Iqiniso Ngezithasiselo Ze-Magnesium: Okufanele Ukwazi？Nakhu Okufanele Ukwazi

I-Magnesium iyiminerali ebalulekile kanye ne-cofactor yamakhulu ama-enzyme.

I-magnesium ihilelekile cishe kuzo zonke izinqubo ezinkulu ze-metabolic kanye ne-biochemical ngaphakathi kwamaseli futhi inesibopho semisebenzi eminingi emzimbeni, okuhlanganisa ukuthuthukiswa kwamathambo, umsebenzi wezinzwa, izindlela zokubonisana, ukugcinwa kwamandla kanye nokudluliselwa, i-glucose, i-lipid kanye ne-protein metabolism, kanye nokuzinza kwe-DNA kanye ne-RNA kanye nokwanda kwamaseli.

I-magnesium idlala indima ebalulekile ekwakhiweni nasekusebenzeni komzimba womuntu. Kukhona cishe amagremu angu-24-29 e-magnesium emzimbeni womuntu omdala.

Cishe u-50% kuya ku-60% we-magnesium emzimbeni womuntu utholakala emathanjeni, kanti u-34%-39% osele utholakala ezicutshini ezithambile (imisipha nezinye izitho zomzimba). Okuqukethwe kwe-magnesium egazini kungaphansi kuka-1% wokuqukethwe komzimba wonke. I-magnesium iyindawo yesibili etholakala kakhulu ngaphakathi kweseli ngemuva kwe-potassium.

I-Magnesium ibandakanyeka ezindleleni ezibalulekile ezingaphezu kuka-300 zomzimba, njenge:

Ukukhiqizwa kwamandla

Inqubo yokugaya ama-carbohydrate namafutha ukuze kukhiqizwe amandla idinga inani elikhulu lezimpendulo zamakhemikhali ezincike ku-magnesium. I-magnesium iyadingeka ekwakhiweni kwe-adenosine triphosphate (ATP) ku-mitochondria. I-ATP iyi-molecule enikeza amandla cishe kuzo zonke izinqubo ze-metabolic futhi ikhona ikakhulukazi ngesimo se-magnesium kanye ne-magnesium complexes (MgATP).
ukwenziwa kwama-molecule abalulekile

I-magnesium iyadingeka ezinyathelweni eziningi zokwenziwa kwe-deoxyribonucleic acid (DNA), i-ribonucleic acid (RNA), kanye namaprotheni. Ama-enzyme amaningana ahilelekile ekwakhiweni kwama-carbohydrate kanye nama-lipid adinga i-magnesium ukuze isebenze. I-Glutathione iyi-antioxidant ebalulekile ekwakhiweni kwayo kudinga i-magnesium.

Ukuthuthwa kwe-ion kudlule ulwelwesi lweseli

I-magnesium iyisici esidingekayo ekuthuthweni okusebenzayo kwama-ion njenge-potassium ne-calcium kuwo wonke ama-membrane esisele. Ngendima yayo ohlelweni lokuthutha ama-ion, i-magnesium ithinta ukuqhutshwa kwemizwa yezinzwa, ukufinyela kwemisipha kanye nesigqi senhliziyo esivamile.
ukudluliswa kwesignali yeseli

Ukubonisana kwamaseli kudinga i-MgATP ukuze i-phosphorylate amaprotheni futhi yakhe i-molecule yokubonisana kwamaseli i-cyclic adenosine monophosphate (cAMP). I-cAMP ihilelekile ezinqubweni eziningi, okuhlanganisa ukukhishwa kwe-parathyroid hormone (PTH) ezindlaleni ze-parathyroid.

ukufuduka kwamaseli

Ukuhlushwa kwe-calcium ne-magnesium emaselini azungezile kuthinta ukufuduka kwezinhlobo eziningi zamaseli. Lo mphumela ekufudukeni kwamaseli ungabaluleka ekwelapheni amanxeba.

Kungani abantu banamuhla bentula i-magnesium?

Abantu banamuhla bavame ukuhlushwa ukuntuleka kwe-magnesium nokuntuleka kwe-magnesium.
Izizathu eziyinhloko zifaka:

1. Ukulinywa ngokweqile kwenhlabathi kuholele ekwehleni okukhulu kokuqukethwe kwe-magnesium enhlabathini yamanje, okuthena kakhulu okuqukethwe kwe-magnesium ezitshalweni nasezitshalweni ezidla uhlaza. Lokhu kwenza kube nzima kubantu banamuhla ukuthola i-magnesium eyanele ekudleni.
2. Umanyolo wamakhemikhali osetshenziswa ngobuningi kwezolimo zanamuhla ikakhulukazi umanyolo we-nitrogen, i-phosphorus, kanye ne-potassium, kanti i-magnesium nezinye izakhi zokulandelela azinakwa.
3. Umanyolo wamakhemikhali kanye nemvula ene-asidi kubangela ukwakheka kwe-asidi enhlabathini, okunciphisa ukutholakala kwe-magnesium enhlabathini. I-magnesium enhlabathini ene-asidi igezwa kalula futhi ilahleka kalula.
4. Izibulali-zinambuzane eziqukethe i-glyphosate zisetshenziswa kabanzi. Lesi sithako singabopha i-magnesium, okubangela ukuthi i-magnesium enhlabathini yehle kakhulu futhi kuthinte ukumuncwa kwezakhamzimba ezibalulekile njenge-magnesium yizitshalo.
5. Ukudla kwabantu banamuhla kunesilinganiso esikhulu sokudla okucwengiwe nokucutshunguliwe. Ngesikhathi sokudla kucwengiwe futhi kucutshunguliwe, kuzolahleka inani elikhulu le-magnesium.
6. I-asidi ephansi esiswini ivimbela ukumuncwa kwe-magnesium. I-asidi ephansi esiswini kanye nokungagayeki kahle kungenza kube nzima ukugaya ukudla ngokugcwele futhi kwenze kube nzima ukumuncwa kwamaminerali, okuholela ekuntulekeni kwe-magnesium emzimbeni. Uma umzimba womuntu untula i-magnesium, ukukhiqizwa kwe-asidi esiswini kuzoncipha, okuzophazamisa ukumuncwa kwe-magnesium. Ukuntuleka kwe-magnesium kungenzeka kakhulu uma uthatha imithi evimbela ukumuncwa kwe-asidi esiswini.
7. Izithako ezithile zokudla zivimbela ukumuncwa kwe-magnesium.
Isibonelo, ama-tannins etiyeni avame ukubizwa ngokuthi ama-tannins noma i-tannic acid. I-tannin inekhono eliqinile lokuchelela insimbi futhi ingakha ama-complex anganyibiliki anamaminerali ahlukahlukene (njenge-magnesium, i-iron, i-calcium kanye ne-zinc), okuthinta ukumuncwa kwala maminerali. Ukusetshenziswa isikhathi eside kwetiye eliningi elinokuqukethwe okuphezulu kwe-tannin, njengetiye elimnyama netiye eliluhlaza, kungaholela ekusweleni kwe-magnesium. Uma itiye liqinile futhi libaba kakhulu, kulapho okuqukethwe kwe-tannin kukhuphuka khona.
I-oxalic acid esesipinashi, ku-beetroot nakwezinye izinhlobo zokudla izokwakha ama-compounds ane-magnesium kanye namanye amaminerali angancibiliki kalula emanzini, okwenza lezi zinto zikhishwe emzimbeni futhi zingakwazi ukumuncwa ngumzimba.
Ukuhlanza le mifino kungasusa iningi le-oxalic acid. Ngaphezu kwesipinashi nama-beet, ukudla okune-oxalate eningi kufaka phakathi: amantongomane nembewu efana nama-alimondi, ama-cashew, nembewu yesesame; imifino efana ne-kale, i-okra, ama-leek, nopelepele; imidumba efana nobhontshisi obomvu nobhontshisi omnyama; okusanhlamvu okufana ne-buckwheat nelayisi elinsundu; i-cocoa Ushokoledi opinki nomnyama njll.
I-Phytic acid, etholakala kabanzi ezitshalweni zezitshalo, ikwazi ukuhlanganiswa kangcono namaminerali afana ne-magnesium, i-iron, ne-zinc ukuze kwakheke amakhemikhali angancibiliki emanzini, abese ekhishwa emzimbeni. Ukudla inani elikhulu lokudla okune-phytic acid eningi kuzophazamisa ukumuncwa kwe-magnesium futhi kubangele ukulahlekelwa yi-magnesium.
Ukudla okune-phytic acid eningi kufaka phakathi: ukolweni (ikakhulukazi ukolweni ophelele), ilayisi (ikakhulukazi ilayisi elinsundu), i-oats, ibhali kanye nokunye okusanhlamvu; ubhontshisi, ubhontshisi onama-chickpeas, ubhontshisi omnyama, ubhontshisi kanye neminye imifino; ama-alimondi, imbewu yesesame, imbewu yelanga, imbewu yethanga njll. Amantongomane kanye nembewu njll.
8. Izinqubo zanamuhla zokuhlanza amanzi zisusa amaminerali, okuhlanganisa ne-magnesium, emanzini, okuholela ekunciphiseni ukungenisa i-magnesium ngamanzi okuphuza.
9. Amazinga okucindezeleka ngokweqile empilweni yanamuhla azoholela ekusetshenzisweni kwe-magnesium emzimbeni.
10. Ukujuluka ngokweqile ngesikhathi sokuzivocavoca kungaholela ekulahlekelweni yi-magnesium. Izithako zokukhipha isisu ezifana notshwala ne-caffeine zizosheshisa ukulahleka kwe-magnesium.
Yiziphi izinkinga zempilo ezingabangelwa ukuntuleka kwe-magnesium?

