Iqiniso Ngezithako Ze-Magnesium: Okufanele Ukwazi?Nakhu Okufanele Ukwazi

Magnesium iyiminerali ebalulekile kanye ne-cofactor yamakhulu ama-enzyme.

I-Magnesium ihileleke cishe kuzo zonke izinqubo ezinkulu ze-metabolic kanye ne-biochemical ngaphakathi kwamangqamuzana futhi inesibopho semisebenzi eminingi emzimbeni, okuhlanganisa ukuthuthukiswa kwamathambo, umsebenzi we-neuromuscular, izindlela zokubonisa, ukugcinwa kwamandla kanye nokudluliselwa, i-glucose, i-lipid ne-protein metabolism, nokuzinza kwe-DNA ne-RNA. . kanye nokwanda kwamaseli.

I-Magnesium idlala indima ebalulekile ekwakhiweni nasekusebenzeni komzimba womuntu. Kukhona cishe ama-24-29 amagremu we-magnesium emzimbeni omdala.

Cishe i-50% kuya ku-60% ye-magnesium emzimbeni womuntu itholakala emathanjeni, kanti i-34% -39% esele itholakala ezicutshini ezithambile (imisipha nezinye izitho). Okuqukethwe kwe-magnesium egazini kungaphansi kwe-1% yengqikithi yomzimba. I-Magnesium iyindawo yesibili egcwele kakhulu ye-intracellular ngemuva kwe-potassium.

I-Magnesium ibamba iqhaza ekuphenduleni okubalulekile okungaphezu kwama-300 emzimbeni, okufana nalokhu:

Ukukhiqizwa kwamandla

Inqubo yokwenza ama-carbohydrate namafutha ukukhiqiza amandla idinga inani elikhulu lokusabela kwamakhemikhali okuncike ku-magnesium. I-Magnesium iyadingeka ukuze kuhlanganiswe i-adenosine triphosphate (ATP) ku-mitochondria. I-ATP iyi-molecule enikeza amandla cishe kuzo zonke izinqubo ze-metabolic futhi ikhona ngokuyinhloko ngesimo se-magnesium ne-magnesium complexes (MgATP).
ukuhlanganiswa kwama-molecule abalulekile

I-Magnesium iyadingeka ezinyathelweni eziningi ekuhlanganisweni kwe-deoxyribonucleic acid (DNA), i-ribonucleic acid (RNA), namaprotheni. Ama-enzyme amaningana ahilelekile ku-carbohydrate kanye ne-lipid synthesis adinga i-magnesium ukuze isebenze. I-Glutathione iyi-antioxidant ebalulekile ukwakheka kwayo kudinga i-magnesium.

Ukuthutha kwe-ion kuwo wonke ulwelwesi lwamaseli

I-Magnesium iyisici esidingekayo ekuthuthweni okusebenzayo kwama-ion njenge-potassium ne-calcium kuwo wonke ulwelwesi lwamaseli. Ngendima yayo ohlelweni lwezokuthutha lwe-ion, i-magnesium ithinta ukuqhutshwa kwemizwa yezinzwa, ukufinyela kwemisipha kanye nesigqi senhliziyo esivamile.
ukudluliselwa kwesignali yeseli

Ukusayinda amaseli kudinga i-MgATP kumaphrotheni e-phosphorylate futhi kwakhiwe i-molecule ye-cell signaling cyclic adenosine monophosphate (cAMP). I-cAMP ibandakanyeka ezinqubweni eziningi, okuhlanganisa ukukhishwa kwehomoni ye-parathyroid (PTH) kusuka ezindlaleni ze-parathyroid.

ukufuduka kwamaseli

Ukugxila kwe-calcium ne-magnesium emangqamuzaneni oketshezi azungezile kuthonya ukufuduka kwezinhlobo eziningi zamaseli ahlukene. Lo mphumela ekufudukeni kwamaseli ungase ubaluleke ekwelapheni kwesilonda.

Kungani abantu banamuhla ngokuvamile bengenawo i-magnesium?

Abantu banamuhla ngokuvamile banenkinga yokungatholi i-magnesium eyanele kanye nokuntuleka kwe-magnesium.
Izizathu eziyinhloko zihlanganisa:

1. Ukulinywa kwenhlabathi ngokweqile kuholele ekwehleni okukhulu kokuqukethwe kwe-magnesium enhlabathini yamanje, kuphinde kuphazamise okuqukethwe kwe-magnesium ezitshalweni nezilwane ezidla uhlaza. Lokhu kwenza kube nzima kubantu banamuhla ukuthola i-magnesium eyanele ekudleni.
2. Izivundisi zamakhemikhali ezisetshenziswa ngobuningi bezolimo zanamuhla ngokuyinhloko ziyi-nitrogen, i-phosphorus, ne-potassium fertilizer, futhi isithasiselo se-magnesium nezinye izakhi zokulandelela azinakwa.
3. Umanyolo wamakhemikhali kanye nemvula ene-asidi kubangela ukugcwala kwenhlabathi, kunciphisa ukutholakala kwe-magnesium emhlabathini. I-Magnesium enhlabathini ene-asidi igeza kalula futhi ilahleke kalula.
4. Imithi yokubulala ukhula equkethe i-glyphosate isetshenziswa kakhulu. Lesi sithako singabophezela ku-magnesium, okwenza ukuthi i-magnesium emhlabathini iqhubeke yehla futhi iphazamise ukumuncwa kwezakhi ezibalulekile ezifana ne-magnesium izitshalo.
5. Ukudla kwabantu besimanje kunesilinganiso esiphezulu sokudla okucolisisiwe nokugayiwe. Phakathi nenqubo yokudla okucwengiwe nokucutshungulwa, inani elikhulu le-magnesium lizolahleka.
6. I-asidi ephansi ye-gastric ivimbela ukumuncwa kwe-magnesium. I-asidi ephansi yesisu kanye nokungagayeki kahle kungenza kube nzima ukugaya ukudla ngokugcwele futhi kwenze amaminerali kube nzima ukumunca, okuholela ekuntulekeni kwe-magnesium. Uma umzimba womuntu untula i-magnesium, ukugcinwa kwe-asidi yesisu kuzokwehla, kuphinde kuvimbele ukumuncwa kwe-magnesium. Ukuntuleka kwe-Magnesium cishe kungenzeka uma uthatha imithi evimbela ukukhishwa kwe-asidi esiswini.
7. Izithako ezithile zokudla zivimbela ukumuncwa kwe-magnesium.
Isibonelo, ama-tannins etiyeni avame ukubizwa ngokuthi ama-tannins noma i-tannic acid. I-Tannin inekhono eliqinile lokuhlafuna insimbi futhi ingakha izakhiwo ezingancibiliki ngamaminerali ahlukahlukene (njenge-magnesium, insimbi, i-calcium ne-zinc), okuthinta ukumuncwa kwalawa mamineral. Ukusetshenziswa isikhathi eside kwetiye elikhulu elinokuqukethwe okuphezulu kwe-tannin, njengetiye elimnyama netiye eliluhlaza, kungaholela ekuntulekeni kwe-magnesium. Lapho itiye linamandla futhi libaba kakhulu, liyanda okuqukethwe kwe-tannin.
I-oxalic acid esipinashi, isithombo sebhitrudi nokunye ukudla izokwakha inhlanganisela ye-magnesium namanye amaminerali angancibiliki kalula emanzini, okwenza lezi zinto zikhishwe emzimbeni futhi zingakwazi ukumuncwa umzimba.
Ukucwilisa le mifino kungasusa iningi le-oxalic acid. Ngaphezu kwesipinashi namabhitrudi, ukudla okune-oxalate ephezulu kuhlanganisa nalokhu: amantongomane nembewu enjengama-alimondi, ama-cashews, nembewu yesesame; imifino efana ne-kale, i-okra, amaliki, nopelepele; imifino efana nobhontshisi obomvu nobhontshisi omnyama; okusanhlamvu okufana nokunye okufana nokolweni nerayisi elinsundu; cocoa Pink kanye ushokoledi omnyama njll.
I-Phytic acid, etholakala kakhulu ezinhlamvini zezitshalo, ikwazi kangcono ukuhlangana namaminerali afana ne-magnesium, i-iron, ne-zinc ukuze yenze izinhlanganisela ezingancibiliki emanzini, ezibe sezikhishwa emzimbeni. Ukungenisa inani elikhulu lokudla okune-phytic acid kuzophinde kuvimbele ukumuncwa kwe-magnesium futhi kubangele ukulahleka kwe-magnesium.
Ukudla okune-phytic acid eningi kuhlanganisa: ukolweni (ikakhulukazi ukolweni), irayisi (ikakhulukazi irayisi elinsundu), i-oats, ibhali nezinye izinhlamvu; ubhontshisi, uphizi, ubhontshisi omnyama, ubhontshisi wesoya nezinye izilimo eziyizigaxa; ama-alimondi, imbewu yesesame, imbewu kabhekilanga, imbewu yethanga njll. Amantongomane nembewu njll.
8. Izinqubo zanamuhla zokwelashwa kwamanzi zisusa amaminerali, kuhlanganise ne-magnesium, emanzini, okuholela ekunciphiseni ukungena kwe-magnesium ngamanzi okuphuza.
9. Amazinga okucindezeleka ngokweqile empilweni yesimanje azoholela ekwandeni kokusetshenziswa kwe-magnesium emzimbeni.
10. Ukujuluka ngokweqile ngesikhathi sokuzivocavoca kungaholela ekulahlekelweni kwe-magnesium. Izithako ze-diuretic ezifana notshwala ne-caffeine zizosheshisa ukulahleka kwe-magnesium.
Yiziphi izinkinga zempilo ezingase zidale ukushoda kwe-magnesium?

