Ukuphishekela impilo enempilo, elinganiselayo, sivame ukuphendukela ezinhlobonhlobo zezithasiselo zokuthuthukisa impilo yethu. I-N-Acetyl-L-Cysteine Ethyl Ester (NACET) iyisengezo esinamandla esizuza ukudonswa emphakathini wezempilo nokuphila kahle. Kusukela ekusekelweni kwe-antioxidant nokuphefumula kuya emiphumeleni empilweni yengqondo nesibindi, le nhlanganisela eyingqayizivele iboniswe ukuthi inezinhlobonhlobo zezinzuzo. I-NACET inikeza izinzuzo eziningi kulabo abafuna indlela ephelele yezempilo. Ngokuhlanganisa i-NACET empilweni yakho yansuku zonke, ungakwazi ukukhuthala futhi uzuze impilo enempilo, elinganiselayo.
I-N-acetyl-L-cysteine ethyl ester, eyaziwa nangokuthi i-NACET, iyi-antioxidant enamandla ne-amino acid. Lesi sengezo sithathwe ku-amino acid L-cysteine, ebalulekile ekukhiqizeni i-glutathione. (i-antioxidant ebaluleke kakhulu yomzimba), iwuhlobo olusha lwe-ethyl ester lwe-NAC oluqashelwa imboni yezithasiselo ngezinzuzo zayo eziningi zezempilo.
I-NACET yaziwa ngamandla ayo okukhulisa amazinga e-glutathione emzimbeni, ebamba iqhaza elibalulekile ekukhipheni ubuthi kanye nokusebenza kokuzivikela komzimba. Iphinde ibe nezindawo zokulwa nokuvuvukala kanye ne-mucolytic, okuyenza ibe isengezo esibalulekile ezindabeni zezempilo ezahlukahlukene. I-NACET itholakala ngokuphindwe izikhathi ezingu-20 ku-bioavailable evamile kune-glutathione ejwayelekile kanye nezithasiselo ze-NAC. Lokhu kusho ukuthi uma uthatha i-NACET, umzimba wakho uyisebenzisa ngokuphumelelayo.
Lokhu kutholakala kwe-bioavailability okuthuthukisiwe kuhumusheka emiphumeleni esebenza ngempumelelo ye-antioxidant, ikakhulukazi ekwandiseni amazinga e-antioxidant glutathione (GSH), eyaziwa ngokuthi i-antioxidant enamandla kakhulu emzimbeni.
Ikhono le-NACET lokuvikela ekulimaleni kwe-oxidative kumaseli kuyenza inkemba esika nhlangothi zombili yokunakekela impilo. Akusizi nje kuphela ukuvikela ubuchopho emonakalweni wama-radical wamahhala, futhi isekela nokusebenza kwengqondo,
Sekukonke, i-N-acetyl-L-cysteine ethyl ester iyisengezo esibalulekile esinezinhlobonhlobo zezinzuzo zezempilo. Kungakhathaliseki ukuthi ufuna ukusekela impilo yokuphefumula, ukuthuthukisa impilo yengqondo, noma ukuvikela isibindi sakho, i-NACET iyindlela ethembisayo okufanele icatshangelwe. Ngezindawo zayo zokulwa nokuvuvukala, eziqeda ukuvuvukala kanye ne-detoxifying, i-NACET inamandla okuba nomthelela omuhle empilweni kanye nempilo enhle.
I-N-Acetyl-L-Cysteine (NAC)iyisengezo esaziwa ngokukwazi ukusekela impilo yesibindi, ukwandisa amazinga e-glutathione, futhi senze njenge-antioxidant emzimbeni. Ivame ukusetshenziselwa ukusiza ukwelapha ukweqisa kwe-acetaminophen nokusekela impilo yokuphefumula. I-NAC isebenza ngokugcwalisa amazinga omzimba e-cysteine, isandulela se-glutathione, isivikelo esinamandla sokulwa ne-antioxidant.
Ngakolunye uhlangothi, i-N-acetyl-L-cysteine ethyl ester (NACET) iphuma ku-N-acetyl-L-cysteine. Leli fomu likhiqizwa ngokufaka esterifying amaqembu e-carboxylic acid e-NAC nge-ethanol. Lokhu kuguqulwa kuthiwa kuthuthukisa ukunyibilika kwe-compound kanye ne-bioavailability, okuvumela ukumuncwa okungcono emzimbeni.
Omunye womehluko omkhulu phakathi kwe-NAC ne-NACET ukutholakala kwazo nge-bioavailability. I-NAC ayimuntshwanga kahle umzimba uma ithathwa ngomlomo, futhi iningi layo ligaywa libe kwezinye izinhlanganisela ngaphambi kokuthi liqale ukusebenza. Ngakolunye uhlangothi, i-NACET ibhekwa njengetholakala kakhulu ngenxa yoshintsho ekwakhekeni kwamakhemikhali, okuyenza ibe inketho esebenza kangcono kulabo abafuna ukuvuna izinzuzo ze-N-acetyl-L-cysteine.