1. Ukubuyela kwe-asidi.
Ukuqaqamba kwenzeka lapho kuhlangana khona i-sphincter engezansi komphimbo kanye nesisu, okungabangela ukuthi i-sphincter iphumule, okubangela i-acid reflux futhi kubangele isilungulela. I-magnesium ingaqeda ukuqaqamba komphimbo.

2. Ukungasebenzi kahle kobuchopho njenge-Alzheimer's syndrome.
Izifundo zithole ukuthi amazinga e-magnesium ku-plasma kanye noketshezi lwe-cerebrospinal lweziguli ezine-Alzheimer's syndrome aphansi kunabantu abavamile. Amazinga aphansi e-magnesium angase ahlobane nokwehla kwengqondo kanye nobunzima be-Alzheimer's syndrome.
I-Magnesium inemiphumela yokuvikela imizwa futhi inganciphisa ukucindezeleka kwe-oxidative kanye nezimpendulo zokuvuvukala kuma-neurons. Omunye wemisebenzi ebalulekile yama-ion e-magnesium ebuchosheni ukubamba iqhaza ekuqinisweni kwe-synaptic kanye nokudluliselwa kwemizwa, okubalulekile ezinqubweni zenkumbulo nokufunda. Ukwengezwa kwe-magnesium kungathuthukisa ukuqina kwe-synaptic futhi kuthuthukise ukusebenza kwengqondo kanye nenkumbulo.
I-magnesium inemiphumela yokulwa nokuvuvukala kanye ne-antioxidant futhi inganciphisa ukucindezeleka kwe-oxidative kanye nokuvuvukala ebuchosheni be-Alzheimer's syndrome, okuyizinto ezibalulekile enkambisweni ye-Alzheimer's syndrome.

3. Ukukhathala kwe-adrenal, ukukhathazeka, kanye nokwesaba.
Ukucindezeleka okuphezulu kwesikhathi eside kanye nokukhathazeka kuvame ukuholela ekukhathaleni kwe-adrenal, okudla inani elikhulu le-magnesium emzimbeni. Ukucindezeleka kungabangela umuntu ukuthi akhiphe i-magnesium emchameni, okubangela ukuntuleka kwe-magnesium. I-magnesium ithulisa izinzwa, ikhulule imisipha, futhi yehlise izinga lokushaya kwenhliziyo, isize ekunciphiseni ukukhathazeka nokwesaba.

4. Izinkinga zenhliziyo nemithambo yegazi njengomfutho wegazi ophakeme, i-arrhythmia, i-coronary artery sclerosis/calcium deposition, njll.
Ukuntuleka kwe-magnesium kungase kuhlotshaniswe nokukhula kanye nokuwohloka komfutho wegazi ophakeme. I-magnesium isiza ukukhulula imithambo yegazi kanye nokwehlisa umfutho wegazi. Ukuntuleka kwe-magnesium kubangela ukuthi imithambo yegazi inciphe, okwandisa umfutho wegazi. Ukuntuleka kwe-magnesium enganele kungaphazamisa ibhalansi ye-sodium ne-potassium futhi kwandise ingozi yomfutho wegazi ophakeme.
Ukuntuleka kwe-magnesium kuhlobene kakhulu nokuphazamiseka kwe-rhythmia (njenge-atrial fibrillation, ukushaya kwangaphambi kwesikhathi). I-magnesium idlala indima ebalulekile ekugcineni umsebenzi kagesi wemisipha yenhliziyo ojwayelekile kanye nesigqi. I-magnesium iyisiqiniseko somsebenzi kagesi wamaseli e-myocardial. Ukuntuleka kwe-magnesium kuholela emsebenzini kagesi ongavamile wamaseli e-myocardial futhi kwandisa ingozi ye-arrhythmia. I-magnesium ibalulekile ekulawulweni kwesiteshi se-calcium, futhi ukuntuleka kwe-magnesium kungabangela ukungena kwe-calcium ngokweqile kumaseli emisipha yenhliziyo futhi kwandise umsebenzi kagesi ongavamile.
Amazinga aphansi e-magnesium ahlotshaniswa nokukhula kwesifo semithambo yenhliziyo. I-magnesium isiza ekuvimbeleni ukuqina kwemithambo yegazi futhi ivikele impilo yenhliziyo. Ukuntuleka kwe-magnesium kukhuthaza ukwakheka nokuqhubeka kwe-atherosclerosis futhi kwandisa ingozi ye-stenosis yemithambo yenhliziyo. I-magnesium isiza ekugcineni ukusebenza kwe-endothelial, kanti ukuntuleka kwe-magnesium kungaholela ekungasebenzi kahle kwe-endothelial futhi kwandise ingozi yesifo semithambo yenhliziyo.
Ukwakheka kwe-atherosclerosis kuhlobene kakhulu nokusabela okungapheli kokuvuvukala. I-magnesium inezakhiwo zokulwa nokuvuvukala, inciphisa ukuvuvukala ezindongeni zemithambo yegazi futhi ivimbele ukwakheka kwe-plaque. Amazinga aphansi e-magnesium ahlotshaniswa nezimpawu zokuvuvukala eziphakeme emzimbeni (njenge-C-reactive protein (CRP)), futhi lezi zimpawu zokuvuvukala zihlobene kakhulu nokuvela kanye nokuqhubeka kwe-atherosclerosis.
Ukucindezeleka kwe-oxidative kuyindlela ebalulekile ye-pathological ye-atherosclerosis. I-magnesium inezakhiwo ze-antioxidant eziqeda ama-free radicals futhi zinciphise umonakalo we-oxidative stress ezindongeni zemithambo yegazi. Izifundo zithole ukuthi i-magnesium inganciphisa i-oxidation ye-low-density lipoprotein (LDL) ngokuvimbela ukucindezeleka kwe-oxidative, ngaleyo ndlela inciphise ingozi ye-atherosclerosis.
I-magnesium ibandakanyeka ekugayweni kwamafutha futhi isiza ukugcina amazinga aphilile e-lipid egazini. Ukuntuleka kwe-magnesium kungaholela ekukhuleni kwe-dyslipidemia, okuhlanganisa amazinga aphezulu e-cholesterol kanye ne-triglyceride, okuyizinto ezibangela i-atherosclerosis. Ukwengezwa kwe-magnesium kunganciphisa kakhulu amazinga e-triglyceride, ngaleyo ndlela kuncishiswe ingozi ye-atherosclerosis.
I-coronary arteriosclerosis ivame ukuhambisana nokufakwa kwe-calcium odongeni lwemithambo yegazi, into ebizwa ngokuthi i-arterial calcification. I-Calcification ibangela ukuqina nokuncishiswa kwemithambo yegazi, okuthinta ukugeleza kwegazi. I-Magnesium inciphisa ukwenzeka kwe-arterial calcification ngokuvimbela ngokuncintisana ukufakwa kwe-calcium emangqamuzaneni emisipha ebushelelezi yemithambo yegazi.
I-Magnesium ingalawula iziteshi ze-calcium ion futhi inciphise ukungena ngokweqile kwama-calcium ion emaseli, ngaleyo ndlela ivimbele ukufakwa kwe-calcium. I-Magnesium iyasiza futhi ekuncibilikiseni i-calcium futhi iqondise ukusetshenziswa kahle kwe-calcium emzimbeni, ivumela i-calcium ukuthi ibuyele emathanjeni futhi ikhuthaze impilo yamathambo kunokuba iyifake emithanjeni yegazi. Ibhalansi phakathi kwe-calcium ne-magnesium ibalulekile ukuvimbela ukufakwa kwe-calcium ezicutshini ezithambile.