1. I-acid reflux.
I-Spasm yenzeka lapho kuhlangana khona i-esophageal sphincter engezansi kanye nesisu, okungase kubangele ukukhululeka kwe-sphincter, kubangele i-acid reflux futhi kubangele isilungulela. I-Magnesium ingakhulula ama-spasms we-esophageal.

2. Ukungasebenzi kahle kobuchopho njenge-Alzheimer's syndrome.
Ucwaningo luye lwathola ukuthi amazinga e-magnesium ku-plasma kanye noketshezi lwe-cerebrospinal ezigulini ezine-Alzheimer's syndrome aphansi kunabantu abavamile. Amazinga e-magnesium aphansi angase ahlotshaniswe nokuncipha kwengqondo kanye nobukhulu be-Alzheimer's syndrome.
I-Magnesium inemiphumela ye-neuroprotective futhi inganciphisa ukucindezelwa kwe-oxidative kanye nezimpendulo zokuvuvukala kuma-neurons. Omunye wemisebenzi ebalulekile ye-magnesium ion ebuchosheni ukubamba iqhaza ku-synaptic plasticity kanye ne-neurotransmission, okubalulekile ekukhumbuleni nasekufundeni izinqubo. I-Magnesium supplementation ingathuthukisa i-synaptic plasticity futhi ithuthukise ukusebenza kwengqondo nenkumbulo.
I-Magnesium ine-antioxidant ne-anti-inflammatory effects futhi inganciphisa ukucindezeleka kwe-oxidative nokuvuvukala ebuchosheni be-Alzheimer's syndrome, okuyizici ezibalulekile enqubweni ye-pathological ye-Alzheimer's syndrome.

3. Ukukhathala kwe-adrenal, ukukhathazeka, nokwethuka.
Ukucindezela okuphezulu kwesikhathi eside nokukhathazeka kuvame ukuholela ekukhathaleni kwe-adrenal, okudla inani elikhulu le-magnesium emzimbeni. Ukucindezeleka kungabangela umuntu ukuba akhiphe i-magnesium emchameni, okubangela ukuntuleka kwe-magnesium. I-Magnesium ithulisa izinzwa, iphumuza imisipha, futhi ibambezela ukushaya kwenhliziyo, isiza ukunciphisa ukukhathazeka nokwethuka.

4. Izinkinga zenhliziyo nemithambo yegazi njengomfutho wegazi ophakeme, i-arrhythmia, i-coronary artery sclerosis/i-calcium deposition, njll.
Ukuntuleka kwe-Magnesium kungase kuhlotshaniswe nokuthuthukiswa kanye nokuwohloka komfutho wegazi ophezulu. I-Magnesium isiza ukukhulula imithambo yegazi nokunciphisa umfutho wegazi. Ukushoda kweMagnesium kubangela ukuthi imithambo yegazi iqine, okwandisa umfutho wegazi. I-magnesium enganele ingaphazamisa ibhalansi ye-sodium ne-potassium futhi yandise ingozi yomfutho wegazi ophezulu.
Ukuntuleka kwe-Magnesium kuhlobene eduze ne-arrhythmias (njenge-atrial fibrillation, ukushaya ngaphambi kwesikhathi). I-Magnesium idlala indima ebalulekile ekugcineni umsebenzi ojwayelekile kagesi wemisipha yenhliziyo nesigqi. I-Magnesium iqinisa umsebenzi kagesi wamaseli we-myocardial. Ukuntuleka kwe-Magnesium kuholela ekusebenzeni okungavamile kagesi kwamangqamuzana e-myocardial futhi kwandisa ingozi ye-arrhythmia. I-Magnesium ibalulekile ekulawuleni isiteshi se-calcium, futhi ukushoda kwe-magnesium kungase kubangele ukungena kwe-calcium ngokweqile kumaseli emisipha yenhliziyo futhi kwandise ukusebenza kukagesi okungavamile.
Amazinga aphansi e-magnesium ahlotshaniswa nokuthuthukiswa kwesifo se-coronary artery. I-Magnesium isiza ukuvimbela ukuqina kwemithambo yegazi futhi ivikele impilo yenhliziyo. Ukuntuleka kwe-Magnesium kukhuthaza ukwakheka nokuqhubekela phambili kwe-atherosclerosis futhi kwandisa ingozi ye-coronary artery stenosis. I-Magnesium isiza ukugcina ukusebenza kwe-endothelial, futhi ukuntuleka kwe-magnesium kungaholela ekungasebenzi kahle kwe-endothelial futhi kwandise ingozi ye-coronary artery disease.
Ukwakhiwa kwe-atherosclerosis kuhlobene eduze nempendulo yokuvuvukala okungapheli. I-Magnesium inezici zokulwa nokuvuvukala, inciphisa ukuvuvukala ezindongeni ze-artery futhi ivimbele ukwakheka kwama-plaque. Amazinga e-magnesium aphansi ahlotshaniswa nezimpawu zokuvuvukala eziphakeme emzimbeni (njenge-C-reactive protein (CRP)), futhi lezi zimpawu zokuvuvukala zihlobene eduze nokwenzeka nokuqhubeka kwe-atherosclerosis.
Ukucindezeleka kwe-oxidative kuyindlela ebalulekile ye-pathological ye-atherosclerosis. I-Magnesium inezakhiwo ze-antioxidant ezinciphisa ama-radicals mahhala futhi zinciphise ukulimala kwengcindezi ye-oxidative ezindongeni ze-arterial. Ucwaningo luye lwathola ukuthi i-magnesium inganciphisa i-oxidation ye-low-density lipoprotein (LDL) ngokuvimbela ukucindezeleka okwenziwe nge-oxidative, ngaleyo ndlela yehlise ingozi ye-atherosclerosis.
I-Magnesium ibandakanyeka ku-lipid metabolism futhi isiza ekugcineni amazinga e-lipid egazi enempilo. Ukuntuleka kwe-Magnesium kungase kuholele ku-dyslipidemia, okuhlanganisa amazinga aphezulu e-cholesterol namazinga e-triglyceride, okuyizici eziyingozi ze-atherosclerosis. Ukwengezwa kwe-Magnesium kunganciphisa kakhulu amazinga e-triglyceride, ngaleyo ndlela kunciphise ingozi ye-atherosclerosis.
I-coronary arteriosclerosis ivame ukuhambisana nokufakwa kwe-calcium odongeni lwe-artery, into ebizwa ngokuthi i-arterial calcification. Ukubalwa kubangela ukuqina nokuncipha kwemithambo, okuthinta ukugeleza kwegazi. I-Magnesium inciphisa ukwenzeka kokubala kwe-arterial ngokuncintisana ngokuvimbela ukufakwa kwe-calcium kumaseli emisipha abushelelezi emithambo.
I-Magnesium ingalawula iziteshi ze-calcium ion futhi inciphise ukungena ngokweqile kwama-ion e-calcium emangqamuzaneni, ngaleyo ndlela ivimbele ukufakwa kwe-calcium. I-Magnesium iphinde isize ekuncibilikiseni i-calcium futhi iqondise ukusetshenziswa kahle komzimba kwe-calcium, ivumele i-calcium ukuba ibuyele emathanjeni futhi ithuthukise impilo yamathambo kunokuba iyifake emithanjeni. Ukulingana phakathi kwe-calcium ne-magnesium kubalulekile ukuvimbela i-calcium deposits ezicutshini ezithambile.

