Ukuxhumana phakathi kokucindezeleka kwamangqamuzana neMitoquinone, kungani kubalulekile empilweni yakho?

Ezingeni elilula kakhulu, iseli liyisikhwama soketshezi esizungezwe ulwelwesi. Akuzwakali kungavamile, kodwa okumangalisayo ukuthi ngaphakathi kwalolu ketshezi, amanye amakhemikhali nama-organelle enza imisebenzi ekhethekile ehlobene nomsebenzi weseli ngalinye, njengokusiza amangqamuzana e-iris esweni ukulawula ukugeleza kokukhanya.

Okubaluleke kakhulu, amangqamuzana ethu athola namafutha, njengokudla esikudlayo nomoya esiwuphefumulayo, bese ewaguqula abe amandla. Okuhlaba umxhwele ukuthi amangqamuzana angasebenza ngokuzimela, akhiqize amandla awo, futhi aziphindaphinde—eqinisweni, amangqamuzana ayiyunithi encane kakhulu yokuphila engaziphindaphinda. Ngakho-ke, amangqamuzana awakhi nje kuphela izinto eziphilayo; ayizinto eziphilayo ngokwazo.

Amaseli anempilo ayaguga, ayalungisa futhi akhule kahle, akhiqiza amandla anele okusebenza, futhi alawula impendulo yakho yokucindezeleka ukuze agcine umzimba wakho nengqondo yakho isebenza kahle. Ngakho-ke, uwagcina kanjani amaseli akho ephilile ukuqinisekisa ukuthi konke kuhamba kahle?

Ngingawagcina kanjani amangqamuzana ami ephilile?

Njengoba umzimba womuntu wakhiwe cishe ngokuphelele ngamaseli, uma sicabanga ngokuphila "okunempilo", sikhuluma ngokugcina amaseli ephilile. Ngakho-ke imithetho evamile iyasebenza: yidla ukudla okulinganiselayo, gcina amazinga amahle okuzivocavoca, ungabhemi, qiniseka ukuthi ulala ngokwanele nsuku zonke, futhi unciphise ukucindezeleka kokuphila (futhi unciphise isidingo sezimpendulo zokucindezeleka kwamangqamuzana), ukuphuza utshwala, kanye nokuchayeka ebuthi bemvelo. Okuqukethwe yincwadi.

Kodwa kunezinyathelo eziningana ongase ungazazi, futhi yilapho okudingeka sifunde kabanzi ngezwe elimangalisayo lamaseli. Ngoba nsuku zonke, ukucindezeleka kungavela ngaphakathi kwamaseli akho, okungathinta yonke into kusukela emazingeni akho amandla kuya emakhonweni akho okuqonda, indlela oguga ngayo, indlela olulama ngayo ekuzivocavoceni nasekuguleni, kanye nempilo yakho iyonke.

Njengoba sishilo ngaphambili, amangqamuzana akho akhiqiza amandla awo, kodwa yini ngempela edala lawo mandla? Ngaphakathi kwamangqamuzana akho, unezitho ezincane ezibizwa ngokuthi i-mitochondria. Zincane kakhulu, kodwa zinesibopho sokukhiqiza u-90% wamandla omzimba wakho. Lokho kungu-90% wamandla owasebenzisa nsuku zonke, okuhlanganisa nokuzivocavoca ngoMsombuluko, ukukhumbula ukushayela umama ucingo, ukuqala lowo mbiko ka-9 ebusuku obungafuni ukubhala, nokusiza izingane zakho ukuba zilale ngaphandle kokuncibilika. Lapho ingxenye yomzimba wakho idinga amandla amaningi ukuze isebenze (njengenhliziyo yakho, imisipha, noma ubuchopho), kulapho amaseli ayo e-mitochondria eba namandla amaningi okuhlangabezana nalezi zidingo zamandla aphezulu.

Njengokungathi lokho bekunganele, i-mitochondria yakho isiza namaseli akho ukuba akhule, asinde, futhi afe, isize ekukhiqizeni ama-hormone, isize ekugcinweni kwe-calcium ukuze kutholakale izimpawu zamaseli, futhi ibe ne-DNA yayo ehlukile ukuze iwasize enze imisebenzi yawo ekhethekile. Kodwa ngeshwa, lezi yizingxenye ezincane zomzimba wakho lapho izinto zingahamba khona kabi kancane.

