Eminyakeni yamuva, izithasiselo ze-ketone ester zithole ukuthandwa ngezinzuzo zazo zezempilo ezingaba khona. Lezi zithako ziyizinhlobo zokwenziwa zama-ketones, akhiqizwa isibindi kusuka ku-fatty acids ngezikhathi zokuzila ukudla noma ukudla okuphansi kwe-carbohydrate. Izithako ze-Ketone ester kukholakala ukuthi zinezinzuzo eziningi zezempilo, okuhlanganisa amandla anda, ukusebenza kwengqondo okuthuthukisiwe, nokusebenza okuthuthukisiwe kwezemidlalo. Odinga ukukwazi ukuthi kubalulekile ukubonana nochwepheshe bezempilo ngaphambi kokufaka noma yisiphi isithasiselo esisha ohlelweni lwakho lwansuku zonke.
Ama-ketones ayizinhlanganisela eziphilayo ezikhiqizwa isibindi lapho umzimba uphula amafutha ukuze uthole amandla. Zivame ukuhlotshaniswa nokudla okune-carb ephansi noma i-ketogenic, lapho umzimba usesimweni se-ketosis, okusho ukuthi ushisa amafutha ukuze uthole uphethiloli esikhundleni sama-carbohydrates.
Ama-ketone akhiqizwa lapho umzimba ungenayo i-insulin eyanele yokusebenzisa i-glucose ukuze uthole amandla. Lokhu kungase kwenzeke ngezikhathi zokuzila ukudla, ukuvivinya umzimba kanzima, noma ukudla okunama-carbohydrate aphansi. Lapho umzimba ungenayo i-glucose eyanele yamandla, uqala ukuphula amafutha agciniwe futhi uwaguqule abe ama-ketone. Lawa ma-ketone angasetshenziswa ngumzimba nengqondo njengomthombo wamandla ohlukile.
Kunezinhlobo ezintathu eziyinhloko zama-ketones akhiqizwa emzimbeni: i-acetoacetate, i-beta-hydroxybutyrate, ne-acetone. Lawa ma-ketone angama-molecule ancibilikayo emanzini angasetshenziswa njengomthombo wamandla ngemisipha, ubuchopho, nezinye izicubu. Eqinisweni, lapho umzimba uku-ketosis, ubuchopho buyakwazi ukuthola amandla afinyelela ku-75% kuma-ketones.
Ukwengeza, ama-ketones aboniswe ukuthi akhuthaze ukulahlekelwa isisindo ngokucindezela isifiso sokudla nokwandisa ukushiswa kwamafutha. Lesi esinye sezizathu zokuthi kungani ukudla okune-carb ephansi kanye ne-ketogenic kuvame ukuphumelela ekunciphiseni isisindo. Ngokunciphisa inani lama-carbohydrates ekudleni kwakho nokwandisa ukudla kwakho amafutha anempilo namaprotheni, umzimba wakho uyakwazi ukungena esimweni se-ketosis futhi uqale ukushisa amafutha ukuze uthole uphethiloli, okuholela ekwehleni kwesisindo.
Ngakho-ke yini i-ketone esters? I-Ketone esters izithasiselo eziqukethe ama-ketone, okuyizinto eziphilayo ezikhiqizwa lapho umzimba uphula amafutha ukuze uthole amandla. Lezi zinhlanganisela ziyimikhiqizo yemvelo yezinqubo ze-metabolic zomzimba futhi zingakhiqizwa ngokwenziwa. I-Ketone esters ivamise ukuza isesimweni esiwuketshezi futhi ingathathwa ngomlomo.
I-ketone esters ingakusiza kanjani? I-Ketone esters inikeza umzimba umthombo wamandla osheshayo. Lapho umzimba uku-ketosis, uncika kuma-ketone esikhundleni seglucose ukuze uthole uphethiloli. Lokhu kunenzuzo ikakhulukazi kubasubathi kanye nabantu abafuna ukuthuthukisa ukusebenza kwabo ngokomzimba.