5. I-arthritis ebangelwa ukufakwa kwe-calcium ngokweqile.
Izinkinga ezifana ne-calcific tendonitis, i-calcific bursitis, i-pseudogout, ne-osteoarthritis zihlobene nokuvuvukala nobuhlungu obubangelwa ukufakwa kwe-calcium ngokweqile.
I-Magnesium ingalawula i-calcium metabolism futhi inciphise ukufakwa kwe-calcium ku-cartilage kanye nezicubu ze-periarticular. I-Magnesium inemiphumela eqeda ukuvuvukala futhi inganciphisa ukuvuvukala nobuhlungu obubangelwa ukufakwa kwe-calcium.

6. Isifuba somoya.
Abantu abanesifuba somoya bavame ukuba namazinga aphansi e-magnesium egazini kunabantu abavamile, futhi amazinga aphansi e-magnesium ahlotshaniswa nokuqina kwesifuba somoya. Ukwengezwa kwe-Magnesium kungakhuphula amazinga e-magnesium egazini kubantu abane-asthma, kuthuthukise izimpawu ze-asthma futhi kunciphise imvamisa yokuhlaselwa.
I-Magnesium isiza ukukhulula imisipha ebushelelezi yemigudu yokuphefumula futhi ivimbele i-bronchospasm, ebaluleke kakhulu kubantu abanesifuba somoya. I-Magnesium inomphumela wokulwa nokuvuvukala, onganciphisa ukusabela kokuvuvukala kwe-airways, ukunciphisa ukungena kwamangqamuzana okuvuvukala emigwaqweni yomoya kanye nokukhululwa kwabaxhumanisi abavuthayo, futhi kuthuthukise izimpawu ze-asthma.
I-Magnesium idlala indima ebalulekile ekulawuleni amasosha omzimba, icindezela ukusabela okweqile kwamasosha omzimba kanye nokunciphisa ukungezwani komzimba nesifuba somoya.

7. Izifo zamathumbu.
Ukuqunjelwa: Ukuntuleka kwe-Magnesium kunganciphisa ukuhamba kwamathumbu futhi kubangele ukuqunjelwa. I-Magnesium iyi-laxative yemvelo. Ukwengeza i-magnesium kungakhuthaza i-peristalsis yamathumbu futhi kuthambise indle ngokumunca amanzi ukuze kusize ukuzikhulula.
I-Irritable Bowel Syndrome (IBS): Abantu abane-IBS bavame ukuba namazinga aphansi e-magnesium. Ukwengeza i-magnesium kungadambisa izimpawu ze-IBS ezinjengobuhlungu besisu, ukuqunjelwa, nokuqunjelwa.
Abantu abanesifo samathumbu esivuthayo (IBD), okuhlanganisa nesifo sikaCrohn kanye nesifo sofuba esiswini, bavame ukuba namazinga aphansi e-magnesium, mhlawumbe ngenxa ye-malabsorption kanye nesifo sohudo esingapheli. Imiphumela elwa nokuvuvukala ye-Magnesium ingasiza ukunciphisa impendulo yokuvuvukala ku-IBD futhi ithuthukise impilo yamathumbu.
Ukukhula kwebhaktheriya emathunjini amancane (SIBO): Abantu abane-SIBO bangase babe ne-magnesium malabsorption ngoba ukukhula kwebhaktheriya ngokweqile kuthinta ukumuncwa kwezakhi. Ukwengezwa kwe-magnesium okufanele kungathuthukisa izimpawu zokuqunjelwa kanye nobuhlungu besisu obuhambisana ne-SIBO.

8. Ukugaya amazinyo.
Ukugaya amazinyo ngokuvamile kwenzeka ebusuku futhi kungenzeka ngezizathu ezihlukahlukene. Lokhu kuhlanganisa ukucindezeleka, ukukhathazeka, ukuphazamiseka kokulala, ukulunywa kabi, nemiphumela engemihle yemithi ethile. Eminyakeni yamuva nje, ucwaningo luye lwabonisa ukuthi ukushoda kwe-magnesium kungase kuhlotshaniswe nokugaya amazinyo, futhi ukufakwa kwe-magnesium kungase kube usizo ekudambiseni izimpawu zokugaya amazinyo.
I-Magnesium idlala indima ebalulekile ekuqhubekiseni izinzwa nasekuphumuzeni imisipha. Ukuntuleka kwe-Magnesium kungase kubangele ukungezwani kwemisipha kanye nama-spasms, okwandisa ingozi yokugedla kwamazinyo. I-Magnesium ilawula isimiso sezinzwa futhi ingasiza ekunciphiseni ukucindezeleka nokukhathazeka, okuyizinto ezivame ukubangela ukugedla kwamazinyo.
Ukwengezwa kweMagnesium kungasiza ekunciphiseni ukucindezeleka nokukhathazeka, okungase kunciphise ukugedla kwamazinyo okubangelwa yilezi zici ezingokwengqondo. I-Magnesium isiza imisipha ukuba ikhululeke futhi inciphise ukugogeka kwemisipha yasebusuku, okungase kunciphise ukwenzeka kokugedla kwamazinyo. I-Magnesium ingakhuthaza ukuphumula futhi ithuthukise izinga lokulala ngokulawula umsebenzi wama-neurotransmitters afana ne-GABA.

9. Amatshe ezinso.
Izinhlobo eziningi zamatshe ezinso yi-calcium phosphate namatshe e-calcium oxalate. Izici ezilandelayo zidala amatshe ezinso:
① Ukwenyuka kwe-calcium emchameni. Uma ukudla kuqukethe inani elikhulu likashukela, i-fructose, utshwala, ikhofi, njll., lokhu kudla okune-acidic kuzokhipha i-calcium emathanjeni ukuze kunciphise i-asidi futhi isetshenziswe ezinso. Ukudla kakhulu i-calcium noma ukusetshenziswa kwezithako ezengeziwe ze-calcium nakho kuzokwandisa okuqukethwe kwe-calcium emchameni.
②I-oxalic acid emchameni iphezulu kakhulu. Uma udla kakhulu ukudla okune-oxalic acid eningi, i-oxalic acid kulokhu kudla izohlangana ne-calcium ukuze kwakheke i-calcium oxalate engenakuncibilika, engaholela ematsheni ezinso.
③Ukuphelelwa amanzi emzimbeni. Ibangela ukugcwala kwe-calcium namanye amaminerali emchameni.
④Ukudla okune-phosphorus ephezulu. Ukudla ukudla okune-phosphorus (okufana neziphuzo ze-carbonated), noma i-hyperparathyroidism, kuzokwandisa amazinga e-phosphoric acid emzimbeni. I-Phosphoric acid izokhipha i-calcium emathanjeni futhi ivumele i-calcium ukuba ifakwe ezinso, yakhe amatshe e-calcium phosphate.
I-Magnesium ingahlangana ne-oxalic acid yakhe i-magnesium oxalate, ene-solubility ephakeme kune-calcium oxalate, enganciphisa ngempumelelo imvula kanye ne-crystallization ye-calcium oxalate futhi inciphise ingozi yamatshe ezinso.
I-Magnesium isiza ukuncibilika kwe-calcium, igcine i-calcium incibilike egazini futhi ivimbele ukwakheka kwamakristalu aqinile. Uma umzimba ungenayo i-magnesium eyanele futhi une-calcium eyeqile, izinhlobo ezihlukahlukene zokubala zingase zenzeke, okuhlanganisa amatshe, ukugoqa kwemisipha, ukuvuvukala kwe-fibrous, i-arterial calcification (i-atherosclerosis), ukubalwa kwezicubu zebele, njll.

