Ukulwa nokuguga sekuphenduke indatshana embonini yezempilo nempilo enhle, okuheha ukunaka kwabesilisa nabesifazane ngokufanayo. Abantu sebenesithakazelo esikhulu ekulondolozeni ukubukeka kwabo kobusha, njengoba ngokuvamile kuhlotshaniswa nokuzethemba, ukukhanga, kanye nobungqabavu bebonke. Nakuba ukuguga kuyingxenye yemvelo yokuphila, ukuthatha izinyathelo ezisheshayo zokunciphisa inqubo kungaba nezinzuzo ezihlala isikhathi eside.
Ukuguga kuyinto engenakugwenywa futhi eyenzeka yonke indawo yonke into ephilayo ehlangabezana nayo. Pho kungani siguga? Ezihlokweni ezilandelayo, sihlolisisa isayensi yokuguga ukuze sithole izizathu zalesi simo esithakazelisayo nesiyinkimbinkimbi sezinto eziphilayo.
Ukuguga kuyinqubo ye-multifactorial ethonywa izici ezihlukahlukene zofuzo, imvelo kanye nendlela yokuphila. Ayikho impendulo eyodwa yokuthi kungani siguga, kodwa ososayensi baqhamuke nemibono eminingana ezama ukuchaza lesi simo esingokwemvelo. Enye yemibono egqame kakhulu ukunqwabelana komonakalo emazingeni amangqamuzana namangqamuzana. Ngokuhamba kwesikhathi, amangqamuzana ethu nezicubu kuba nengcindezi ye-oxidative, ukulimala kwe-DNA, nezinye izinhlobo zokuguga, okuholela ekwehleni kancane kancane komsebenzi wawo. Le thiyori yaziwa ngokuthi ithiyori "yokugqoka nokudilika" yokuguga.
Enye inkolelo-mbono ithi ukuguga kubangelwa ukufinyezwa kwama-telomere ethu. Ama-telomere angamakepisi avikelayo atholakala ekugcineni kwama-chromosome ethu, futhi adlala indima ebalulekile ekugcineni ukuqina kwe-genome. Kodwa-ke, ngokuhlukana kweseli ngakunye, ama-telomere ethu aba mfushane ngokwemvelo aze afinyelele ubude obubucayi. Kuleli qophelo, amangqamuzana angena esimweni sokululama noma ashone ngokuhlelwa kwamangqamuzana. Eyaziwa ngokuthi "ithiyori ye-telomere yokuguga," lo mbono uphakamisa ukuthi ikhono elilinganiselwe lamaseli ethu lokuphindaphinda lineqhaza enqubweni yokuguga.
Ngemva kokuqonda izimbangela zokuguga, siyazi ukuthi ukuguga kubonakala kuyo yonke into ephilayo futhi akunakuhlehliswa, kodwa kunezici zangaphandle ezingathinta ngokusobala inqubo yokuguga. Ikakhulukazi ukukhetha kwendlela yokuphila njengokuzivocavoca, ukudla kanye nokulawula ingcindezi kungathinta indlela esiguga kahle ngayo. Ukuvivinya umzimba okuvamile kuye kwaboniswa ukuthuthukisa ukuqina kwenhliziyo nemithambo yegazi, ukugcina amandla emisipha, futhi kuthuthukise ukusebenza kwengqondo. Ukudla okunomsoco, okulinganiselayo okucebile kuma-antioxidants kanye nezakhamzimba kungasiza ekunciphiseni ukucindezeleka okwenziwe nge-oxidative futhi kukhuthaze impilo yonke. Ngakolunye uhlangothi, ukuphila okungenampilo nokunganyakazi kungasheshisa inqubo yokuguga futhi kwandise ingozi yezifo ezihlobene nobudala.
Ukuqonda isayensi yokuthi kungani siguga kubalulekile ngoba kunomthelela omkhulu empilweni yethu nasezingeni lempilo. Ucwaningo emkhakheni wokuguga lugqugquzela ukutholwa nokungenelela okuhloselwe ukukhuthaza ukuguga okunempilo. Ososayensi bahlola ngenkuthalo izindlela zokunciphisa noma zokuhlehlisa inqubo yokuguga, ngenhloso yokugcina yokwelula isikhathi sokuphila komuntu kuyilapho begcina ukusebenza komzimba nokuqonda okuphelele.