5. Isifo samathambo esibangelwa ukugcwala ngokweqile kwe-calcium.
Izinkinga ezifana ne-calcific tendonitis, i-calcific bursitis, i-pseudogout, kanye ne-osteoarthritis zihlobene nokuvuvukala nobuhlungu obubangelwa ukugcwala kwe-calcium ngokweqile.
I-Magnesium ingalawula ukusebenza kwe-calcium futhi inciphise ukufakwa kwe-calcium ezicutshini ze-cartilage kanye ne-periarticular. I-Magnesium inemiphumela yokulwa nokuvuvukala futhi inganciphisa ukuvuvukala nobuhlungu obubangelwa ukufakwa kwe-calcium.

6. Isifuba somoya.
Abantu abane-asthma bavame ukuba namazinga aphansi e-magnesium egazini kunabantu abavamile, kanti amazinga aphansi e-magnesium ahlotshaniswa nobunzima be-asthma. Ukwengezwa kwe-magnesium kungakhuphula amazinga e-magnesium egazini kubantu abane-asthma, kuthuthukise izimpawu ze-asthma futhi kunciphise ukuvama kokuhlaselwa.
I-magnesium isiza ekuphumuzeni imisipha ebushelelezi yemigudu yomoya futhi ivimbele i-bronchospasm, ebaluleke kakhulu kubantu abane-asthma. I-magnesium inomphumela wokulwa nokuvuvukala, onganciphisa impendulo yokuvuvukala yemigudu yomoya, unciphise ukungena kwamaseli okuvuvukala emigudwini yomoya kanye nokukhululwa kwezidakamizwa zokuvuvukala, futhi uthuthukise izimpawu ze-asthma.
I-magnesium idlala indima ebalulekile ekulawuleni amasosha omzimba, icindezela izimpendulo eziningi zomzimba futhi inciphise ukusabela kokungezwani komzimba ku-asthma.

7. Izifo zamathumbu.
Ukuqunjelwa: Ukuntuleka kwe-magnesium kunganciphisa ukuhamba kwamathumbu futhi kubangele ukuqunjelwa. I-magnesium iyisihlanzi semvelo. Ukwengeza i-magnesium kungakhuthaza ukujikeleza kwamathumbu futhi kuthambise indle ngokumunca amanzi ukusiza ekukhululeni.
I-Irritable Bowel Syndrome (IBS): Abantu abane-IBS bavame ukuba namazinga aphansi e-magnesium. Ukwengeza i-magnesium kunganciphisa izimpawu ze-IBS ezifana nobuhlungu besisu, ukuqunjelwa, kanye nokuqunjelwa.
Abantu abanesifo samathumbu esivuvukalayo (i-IBD), okuhlanganisa nesifo sikaCrohn kanye nesifo sofuba esibangela ukuvuvukala, bavame ukuba namazinga aphansi e-magnesium, mhlawumbe ngenxa yokungamuncwa kahle kanye nesifo sohudo esingamahlalakhona. Imiphumela yokulwa nokuvuvukala kwe-magnesium ingasiza ekunciphiseni impendulo yokuvuvukala ku-IBD futhi ithuthukise impilo yamathumbu.
Ukukhula ngokweqile kwamagciwane amathumbu amancane (i-SIBO): Abantu abane-SIBO bangase babe nokungamuncwa kahle kwe-magnesium ngoba ukukhula ngokweqile kwamagciwane kuthinta ukumuncwa kwezakhamzimba. Ukwengezwa kwe-magnesium okufanele kungathuthukisa izimpawu zokuqunjelwa kanye nobuhlungu besisu obuhambisana ne-SIBO.

8. Ukugaya amazinyo.
Ukugaya amazinyo kuvame ukwenzeka ebusuku futhi kungenzeka ngezizathu ezahlukahlukene. Lokhu kufaka phakathi ukucindezeleka, ukukhathazeka, izinkinga zokulala, ukulunywa kabi, kanye nemiphumela emibi yemithi ethile. Eminyakeni yamuva nje, izifundo zikhombisile ukuthi ukuntuleka kwe-magnesium kungase kuhlobane nokugaya amazinyo, futhi ukwengezwa kwe-magnesium kungaba usizo ekunciphiseni izimpawu zokugaya amazinyo.
I-magnesium idlala indima ebalulekile ekuqhubeni izinzwa kanye nokuphumula kwemisipha. Ukuntuleka kwe-magnesium kungabangela ukucindezeleka kwemisipha kanye nokuqaqamba, okwandisa ingozi yokugaywa kwamazinyo. I-magnesium ilawula uhlelo lwezinzwa futhi ingasiza ekunciphiseni ukucindezeleka nokukhathazeka, okuyizinto ezivame ukubangela ukugaywa kwamazinyo.
Ukwengezwa kwe-magnesium kungasiza ekunciphiseni amazinga okucindezeleka nokukhathazeka, okungase kunciphise ukugaywa kwamazinyo okubangelwa yilezi zici zengqondo. I-magnesium isiza imisipha ukuba iphumule futhi inciphise ukuqaqamba kwemisipha ebusuku, okungase kunciphise ukwenzeka kokugaywa kwamazinyo. I-magnesium ingakhuthaza ukuphumula futhi ithuthukise ikhwalithi yokulala ngokulawula umsebenzi wama-neurotransmitters njenge-GABA.

9. Amatshe ezinso.
Izinhlobo eziningi zamatshe ezinso yi-calcium phosphate kanye namatshe e-calcium oxalate. Lezi zinto ezilandelayo zibangela amatshe ezinso:
① Ukwanda kwe-calcium emchameni. Uma ukudla kuqukethe ushukela omningi, i-fructose, utshwala, ikhofi, njll., lokhu kudla okune-acid kuzodonsa i-calcium emathanjeni ukuze kunciphise i-acidity futhi kuyigaye ngezinso. Ukudla i-calcium ngokweqile noma ukusebenzisa izithasiselo ezengeziwe ze-calcium kuzokwandisa nokuqukethwe kwe-calcium emchameni.
②I-oxalic acid emchameni iphezulu kakhulu. Uma udla ukudla okuningi okune-oxalic acid, i-oxalic acid kulokhu kudla izohlangana ne-calcium ukuze yakhe i-calcium oxalate enganyibiliki, okungaholela ematsheni ezinso.
③Ukuphelelwa amanzi emzimbeni. Kubangela ukwanda kwamazinga e-calcium namanye amaminerali emchameni.
④Ukudla okune-phosphorus eningi. Ukudla ukudla okuningi okuqukethe i-phosphorus (njengeziphuzo ezine-carbonated), noma i-hyperparathyroidism, kuzokhulisa amazinga e-phosphoric acid emzimbeni. I-phosphoric acid izodonsa i-calcium emathanjeni futhi ivumele i-calcium ukuthi ibekwe ezinso, yakhe amatshe e-calcium phosphate.
I-magnesium ingahlangana ne-oxalic acid ukuze yakhe i-magnesium oxalate, enokuncibilika okuphezulu kune-calcium oxalate, enganciphisa ngempumelelo imvula kanye nokwakheka kwe-calcium oxalate futhi inciphise ingozi yamatshe ezinso.
I-magnesium isiza i-calcium ukuthi incibilike, igcine i-calcium incibilike egazini futhi ivimbele ukwakheka kwamakristalu aqinile. Uma umzimba untula i-magnesium eyanele futhi une-calcium eningi, kungenzeka kube nezinhlobo ezahlukene ze-calcium, okuhlanganisa amatshe, ukuqaqamba kwemisipha, ukuvuvukala kwe-fibrous, i-arterial calcification (atherosclerosis), i-breast tissue calcification, njll.