10.Parkinson.
Isifo sikaParkinson ngokuyinhloko sibangelwa ukulahlekelwa yi-dopaminergic neurons ebuchosheni, okuholela ekwehleni kwamazinga e-dopamine. Ibangela ukulawulwa kokunyakaza okungavamile, okuholela ekundindizeleni, ukuqina, i-bradykinesia, nokungaqini kwe-postural.
Ukuntuleka kwe-Magnesium kungase kuholele ekungasebenzi kahle kwe-neuronal nokufa, okwandisa ingozi yezifo ze-neurodeergenerative, kuhlanganise nesifo sika-Parkinson. I-Magnesium inemiphumela ye-neuroprotective, ingazinzisa ulwelwesi lwamangqamuzana ezinzwa, ilawule iziteshi ze-calcium ion, futhi yehlise injabulo ye-neuron nokulimala kwamaseli.
I-Magnesium iyi-cofactor ebalulekile ohlelweni lwe-enzyme ye-antioxidant, esiza ukunciphisa ukucindezeleka okwenziwe nge-oxidative kanye nezimpendulo zokuvuvukala. Abantu abanesifo sikaParkinson bavame ukuba namazinga aphezulu okucindezeleka okwenziwe nge-oxidative nokuvuvukala, okusheshisa ukulimala kwe-neuronal.
Isici esiyinhloko sesifo sikaParkinson ukulahlekelwa yi-dopaminergic neurons ku-substantia nigra. I-Magnesium ingase ivikele lawa ma-neurons ngokunciphisa i-neurotoxicity futhi ikhuthaze ukusinda kwezinzwa.
I-Magnesium isiza ukugcina ukusebenza okuvamile kokuqhutshwa kwezinzwa nokufinyela kwemisipha, futhi ikhulula izimpawu zezimoto ezifana nokundindizela, ukuqina kanye ne-bradykinesia ezigulini ezine-Parkinson's disease.

11. Ukucindezeleka, ukukhathazeka, ukucasuka kanye nezinye izifo zengqondo.
I-Magnesium iyisilawuli esibalulekile sama-neurotransmitters amaningana (isb, i-serotonin, i-GABA) edlala indima ebalulekile ekulawulweni kwemizwelo nasekulawuleni ukukhathazeka. Ucwaningo lubonisa ukuthi i-magnesium ingakhuphula amazinga e-serotonin, i-neurotransmitter ebalulekile ehambisana nokulinganisela ngokomzwelo kanye nemizwa yenhlalakahle.
I-Magnesium ingavimbela ukusebenza ngokweqile kwama-NMDA receptors. I-Hyperactivation ye-NMDA receptors ihlotshaniswa nokwanda kwe-neurotoxicity kanye nezimpawu zokucindezeleka.
I-Magnesium inezindawo zokulwa nokuvuvukala kanye ne-antioxidant ezinganciphisa ukuvuvukala nokucindezeleka okwenziwe nge-oxidative emzimbeni, kokubili okuhlotshaniswa nokucindezeleka nokukhathazeka.
I-axis ye-HPA idlala indima ebalulekile ekuphenduleni ingcindezi kanye nokulawulwa kwemizwelo. I-Magnesium ingadambisa ingcindezi nokukhathazeka ngokulawula i-axis ye-HPA futhi yehlise ukukhululwa kwamahomoni okucindezeleka njenge-cortisol.

12. Ukukhathala.
Ukuntuleka kwe-Magnesium kungaholela ekukhathaleni nasezinkingeni ze-metabolic, ikakhulukazi ngoba i-magnesium idlala indima ebalulekile ekukhiqizeni amandla kanye nezinqubo ze-metabolic. I-Magnesium isiza umzimba ukuthi ugcine amazinga ajwayelekile wamandla kanye nemisebenzi ye-metabolic ngokuzinzisa i-ATP, isebenze ama-enzyme ahlukahlukene, inciphise ukucindezeleka kwe-oxidative, nokugcina ukusebenza kwezinzwa nemisipha. Ukwengeza i-magnesium kungathuthukisa lezi zimpawu futhi kuthuthukise amandla nempilo jikelele.
I-Magnesium iyi-cofactor yama-enzyme amaningi, ikakhulukazi ezinqubweni zokukhiqiza amandla. Idlala indima ebalulekile ekukhiqizeni i-adenosine triphosphate (ATP). I-ATP ingumthwali omkhulu wamandla wamaseli, futhi ama-ion e-magnesium abalulekile ekuzinzeni nasekusebenzeni kwe-ATP.
Njengoba i-magnesium ibalulekile ekukhiqizweni kwe-ATP, ukushoda kwe-magnesium kungaholela ekukhiqizweni kwe-ATP enganele, okuholela ekunciphiseni kokunikezwa kwamandla kumaseli, okubonakala njengokukhathala okuvamile.
I-Magnesium ibamba iqhaza ezinqubweni ze-metabolic ezifana ne-glycolysis, umjikelezo we-tricarboxylic acid (umjikelezo we-TCA), kanye ne-oxidative phosphorylation. Lezi zinqubo ziyizindlela eziyinhloko zamaseli okukhiqiza i-ATP. I-molecule ye-ATP kumele ihlanganiswe nama-ion e-magnesium ukuze igcine isimo sayo esisebenzayo (Mg-ATP). Ngaphandle kwe-magnesium, i-ATP ayikwazi ukusebenza kahle.
I-Magnesium isebenza njenge-cofactor yama-enzyme amaningi, ikakhulukazi lawo ahilelekile kumetabolism yamandla, njenge-hexokinase, i-pyruvate kinase, ne-adenosine triphosphate synthetase. Ukuntuleka kwe-Magnesium kubangela ukwehla komsebenzi walawa ma-enzyme, okuthinta ukukhiqizwa nokusetshenziswa kwengqamuzana amandla.
I-Magnesium inemiphumela ye-antioxidant futhi inganciphisa ukucindezeleka okwenziwe nge-oxidative emzimbeni. Ukushoda kwe-Magnesium kukhulisa amazinga engcindezi ye-oxidative, okuholela ekulimaleni kwamaseli nokukhathala.
I-Magnesium ibalulekile ekuqhubekiseni izinzwa kanye nokufinyela kwemisipha. Ukuntuleka kwe-Magnesium kungaholela ekungasebenzi kahle kwezinzwa nemisipha, kuqhubekisele phambili ukukhathala.