Ngaphezu kokunikeza umthombo wamandla osheshayo, olunye ucwaningo lubonisa ukuthi ama-ketones angakwazi ukweqa umgoqo wegazi nobuchopho futhi asetshenziswe njengomthombo wamandla wobuchopho. Lokhu kuye kwavusa isithakazelo emiphumeleni engase ibe khona yokuthuthukisa ingqondo ye-ketone esters.
Ukwengeza, i-ketone esters ingaba nezinzuzo ezingaba khona kubantu ngabanye ekudleni kwe-ketogenic. Ukudla kwe-ketogenic ukudla okunamafutha amaningi, okuphansi kwe-carbohydrate okwenzelwe ukukhuthaza ukukhiqizwa kwama-ketones emzimbeni. Ngokudla i-ketone esters, abantu abadla ukudla kwe-ketogenic bangakwazi ukuqhubeka nokwandisa amazinga e-ketone, okungase kubangele ukushisa okukhulu kwamafutha nokulahlekelwa isisindo.
Okokuqala, kubalulekile ukuqonda ukuthi iyini i-ketone esters. I-Ketone esters iyizithako zokudla ezikhulisa amazinga e-ketone egazini. Ngezikhathi zokudla okuphansi, ukuvinjelwa kwama-carbohydrate, noma ukuvivinya umzimba isikhathi eside, isibindi sikhiqiza ama-ketone avela ku-fatty acid. Lapho umzimba uku-ketosis, uyashintsha ekusebenziseni i-glucose njengomthombo wawo oyinhloko wamandla uye ekusebenziseni ama-ketone. Lesi simo se-metabolic sihlotshaniswa nezinzuzo eziningi zezempilo, kuhlanganise nokuncipha kwesisindo.
Ucwaningo oluningana luphakamisa ukuthi i-ketone esters ingasiza ekunciphiseni isisindo. Ucwaningo olwanyatheliswa kumagazini I-Obesity lwathola ukuthi abahlanganyeli abasebenzisa izithako ze-ketone ester bathola ukuncipha kwesifiso sokudla, okuholela ekunciphiseni kokudla. Olunye ucwaningo ku-Journal of Physiology lubonise ukuthi i-ketone esters ingakhuphula izinga lokugayeka kokudla emzimbeni, okuholela ekushisweni kwamakholori amaningi usuku lonke. Ukwengeza, i-ketone esters iboniswe ukuthuthukisa ukusebenza kokuzivocavoca, okungase kusize ngokuqhubekayo ukulahlekelwa isisindo.
Kodwa kubalulekile ukuqaphela ukuthi i-ketone esters ayisona isisombululo somlingo sokulahlekelwa isisindo. Nakuba bengase babe namandla okusekela imizamo yokulahlekelwa isisindo, abayona indawo yokudla okunempilo nokuvivinya umzimba njalo.
Eminyakeni yamuva nje, i-ketosis iye yazuza ukuthandwa njengendlela yokuthuthukisa ukusebenza kwezemidlalo, ukuthuthukisa ukucaca kwengqondo, nokusiza ukunciphisa umzimba. Abantu abaningi baphendukele kuma-ketones angaphandle kanye ne-ketone esters njengendlela yokufeza i-ketosis futhi bazuze izinzuzo zayo ezingaba khona. Kodwa-ke, abantu bavame ukudideka mayelana nomehluko phakathi kwalezi zithako ezimbili.
Ama-ketone angaphandle empeleni ama-ketones adliwa emithonjeni yangaphandle, njengezithako zokudla. Zingenzeka njengosawoti we-ketone, i-ketone esters, ne-medium chain triglycerides (MCT). Lezi zithako zenzelwe ukukhulisa amazinga e-ketone egazini futhi zinikeze umzimba omunye umthombo wamafutha. I-Ketone esters, ngakolunye uhlangothi, iwuhlobo oluthile lwe-ketone yangaphandle ehlanganiswa ngamakhemikhali, ngokuvamile esesimweni se-liquid.
