Ukuxhumana phakathi kwengcindezi yeselula neMitoquinone, kungani kubalulekile empilweni yakho?

Ezingeni elilula, ingqamuzana liyisaka loketshezi elizungezwe ulwelwesi. Akuzwakali kuxakile, kodwa okumangalisayo ukuthi ngaphakathi kwalolu ketshezi, amanye amakhemikhali nama-organelle enza imisebenzi ekhethekile ehlobene nomsebenzi wengqamuzana ngalinye, njengokusiza amangqamuzana e-iris esweni alawule ukuhamba kokukhanya.

Okubaluleke kakhulu, amangqamuzana ethu nawo athatha amafutha, njengokudla esikudlayo nomoya esiwuphefumulayo, futhi awaguqule abe amandla. Ngokuhlaba umxhwele, amangqamuzana angakwazi ukusebenza ngokuzimela, akhiqize amandla awo, futhi aziphindaphinde—empeleni, amangqamuzana ayiyunithi encane yokuphila ekwazi ukuziphindaphinda. Ngakho, amangqamuzana awagcini nje ngokuhlanganisa izinto eziphilayo; bayizinto eziphilayo ngokwabo.

Amaseli anempilo ayaguga, alungise futhi akhule kahle, akhiqiza amandla anele ukuze asebenze, futhi alawula impendulo yakho yokucindezeleka ukuze ugcine umzimba wakho nengqondo isebenza kahle. Ngakho-ke, uwagcina kanjani amaseli akho enempilo ukuze uqinisekise ukuthi konke kuhamba kahle?

Ngingawagcina kanjani amaseli ami enempilo?

Njengoba umzimba womuntu wenziwe cishe ngokuphelele ngamaseli, lapho sicabanga ngokuphila "okunempilo", sikhuluma ngokugcina amangqamuzana enempilo. Ngakho-ke imithetho evamile iyasebenza: yidla ukudla okulinganiselayo, gcina amazinga amahle okuzivocavoca, ungabhemi, qiniseka ukuthi ulala ngokwanele usuku ngalunye, futhi unciphise ukucindezeleka empilweni (futhi unciphise isidingo sokusabela kokucindezeleka kwamaselula), ukuphuza utshwala, nokuchayeka. ubuthi bemvelo. Okuqukethwe kwencwadi yokufunda.

Kodwa kunezinyathelo ezimbalwa okungenzeka awuzazi, futhi kulapho sidinga khona ukufunda kabanzi mayelana nomhlaba omangalisayo wamaseli. Ngoba nsuku zonke, ukucindezeleka kungenzeka ngaphakathi kwamangqamuzana akho, okungathinta yonke into kusukela kumazinga akho wamandla kuya kumakhono akho okuqonda, ukuthi ukhula kanjani, ululama kanjani ekuzivivinyeni nasekuguleni, kanye nempilo yakho yonke.

Njengoba sishilo ngaphambili, amangqamuzana akho akhiqiza amandla awo, kodwa yini ngempela edala lawo mandla? Ngaphakathi kwamaseli akho, unama-organelles amancane abizwa ngokuthi i-mitochondria. Mancane kakhulu, kodwa anomthwalo wemfanelo wokukhiqiza u-90% wamandla omzimba wakho. Lokho kungamaphesenti angama-90 wamandla owasebenzisa nsuku zonke, okuhlanganisa nokuzivocavoca ngoMsombuluko, ukukhumbula ukushayela umama ucingo, ukuqala ngalowo mbiko wango-9 ebusuku obungafuni ukuwubhala, nokusiza izingane zakho ukuthi zilale zingancibiliki. Lapho ingxenye yomzimba wakho idinga amandla engeziwe ukuze isebenze (njengenhliziyo, imisipha, noma ubuchopho), yilapho amangqamuzana e-mitochondria kufanele ahlangabezane nalezi zidingo zamandla aphezulu.

Njengokungathi lokho bekukukhulu ngokwanele, i-mitochondria yakho iphinde isize amangqamuzana akho akhule, aphile, futhi afe, asize ukukhiqiza amahomoni, asize ngokugcinwa kwe-calcium ekuboniseni amaseli, futhi abe ne-DNA yawo eyingqayizivele ukuwasiza enze imisebenzi yawo ekhethekile. Kodwa ngeshwa, lezi izingxenye ezincane zomzimba wakho lapho izinto zingahamba kabi.