13. Isifo sikashukela, ukumelana ne-insulin nezinye izifo ze-metabolic.
I-Magnesium iyingxenye ebalulekile yokusayina kwe-insulin receptor futhi ibandakanyeka ekukhiqizweni nasesenzweni se-insulin. Ukushoda kwe-Magnesium kungaholela ekwehleni kokuzwela kwe-insulin receptor futhi kwandise nengozi yokumelana ne-insulin. Ukuntuleka kwe-Magnesium kuhlotshaniswa nokwanda kwezigameko zokumelana ne-insulin kanye nesifo sikashukela sohlobo 2.
I-Magnesium ibandakanyeka ekusebenzeni kwama-enzyme ahlukahlukene adlala indima ebalulekile ku-glucose metabolism. Ukuntuleka kwe-Magnesium kuthinta i-glycolysis kanye nokusetshenziswa kwe-glucose-mediated insulin. Ucwaningo luthole ukuthi ukushoda kwe-magnesium kungadala ukuphazamiseka kwe-glucose metabolism, kukhuphule amazinga kashukela egazini kanye ne-glycated hemoglobin (HbA1c).
I-Magnesium inemiphumela ye-antioxidant ne-anti-inflammatory futhi inganciphisa ukucindezeleka okwenziwe nge-oxidative kanye nezimpendulo zokuvuvukala emzimbeni, okuyizinqubo ezibalulekile ze-pathological zesifo sikashukela kanye nokumelana ne-insulin. Isimo se-magnesium ephansi sandisa izimpawu zokucindezeleka kwe-oxidative nokuvuvukala, ngaleyo ndlela kukhuthaze ukuthuthukiswa kokumelana ne-insulin nesifo sikashukela.
Ukwengezwa kwe-Magnesium kwandisa ukuzwela kwe-insulin receptor futhi kuthuthukisa ukumuncwa kwe-glucose elawulwa yi-insulin. Ukwengezwa kwe-Magnesium kungathuthukisa imetabolism ye-glucose futhi kunciphise ukuzila kweglucose yegazi kanye namazinga e-glycated hemoglobin ngezindlela eziningi. I-Magnesium ingase yehlise ingozi ye-metabolic syndrome ngokwenza ngcono ukuzwela kwe-insulin, ukwehlisa umfutho wegazi, ukwehlisa i-lipid engavamile, nokunciphisa ukuvuvukala.

14. Ikhanda elibuhlungu kanye nemigraines.
I-Magnesium idlala indima ebalulekile ekukhululweni kwe-neurotransmitter kanye nokulawulwa komsebenzi we-vascular. Ukushoda kwe-Magnesium kungase kuholele ekungalinganisweni kwe-neurotransmitter kanye ne-vasospasm, okungase kubangele ikhanda elibuhlungu kanye nemigraines.
Amazinga aphansi e-magnesium ahlotshaniswa nokuvuvukala okwandayo kanye nokucindezeleka okwenziwe nge-oxidative, okungase kubangele noma kubi nakakhulu i-migraines. I-Magnesium inemiphumela elwa nokuvuvukala kanye ne-antioxidant, inciphisa ukuvuvukala nokucindezeleka okwenziwe nge-oxidative.
I-Magnesium isiza ukukhulula imithambo yegazi, yehlise i-vasospasm, futhi ithuthukise ukugeleza kwegazi, ngaleyo ndlela ikhulule i-migraines.

15. Izinkinga zokulala njengokuqwasha, izinga lokulala eliphansi, ukuphazamiseka kwesigqi se-circadian, nokuvuka kalula.
Imiphumela yokulawula ye-Magnesium ohlelweni lwezinzwa isiza ukukhuthaza ukuphumula nokuzola, futhi ukufakwa kwe-magnesium kungathuthukisa kakhulu ubunzima bokulala ezigulini ezinokuqwasha futhi kusize ukwandisa isikhathi sokulala ngokuphelele.
I-Magnesium ikhuthaza ukulala okujulile futhi ithuthukisa izinga lokulala jikelele ngokulawula umsebenzi wama-neurotransmitters afana ne-GABA.
I-Magnesium idlala indima ebalulekile ekulawuleni iwashi lebhayoloji yomzimba. I-Magnesium ingasiza ekubuyiseleni isigqi esivamile se-circadian ngokuthinta ukugcinwa kwe-melatonin.
Umphumela wokulalisa we-magnesium unganciphisa inani lokuvuka ebusuku futhi ukhuthaze ukulala okuqhubekayo.

16. Ukuvuvukala.
I-calcium eningi ingaholela kalula ekuvuvukeni, kuyilapho i-magnesium ingavimbela ukuvuvukala.
I-Magnesium iyisici esibalulekile ekusebenzeni okuvamile kwamasosha omzimba. Ukuntuleka kwe-Magnesium kungaholela ekusebenzeni okungavamile kwamangqamuzana omzimba futhi kwandise izimpendulo zokuvuvukala.
Ukuntuleka kwe-Magnesium kuholela emazingeni aphakeme okucindezeleka okwenziwe nge-oxidative futhi kwandisa ukukhiqizwa kwama-radicals mahhala emzimbeni, okungase kubangele futhi kubhebhethekise ukuvuvukala. Njenge-antioxidant yemvelo, i-magnesium inganciphisa ama-radicals mahhala emzimbeni futhi inciphise ukucindezeleka okwenziwe nge-oxidative kanye nokusabela kokuvuvukala. Ukwengezwa kwe-Magnesium kunganciphisa kakhulu amazinga omaka bengcindezi ye-oxidative futhi kunciphise ukuvuvukala okuhlobene ne-oxidative.
I-Magnesium inemiphumela elwa nokuvuvukala ngokusebenzisa izindlela eziningi, okuhlanganisa ukuvimbela ukukhululwa kwama-cytokines ane-pro-inflammatory kanye nokunciphisa ukukhiqizwa kwabaxhumanisi abavuthayo. I-Magnesium ingavimbela amazinga ezinto ezibangela ukuvuvukala njenge-tumor necrosis factor-α (TNF-α), i-interleukin-6 (IL-6), ne-C-reactive protein (CRP).

17. I-Osteoporosis.
Ukuntuleka kwe-Magnesium kungaholela ekunciphiseni ukuminyana kwamathambo namandla amathambo. I-Magnesium iyingxenye ebalulekile yenqubo ye-bone mineralization futhi ihileleke ngokuqondile ekwakhekeni kwe-bone matrix. I-magnesium enganele ingaholela ekwehleni kwekhwalithi ye-bone matrix, okwenza amathambo abe sengozini yokulimala.
Ukuntuleka kwe-Magnesium kungaholela emvuthweni we-calcium ngokweqile emathanjeni, futhi i-magnesium idlala indima ebalulekile ekulawuleni ibhalansi ye-calcium emzimbeni. I-Magnesium ikhuthaza ukumuncwa kanye nokusetshenziswa kwe-calcium ngokwenza kusebenze uvithamini D, futhi futhi ilawula i-calcium metabolism ngokuthinta ukukhiqizwa kwehomoni ye-parathyroid (PTH). Ukuntuleka kwe-Magnesium kungaholela ekusebenzeni okungavamile kwe-PTH novithamini D, ngaleyo ndlela kubangele ukuphazamiseka kwe-calcium metabolism futhi kwandise ingozi yokuphuma kwe-calcium emathanjeni.
I-Magnesium isiza ukuvimbela ukufakwa kwe-calcium ezicutshini ezithambile futhi igcine ukugcinwa okufanele kwe-calcium emathanjeni. Uma i-magnesium ishoda, i-calcium ilahleka kalula emathanjeni futhi ifakwe ezicutshini ezithambile.