Ngaphezu kokutholakala kwe-bioavailability, lezi zinhlobo ezimbili zingase zehluke ekuzinzeni nasekuphileni kweshelufu. I-NAC yaziwa ngokungazinzi ngandlela thize futhi ingehlisa isithunzi ngokuhamba kwesikhathi, ikakhulukazi uma ichayeke ekushiseni, ekukhanyeni, noma ekuswakeni. I-NACET inesakhiwo esilungisiwe esingase sinikeze ukuzinza okukhulu kanye nempilo yeshelufu ende, okuyenza ibe inketho elula kwabanye abasebenzisi.
I-N-acetyl-L-cysteine ethyl ester, evame ukufushaniswa njenge-NACET, iwuhlobo olushintshiwe lwe-amino acid cysteine futhi ivame ukusetshenziswa njengesengezo sokudla ukuze kusekelwe izici zempilo kusukela ekusebenzeni kokuphefumula kuya ekuqedeni ngokuphelele.
Ngenxa yezakhiwo zayo ezingaba khona ze-neuroprotective, i-NACET isetshenziselwa ukusekela impilo yobuchopho, ithuthukise ukusebenza kwengqondo, futhi ingase isize ekulawuleni izifo ze-neurodegenerative. Ukwengeza, i-NACET ikhuthaza ukukhiqizwa kwe-glutathione, i-antioxidant eyinhloko ebuchosheni. Lokhu kusiza ukunciphisa ukucindezeleka okwenziwe nge-oxidative nokulimala kwe-neuronal, okubalulekile ekugcineni impilo yengqondo. Ukwengeza, ngokwandisa amazinga e-antioxidant, i-NACET ivikela amangqamuzana obuchopho ekucindezelekeni kwe-oxidative, okungase kuthikameze ukusebenza kwengqondo futhi kuholele ezifweni ze-neurodegenerative.
Enye yezinto ezisetshenziswa kakhulu i-NACET impilo yokuphefumula. Kuye kwaboniswa ukusekela izivikeli zemvelo zomzimba ngokumelene nesifo sokuphefumula, okwenza kube ukukhetha okuthandwayo kulabo abafuna ukugcina ukusebenza kwamaphaphu anempilo. Ngaphezu kwalokho, i-NACET iye yacwaningelwa amandla ayo okunciphisa ukuminyana kanye nokwenza ngcono impilo yonke yokuphefumula.
Ngaphezu kwezinzuzo zayo zokuphefumula, i-NACET nayo idlala indima ebalulekile ekukhipheni ubuthi. Njenge-antioxidant enamandla, isiza ukunciphisa ama-radicals mahhala futhi ikhuthaze ukuqedwa kobuthi emzimbeni. Lokhu kwenza i-NACET ibe yithuluzi elibalulekile kulabo abafuna ukusekela impilo yesibindi kanye nenqubo yokuqeda ubuthi obuphelele.
Ukwengeza, i-NACET itholakale isekela impilo yengqondo nokusebenza kwengqondo. Ucwaningo lukhombisa ukuthi lungasiza ukuvikela ubuchopho ekucindezelekeni kwe-oxidative futhi kukhuthaze ukusebenza kwe-neurotransmitter enempilo. Lokhu kwenza i-NACET ibe isithasiselo esithembisayo kulabo abafuna ukusekela ukucaca kwengqondo, ukugxila, kanye nempilo yonke yobuchopho.
Okunye okugqamile kwe-NACET yikhono layo lokusekela ukusebenza kwawo wonke amasosha omzimba. Ngokunciphisa ingcindezi ye-oxidative nokukhuthaza ukusabela okunempilo kokuvuvukala, i-NACET ingasiza ekuqiniseni ukuzivikela okungokwemvelo komzimba ekuthelelekeni nasezifweni.
I-NACET inyusa amazinga e-antioxidant. I-NACET iphumelela kakhulu ekwandiseni ukukhiqizwa komzimba kwe-glutathione, i-antioxidant enamandla. Lokhu kwenza kube usizo ekulweni nengcindezi ye-oxidative nokuvikela amaseli emonakalweni.
Ngakho, ubani ongazuza ngokusebenzisa i-NACET? Iqiniso liwukuthi, cishe noma ubani angathola imivuzo ngokuhlanganisa lesi sengezo esinamandla esimisweni sakhe sezempilo. Kungakhathaliseki ukuthi ufuna ukusekela impilo yokuphefumula, ukukhuthaza ukukhipha ubuthi, ukulondoloza amasosha omzimba anempilo, noma ukusekela ukusebenza kwengqondo, i-NACET ingasiza.