Kuyini ukucindezeleka kwamaselula?

Lapho i-mitochondria yakho ikhiqiza amandla ukuze usebenze, iphinde ikhiqize umkhiqizo obizwa ngokuthi ama-radicals wamahhala, okufana nokukhipha enjini yemoto. Ama-radicals wamahhala awawona wonke amabi, futhi adlala izindima ezibalulekile, kodwa uma enqwabelana ngokweqile, angabangela ukulimala kwamaseli. Lesi yimbangela eyinhloko yokucindezeleka kwamaselula emzimbeni (ezinye izimbangela zihlanganisa izingcindezi zemvelo, izifo ezithile, nokulimala ngokomzimba). Uma lokhu sekwenzekile, amangqamuzana akho achitha amandla ayigugu nesikhathi elwa nomonakalo, noma eqala izimpendulo zengcindezi yeselula, futhi awakwazi ukwenza wonke umsebenzi obalulekile umzimba wakho owudingayo ukuba awenze.

Kodwa-ke, i-mitochondria yakho ihlakaniphile - ibizwa ngokuthi i-powerhouse yeseli ngesizathu esihle! Bazilawula ngokwabo ukuqoqwa kwama-radicals mahhala ngokukhiqiza ama-antioxidants, azinzisa lawa ma-radicals wamahhala anenkani futhi anciphise amandla okucindezeleka kwamaselula.

I-mitochondria yakho ayithuthuki ngokuya ngeminyaka. Njengoba ukhula, amazinga e-antioxidant emzimbeni wakho ehla ngokwemvelo, okwenza ama-radicals mahhala angalawuleki. Ngaphezu kwalokho, ukuphila kwethu kwansuku zonke kusichaya kuma-radicals amaningi amahhala ngokusebenzisa izingcindezi ezinjengokungcola, imisebe ye-UV, ukudla okungenamsoco, ukungazivocavoci, ukungalali kahle, ukubhema, ingcindezi yokuphila, kanye nokuphuza utshwala, okwenza kube nzima ukulwa nokukhululeka. ama-radicals.

Ukucindezeleka kwamaselula kusho ukuthi amangqamuzana akho ayahlaselwa - yilapho "ukuguga nokuphila" kungena khona. Nsuku zonke, amangqamuzana akho asengozini yokulimala ukulahlekelwa ama-antioxidants ngesikhathi sokuguga kanye nomunye umonakalo owenzeka kuyo yonke impilo ".

Kungani kufanele ube nendaba nokucindezeleka kwamaselula?

Le nhlanganisela yezici zangaphakathi nezingaphandle yenza buthaka ikhono leseli lokubhekana nesimo. Esikhundleni sokusebenza kahle, amaseli ethu aya ngokuya ecindezeleka, okusho ukuthi sihlala sikwimodi yokucisha umlilo ukuze sigcine imizimba yethu isebenza kahle. Kithina, lokhu kusho ukuzizwa ukhathele kakhulu, ukuba namandla aphansi ntambama, ukuba nenkinga yokugxilisa ingqondo emsebenzini, ukuzizwa ukhathele ngosuku olungemva kokuzivivinya kanzima, ukululama kancane ekuguleni, kanye nomuzwa noma ukubona imiphumela yokuguga igqama kakhulu. Ngamanye amazwi, kuzwakala kubi.

Kunengqondo-ke ukuthi uma amangqamuzana akho esezingeni eliphezulu, nawe uzobe ungcono kakhulu. Izigidigidi zamaseli emzimbeni wakho zakha isisekelo sempilo yakho. Uma amangqamuzana akho enempilo, umphumela omuhle we-domino uyenzeka, okuhlanganisa ukugqugquzela impendulo yakho yokuzivikela engokwemvelo, esekela impilo yomzimba wakho wonke ukuze uphile impilo yakho ngempela.

I-Mitoquinone isiza kanjani ukulwa nengcindezi yamaselula?