1. Amajikijolo
Enye yama-antioxidants abalulekile atholakala kuma-blueberries yi-anthocyanin. I-blue blue noma i-purple hue yamajikijolo aluhlaza ngenxa yokuqukethwe kwawo okuphezulu kwe-anthocyanin, okungagcini nje ngokuwanika umbala wawo ogqamile kodwa futhi kusiza ukuvikela isikhumba sethu ezintweni zangaphandle ezibangela ukuguga. Ucwaningo luye lwabonisa ukuthi i-anthocyanins inganciphisa isenzo sama-enzyme aphula i-collagen, iphrotheni ebalulekile ekugcineni ukunwebeka nokuqina kwesikhumba.
Ngaphezu kwezakhiwo zabo ze-antioxidant, ama-blueberries angumthombo omkhulu wamavithamini namaminerali abalulekile asekela impilo yonke namandla. Zinothe ngovithamini C, osiza ekukhiqizeni i-collagen, isekela amasosha omzimba, futhi ivikela emonakalweni wokuchayeka elangeni. Amajikijolo aluhlaza aqukethe namavithamini A no-E, aziwa ngokuvuselela isikhumba.
2. Ihalananda
Inhlanganisela eyinhloko etholakala kumahalananda i-ellagic acid. Le polyphenol enamandla ikhonjiswe ukuthi ivikela isikhumba emisebeni ye-UVA ne-UVB, okuyizimbangela eziyinhloko zokuguga kwesikhumba. I-ellagic acid ayigcini nje ngokusiza ukunciphisa ukubukeka kwemibimbi, futhi ithuthukisa ukunwebeka kwesikhumba ukuze kube nokukhazimula kwentsha.
Ngaphezu kwalokho, amapomegranati aqukethe uvithamini C, osiza ekuhlanganiseni kwe-collagen. I-Collagen iyiphrotheni ebalulekile ehlinzeka ngesakhiwo nokunwebeka esikhumbeni.
Ucwaningo luye lwabonisa ukuthi ukudla ijusi yegromegranate noma okukhishiwe kungase kuvikele ekucindezelekeni kwe-oxidative nokuvuvukala, ngaleyo ndlela kuzuze impilo yonke yesikhumba. Le miphumela ingasiza ekulondolozeni ukubukeka kobusha besikhumba futhi ibambezele inqubo yokuguga kusukela ngaphakathi nangaphandle.
3. Utamatisi
Utamatisi ungumthombo omuhle kakhulu we-lycopene, i-antioxidant enamandla ewenza ube nombala obomvu oyisici. Le antioxidant isiza ukunqanda ama-radicals mahhala ayingozi emzimbeni futhi ivikela isikhumba ekugugeni ngaphambi kwesikhathi okubangelwa izici zemvelo ezinjengokungcola nokuchayeka elangeni.
Utamatisi unothe ngamavithamini A no-C, amavithamini amabili adlala indima ebalulekile ekugcineni isikhumba sinempilo. I-Vitamin A isiza ekukhiqizeni i-collagen, iphrotheni enesibopho sokugcina ukunwebeka nokuqina kwesikhumba. Njengoba sikhula, ukukhiqizwa kwe-collagen ngokwemvelo kuyehla, okuholela emibimbeni nasesikhunjeni esiwohlokayo.
4. I-collagen
I-Collagen iyiphrotheni eyenzeka ngokwemvelo emizimbeni yethu futhi inesibopho sokuhlinzeka amandla nesakhiwo esikhumbeni sethu, amathambo, imisipha kanye nemigqa. Iyisisekelo sesikhumba esibushelelezi, esiqinile futhi esigcwele. Ngeshwa, njengoba sikhula, ukukhiqizwa komzimba wethu kwe-collagen kuncipha, okuholela kulezo zimpawu eziwuhlupho zokuguga.
Imikhiqizo efakwe i-collagen, njengokhilimu, ama-serum, nezithasiselo, ivuselela ukukhiqizwa kwe-collagen ukusiza ukuqinisa nokuvuselela isikhumba. Le mikhiqizo isiza futhi ukubuyisela ukunwebeka kwesikhumba ukuze sibe nebala elincane elikhazimulayo.