10. I-Parkinson.
Isifo sikaParkinson sibangelwa kakhulu ukulahleka kwama-neuron e-dopaminergic ebuchosheni, okuholela ekwehleni kwamazinga e-dopamine. Sibangela ukulawulwa okungavamile kokunyakaza, okuholela ekuthuthumeleni, ukuqina, i-bradykinesia, kanye nokungazinzi kwesimo somzimba.
Ukuntuleka kwe-magnesium kungaholela ekungasebenzi kahle kwe-neuron kanye nokufa, okwandisa ingozi yezifo eziwohlokayo ze-neuro, okuhlanganisa nesifo sikaParkinson. I-magnesium inemiphumela yokuvikela i-neuron, ingazinzisa ulwelwesi lwamaseli ezinzwa, ilawule iziteshi ze-calcium ion, futhi inciphise ukushaqeka kwama-neuron kanye nomonakalo wamaseli.
I-Magnesium iyi-cofactor ebalulekile ohlelweni lwe-enzyme ye-antioxidant, esiza ekunciphiseni ukucindezeleka kwe-oxidative kanye nezimpendulo zokuvuvukala. Abantu abanesifo sikaParkinson bavame ukuba namazinga aphezulu okucindezeleka kwe-oxidative kanye nokuvuvukala, okusheshisa umonakalo wezinzwa.
Isici esiyinhloko sesifo sikaParkinson ukulahleka kwama-neuron e-dopaminergic ku-substantia nigra. I-magnesium ingavikela la ma-neuron ngokunciphisa ubuthi be-neuron nokukhuthaza ukusinda kwama-neuron.
I-magnesium isiza ukugcina ukusebenza okuvamile kokuhanjiswa kwemizwa kanye nokufinyela kwemisipha, futhi iqeda izimpawu zokunyakaza njengokuthuthumela, ukuqina kanye ne-bradykinesia ezigulini ezinesifo sikaParkinson.

11. Ukucindezeleka, ukukhathazeka, ukucasuka kanye nezinye izifo zengqondo.
I-Magnesium iwumlawuli obalulekile wama-neurotransmitter amaningana (isib. i-serotonin, i-GABA) adlala indima ebalulekile ekulawuleni imizwa kanye nokulawula ukukhathazeka. Ucwaningo lubonisa ukuthi i-magnesium ingakhuphula amazinga e-serotonin, i-neurotransmitter ebalulekile ehlotshaniswa nokulinganisela ngokomzwelo kanye nemizwa yenhlalakahle.
I-magnesium ingavimbela ukusebenza ngokweqile kwama-receptor e-NMDA. Ukusebenza ngokweqile kwama-receptor e-NMDA kuhlotshaniswa nokwanda kobuthi be-neurological kanye nezimpawu zokucindezeleka.
I-Magnesium inezakhiwo zokulwa nokuvuvukala kanye ne-antioxidant ezinganciphisa ukuvuvukala kanye nokucindezeleka kwe-oxidative emzimbeni, kokubili okuhlobene nokucindezeleka nokukhathazeka.
I-axis ye-HPA idlala indima ebalulekile ekuphenduleni ukucindezeleka kanye nokulawula imizwa. I-magnesium inganciphisa ukucindezeleka nokukhathazeka ngokulawula i-axis ye-HPA kanye nokunciphisa ukukhishwa kwama-hormone okucindezeleka njenge-cortisol.

12. Ukukhathala.
Ukuntuleka kwe-magnesium kungaholela ekukhathaleni nasezinkingeni ze-metabolic, ikakhulukazi ngoba i-magnesium idlala indima ebalulekile ekukhiqizweni kwamandla kanye nezinqubo ze-metabolic. I-magnesium isiza umzimba ukuthi ugcine amazinga ajwayelekile wamandla kanye nemisebenzi ye-metabolic ngokuzinzisa i-ATP, isebenze ama-enzyme ahlukahlukene, inciphise ukucindezeleka kwe-oxidative, kanye nokugcina ukusebenza kwezinzwa nemisipha. Ukwengeza i-magnesium kungathuthukisa lezi zimpawu futhi kuthuthukise amandla kanye nempilo iyonke.
I-Magnesium iyi-cofactor yama-enzyme amaningi, ikakhulukazi ezinqubweni zokukhiqiza amandla. Idlala indima ebalulekile ekukhiqizweni kwe-adenosine triphosphate (ATP). I-ATP iyisithwali samandla esiyinhloko samaseli, futhi ama-ion e-magnesium abalulekile ekuzinzeni nasekusebenzeni kwe-ATP.
Njengoba i-magnesium ibalulekile ekukhiqizweni kwe-ATP, ukuntuleka kwe-magnesium kungaholela ekukhiqizweni kwe-ATP okunganele, okuholela ekunciphiseni kokunikezwa kwamandla emangqamuzaneni, okubonakala njengokukhathala okuvamile.
I-Magnesium ibamba iqhaza ezinqubweni ze-metabolic ezifana ne-glycolysis, umjikelezo we-tricarboxylic acid (umjikelezo we-TCA), kanye ne-oxidative phosphorylation. Lezi zinqubo ziyizindlela eziyinhloko zamaseli zokukhiqiza i-ATP. I-molecule ye-ATP kumele ihlanganiswe nama-ion e-magnesium ukuze igcine isimo sayo esisebenzayo (i-Mg-ATP). Ngaphandle kwe-magnesium, i-ATP ayikwazi ukusebenza kahle.
I-magnesium isebenza njenge-cofactor yama-enzyme amaningi, ikakhulukazi lawo ahilelekile ekugayweni kwamandla, njenge-hexokinase, i-pyruvate kinase, kanye ne-adenosine triphosphate synthetase. Ukuntuleka kwe-magnesium kubangela ukwehla komsebenzi wala ma-enzyme, okuthinta ukukhiqizwa kwamandla kanye nokusetshenziswa kweseli.
I-magnesium inemiphumela yokulwa ne-antioxidant futhi inganciphisa ukucindezeleka kwe-oxidative emzimbeni. Ukuntuleka kwe-magnesium kwandisa amazinga okucindezeleka kwe-oxidative, okuholela ekulimaleni kwamangqamuzana kanye nokukhathala.
I-magnesium ibalulekile nasekuhambiseni imizwa kanye nokufinyela kwemisipha. Ukuntuleka kwe-magnesium kungaholela ekungasebenzi kahle kwemizwa kanye nemisipha, okwenza ukukhathala kube kubi kakhulu.