Isikhathi esingcono kakhulu sokuthatha i-NACET ekugcineni sincike kumuntu nezinjongo zakhe zezempilo ezithile. Abanye abantu bakuthola kuzuzisa ukuthatha i-NACET ekuseni njengengxenye yendlela yabo yansuku zonke, kuyilapho abanye bekhetha ukuyiphuza ngaphambi kokulala. Nazi ezinye izinto okufanele zicatshangelwe lapho unquma ukuthi uyithatha nini i-NACET:
1. Ukukhipha ubuthi emzimbeni: I-NACET yaziwa ngekhono layo lokusekela izindlela zokuqeda ubuthi emzimbeni. Uma umgomo wakho oyinhloko ekuthatheni i-NACET uwukusekela impilo yesibindi kanye nokuqeda ubuthi, ukuyiphuza ekuseni kungase kusebenze kakhulu. Lokhu kungenxa yokuthi isibindi sisebenza kakhulu ekuseni, futhi ukuthatha i-NACET ngalesi sikhathi kungase kusize ukuthuthukisa ukusebenza kwaso kokukhipha ubuthi.
2. Ukusekelwa Kwe-Antioxidant: I-NACET iyi-antioxidant enamandla esiza ukunciphisa ama-radicals mahhala futhi inciphise ukucindezeleka okwenziwe nge-oxidative emzimbeni. Uma isizathu sakho esikhulu sokuthatha i-NACET siwukusekela isivikelo se-antioxidant sisonke, kungase kube usizo ukukuthatha usuku lonke nokudla ukuze usize ukususa umonakalo owenziwe yi-oxidative obangelwa ukusetshenziswa kokudla.
3. Ukusebenza Kokusubatha: Abanye abantu bathatha i-NACET ukuze basekele ukusebenza kwezokusubatha nokululama. Kulokhu, ukuthatha i-NACET ngaphambi kokuzivocavoca kungase kusize ukuqinisa izivikeli mzimba futhi kunciphise ukukhathala kwemisipha. Ukwengeza, ukuthatha i-NACET ngemva kokuzivocavoca kungasiza ukusekela ukululama kwemisipha futhi kunciphise umonakalo owenziwe yi-oxidative obangelwa umsebenzi onzima womzimba.
4. Ukwesekwa Kokulala: I-NACET iphinde yenza ucwaningo mayelana namandla ayo okusekela izinga lokulala nobude besikhathi. Uma uthatha i-NACET ukuze ukhuthaze ukulala okungcono, ungathola ukuthi ukuyiphuza kusihlwa noma ngaphambi kokulala kukusiza ukuthi uphumule futhi uthuthukise ikhwalithi yakho yonke yokulala.
Kuyaphawuleka ukuthi i-NACET ingathathwa ngokudla noma ngaphandle kokudla, njengoba imuncwa kahle ngumzimba nganoma iyiphi indlela. Ukwengeza, umthamo onconyiwe we-NACET ungahluka kuye ngezidingo zomuntu ngamunye kanye nokukhathazeka kwezempilo. Ngaphambi kokuqala noma yiluphi uhlobo lwemithi yokwelapha entsha, kungcono ukuthintana nochwepheshe bezempilo ukuze uqinisekise ukuthi iphephile futhi ifanele izidingo zakho zezempilo ezithile.
Okokuqala, kubalulekile ukucwaninga umkhiqizo nomkhiqizi ngemuva kwesithasiselo se-N-acetyl-L-cysteine ethyl ester osicabangayo. Bheka inkampani enerekhodi eliqinisekisiwe lokukhiqiza izithasiselo zekhwalithi ephezulu, ezimsulwa, nezisebenzayo. Ukuhlola ukuhlolwa nezitifiketi ezivela eceleni kungaqinisekisa ikhwalithi nokusebenza komkhiqizo.
Okulandelayo, bhekisisa izithako kanye nefomula yezithako ze-N-acetyl-L-cysteine ethyl ester. Ngokufanelekile, ufuna ukukhetha isithasiselo esingenazo izithasiselo ezingadingekile, izigcwalisi, kanye nokungezwani komzimba. Ukukhetha imikhiqizo esebenzisa i-bioavailable futhi amunca kalula i-N-acetyl-L-cysteine ethyl ester nakho kungakhulisa ukusebenza kahle kwayo emzimbeni.
Futhi cabangela umthamo kanye nokuhlushwa kwe-N-acetyl-L-cysteine ethyl ester ekwengezeni. Kuye ngezinjongo zakho ezithile zezempilo kanye nezidingo, ungase udinge umthamo ophezulu noma ophansi. Kungcono ukubonana nochwepheshe bezempilo ukuze uthole umthamo okulungele wena.