20. Ukuqina kwemisipha namajaqamba, ubuthakathaka bemisipha, ukukhathala, ukundindizela okungavamile kwemisipha (ukunyakazisa ijwabu leso, ukuluma ulimi, njll.), ubuhlungu obungapheli bemisipha nezinye izinkinga zemisipha.
I-Magnesium idlala indima ebalulekile ekuqhubekiseni izinzwa nokufinyela kwemisipha. Ukuntuleka kwe-Magnesium kungabangela ukuqhutshwa kwezinzwa okungavamile kanye nokwanda kokuthakazelisa kwamangqamuzana emisipha, okuholela emisipha yemisipha kanye namajaqamba. Ukwengeza i-magnesium kungabuyisela ukusebenza okujwayelekile kwezinzwa nokusebenza kokufinyela kwemisipha futhi kunciphise ukujabula ngokweqile kwamangqamuzana emisipha, ngaleyo ndlela kunciphise ama-spasms namajaqamba.
I-Magnesium ibandakanyeka kumetabolism yamandla kanye nokukhiqizwa kwe-ATP (umthombo wamandla oyinhloko weseli). Ukuntuleka kwe-Magnesium kungaholela ekunciphiseni ukukhiqizwa kwe-ATP, okuthinta ukufinyela kwemisipha nokusebenza, okuholela ebuthakathakeni bemisipha nokukhathala. Ukushoda kwe-Magnesium kungaholela ekwenyukeni kokukhathala kanye nokuncipha komthamo wokuzivocavoca ngemuva kokuzivocavoca. Ngokubamba iqhaza ekukhiqizeni i-ATP, i-magnesium inikeza amandla okwanele, ithuthukisa umsebenzi wokunciphisa imisipha, ithuthukise amandla emisipha, futhi inciphise ukukhathala. Ukwengeza i-magnesium kungathuthukisa ukukhuthazela kokuzivocavoca nokusebenza kwemisipha futhi kunciphise ukukhathala kwangemva kokuzivocavoca.
Umphumela wokulawula we-Magnesium ohlelweni lwezinzwa ungathinta ukufinyela kwemisipha ngokuzithandela. Ukuntuleka kwe-Magnesium kungabangela ukungasebenzi kahle kwesimiso sezinzwa, kubangele ukundindizela kwemisipha kanye nesifo semilenze engaphumuli (RLS). Imiphumela yokulalisa ye-magnesium inganciphisa ukujabula ngokweqile kwesistimu yezinzwa, ikhulule izimpawu ze-RLS, futhi ithuthukise ikhwalithi yokulala.
I-Magnesium inezindawo zokulwa nokuvuvukala kanye ne-antioxidant, inciphisa ukuvuvukala nokucindezeleka okwenziwe nge-oxidative emzimbeni. Lezi zici zihlotshaniswa nobuhlungu obungapheli. I-Magnesium ihilelekile ekulawuleni ama-neurotransmitters amaningi, njenge-glutamate ne-GABA, edlala indima ebalulekile ekuboneni ubuhlungu. Ukuntuleka kwe-Magnesium kungase kuholele ekulawuleni ubuhlungu obungavamile kanye nokwanda kokubona ubuhlungu. Ukwengezwa kwe-Magnesium kungase kunciphise izimpawu zobuhlungu obungapheli ngokulawula amazinga e-neurotransmitter.

21.Ukulimala nokululama kwezemidlalo.
I-Magnesium idlala indima ebalulekile ekuqhubeni kwemizwa kanye nokufinyela kwemisipha. Ukushoda kwe-Magnesium kungase kubangele ukweqisa kwemisipha kanye nokufinyela okungenakuzikhethela, okwandisa ingozi yama-spasms namajaqamba. Ukwengeza i-magnesium kungalawula ukusebenza kwemizwa nemisipha futhi kunciphise ukuqina kwemisipha namajaqamba ngemva kokuzivocavoca.
I-Magnesium iyingxenye eyinhloko ye-ATP (umthombo wamandla oyinhloko wengqamuzana) futhi ihileleke ekukhiqizeni amandla kanye ne-metabolism. Ukuntuleka kwe-Magnesium kungaholela ekukhiqizweni kwamandla anganele, ukwanda kokukhathala, nokunciphisa ukusebenza kwezemidlalo. I-Magnesium supplementation ingathuthukisa ukukhuthazela kokuzivocavoca futhi inciphise ukukhathala ngemva kokuzivocavoca.
I-Magnesium inezinto ezilwa nokuvuvukala ezinganciphisa ukusabela kokuvuvukala okubangelwa ukuzivocavoca futhi kusheshise ukubuyiswa kwemisipha nezicubu.
I-Lactic acid iyi-metabolite ekhiqizwa ngesikhathi se-glycolysis futhi ikhiqizwa ngamanani amakhulu ngesikhathi sokuzivocavoca kanzima. I-Magnesium iyi-cofactor yama-enzyme amaningi ahlobene ne-energy metabolism (njenge-hexokinase, i-pyruvate kinase), edlala indima ebalulekile ku-glycolysis kanye ne-lactate metabolism. I-Magnesium isiza ukusheshisa ukucaciswa nokuguqulwa kwe-lactic acid futhi inciphisa ukuqoqwa kwe-lactic acid.

 

Ungahlola kanjani uma untula ku-magnesium?

Uma sikhuluma iqiniso, ukuzama ukuthola izinga langempela le-magnesium emzimbeni wakho ngokusebenzisa izinto ezijwayelekile zokuhlola empeleni kuyinkinga enzima kakhulu.

Kukhona cishe amagremu angu-24-29 e-magnesium emzimbeni wethu, cishe i-2/3 yayo emathanjeni kanye ne-1/3 kumaseli ahlukahlukene kanye nezicubu. I-magnesium esegazini ibala kuphela cishe i-1% yenani eliphelele le-magnesium emzimbeni (kuhlanganise ne-serum engu-0.3% kuma-erythrocyte kanye no-0.5% kumaseli abomvu egazi).
Njengamanje, ezibhedlela eziningi e-China, ukuhlolwa okujwayelekile kokuqukethwe kwe-magnesium kuvame ukuba "ukuhlolwa kwe-serum magnesium". Ibanga elijwayelekile lalokhu kuhlolwa liphakathi kuka-0.75 no-0.95 mmol/L.

Kodwa-ke, ngenxa yokuthi i-magnesium ye-serum ibala kuphela ngaphansi kuka-1% wengqikithi yokuqukethwe kwe-magnesium emzimbeni, ayikwazi ukukhombisa ngokweqiniso nangokunembile okuqukethwe kwangempela kwe-magnesium ezicutshini namaseli ahlukahlukene omzimba.

Okuqukethwe kwe-magnesium ku-serum kubaluleke kakhulu emzimbeni futhi kuyinto ehamba phambili yokuqala. Ngoba i-magnesium ye-serum kufanele igcinwe ekugxilweni okuphumelelayo ukuze kugcinwe imisebenzi ethile ebalulekile, njengokushaya kwenhliziyo okuphumelelayo.

Ngakho-ke lapho ukudla kwakho kwe-magnesium kuqhubeka nokuntula, noma umzimba wakho ubhekene nesifo noma ukucindezeleka, umzimba wakho uzoqala ukukhipha i-magnesium kumathishu noma amangqamuzana afana nemisipha bese uyihambisa egazini ukuze usize ukugcina amazinga ajwayelekile e-serum magnesium.

Ngakho-ke, lapho inani lakho le-magnesium ku-serum libonakala lingaphakathi kwebanga elijwayelekile, i-magnesium ingase iqedwe kwezinye izicubu namaseli omzimba.

Futhi uma uhlola futhi uthola ukuthi ngisho ne-serum magnesium iphansi, isibonelo, ngaphansi kwebanga elivamile, noma eduze nomkhawulo ophansi webanga elivamile, kusho ukuthi umzimba usuvele usesimweni sokuntuleka okukhulu kwe-magnesium.

I-red blood cell (RBC) ileveli ye-magnesium kanye nokuhlolwa kwezinga le-platelet magnesium kunembe kakhulu kunokuhlolwa kwe-serum magnesium. Kodwa namanje ayikameli ngempela amazinga eqiniso e-magnesium emzimbeni.

Ngenxa yokuthi awekho amangqamuzana egazi abomvu noma ama-platelet ane-nuclei ne-mitochondria, i-mitochondria iyingxenye ebaluleke kakhulu yokugcina i-magnesium. Ama-platelet abonisa ngokunembile kakhulu izinguquko zakamuva kumazinga e-magnesium kunamaseli abomvu egazi ngoba ama-platelet aphila izinsuku ezingu-8-9 kuphela uma kuqhathaniswa nezinsuku ezingu-100-120 zamaseli abomvu egazi.