13. Isifo sikashukela, ukumelana ne-insulin kanye nezinye izifo ze-metabolic.
I-magnesium iyisici esibalulekile sokusabalalisa ama-insulin receptor futhi ihilelekile ekukhiqizweni nasekusebenzeni kwe-insulin. Ukuntuleka kwe-magnesium kungaholela ekunciphiseni ukuzwela kwama-insulin receptor futhi kwandise ingozi yokumelana ne-insulin. Ukuntuleka kwe-magnesium kuhlotshaniswa nokwanda kwezehlakalo zokumelana ne-insulin kanye nesifo sikashukela sohlobo 2.
I-magnesium ihilelekile ekusebenzeni kwama-enzyme ahlukahlukene adlala indima ebalulekile ekusetshenzisweni kwe-glucose. Ukuntuleka kwe-magnesium kuthinta i-glycolysis kanye nokusetshenziswa kwe-glucose okubangelwa yi-insulin. Izifundo zithole ukuthi ukuntuleka kwe-magnesium kungabangela ukuphazamiseka kwe-glucose metabolism, ukwandisa amazinga kashukela egazini kanye ne-glycated hemoglobin (HbA1c).
I-magnesium inemiphumela yokulwa nokuvuvukala kanye ne-antioxidant futhi inganciphisa ukucindezeleka kwe-oxidative kanye nezimpendulo zokuvuvukala emzimbeni, okuyizindlela ezibalulekile zesifo sikashukela kanye nokumelana ne-insulin. Isimo esiphansi se-magnesium sandisa izimpawu zokucindezeleka kwe-oxidative kanye nokuvuvukala, ngaleyo ndlela kukhuthaze ukuthuthukiswa kokumelana ne-insulin kanye nesifo sikashukela.
Ukwengezwa kwe-magnesium kwandisa ukuzwela kwe-insulin receptor futhi kuthuthukisa ukumuncwa kwe-glucose okubangelwa yi-insulin. Ukwengezwa kwe-magnesium kungathuthukisa i-metabolism ye-glucose futhi kunciphise i-glucose yegazi esheshayo kanye namazinga e-hemoglobin e-glycated ngezindlela eziningi. I-magnesium inganciphisa ingozi ye-metabolic syndrome ngokuthuthukisa ukuzwela kwe-insulin, ukwehlisa umfutho wegazi, ukunciphisa ukungasebenzi kahle kwamafutha, kanye nokunciphisa ukuvuvukala.

14. Ubuhlungu bekhanda kanye ne-migraines.
I-magnesium idlala indima ebalulekile ekukhululweni nasekulawulweni kwe-neurotransmitter yokusebenza kwemithambo yegazi. Ukuntuleka kwe-magnesium kungaholela ekungalinganini kwe-neurotransmitter kanye ne-vasospasm, okungabangela ikhanda elibuhlungu kanye ne-migraines.
Amazinga aphansi e-magnesium ahlotshaniswa nokuvuvukala okukhulu kanye nokucindezeleka kwe-oxidative, okungase kubangele noma kube kubi kakhulu i-migraines. I-magnesium inemiphumela yokulwa nokuvuvukala kanye ne-antioxidant, inciphisa ukuvuvukala kanye nokucindezeleka kwe-oxidative.
I-magnesium isiza ukuphumula imithambo yegazi, ukunciphisa i-vasospasm, nokuthuthukisa ukugeleza kwegazi, ngaleyo ndlela kunciphise i-migraines.

15. Izinkinga zokulala ezifana nokungalali kahle, izinga eliphansi lokulala, ukuphazamiseka kwesigqi se-circadian, kanye nokuvuka kalula.
Imiphumela yokulawula ye-magnesium ohlelweni lwezinzwa isiza ekukhuthazeni ukuphumula nokuzola, kanti ukwengezwa kwe-magnesium kungathuthukisa kakhulu ubunzima bokulala ezigulini ezinenkinga yokungalali futhi kusize ekwandiseni isikhathi sokulala sonke.
I-Magnesium ikhuthaza ubuthongo obujulile futhi ithuthukisa ikhwalithi yokulala iyonke ngokulawula umsebenzi wama-neurotransmitter njenge-GABA.
I-magnesium idlala indima ebalulekile ekulawuleni iwashi lebhayoloji lomzimba. I-magnesium ingasiza ekubuyiseleni isigqi se-circadian esijwayelekile ngokuthinta ukukhiqizwa kwe-melatonin.
Umphumela wokudambisa we-magnesium unganciphisa inani lokuvuka ebusuku futhi ukhuthaze ubuthongo obuqhubekayo.

16. Ukuvuvukala.
I-calcium eningi ingaholela kalula ekuvuvukeni, kanti i-magnesium ingavimbela ukuvuvukala.
I-magnesium iyisici esibalulekile ekusebenzeni okuvamile kwesimiso somzimba sokuzivikela. Ukuntuleka kwe-magnesium kungaholela ekusebenzeni okungavamile kwamaseli omzimba futhi kwandise ukusabela kokuvuvukala.
Ukuntuleka kwe-magnesium kuholela emazingeni aphezulu okucindezeleka kwe-oxidative futhi kwandisa ukukhiqizwa kwama-free radicals emzimbeni, okungabangela futhi kukhulise ukuvuvukala. Njenge-antioxidant yemvelo, i-magnesium ingaqeda ama-free radicals emzimbeni futhi inciphise ukucindezeleka kwe-oxidative kanye nokusabela kokuvuvukala. Ukwengezwa kwe-magnesium kunganciphisa kakhulu amazinga ezimpawu zokucindezeleka kwe-oxidative futhi kunciphise ukuvuvukala okuhlobene nokucindezeleka kwe-oxidative.
I-Magnesium inemiphumela yokulwa nokuvuvukala ngezindlela eziningi, okuhlanganisa ukuvimbela ukukhishwa kwama-cytokines abangela ukuvuvukala kanye nokunciphisa ukukhiqizwa kwabaxhumanisi bokuvuvukala. I-Magnesium ingavimbela amazinga ezici ezibangela ukuvuvukala njenge-tumor necrosis factor-α (TNF-α), i-interleukin-6 (IL-6), kanye ne-C-reactive protein (CRP).

17. Isifo Sokukhuhlana Kwamathambo.
Ukuntuleka kwe-magnesium kungaholela ekunciphiseni ukuqina kwamathambo kanye namandla amathambo. I-magnesium iyisici esibalulekile enqubweni yokwakheka kwamathambo futhi ihileleke ngqo ekwakhekeni kwe-bone matrix. I-magnesium enganele ingaholela ekwehleni kwekhwalithi ye-bone matrix, okwenza amathambo abe sengozini yokulimala.
Ukuntuleka kwe-magnesium kungaholela ekuweni kwe-calcium emathanjeni, kanti i-magnesium idlala indima ebalulekile ekulawuleni ibhalansi ye-calcium emzimbeni. I-magnesium ikhuthaza ukumuncwa nokusetshenziswa kwe-calcium ngokusebenzisa i-vitamin D, futhi ilawula nokusetshenziswa kwe-calcium ngokuthinta ukukhiqizwa kwe-parathyroid hormone (PTH). Ukuntuleka kwe-magnesium kungaholela ekusebenzeni okungajwayelekile kwe-PTH kanye ne-vitamin D, ngaleyo ndlela kubangele ukuphazamiseka kwe-calcium metabolism futhi kwandise ingozi yokuphuma kwe-calcium emathanjeni.
I-magnesium isiza ekuvimbeleni ukubekwa kwe-calcium ezicutshini ezithambile futhi igcina isitoreji esifanele se-calcium emathanjeni. Uma i-magnesium intuleka, i-calcium ilahleka kalula emathanjeni futhi ibekwe ezicutshini ezithambile.