Kuyini ukucindezeleka kwamangqamuzana?

Uma i-mitochondria yakho ikhiqiza amandla ukuze usebenze, ikhiqiza nomkhiqizo obizwa ngokuthi ama-free radicals, okufana nokukhishwa kwenjini yemoto. Ama-free radicals awawona wonke amabi, futhi adlala indima ebalulekile, kodwa uma eqoqana ngokweqile, angabangela ukulimala kwamangqamuzana. Lena imbangela eyinhloko yokucindezeleka kwamangqamuzana emzimbeni (ezinye izimbangela zifaka phakathi ukucindezeleka kwemvelo, izifo ezithile, kanye nokulimala ngokomzimba). Uma lokhu sekwenzekile, amangqamuzana akho achitha amandla nesikhathi esiyigugu elwa nomonakalo, noma eqala izimpendulo zokucindezeleka kwamangqamuzana, futhi awakwazi ukwenza wonke umsebenzi obalulekile umzimba wakho odinga ukuba awenze.

Kodwa-ke, i-mitochondria yakho ihlakaniphile – ibizwa ngokuthi yindlu yamandla yeseli ngesizathu esihle! Zizilawula ngokwazo ukuqongelela kwama-free radical ngokukhiqiza ama-antioxidants, aqinisa la ma-free radical aqinile futhi anciphise amathuba okucindezeleka kwamangqamuzana.

I-mitochondria yakho ayithuthuki ngokuguga. Njengoba ukhula, amazinga e-antioxidant omzimba wakho ayancipha ngokwemvelo, okwenza ama-free radicals aphume ekulawuleni. Ngaphezu kwalokho, izimpilo zethu zansuku zonke zisibeka engozini yama-free radical amaningi ngenxa yezinto ezibangela ukucindezeleka njengokungcola, imisebe ye-UV, ukudla okungenampilo, ukuntuleka kokuzilolonga, ukungalali kahle, ukubhema, ukucindezeleka empilweni, kanye nokuphuza utshwala, okwenza kube nzima kakhulu ukulwa nama-free radicals.

Ukucindezeleka kwamangqamuzana kusho ukuthi amangqamuzana akho ayahlaselwa - yilapho "ukuguga nokuphila" kungena khona. Nsuku zonke, amangqamuzana akho asengozini yokulimala ngokulahlekelwa ama-antioxidants ngesikhathi sokuguga kanye neminye imonakalo eyenzeka kuyo yonke "impilo."

Kungani kufanele ukhathazeke ngokucindezeleka kwamangqamuzana?

Lokhu kuhlanganiswa kwezinto ezingaphakathi nezingaphandle kwenza iseli lingakwazi ukubhekana nesimo. Esikhundleni sokusebenza kahle, amangqamuzana ethu acindezeleka kakhulu, okusho ukuthi sihlala sisesimweni sokulwa nomlilo ukuze sigcine imizimba yethu isebenza kahle. Kithina, lokhu kusho ukuzizwa sikhathele kakhulu, sinamandla aphansi ntambama, sinenkinga yokugxila emsebenzini, sizizwa sikhathele ngosuku olulandelayo ngemva kokujima okunzima, silulame kancane ekuguleni, futhi sizizwe noma sibone imiphumela yokuguga igqama kakhulu. Ngamanye amazwi, kuzwakala kabi.

Kunengqondo-ke ukuthi uma amangqamuzana akho esezingeni eliphezulu, nawe uzoba sezingeni eliphezulu. Ama-trillion amangqamuzana emzimbeni wakho akha isisekelo sempilo yakho. Uma amangqamuzana akho ephilile, kuba nomphumela omuhle we-domino, okuhlanganisa nokuvuselela impendulo yakho yokuzivikela yomzimba, esekela impilo yomzimba wakho wonke ukuze uphile impilo yakho ngempela.

I-Mitoquinone isiza kanjani ekulweni nokucindezeleka kwamangqamuzana?

