ifomethi evumelana kangcono nendlela yakho yokuphila nezintandokazi zakho.
4. Idumela lomkhiqizo
Idumela lomkhiqizo yisici esibalulekile okufanele sicatshangelwe. Imikhiqizo ehlonishwayo enezibuyekezo ezinhle zamakhasimende cishe izohlinzeka ngemikhiqizo yekhwalithi ephezulu. Cwaninga umlando womkhiqizo, impendulo yekhasimende, nanoma yiziphi izitifiketi okungenzeka banazo. Gwema imikhiqizo enomlando wokukhumbula noma izibuyekezo ezingezinhle.
5. Inani kanye nenani
Intengo ihlale icatshangwa lapho uthenga izithasiselo. Nokho, inketho eshibhe kakhulu ayihlali ingcono kakhulu. Qhathanisa izintengo ngegremu ngayinye noma ukuphakelwa ukuze uthole inani elingcono kakhulu lemali. Cabangela ikhwalithi yomkhiqizo, ukugxila kwawo, kanye nanoma yiziphi ezinye izinzuzo ongase uzinikeze.
6. Ezinye izithako
Eminye imikhiqizo ye-Alpha GPC ingase iqukethe ezinye izithako, njengamanye ama-nootropics, amavithamini noma amaminerali. Lezi zithako ezingeziwe zingathuthukisa ukusebenza kahle okuphelele kwesengezo. Kodwa-ke, futhi zandisa ingozi yemiphumela emibi noma ukusebenzisana neminye imithi. Funda ilebula ngokucophelela futhi ubuze uchwepheshe wakho wezempilo uma unemibuzo.
7. Ukubuyekezwa Kwekhasimende kanye Nobufakazi
Ukubuyekezwa kwekhasimende nobufakazi kunganikeza imininingwane ebalulekile ekusebenzeni kahle komkhiqizo nekhwalithi. Bheka izibuyekezo ezivela kubathengi abaqinisekisiwe futhi uqaphele noma yiziphi izinkinga ezivelayo noma izincomo. Khumbula ukuthi ukuzizwisa komuntu ngamunye kungase kuhluke, kodwa amaphethini empendulo eyakhayo noma engemihle angabonisa ikhwalithi iyonke yomkhiqizo.
I-Suzhou Myland Pharm & Nutrition Inc. ingumkhiqizi obhalisiwe we-FDA ohlinzeka ngempushana ye-Alpha GPC yekhwalithi ephezulu kanye nobumsulwa.
KwaSuzhou Myland Pharm sizibophezele ekuhlinzekeni ngemikhiqizo esezingeni eliphezulu ngamanani angcono kakhulu. I-Alpha GPC yethu powder ihlolelwa ngokuqinile ubumsulwa namandla, iqinisekisa ukuthi uthola isengezo sekhwalithi ephezulu ongasethemba. Kungakhathaliseki ukuthi ufuna ukusekela impilo yeselula, ukuqinisa amasosha akho omzimba noma uthuthukise impilo yonke, i-Alpha GPC yethu powder iyisinqumo esihle kakhulu.
Njengoba inesipiliyoni seminyaka engu-30 futhi iqhutshwa ubuchwepheshe obuphezulu kanye namasu e-R&D athuthukiswe kakhulu, i-Suzhou Myland Pharm isungule uhide lwemikhiqizo encintisanayo futhi yaba isithasiselo sesayensi yempilo emisha, ukuhlanganisa ngokwezifiso kanye nenkampani yezinkonzo zokukhiqiza.
Ngaphezu kwalokho, iSuzhou Myland Pharm iphinde ibe ngumkhiqizi obhalisiwe we-FDA. Izinsiza ze-R&D zenkampani, izikhungo zokukhiqiza, namathuluzi okuhlaziya kungokwesimanjemanje futhi kunemisebenzi eminingi, futhi ingakhiqiza amakhemikhali ukusuka kumamiligremu ukuya kumathani esikalini, futhi ihambisane namazinga e-ISO 9001 kanye nemininingwane yokukhiqiza ye-GMP.
Q: Iyini i-Alpha-GPC?
A:Alpha-GPC (L-Alpha glycerylphosphorylcholine) iyinhlanganisela yemvelo ye-choline etholakala ebuchosheni. Iyatholakala futhi njengesengezo sokudla futhi yaziwa ngezici zayo ezithuthukisa ingqondo. I-Alpha-GPC ivame ukusetshenziselwa ukusekela impilo yobuchopho, ukuthuthukisa inkumbulo, nokuthuthukisa ukucaca kwengqondo.
Q:Isebenza kanjani i-Alpha-GPC?
A:I-Alpha-GPC isebenza ngokwandisa amazinga e-acetylcholine ebuchosheni. I-Acetylcholine iyi-neurotransmitter edlala indima ebalulekile ekwakhekeni kwenkumbulo, ukufunda, kanye nomsebenzi wokuqonda jikelele. Ngokwandisa amazinga e-acetylcholine, i-Alpha-GPC ingasiza ukuthuthukisa ukusebenza kwengqondo futhi isekele impilo yobuchopho.
Q:3. Yiziphi izinzuzo zokuthatha i-Alpha-GPC?
A:Izinzuzo eziyinhloko zokuthatha i-Alpha-GPC zifaka:
- Inkumbulo ethuthukisiwe namakhono okufunda
- Ukucaca nokugxila kwengqondo okuthuthukisiwe
- Ukusekela impilo yobuchopho jikelele
- Imiphumela engaba khona ye-neuroprotective, engasiza ekuvimbeleni ukuncipha kwengqondo
- Ukwenyuka kokusebenza komzimba, ikakhulukazi kubasubathi, ngenxa yendima yayo ekukhuthazeni ukukhululwa kwe-hormone yokukhula
Umshwana wokuzihlangula: Lesi sihloko esolwazi oluvamile kuphela futhi akufanele sithathwe njengeseluleko sezokwelapha. Olunye ulwazi lokuthunyelwe kwebhulogi luvela ku-inthanethi futhi alusebenzi. Le webhusayithi inomthwalo wemfanelo kuphela wokuhlunga, ukufometha kanye nokuhlela ama-athikili. Injongo yokudlulisa ulwazi olwengeziwe ayisho ukuthi uyavumelana nemibono yayo noma uqinisekise ubuqiniso bokuqukethwe kwayo. Hlala uthintana nochwepheshe bezempilo ngaphambi kokusebenzisa noma yiziphi izithasiselo noma wenze izinguquko ohlelweni lwakho lokunakekelwa kwezempilo.
Isikhathi sokuthumela: Sep-23-2024