20. Ukuqaqamba kwemisipha nokuqaqamba, ubuthakathaka bemisipha, ukukhathala, ukuthuthumela kwemisipha okungavamile (ukudikiza kwamehlo, ukuluma ulimi, njll.), ubuhlungu bemisipha obungapheli kanye nezinye izinkinga zemisipha.
I-magnesium idlala indima ebalulekile ekuqhutshweni kwezinzwa kanye nokugoba kwemisipha. Ukuntuleka kwe-magnesium kungabangela ukuqhutshwa kwemizwa okungavamile kanye nokwanda kokujabula kwamaseli emisipha, okuholela ekugugulekeni kwemisipha kanye nokugoba. Ukwengeza i-magnesium kungabuyisela ukusebenza okujwayelekile kokuqhutshwa kwemizwa kanye nokugoba kwemisipha futhi kunciphise ukujabula okukhulu kwamaseli emisipha, ngaleyo ndlela kuncishiswe ukugoba kanye nokugoba.
I-magnesium ihilelekile ekugayweni kwamandla kanye nokukhiqizwa kwe-ATP (umthombo wamandla oyinhloko weseli). Ukuntuleka kwe-magnesium kungaholela ekunciphiseni ukukhiqizwa kwe-ATP, okuthinta ukufinyela kwemisipha kanye nokusebenza kwayo, okuholela ebuthakathakeni bemisipha kanye nokukhathala. Ukuntuleka kwe-magnesium kungaholela ekukhathaleni okukhulu kanye nokwehla kwamandla okuzivocavoca ngemva kokuzivocavoca. Ngokuhlanganyela ekwakhiweni kwe-ATP, i-magnesium inikeza amandla anele, ithuthukisa ukusebenza kokufinyela kwemisipha, ithuthukisa amandla emisipha, futhi inciphise ukukhathala. Ukwengeza i-magnesium kungathuthukisa ukukhuthazela kokuzivocavoca kanye nokusebenza kwemisipha futhi kunciphise ukukhathala ngemva kokuzivocavoca.
Umphumela wokulawula we-magnesium ohlelweni lwezinzwa ungathinta ukufinyela kwemisipha ngokuzithandela. Ukuntuleka kwe-magnesium kungabangela ukungasebenzi kahle kwesistimu yezinzwa, okubangela ukuthuthumela kwemisipha kanye ne-restless legs syndrome (RLS). Imiphumela yokudambisa ye-magnesium inganciphisa ukujabula ngokweqile kwesistimu yezinzwa, inciphise izimpawu ze-RLS, futhi ithuthukise ikhwalithi yokulala.
I-Magnesium inezakhiwo zokulwa nokuvuvukala kanye ne-antioxidant, inciphisa ukuvuvukala kanye nokucindezeleka kwe-oxidative emzimbeni. Lezi zici zihlotshaniswa nobuhlungu obungapheli. I-Magnesium ibandakanyeka ekulawulweni kwama-neurotransmitter amaningi, njenge-glutamate kanye ne-GABA, adlala indima ebalulekile ekuboneni ubuhlungu. Ukuntuleka kwe-magnesium kungaholela ekulawulweni okungavamile kobuhlungu kanye nokwanda kokubona ubuhlungu. Ukwengezwa kwe-magnesium kunganciphisa izimpawu zobuhlungu obungapheli ngokulawula amazinga e-neurotransmitter.

21. Ukulimala kwezemidlalo kanye nokululama.
I-magnesium idlala indima ebalulekile ekuqhubeni izinzwa kanye nokufinyela kwemisipha. Ukuntuleka kwe-magnesium kungabangela ukucasuka kwemisipha kanye nokufinyela okungahleliwe, okwandisa ingozi yokufinyela nokuqaqamba. Ukwengeza i-magnesium kungalawula ukusebenza kwezinzwa kanye nemisipha futhi kunciphise ukufinyela kwemisipha kanye nokuqaqamba ngemva kokuzivocavoca.
I-magnesium iyisici esibalulekile se-ATP (umthombo wamandla oyinhloko weseli) futhi ihilelekile ekukhiqizweni kwamandla kanye nokusetshenziswa kwamandla emzimbeni. Ukuntuleka kwe-magnesium kungaholela ekukhiqizweni kwamandla okunganele, ukukhathala okwandisiwe, kanye nokusebenza kahle kwezemidlalo okuncishisiwe. Ukwengezwa kwe-magnesium kungathuthukisa ukukhuthazela kokuzivocavoca futhi kunciphise ukukhathala ngemva kokuzivocavoca.
I-Magnesium inezakhiwo zokulwa nokuvuvukala ezinganciphisa impendulo yokuvuvukala ebangelwa ukuzivocavoca futhi isheshise ukululama kwemisipha nezicubu.
I-lactic acid iyi-metabolite ekhiqizwa ngesikhathi se-glycolysis futhi ikhiqizwa ngobuningi obukhulu ngesikhathi sokuzivocavoca okunzima. I-magnesium iyi-cofactor yama-enzyme amaningi ahlobene ne-metabolism yamandla (njenge-hexokinase, i-pyruvate kinase), edlala indima ebalulekile ku-glycolysis kanye ne-lactate metabolism. I-magnesium isiza ukusheshisa ukususwa nokuguqulwa kwe-lactic acid futhi inciphise ukuqongelela kwe-lactic acid.

 

Ungahlola kanjani ukuthi awunayo i-magnesium eyanele?

Uma ngikhuluma iqiniso, ukuzama ukuthola izinga langempela le-magnesium emzimbeni wakho ngokusebenzisa izinto zokuhlola ezijwayelekile empeleni kuyinkinga eyinkimbinkimbi kakhulu.

Kukhona cishe amagremu angu-24-29 e-magnesium emzimbeni wethu, cishe ingxenye eyodwa kwezintathu yawo isemathanjeni kanye nengxenye eyodwa kwezintathu emaseli nasezicutshini ezahlukahlukene. I-magnesium egazini ihlanganisa cishe u-1% wokuqukethwe kwe-magnesium emzimbeni wonke (kufaka phakathi i-serum engu-0.3% kuma-erythrocyte kanye no-0.5% emaseli abomvu egazi).
Njengamanje, ezibhedlela eziningi eShayina, ukuhlolwa okuvamile kokuqukethwe kwe-magnesium ngokuvamile kuba "ukuhlolwa kwe-serum magnesium". Ububanzi obujwayelekile balolu vivinyo buphakathi kuka-0.75 no-0.95 mmol/L.

Kodwa-ke, ngenxa yokuthi i-magnesium esegazini ingaphansi kwe-1% kuphela yokuqukethwe kwe-magnesium emzimbeni wonke, ayikwazi ukukhombisa ngempela nangokunembile okuqukethwe kwe-magnesium ezicutshini nasemaseli ahlukahlukene omzimba.

Okuqukethwe kwe-magnesium ku-serum kubaluleke kakhulu emzimbeni futhi kuyinto eza kuqala. Ngoba i-magnesium ku-serum kumele igcinwe isezingeni elifanele ukuze kugcinwe imisebenzi ethile ebalulekile, njengokushaya kwenhliziyo okuphumelelayo.

Ngakho-ke uma ukudla kwakho i-magnesium kuqhubeka nokuntula, noma umzimba wakho ubhekene nesifo noma ukucindezeleka, umzimba wakho uzoqala ngokukhipha i-magnesium ezicutshini noma emaseli njengemisipha bese uyithutha uyiyise egazini ukuze usize ukugcina amazinga ajwayelekile e-magnesium egazini.

Ngakho-ke, uma inani lakho le-magnesium egazini libonakala lingaphakathi kwesilinganiso esijwayelekile, i-magnesium ingase inciphe kwezinye izicubu namaseli omzimba.

Futhi uma uhlola futhi uthola ukuthi ngisho ne-serum magnesium iphansi, isibonelo, ingaphansi kwesilinganiso esijwayelekile, noma iseduze nomkhawulo ophansi wesilinganiso esijwayelekile, kusho ukuthi umzimba usuvele usesimweni sokuntuleka okukhulu kwe-magnesium.

Izinga le-magnesium lamaseli abomvu egazi (RBC) kanye nokuhlolwa kwezinga le-magnesium lama-platelet kunembile kakhulu kunokuhlolwa kwe-magnesium egazini. Kodwa akukameli ngempela amazinga e-magnesium angempela emzimbeni.