Ukucindezeleka kwamaselula kwenzeka lapho amaseli ethu echayeka ezintweni eziphazamisa ukusebenza kwawo okuvamile. Lokhu kungabandakanya ukucindezeleka kwe-oxidative, okwenzeka lapho kunokungalingani phakathi kokukhiqizwa kwama-radicals mahhala ayingozi kanye nekhono lomzimba lokuwanciphisa. Ukwengeza, ubuthi bemvelo, ukudla okungenamsoco, ngisho nokucindezeleka okungokwengqondo konke kungaba nomthelela ekucindezelekeni kwamangqamuzana. Uma amangqamuzana ethu ecindezelekile, kungaholela ezinkingeni eziningi zezempilo, okuhlanganisa ukuguga okusheshayo, ukuvuvukala, kanye nengozi eyengeziwe yezifo ezingamahlalakhona njengesifo senhliziyo nemithambo yegazi, isifo sikashukela, nesifo se-neurodegenerative.

I-Mitoquinone, uhlobo olukhethekile lwe-Coenzyme Q10, iye yavela njengethuluzi elinamandla ekulweni nokucindezeleka kwamaselula. Ngokungafani nama-antioxidant endabuko, i-Mitoquinone iklanyelwe ngqo ukukhomba futhi iqongelela ngaphakathi kwe-mitochondria, izikhungo zamandla zamaseli ethu. Lokhu kubalulekile ngoba i-mitochondria isengozini yokulimala kwe-oxidative, futhi ukungasebenzi kwayo kungaba nemiphumela efinyelela kude empilweni yethu. Ngokuletha ukuvikelwa okuhlosiwe kwe-antioxidant ku-mitochondria, i-Mitoquinone isiza ukugcina ukusebenza kwayo okuphelele futhi ibavikele emiphumeleni elimazayo yokucindezeleka.

Njengoba sekushiwo kakade, i-mitochondria yakho idinga amazinga aphezulu e-antioxidant ukugwema ama-radicals mahhala kanye namaprotheni okucindezeleka ekwakheni nokudala umonakalo, kodwa amazinga emvelo omzimba wakho ehla njengoba ukhula.

Ngakho vele uthathe izithako ze-antioxidant? Ngeshwa, ama-antioxidant amaningi kunzima ukuwamunca emathunjini aye egazini futhi makhulu kakhulu ukuwela ulwelwesi lwangaphakathi lwe-mitochondrial, olukhetha kakhulu ukumuncwa kwama-antioxidants.

Ososayensi bethu basemkhankasweni wokunqoba izinselelo zokumuncwa okusebenzayo kwe-antioxidant. Ukuze benze lokhu, bashintsha ukwakheka kwamangqamuzana e-antioxidant CoQ10 (ekhiqizwa ngokwemvelo ku-mitochondria futhi isetshenziselwa ukukhiqiza amandla nokulawula ama-radicals mahhala), iyenze ibe mancane futhi yengeze inkokhiso enhle, iyidonsele ku-mitochondria ekhokhiswa kabi. Uma isifikile, i-Mitoquinone iqala ukulinganisa ngempumelelo ama-radicals mahhala futhi isize ekunciphiseni ukucindezeleka kwamaselula, ukuze amaseli akho (nawe) azizwe esekelwe. Sithanda ukuyicabanga njengobuciko bemvelo.

NgokusekelwaI-Mitoquinone,i-mitochondria yakho, namaseli asebenza ngomthamo ogcwele, okuhlanganisa ngokwemvelo ukukhiqiza ama-molecule abalulekile njenge-NAD ne-ATP, okusiza amangqamuzana alondoloze impilo engcono nobungqabavu namuhla, kusasa, nasesikhathini esizayo.

I-Mitoquinone iqala ukusebenza kusukela lapho ingena kumaseli, yehlisa ukucindezeleka kwamaselula. Izinzuzo zikhula nsuku zonke njengoba amangqamuzana engeziwe evuselelwa kabusha, okuholela empilweni engcono namandla. Nakuba abanye abantu bezobona imiphumela ngaphambi kwesikhathi, ngemva kwezinsuku ezingu-90 amaseli akho azoshajwa ngokugcwele futhi uzofinyelela iphuzu lapho umzimba wakho uzozizwa unamandla, ulinganisele futhi uqabulekile.