Esinye isici esibalulekile okufanele sicatshangelwe idumela nokubuyekezwa kwe-N-acetyl-L-cysteine ethyl ester supplements. Ukufunda impendulo evela kwabanye abasebenzisi kunganikeza imininingwane ebalulekile ekusebenzeni komkhiqizo, imiphumela engemihle engaba khona, nokwaneliseka kukonke. Khumbula, okuhlangenwe nakho kwawo wonke umuntu ngezithasiselo kungase kuhluke, ngakho-ke kubalulekile ukubhekana nezibuyekezo ngomqondo ovulekile.
Ukwengeza, kuwukuhlakanipha ukucabangela izindleko nenani lezithasiselo ze-N-acetyl-L-cysteine ethyl ester. Yize intengo kungafanele kube yiyona kuphela into enqumayo, kubalulekile ukuthola umkhiqizo olingana nesabelomali sakho ngaphandle kokuyekethisa ikhwalithi.
Okokugcina, cabangela noma yiziphi ezinye izici noma izinzuzo ezinganikezwa yi-N-acetyl-L-cysteine ethyl ester supplements. Isibonelo, eminye imikhiqizo ingase ibe nezithako ezengeziwe ezingeziwe noma izindlela zokulethwa ezihlukile zokuthuthukisa ukusebenza kwayo. Ukuhlola lezi zinzuzo ezengeziwe kungakusiza uthole isengezo esifanelana nezintandokazi zakho nendlela yokuphila.
Inkampani engu-Suzhou Myland Pharm & Nutrition Inc. ibambe iqhaza ebhizinisini lezithako zokudla okunomsoco kusukela ngo-1992. Yinkampani yokuqala eShayina ukuthuthukisa nokudayisa imbewu yamagilebhisi.
Njengoba inesipiliyoni seminyaka engu-30 futhi iqhutshwa ubuchwepheshe obuphezulu kanye namasu e-R&D athuthukiswe kakhulu, inkampani ithuthukise uhla lwemikhiqizo encintisanayo futhi yaba isithasiselo sesayensi yempilo emisha, ukuhlanganisa ngokwezifiso kanye nenkampani yezinkonzo zokukhiqiza.
Ngaphezu kwalokho, inkampani iphinde ibe ngumkhiqizi obhalisiwe we-FDA, oqinisekisa impilo yabantu ngekhwalithi ezinzile nokukhula okuqhubekayo. Izinsiza ze-R&D zenkampani kanye nezindawo zokukhiqiza kanye namathuluzi okuhlaziya kungokwesimanje futhi anemisebenzi eminingi, futhi ayakwazi ukukhiqiza amakhemikhali esikalini se-milligram kuya kuthani ngokuhambisana namazinga e-ISO 9001 kanye nezinqubo zokukhiqiza ze-GMP.
Q: Iyini iCalcium Alpha Ketoglutarate?
A: I-Calcium Alpha Ketoglutarate iyisengezo esihlanganisa i-calcium ne-alpha ketoglutaric acid, okuyinhlanganisela edlala indima ebalulekile ekukhiqizeni amandla kanye ne-metabolism yezakhi emzimbeni.
Q: Yiziphi izinzuzo zokuthatha izithasiselo zeCalcium Alpha Ketoglutarate?
A: Izithako ze-Calcium Alpha Ketoglutarate ziye zaboniswa ukusekela impilo yamathambo, ukuthuthukisa ukusebenza kwemisipha, ukuthuthukisa ukukhuthazela kokuzivocavoca, nokukhuthaza impilo yonke kanye nokuphila kahle.
Q: Ingabe izithasiselo zeCalcium Alpha Ketoglutarate zingazuzisa abasubathi nabathanda ukuqina?
A: Yebo, izithasiselo zeCalcium Alpha Ketoglutarate zingathuthukisa ukusebenza kokuzivocavoca nokukhuthazela ngokuthuthukisa ukukhiqizwa kwamandla kanye ne-metabolism yezakhi emzimbeni.
Umshwana wokuzihlangula: Lesi sihloko esolwazi oluvamile kuphela futhi akufanele sithathwe njengeseluleko sezokwelapha. Olunye ulwazi lokuthunyelwe kwebhulogi luvela ku-inthanethi futhi alusebenzi. Le webhusayithi inomthwalo wemfanelo kuphela wokuhlunga, ukufometha kanye nokuhlela ama-athikili. Injongo yokudlulisa ulwazi olwengeziwe ayisho ukuthi uyavumelana nemibono yayo noma uqinisekise ubuqiniso bokuqukethwe kwayo. Hlala uthintana nochwepheshe bezempilo ngaphambi kokusebenzisa noma yiziphi izithasiselo noma wenze izinguquko ohlelweni lwakho lokunakekelwa kwezempilo.
Isikhathi sokuthumela: Feb-26-2024