Omunye umehluko omkhulu phakathi kwe-ketone esters namanye ama-ketones angaphandle ukutholakala kwawo kwe-bioavailability nokuthi akhuphula ngokushesha kangakanani amazinga e-ketone yegazi. I-Ketone esters iyaziwa ngokukhuphula ngokushesha amazinga e-ketone egazi phakathi nemizuzu, okwenza kube yisinqumo esithandwayo kubasubathi kanye nabantu abafuna ukuphakamisa ama-ketone ngokushesha. Ngokuphambene, amanye ama-ketone angaphandle, afana nosawoti we-ketone, angathatha isikhathi eside ukwandisa amazinga e-ketone egazini.
Omunye umehluko obalulekile ukunambitheka nokugaya kwe-ketone esters ngokumelene namanye ama-ketones angaphandle. I-Ketone esters ivame ukuba nokunambitheka okunamandla, okungajabulisi ngenxa yokwakheka kwamakhemikhali futhi kungaba nzima kwabanye abantu ukuyidla. Ngakolunye uhlangothi, ama-ketone salts nama-medium-chain glycerides ngokuvamile anephunga elimnandi futhi kulula ukuwafaka esimisweni sakho sansuku zonke.
Ngokwezindleko, ama-ketone esters ngokuvamile abiza kakhulu kunamanye ama-ketone angaphandle. Ukuhlanganiswa kwe-ketone esters kuyinkimbinkimbi futhi kuyabiza, okuboniswa ngentengo yabo. Ngakolunye uhlangothi, usawoti we-Ketone nama-medium chain glycerides (MCTs), ngokuvamile ashibhile futhi amukeleka kakhudlwana kubathengi. Ucwaningo olwengeziwe luphakamisa ukuthi i-ketone esters ingaba nemiphumela eyingqayizivele ye-metabolic kanye neyokuthuthukisa ukusebenza, ikakhulukazi kubasubathi nakubantu abafuna ukuthuthukisa ukusebenza komzimba.
Okokuqala nokubaluleke kakhulu, kubalulekile ukuqonda ukuthi ayini ama-ketones angaphandle nokuthi ahluke kanjani kuma-ketone akhiqizwa umzimba ngesikhathi se-ketosis. Ama-ketones angaphandle ayimizimba ye-ketone ethathwa njengezithako, imvamisa eyimpuphu noma ifomu lesiphuzo. Lawa ma-ketones angatholakala emithonjeni efana ne-beta-hydroxybutyrate (BHB) usawoti noma ama-esters, angakhuphula amazinga e-ketone yegazi futhi enze isimo se-ketosis ngisho nalapho kungabikho ukuvinjelwa okuqinile kwe-carbohydrate.
1.Thuthukisa ukusebenza ngokomzimba nangokwengqondo. Ucwaningo lubonisa ukuthi ama-ketones angumthombo ohlukile kaphethiloli wobuchopho nemisipha, okwandisa ukukhuthazela, ukuthuthukisa ukusebenza kwengqondo, nokunciphisa umbono womzamo ngesikhathi sokuzivocavoca. Ngokuhlinzeka ngomthombo wamandla osulungile, izithasiselo ze-ketone zangaphandle zingasiza abathanda ukuqina badlule imikhawulo yemizimba yabo futhi bafinyelele ukusebenza okuphezulu.
2.Isiza ekulawuleni isisindo kanye nempilo ye-metabolic. Ngokukhuthaza ukushiswa kwamafutha kanye nokunciphisa isifiso sokudla, ama-ketone angasekela abantu abafuna ukunciphisa umzimba noma ukuthuthukisa ukwakheka komzimba. Ukwengeza, ama-ketones aboniswe ukuthi anomthelela omuhle ekuzweleni kwe-insulin kanye nokulawulwa koshukela wegazi, okungase kuzuze abantu abanezifo ze-metabolic ezifana nokukhuluphala noma uhlobo lwe-2 yesifo sikashukela. Ukufaka izithako ze-ketone zangaphandle ekudleni okuphelele kanye nesimiso sokuzivocavoca kungase kusize ukuthuthukisa ukusebenza kwe-metabolic futhi kukhuthaze impilo yonke.