Ngenxa yokuthi amangqamuzana abomvu egazi noma ama-platelet awanayo i-nuclei ne-mitochondria, i-mitochondria iyisici esibaluleke kakhulu sokugcina i-magnesium. Ama-platelet abonisa ngokunembile izinguquko zakamuva emazingeni e-magnesium kunamaseli abomvu egazi ngoba ama-platelet aphila izinsuku ezingu-8-9 kuphela uma kuqhathaniswa nezinsuku ezingu-100-120 zamaseli abomvu egazi.

Ukuhlolwa okunembe kakhulu yilezi: i-biopsy yamaseli emisipha okuqukethwe kwe-magnesium, okuqukethwe kwe-magnesium yamaseli e-epithelial angaphansi kolimi.
Kodwa-ke, ngaphezu kwe-serum magnesium, izibhedlela zasekhaya okwamanje azikwazi ukwenza okuningi kwezinye izivivinyo ze-magnesium.
Yingakho uhlelo lwezokwelapha lwendabuko selunesikhathi eside lungakunaki ukubaluleka kwe-magnesium, ngoba ukwahlulela nje ukuthi isiguli asinayo i-magnesium ngokulinganisa amanani e-magnesium egazini kuvame ukuholela ekuhluleleni kabi.
Ukwahlulela izinga le-magnesium yesiguli ngokulinganisa i-magnesium esegazini kuphela kuyinkinga enkulu ekuxilongweni nasekwelashweni kwamanje.

Ungakhetha kanjani isithasiselo se-magnesium esifanele?

Kunezinhlobo ezingaphezu kweshumi nambili ezahlukene zezithako ze-magnesium emakethe, njenge-magnesium oxide, i-magnesium sulfate, i-magnesium chloride, i-magnesium citrate, i-magnesium glycinate, i-magnesium threonate, i-magnesium taurate, njll.
Nakuba izinhlobo ezahlukene zezithako ze-magnesium zingathuthukisa inkinga yokuntuleka kwe-magnesium, ngenxa yokwehluka kwesakhiwo sama-molecule, amazinga okumuncwa ahluka kakhulu, futhi anezimpawu zawo kanye nokusebenza kahle kwawo.
Ngakho-ke, kubaluleke kakhulu ukukhetha isithasiselo se-magnesium esikufanele futhi esixazulula izinkinga ezithile.

Ungafunda ngokucophelela okuqukethwe okulandelayo, bese ukhetha uhlobo lwesithasiselo se-magnesium esikufanele kakhulu ngokusekelwe ezidingweni zakho kanye nezinkinga ofuna ukugxila kuzo ekuxazululeni.

Izithasiselo ze-magnesium azinconywa

i-magnesium oxide

Inzuzo ye-magnesium oxide ukuthi inokuqukethwe okuphezulu kwe-magnesium, okungukuthi, igremu ngalinye le-magnesium oxide linganikeza ama-ion amaningi e-magnesium kunezinye izithako ze-magnesium ngentengo ephansi.

Kodwa-ke, lesi isithasiselo se-magnesium esinezinga eliphansi kakhulu lokumuncwa, cishe u-4% kuphela, okusho ukuthi iningi le-magnesium alikwazi ukumuncwa futhi lisetshenziswe ngempela.

Ngaphezu kwalokho, i-magnesium oxide inomphumela omuhle wokukhipha isisu futhi ingasetshenziswa ukwelapha ukuqunjelwa.

Ithambisa indle ngokumunca amanzi emathunjini, ikhuthaza i-peristalsis yamathumbu, futhi isize ekukhululeni indle. Imithamo ephezulu ye-magnesium oxide ingabangela ukuphazamiseka kwesisu, okuhlanganisa uhudo, ubuhlungu besisu, kanye nokuqaqamba kwesisu. Abantu abanokuzwela kwesisu kufanele basebenzise ngokuqapha.

I-magnesium sulfate

Izinga lokumuncwa kwe-magnesium sulfate nalo liphansi kakhulu, ngakho-ke iningi le-magnesium sulfate ethathwa ngomlomo ayikwazi ukumuncwa futhi izokhishwa kanye nendle esikhundleni sokumuncwa egazini.

I-Magnesium sulfate nayo inomphumela obalulekile wokukhipha isisu, futhi umphumela wayo wokukhipha isisu uvame ukubonakala zingakapheli imizuzu engama-30 kuya emahoreni ayi-6. Lokhu kungenxa yokuthi ama-ion e-magnesium angamuncwanga amunca amanzi emathunjini, andise umthamo wokuqukethwe kwamathumbu, futhi akhuthaze ukuphuma kwendle.
Kodwa-ke, ngenxa yokuncibilika kwayo emanzini, i-magnesium sulfate ivame ukusetshenziswa ngomjovo we-intravenous ezimweni eziphuthumayo esibhedlela ukwelapha i-acute hypomagnesemia, i-eclampsia, ukuhlaselwa yi-asthma okukhulu, njll.

Ngaphandle kwalokho, i-magnesium sulfate ingasetshenziswa njengosawoti wokugeza (owaziwa nangokuthi usawoti we-Epsom), odonswa esikhumbeni ukuze kuncishiswe ubuhlungu bemisipha nokuvuvukala futhi kukhuthazwe ukuphumula nokululama.

i-magnesium aspartate

I-Magnesium aspartate iwuhlobo lwe-magnesium olwakhiwe ngokuhlanganisa i-aspartic acid ne-magnesium, okuyisengezo se-magnesium esiphikisanayo.
Inzuzo yile: I-Magnesium aspartate inokutholakala okuphezulu kwe-bioavailability, okusho ukuthi ingamuncwa ngempumelelo futhi isetshenziswe ngumzimba ukwandisa ngokushesha amazinga e-magnesium egazini.
Ngaphezu kwalokho, i-aspartic acid iyi-amino acid ebalulekile ehilelekile ekugayweni kwamandla. Idlala indima ebalulekile emjikelezweni we-tricarboxylic acid (umjikelezo we-Krebs) futhi isiza amaseli ukukhiqiza amandla (i-ATP). Ngakho-ke, i-magnesium aspartate ingasiza ekwandiseni amazinga amandla futhi inciphise imizwa yokukhathala.
Kodwa-ke, i-aspartic acid iyi-amino acid evuselelayo, futhi ukudla ngokweqile kungabangela ukucasuka ngokweqile kwesimiso sezinzwa, okuholela ekukhathazekeni, ukungakwazi ukulala, noma ezinye izimpawu zezinzwa.
Ngenxa yokuvukwa yi-aspartate, abantu abathile abazwela ama-amino acid avusa imizwa (njengeziguli ezinezifo ezithile zemizwa) bangase bangafaneleki ukuphathwa isikhathi eside noma ngomthamo ophezulu we-magnesium aspartate.

Izithasiselo zeMagnesium ezinconyiwe

I-Magnesium L-Threonate

I-Magnesium threonate yakhiwa ngokuhlanganisa i-magnesium ne-L-threonate. I-Magnesium threonate inezinzuzo ezibalulekile ekuthuthukiseni ukusebenza kwengqondo, ekunciphiseni ukukhathazeka nokudangala, ekusizeni ukulala, kanye nokuvikela izinzwa ngenxa yezakhiwo zayo zamakhemikhali ezihlukile kanye nokungena kahle kwesithiyo segazi ebuchosheni.

Ingena Esivimbelweni Segazi Nobuchopho: I-Magnesium threonate iboniswe isebenza kangcono ekungeneni esivimbelweni segazi nobuchopho, iyinika inzuzo eyingqayizivele ekwandiseni amazinga e-magnesium yobuchopho. Izifundo zikhombisile ukuthi i-magnesium threonate ingakhuphula kakhulu amazinga e-magnesium ku-cerebrospinal fluid, ngaleyo ndlela ithuthukise ukusebenza kwengqondo.

Ithuthukisa ukusebenza kwengqondo kanye nenkumbulo: Ngenxa yekhono layo lokukhulisa amazinga e-magnesium ebuchosheni, i-magnesium threonate ingathuthukisa kakhulu ukusebenza kwengqondo kanye nenkumbulo, ikakhulukazi kubantu asebekhulile kanye nalabo abanokukhubazeka kwengqondo. Ucwaningo lubonisa ukuthi ukwengezwa kwe-magnesium threonate kungathuthukisa kakhulu ikhono lokufunda lobuchopho kanye nokusebenza kwenkumbulo yesikhashana.