Ukuhlola okunembe kakhudlwana yilezi: okuqukethwe kwe-magnesium ye-muscle biopsy, i-sublingual epithelial cell content magnesium.
Kodwa-ke, ngaphezu kwe-serum magnesium, izibhedlela zasekhaya njengamanje zingenza okuncane kakhulu kwezinye izivivinyo ze-magnesium.
Yingakho uhlelo lwezokwelapha lwendabuko sekuyisikhathi eside lungakunaki ukubaluleka kwe-magnesium, ngoba ukumane ukwahlulela ukuthi isiguli sishoda yini ku-magnesium ngokulinganisa amanani e-serum magnesium ngokuvamile kuholela ekwahluleleni okungalungile.
Ukwahlulela cishe izinga le-magnesium yesiguli kuphela ngokulinganisa i-serum magnesium kuyinkinga enkulu ekuxilongweni nasekwelashweni kwamanje.

Ungakhetha kanjani isithako esilungile se-magnesium?

Kunezinhlobo ezingaphezu kweshumi nambili ezahlukene zezithako ze-magnesium emakethe, njenge-magnesium oxide, i-magnesium sulfate, i-magnesium chloride, i-magnesium citrate, i-magnesium glycinate, i-magnesium threonate, i-magnesium taurate, njll.
Nakuba izinhlobo ezahlukene zezithako ze-magnesium zingathuthukisa inkinga yokuntuleka kwe-magnesium, ngenxa yokuhluka kwesakhiwo samangqamuzana, amazinga okumuncwa ahluka kakhulu, futhi anezici zawo kanye nokusebenza kahle.
Ngakho-ke, kubaluleke kakhulu ukukhetha isengezo se-magnesium esifanelana nawe futhi sixazulula izinkinga ezithile.

Ungafunda ngokucophelela okuqukethwe okulandelayo, bese ukhetha uhlobo lwesithasiselo se-magnesium esikufanelekela kakhulu ngokuya ngezidingo zakho kanye nezinkinga ofuna ukugxila ekuzixazululeni.

Izithako ze-Magnesium azinconywa

i-magnesium oxide

Inzuzo ye-magnesium oxide ukuthi inokuqukethwe okuphezulu kwe-magnesium, okungukuthi, igremu ngalinye le-magnesium oxide linganikeza ama-ion amaningi e-magnesium kunezinye izithako ze-magnesium ngezindleko eziphansi.

Kodwa-ke, lesi yisithasiselo se-magnesium esinezinga eliphansi kakhulu lokumunca, cishe ngo-4% kuphela, okusho ukuthi iningi le-magnesium alikwazi ukumuncwa ngempela futhi lisetshenziswe.

Ngaphezu kwalokho, i-magnesium oxide inomphumela obalulekile we-laxative futhi ingasetshenziswa ukwelapha ukuqunjelwa.

Ithambisa indle ngokumunca amanzi emathunjini, ithuthukise i-peristalsis yamathumbu, futhi isiza ukukhululeka. Imithamo ephezulu ye-magnesium oxide ingase ibangele ukuphazamiseka kwamathumbu, okuhlanganisa isifo sohudo, ubuhlungu besisu, namajaqamba esiswini. Abantu abanokuzwela kwe-gastrointestinal kufanele basebenzise ngokuqapha.

I-Magnesium sulfate

Izinga lokumuncwa kwe-magnesium sulfate nalo liphansi kakhulu, ngakho iningi le-magnesium sulfate ethathwe ngomlomo ayikwazi ukumuncwa futhi izokhishwa nendle esikhundleni sokungena egazini.

I-Magnesium sulfate nayo inomphumela obalulekile we-laxative, futhi umphumela wayo we-laxative uvame ukuvela phakathi kwemizuzu engama-30 kuya kwamahora angu-6. Lokhu kungenxa yokuthi ama-ion e-magnesium angamuncwa amunca amanzi emathunjini, akhuphule umthamo wokuqukethwe kwamathumbu, futhi akhuthaze ukuthunjwa.
Kodwa-ke, ngenxa yokuncibilika kwayo okuphezulu emanzini, i-magnesium sulfate ivame ukusetshenziswa ngomjovo we-intravenous ezimeni eziphuthumayo esibhedlela ukwelapha i-acute hypomagnesemia, i-eclampsia, ukuhlasela okunamandla kwesifuba somoya, njll.

Kungenjalo, i-magnesium sulfate ingasetshenziswa njengosawoti wokugeza (owaziwa nangokuthi ama-Epsom salts), amuncwa esikhumbeni ukuze akhulule ubuhlungu bemisipha nokuvuvukala futhi akhuthaze ukukhululeka nokululama.

i-magnesium aspartate

I-Magnesium aspartate iwuhlobo lwe-magnesium olwakhiwe ngokuhlanganisa i-aspartic acid ne-magnesium, okuyisithasiselo se-magnesium esiyimpikiswano.
Inzuzo iwukuthi: I-Magnesium aspartate ine-bioavailability ephezulu, okusho ukuthi ingamuncwa ngokuphumelelayo futhi isetshenziswe umzimba ukukhulisa ngokushesha amazinga e-magnesium egazini.
Ngaphezu kwalokho, i-aspartic acid iyi-amino acid ebalulekile ebandakanyeka kumetabolism yamandla. Idlala indima ebalulekile kumjikelezo we-tricarboxylic acid (umjikelezo we-Krebs) futhi isiza amaseli ukukhiqiza amandla (ATP). Ngakho-ke, i-magnesium aspartate ingasiza ekwandiseni amazinga wamandla futhi inciphise imizwa yokukhathala.
Kodwa-ke, i-aspartic acid iyi-amino acid ejabulisayo, futhi ukudla ngokweqile kungase kubangele ukuvuthwa ngokweqile kwesimiso sezinzwa, kubangele ukukhathazeka, ukuqwasha, noma ezinye izimpawu zemizwa.
Ngenxa yenjabulo ye-aspartate, abantu abathile abazwelayo kuma-amino acids ajabulisayo (njengeziguli ezinezifo ezithile zemizwa) bangase bangafaneleki ukulawulwa kwesikhathi eside noma okuphezulu kwe-magnesium aspartate.

Izithasiselo Ze-Magnesium Ezinconyiwe

I-Magnesium L-Threonate

I-Magnesium threonate yakhiwa ngokuhlanganisa i-magnesium ne-L-threonate. I-Magnesium threonate inezinzuzo ezibalulekile ekuthuthukiseni ukusebenza kwengqondo, ekudambiseni ukukhathazeka nokudangala, ukusiza ukulala, nokuvikela imithambo-luvo ngenxa yezakhiwo zayo zamakhemikhali eziyingqayizivele kanye nokungena okusebenza kahle kakhulu kwesithiyo segazi nobuchopho.

Ingena Kusithiyo Sobuchopho Begazi: I-Magnesium threonate ikhonjiswe ukuthi iphumelela kakhulu ekungeneni umgoqo wegazi nobuchopho, okuwunikeza inzuzo eyingqayizivele ekwandiseni amazinga e-magnesium ebuchosheni. Ucwaningo luye lwabonisa ukuthi i-magnesium threonate ingakhuphula kakhulu ukugxila kwe-magnesium ku-cerebrospinal fluid, ngaleyo ndlela ithuthukise ukusebenza kwengqondo.

Ithuthukisa ukusebenza kwengqondo nenkumbulo: Ngenxa yekhono layo lokukhulisa amazinga e-magnesium ebuchosheni, i-magnesium threonate ingathuthukisa kakhulu ukusebenza kwengqondo nenkumbulo, ikakhulukazi kubantu asebekhulile nalabo abanokukhubazeka kwengqondo. Ucwaningo lubonisa ukuthi i-magnesium threonate supplementation ingathuthukisa kakhulu ikhono lokufunda lobuchopho kanye nokusebenza kwenkumbulo yesikhashana.