3.Thuthukisa ukuguqulwa kwe-ketosis. Kulabo abasha ekudleni kwe-ketogenic noma labo abaye baphambuka okwesikhashana ohlelweni lokudla olune-carb ephansi, ama-ketone angaphandle anganikeza indlela esheshayo nephumelelayo yokubuyela ku-ketosis. Lokhu kusiza kakhulu ekunciphiseni ukungakhululeki kanye nezimpawu ze-"keto flu" ezivame ukwenzeka phakathi nezigaba zokuqala zokuvinjelwa kwama-carbohydrate. Ngokusebenzisa amasu ama-exogenous ketone supplements, abantu ngabanye banganciphisa izinselelo zokushintshela esimweni se-ketogenic futhi bavune izinzuzo ze-ketosis ngokushesha okukhulu.
Kubalulekile ukuqaphela ukuthi nakuba izithasiselo ze-ketone zangaphandle zinikeza izinzuzo eziningi ezingase zibe khona, azisona isisombululo somlingo futhi kufanele zisetshenziswe ngokuhambisana nokudla okulinganiselayo kanye nendlela yokuphila enempilo. Ukwengeza, izimpendulo ngazinye kuma-ketones angaphandle zingahluka, ngakho-ke kubalulekile ukulalela umzimba wakho futhi uqaphe ukuthi uzizwa kanjani lapho usebenzisa lezi zithako. Njenganoma yiluphi uhlobo olusha lokudla noma uhlobo lokuqina, kuwukuhlakanipha ukubonana nochwepheshe bezempilo ngaphambi kokwengeza izithasiselo ze-ketone zangaphandle, ikakhulukazi uma unezimo zezokwelapha ezicashile noma okukukhathazayo.
Uma ufuna isithasiselo sekhwalithi ye-ketone ester, kunezici ezimbalwa okufanele uzicabangele. Okokuqala nokubalulekile, kubalulekile ukubheka imikhiqizo yekhwalithi ephezulu ehlolwe ngokuqinile ukuhlanzeka nokusebenza. Ukwengeza, uzophinde ufune ukucabangela ukugcwala kwe-ketone esters ku-supplement, kanye nanoma yiziphi ezinye izithako ezingase zibe nomthelela ekusebenzeni kwayo jikelele.
Enye indlela yokuqinisekisa ukuthi uthola isithasiselo sekhwalithi ye-ketone ester ukwenza ucwaningo lwakho futhi ufunde ukubuyekezwa kwamakhasimende. Bheka imikhiqizo ethole impendulo eyakhayo evela kubasebenzisi, ikakhulukazi mayelana nokusebenza kwayo kanye nezinzuzo ezibalulekile. Kuyasiza futhi ukufuna iseluleko emithonjeni ethembekile njengezingcweti zezempilo nezokuqina ukuze uthole ukuqonda ngezithasiselo ze-ketone ester ezihamba phambili emakethe.
Esinye isici esibalulekile okufanele sicatshangelwe lapho ukhetha isengezo se-ketone ester yifomu ezitholakala ngalo. Ezinye izithasiselo ziza ziwuketshezi, kanti ezinye ziza ziyimpushana noma ziyi-capsule. Ifomu ngalinye linezinzuzo zalo, ngakho-ke kufanelekile ukucabangela ukuthi yiliphi ifomu elifanelana kangcono nezintandokazi zakho kanye nendlela yokuphila.
Intengo nayo iyacatshangelwa lapho ufuna izithasiselo eziphezulu ze-ketone ester. Yize kubalulekile ukutshala imali emikhiqizweni yekhwalithi ephezulu, kubalulekile futhi ukuthola izithasiselo ezihambisana nesabelomali sakho.
I-Suzhou Myland Pharm & Nutrition Inc. ibambe iqhaza ebhizinisini lesengezo sokudla okunempilo kusukela ngo-1992. Yinkampani yokuqala eShayina ukuthuthukisa nokudayisa imbewu yamagilebhisi.