5. I-Turmeric
Esinye sezizathu eziyinhloko ukuthi i-turmeric yaziwa ngezinzuzo zayo zokulwa nokuguga ukuthi i-curcumin ehlanganisiwe ye-antioxidant enamandla. I-Curcumin isiza ukunciphisa ama-radicals mahhala, ama-molecule angazinzile abhubhisa amangqamuzana anempilo, okuholela ekugugeni ngaphambi kwesikhathi kanye nesifo esingamahlalakhona.
I-Turmeric nayo inezindawo ezinamandla zokulwa nokuvuvukala. Ukuvuvukala okungapheli kudlala indima ebalulekile ekugugeni, okuholela ekuthuthukisweni kwezifo ezihlukahlukene ezihlobene nobudala. Ngokushintsha izindlela eziyinhloko zokuvuvukala, i-turmeric isiza ukunciphisa ukuvuvukala futhi ibambezele inqubo yokuguga. I-Curcumin iboniswe ukuthuthukisa ukukhiqizwa kwe-collagen, iphrotheni ebalulekile enesibopho sokugcina ukuqina nokuqina kwesikhumba.
1. I-Curcumin: Isimangaliso Segolide
I-Curcumin, i-compound eyinhloko esebenzayo ku-turmeric, iboniswe ukuthi inezici ezinamandla ze-cytoprotective ngenxa yemiphumela yayo enamandla ye-antioxidant. Ucwaningo lwakamuva luye lwabonisa ukuthi linendima ebalulekile enqubweni yokuguga. I-Curcumin yenza kusebenze amaprotheni athile asiza ukubambezela ukuguga kwamangqamuzana futhi andise isikhathi sokuphila I-Curcumin isiza ukulwa nezifo ezihlobene nobudala futhi ibambezele ukuwohloka kokusebenza kwamaselula. Ukwengeza, i-curcumin itholakale inemiphumela emihle empilweni yobuchopho futhi inganciphisa ingozi yezifo ze-neurodeergenerative ezifana ne-Alzheimer's.
2. I-Resveratrol: Iveza izinzuzo zokulwa nokuguga zewayini elibomvu
I-resveratrol, evame ukutholakala esikhumbeni samagilebhisi abomvu, icwaningwe kabanzi ngezindawo zayo zokulwa nokuguga ezingase zibe khona. Ivula iphrotheni ebizwa nge-Sirtuin 1 (SIRT1), ehlotshaniswa nokusebenza okuthuthukisiwe kwamaselula nokuphila isikhathi eside. I-Resveratrol nayo inezindawo zokulwa nokuvuvukala kanye ne-antioxidant, iqhubekisela phambili amandla ayo okulwa nokuguga. Nakuba iwayini elibomvu liqukethe i-resveratrol, akunconywa ukuphuza ngokweqile ngenxa yezingozi zezempilo ezihlobene. Ukwengeza okusesilinganisweni noma ukungeniswa ngemithombo yokudla yemvelo kungase kube nenzuzo enkulu ukukhulula izinzuzo zokulwa nokuguga zalesi sakhi.
3.Urolithin A: Ukusebenzisa amagciwane amathumbu ukulwa nokuguga
I-Urolithin A iyi-metabolite ekhiqizwa amagciwane e-gut avela kumakhompiyutha akhona ezithelweni ezithile njengamahalananda nama-strawberries. Ucwaningo lwakamuva lubonise ukuthi i-urolithin A idlala indima ebalulekile emjikelezweni wengqamuzana futhi kucatshangwa ukuthi iyisikhuthazi esinamandla se-autophagy, iphrotheni ebaluleke kakhulu ekuhlanzeni amangqamuzana alimele futhi ikhuthaze ukuguga okunempilo. inqubo yeselula. Ngokugqugquzela ukuguqulwa kwamaseli, i-Urolithin A inamandla okubambezela ukwehla kwemisipha ehlobene neminyaka futhi ithuthukise impilo yonke nokuphila isikhathi eside.
Isikhathi sokuthumela: Jun-20-2023