Ukucindezeleka kwamaseli kwenzeka lapho amaseli ethu evezwa yizinto eziphazamisa ukusebenza kwawo okuvamile. Lokhu kungafaka phakathi ukucindezeleka kwe-oxidative, okwenzeka lapho kunokungalingani phakathi kokukhiqizwa kwama-free radical ayingozi kanye nekhono lomzimba lokuwaqeda. Ngaphezu kwalokho, ubuthi bemvelo, ukudla okungekuhle, ngisho nokucindezeleka kwengqondo konke kungafaka isandla ekucindezelekeni kwamaseli. Lapho amaseli ethu ecindezelwe, kungaholela ezinkingeni eziningi zempilo, okuhlanganisa ukuguga okusheshayo, ukuvuvukala, kanye nengozi eyengeziwe yezifo ezingamahlalakhona ezifana nesifo senhliziyo, isifo sikashukela, kanye nezinkinga ze-neurodegenerative.

I-Mitoquinone, uhlobo olukhethekile lwe-Coenzyme Q10, ivele njengethuluzi elinamandla ekulweni nokucindezeleka kwamangqamuzana. Ngokungafani nama-antioxidants endabuko, i-Mitoquinone yenzelwe ngqo ukukhomba nokuqongelela ngaphakathi kwe-mitochondria, amandla amakhulu amaseli ethu. Lokhu kubalulekile ngoba i-mitochondria isengozini enkulu yokulimala kwe-oxidative, futhi ukungasebenzi kahle kwayo kungaba nemiphumela ebanzi empilweni yethu. Ngokuletha isivikelo se-antioxidant esiqondisiwe ku-mitochondria, i-Mitoquinone isiza ukugcina umsebenzi wayo ofanele futhi iwavikele emiphumeleni elimazayo yokucindezeleka.

Njengoba sekufundiwe kakade, i-mitochondria yakho idinga amazinga aphezulu ama-antioxidants ukuze igweme ama-free radical amaningi kanye namaprotheni okucindezeleka ukuthi anganqwabelana futhi abangele umonakalo, kodwa amazinga emvelo omzimba wakho ayancipha njengoba ukhula.

Ngakho-ke thatha nje izithasiselo ze-antioxidant? Ngeshwa, ama-antioxidants amaningi kunzima ukuwamunca kusuka emathunjini aye egazini futhi makhulu kakhulu ukuwela ulwelwesi lwangaphakathi lwe-mitochondrial, olukhetha kakhulu ukumunca ama-antioxidants.

Ososayensi bethu basemsebenzini wokunqoba izinselele zokumuncwa kwe-antioxidant okuphumelelayo. Ukuze benze lokhu, bashintshe isakhiwo sama-molecule se-antioxidant CoQ10 (ekhiqizwa ngokwemvelo kwi-mitochondria futhi esetshenziselwa ukukhiqiza amandla nokulawula ama-free radicals), okwenza ibe ncane futhi yengeze i-positive charge, iyidonsela kwi-negative charge ye-mitochondria. Uma isifikile lapho, i-Mitoquinone iqala ukulinganisela ngempumelelo ama-free radicals futhi isize ekunciphiseni ukucindezeleka kwamangqamuzana, ukuze amaseli akho (nawe) uzizwe usekelwa. Sithanda ukuyicabanga njengomsebenzi wobuciko wemvelo.

Ngokusekelwa yi-I-Mitoquinone,i-mitochondria yakho, namaseli asebenza ngokugcwele, okuhlanganisa nokukhiqiza ama-molecule ayisihluthulelo ngokwemvelo ngendlela ephumelela kakhulu njenge-NAD ne-ATP, okusiza amaseli ukuba alondoloze impilo enhle kanye namandla namuhla, kusasa, nasesikhathini esizayo.

I-Mitoquinone iqala ukusebenza kusukela ngesikhathi imuncwa ngamaseli, inciphisa ukucindezeleka kwamangqamuzana. Izinzuzo ziyanda nsuku zonke njengoba amaseli amaningi evuselelwa, okuholela empilweni engcono kanye namandla. Nakuba abanye abantu bazobona imiphumela kusenesikhathi, ngemva kwezinsuku ezingu-90 amaseli akho azophinde agcwaliswe ngokugcwele futhi uzofinyelela iphuzu lapho umzimba wakho uzozizwa unamandla, ulinganisiwe futhi uvuselelwe.