Njengoba inesipiliyoni seminyaka engu-30 futhi iqhutshwa ubuchwepheshe obuphezulu kanye namasu e-R&D athuthukiswe kakhulu, inkampani ithuthukise uhla lwemikhiqizo encintisanayo futhi yaba isithasiselo sesayensi yempilo emisha, ukuhlanganisa ngokwezifiso kanye nenkampani yezinkonzo zokukhiqiza.
Ngaphezu kwalokho, inkampani iphinde ibe ngumkhiqizi obhalisiwe we-FDA, oqinisekisa impilo yabantu ngekhwalithi ezinzile nokukhula okuqhubekayo. Izinsiza ze-R&D zenkampani kanye nezindawo zokukhiqiza kanye namathuluzi okuhlaziya kungokwesimanje futhi anemisebenzi eminingi, futhi ayakwazi ukukhiqiza amakhemikhali esikalini se-milligram kuya kuthani ngokuhambisana namazinga e-ISO 9001 kanye nezinqubo zokukhiqiza ze-GMP.
Umbuzo: Iyini i-ketone ester futhi isebenza kanjani?
A: I-Ketone ester iyisengezo esinikeza umzimba ngama-ketones, akhiqizwa ngokwemvelo yisibindi ngesikhathi sokuzila ukudla noma ukudla okuphansi kwe-carbohydrate. Lapho idliwe, i-ketone ester ingakhuphula ngokushesha amazinga e-ketone egazini, inikeze umzimba omunye umthombo wamafutha ku-glucose.
Q: Ngingayifaka kanjani i-ketone ester esimisweni sami sansuku zonke?
A: I-Ketone ester ingafakwa esimisweni sakho sansuku zonke ngokuyithatha ekuseni njengesengezo sangaphambi kokuzivocavoca, ukuyisebenzisela ukuthuthukisa ukusebenza kwengqondo nokugxila ngesikhathi somsebenzi noma izikhathi zokufunda, noma ukuyidla njengosizo lokubuyisela ngemva kokuzivocavoca. Ingasetshenziswa futhi njengethuluzi lokushintshela ekudleni kwe-ketogenic noma ukuzila ukudla okuphakathi.
Q: Ingabe ikhona imiphumela emibi noma izinyathelo okufanele uzicabangele lapho usebenzisa i-ketone ester?
A: Nakuba i-ketone ester ngokuvamile ibhekwa njengephephile kubantu abaningi, abanye abantu bangase babhekane nokungakhululeki okuncane kwesisu lapho beqala ukuyisebenzisa. Kubalulekile futhi ukubonisana nochwepheshe bezempilo ngaphambi kokufaka i-ketone ester esimisweni sakho, ikakhulukazi uma unezimo zempilo ezicashile noma uthatha imithi.
Q: Ngingayandisa kanjani imiphumela yokusebenzisa i-ketone ester?
A: Ukwandisa imiphumela yokusebenzisa i-ketone ester, kubalulekile ukubhanqa ukusetshenziswa kwayo nendlela yokuphila enempilo ehlanganisa ukuvivinya umzimba okuvamile, ukufakwa kwamanzi okwanele, nokudla okulinganiselayo. Ukwengeza, ukunaka isikhathi sokusetshenziswa kwe-ketone ester ngokuhlobene nemisebenzi yakho nemigomo kungasiza ukwandisa imiphumela yayo.
Umshwana wokuzihlangula: Lesi sihloko esolwazi oluvamile kuphela futhi akufanele sithathwe njengeseluleko sezokwelapha. Olunye ulwazi lokuthunyelwe kwebhulogi luvela ku-inthanethi futhi alusebenzi. Le webhusayithi inomthwalo wemfanelo kuphela wokuhlunga, ukufometha kanye nokuhlela ama-athikili. Injongo yokudlulisa ulwazi olwengeziwe ayisho ukuthi uyavumelana nemibono yayo noma uqinisekise ubuqiniso bokuqukethwe kwayo. Hlala uthintana nochwepheshe bezempilo ngaphambi kokusebenzisa noma yiziphi izithasiselo noma wenze izinguquko ohlelweni lwakho lokunakekelwa kwezempilo.
Isikhathi sokuthumela: Jan-10-2024