Yehlisa Ukukhathazeka Nokucindezeleka: I-Magnesium idlala indima ebalulekile ekuqhubeni kwezinzwa kanye nebhalansi ye-neurotransmitter. I-Magnesium threonate ingasiza ekudambiseni izimpawu zokukhathazeka nokudangala ngokwandisa ngempumelelo amazinga e-magnesium ebuchosheni.
I-Neuroprotection: Abantu abasengozini yezifo ze-neurodeergenerative, njenge-Alzheimer's and Parkinson's disease. I-Magnesium threonate inemiphumela ye-neuroprotective futhi isiza ukuvimbela futhi ibambezele ukuqhubeka kwezifo ze-neurodeergenerative.

I-Magnesium Taurate

I-Magnesium taurine iyinhlanganisela ye-magnesium ne-taurine. Ihlanganisa izinzuzo ze-magnesium ne-taurine futhi iyisengezo esihle kakhulu se-magnesium.
I-bioavailability ephezulu: I-Magnesium taurate ine-bioavailability ephezulu, okusho ukuthi umzimba ungamunca kalula futhi usebenzise lolu hlobo lwe-magnesium.
Ukubekezelelana okuhle kwamathumbu: Ngenxa yokuthi i-magnesium taurate inezinga eliphezulu lokumunca epheshaneni lesisu, ngokuvamile mancane amathuba okuba ibangele ukungakhululeki kwamathumbu.

Isekela impilo yenhliziyo: I-Magnesium ne-taurine zombili zisiza ukulawula ukusebenza kwenhliziyo. I-Magnesium isiza ukugcina isigqi senhliziyo esivamile ngokulawula ukugxila kwe-calcium ion kumaseli emisipha yenhliziyo. I-Taurine ine-antioxidant kanye ne-anti-inflammatory properties, ivikela amangqamuzana enhliziyo ekucindezelekeni kwe-oxidative kanye nokulimala kokuvuvukala. Ucwaningo oluningi selukhombisile ukuthi i-magnesium taurine inezinzuzo ezibalulekile zezempilo yenhliziyo, yehlisa umfutho wegazi ophakeme, yehlisa ukushaya kwenhliziyo okungajwayelekile, futhi ivikela ku-cardiomyopathy.

Impilo Yesistimu Yezinzwa: I-Magnesium ne-taurine zombili zidlala indima ebalulekile ohlelweni lwezinzwa. I-Magnesium iyi-coenzyme ekuhlanganiseni kwama-neurotransmitters ahlukahlukene futhi isiza ekugcineni umsebenzi ojwayelekile wesimiso sezinzwa. I-Taurine ivikela amangqamuzana ezinzwa futhi ikhuthaze impilo ye-neuronal. I-Magnesium taurine ingadambisa izimpawu zokukhathazeka nokudangala futhi ithuthukise umsebenzi wonke wohlelo lwezinzwa. Kubantu abanokukhathazeka, ukucindezeleka, ukucindezeleka okungapheli nezinye izimo zemizwa.

I-Antioxidant ne-anti-inflammatory effects: I-Taurine inemiphumela enamandla ye-antioxidant ne-anti-inflammatory, enganciphisa ukucindezeleka kwe-oxidative kanye nezimpendulo zokuvuvukala emzimbeni. I-Magnesium isiza futhi ekulawuleni amasosha omzimba futhi inciphise ukuvuvukala. Ucwaningo lubonisa ukuthi i-magnesium taurate ingasiza ekuvimbeleni izifo ezihlukahlukene ezingapheli ngokusebenzisa izakhiwo zayo ze-antioxidant ne-anti-inflammatory.

Ithuthukisa impilo ye-metabolic: I-Magnesium idlala indima ebalulekile ekusetshenzisweni kwamandla, ekukhiqizweni kwe-insulin nasekusetshenzisweni kwayo, nasekulawuleni ushukela wegazi. I-Taurine iphinde isize ukuthuthukisa ukuzwela kwe-insulin, isize ukulawula ushukela wegazi, futhi ithuthukise i-metabolic syndrome nezinye izinkinga. Lokhu kwenza i-magnesium taurine isebenze kangcono kunezinye izithasiselo ze-magnesium ekuphathweni kwe-metabolic syndrome kanye nokumelana ne-insulin.

I-Taurine ku-Magnesium Taurate, njenge-amino acid eyingqayizivele, nayo inemiphumela eminingi:

I-Taurine iyi-amino acid engokwemvelo isulfure futhi iyi-amino acid engeyona iphrotheni ngoba ayibandakanyeki ekuhlanganiseni amaprotheni njengamanye ama-amino acid.

Le ngxenye isatshalaliswa kabanzi ezicutshini zezilwane ezihlukahlukene, ikakhulukazi enhliziyweni, ebuchosheni, emehlweni, nasemisipha yamathambo. Itholakala nasekudleni okuhlukahlukene, njengenyama, inhlanzi, imikhiqizo yobisi, neziphuzo ezinikeza amandla.

I-Taurine emzimbeni womuntu ingakhiqizwa ku-cysteine ​​​​ngaphansi kwesenzo se-cysteine ​​​​sulfinic acid decarboxylase (Csad), noma ingatholakala ekudleni futhi imuncwe amaseli ngokusebenzisa abathuthi be-taurine.

Njengoba iminyaka ikhula, ukugcwala kwe-taurine nama-metabolites ayo emzimbeni womuntu kuzokwehla kancane kancane. Uma kuqhathaniswa nabantu abasha, ukugcwala kwe-taurine ku-serum yabantu asebekhulile kuzokwehla ngama-80%.

1. Sekela impilo yenhliziyo nemithambo yegazi:

Ilawula umfutho wegazi: I-Taurine isiza ukwehlisa umfutho wegazi futhi ikhuthaze i-vasodilation ngokulawula ibhalansi ye-sodium, i-potassium ne-calcium ion. I-Taurine inganciphisa kakhulu amazinga omfutho wegazi ezigulini ezinomfutho wegazi ophakeme.

Ivikela inhliziyo: Inemiphumela ye-antioxidant futhi ivikela ama-cardiomyocyte emonakalweni obangelwa ukucindezeleka okwenziwe nge-oxidative. Ukwengezwa kwe-taurine kungathuthukisa ukusebenza kwenhliziyo futhi kunciphise ingozi yesifo senhliziyo.

2. Vikela impilo yesistimu yezinzwa:

I-Neuroprotection: I-Taurine inemiphumela ye-neuroprotective, ivimbela izifo ze-neurodegenerative ngokuzinzisa ulwelwesi lwamangqamuzana nokulawula ukugxila kwe-calcium ion, ukuvimbela ukuvuthwa ngokweqile kwe-neuronal nokufa.

Umphumela wokupholisa: Inemiphumela yokudambisa kanye ne-anxiolytic, isiza ukuthuthukisa isimo sengqondo kanye nokukhulula ukucindezeleka.

3. Ukuvikelwa kombono:

Ukuvikelwa kwe-retina: I-Taurine iyingxenye ebalulekile ye-retina, esiza ukugcina ukusebenza kwe-retina nokuvimbela ukuwohloka kombono.

Umphumela we-Antioxidant: Unganciphisa ukulimala kwama-radicals mahhala kumaseli e-retinal futhi ulibazise ukwehla kombono.

4. Impilo ye-Metabolic:

Ukulawula ushukela wegazi: i-taurine ingasiza ekuthuthukiseni ukuzwela kwe-insulin, ilawule amazinga kashukela egazini, futhi ivikele i-metabolic syndrome.

I-Liposy Metabolism: Isiza ukulawula i-lipid metabolism futhi yehlise izinga le-cholesterol ne-triglyceride egazini.

5. Ukuzivocavoca umzimba:

Ukunciphisa ukukhathala kwemisipha: I-Telonic acid inganciphisa ukucindezeleka kwe-oxidative nokuvuvukala ngesikhathi sokuzivocavoca, ukunciphisa ukukhathala kwemisipha.

Thuthukisa ukukhuthazela: Kungathuthukisa ukufinyela kwemisipha nokukhuthazela, futhi kuthuthukise ukusebenza kokuzivocavoca.