Ukuqeda Ukukhathazeka Nokucindezeleka: I-Magnesium idlala indima ebalulekile ekuqhutshweni kwezinzwa kanye nokulinganisela kwe-neurotransmitter. I-Magnesium threonate ingasiza ekunciphiseni izimpawu zokukhathazeka nokucindezeleka ngokwandisa amazinga e-magnesium ebuchosheni ngempumelelo.
Ukuvikelwa Kwezinzwa: Abantu abasengozini yezifo eziwohlokayo zemizwa, njengesifo i-Alzheimer's kanye ne-Parkinson's. I-Magnesium threonate inemiphumela yokuvikela izinzwa futhi iyasiza ekuvimbeleni nasekunciphiseni ukuqhubeka kwezifo eziwohlokayo zemizwa.

I-Magnesium Taurate

I-Magnesium taurine iyinhlanganisela ye-magnesium ne-taurine. Ihlanganisa izinzuzo ze-magnesium ne-taurine futhi iyisengezo esihle kakhulu se-magnesium.
Ukutholakala okuphezulu kwe-bioavailability: I-Magnesium taurate inokutholakala okuphezulu kwe-bioavailability, okusho ukuthi umzimba ungamunca kalula futhi usebenzise lolu hlobo lwe-magnesium.
Ukubekezelelana okuhle kwesisu: Ngenxa yokuthi i-magnesium taurate inesilinganiso esiphakeme sokumuncwa emgodini wesisu, ngokuvamile ayibangeli ukungakhululeki kwesisu.

Isekela impilo yenhliziyo: I-Magnesium ne-taurine zombili ziyasiza ekulawuleni ukusebenza kwenhliziyo. I-Magnesium isiza ekugcineni isigqi senhliziyo esijwayelekile ngokulawula ukugcwala kwe-calcium ion emaseli emisipha yenhliziyo. I-Taurine inezakhiwo zokulwa ne-antioxidant kanye nokulwa nokuvuvukala, ivikela amaseli enhliziyo ekucindezelekeni kwe-oxidative kanye nomonakalo wokuvuvukala. Izifundo eziningi zikhombisile ukuthi i-magnesium taurine inezinzuzo ezibalulekile zempilo yenhliziyo, yehlisa umfutho wegazi ophakeme, yehlisa ukushaya kwenhliziyo okungajwayelekile, futhi ivikela ekuhlaselweni yinhliziyo.

Impilo Yesimiso Sezinzwa: I-Magnesium ne-taurine zombili zidlala indima ebalulekile ohlelweni lwezinzwa. I-Magnesium iyi-coenzyme ekwakhiweni kwama-neurotransmitter ahlukahlukene futhi isiza ukugcina ukusebenza okujwayelekile kohlelo lwezinzwa. I-Taurine ivikela amangqamuzana ezinzwa futhi ikhuthaza impilo ye-neuronal. I-Magnesium taurine ingaqeda izimpawu zokukhathazeka nokudangala futhi ithuthukise ukusebenza kohlelo lwezinzwa. Kubantu abanokukhathazeka, ukucindezeleka, ukucindezeleka okungapheli kanye nezinye izimo zezinzwa.

Imiphumela yokulwa nokuvuvukala kanye ne-antioxidant: I-Taurine inemiphumela enamandla yokulwa nokuvuvukala kanye ne-antioxidant, enganciphisa ukucindezeleka kwe-oxidative kanye nezimpendulo zokuvuvukala emzimbeni. I-Magnesium futhi iyasiza ekulawuleni amasosha omzimba futhi yehlise ukuvuvukala. Ucwaningo lubonisa ukuthi i-magnesium taurate ingasiza ekuvimbeleni izifo ezahlukahlukene ezingamahlalakhona ngezakhiwo zayo zokulwa nokuvuvukala kanye ne-antioxidant.

Kuthuthukisa impilo ye-metabolic: I-Magnesium idlala indima ebalulekile ekusetshenzisweni kwamandla, ekukhiqizweni nasekusetshenzisweni kwe-insulin, kanye nokulawulwa koshukela egazini. I-Taurine futhi iyasiza ekuthuthukiseni ukuzwela kwe-insulin, isize ekulawuleni ushukela egazini, futhi ithuthukise i-metabolic syndrome kanye nezinye izinkinga. Lokhu kwenza i-magnesium taurine isebenze kangcono kunezinye izithasiselo ze-magnesium ekuphathweni kwe-metabolic syndrome kanye nokumelana ne-insulin.

I-Taurine ku-Magnesium Taurate, njenge-amino acid eyingqayizivele, nayo inemiphumela eminingi:

I-Taurine iyi-amino acid yemvelo equkethe i-sulfur futhi iyi-amino acid engeyona iphrotheni ngoba ayihilelekile ekwakhiweni kwamaprotheni njengamanye ama-amino acid.

Lesi sakhi sisabalala kabanzi ezicutshini zezilwane ezahlukahlukene, ikakhulukazi enhliziyweni, ebuchosheni, emehlweni, nasemisipheni yamathambo. Sitholakala futhi ekudleni okuhlukahlukene, njengenyama, inhlanzi, imikhiqizo yobisi, kanye neziphuzo ezinikeza amandla.

I-Taurine emzimbeni womuntu ingakhiqizwa yi-cysteine ​​​​ngaphansi kwesenzo se-cysteine ​​​​sulfinic acid decarboxylase (Csad), noma ingatholakala ekudleni futhi imuncwe amaseli ngokusebenzisa abathuthi be-taurine.

Njengoba iminyaka ikhula, ukugcwala kwe-taurine kanye nama-metabolites ayo emzimbeni womuntu kuzoncipha kancane kancane. Uma kuqhathaniswa nabantu abasha, ukugcwala kwe-taurine egazini labantu asebekhulile kuzoncipha ngaphezu kuka-80%.

1. Sekela impilo yenhliziyo nemithambo yegazi:

Ilawula umfutho wegazi: I-Taurine isiza ukwehlisa umfutho wegazi futhi ikhuthaza ukugeleza kwegazi ngokulawula ibhalansi yama-ion e-sodium, i-potassium ne-calcium. I-Taurine inganciphisa kakhulu amazinga omfutho wegazi ezigulini ezine-hypertension.

Ivikela inhliziyo: Inemiphumela yokulwa nama-antioxidant futhi ivikela ama-cardiomyocyte ekulimaleni okubangelwa ukucindezeleka kwe-oxidative. Ukwengezwa kwe-taurine kungathuthukisa ukusebenza kwenhliziyo futhi kunciphise ingozi yesifo senhliziyo.

2. Vikela impilo yesimiso sezinzwa:

Ukuvikela Imizwa: I-Taurine inemiphumela yokuvikela imizwa, ivimbela izifo eziwohlokayo zemizwa ngokuqinisa ulwelwesi lwamaseli nokulawula ukugcwala kwe-calcium ion, ivimbela ukucasuka ngokweqile kanye nokufa kwemizwa.

Umphumela wokuzola: Unemiphumela yokudambisa nokukhathazeka, okusiza ukuthuthukisa isimo sengqondo nokunciphisa ukucindezeleka.

3. Ukuvikelwa kokubona:

Ukuvikelwa kwe-retinal: I-Taurine iyisici esibalulekile se-retinal, esiza ekugcineni ukusebenza kwe-retinal nokuvimbela ukuwohloka kombono.

Umphumela we-Antioxidant: Unganciphisa umonakalo wama-free radical kumaseli e-retinal futhi ubambezele ukwehla kokubona.

4. Impilo ye-Metabolic:

Ukulawula ushukela egazini: i-taurine ingasiza ekuthuthukiseni ukuzwela kwe-insulin, ilawule amazinga kashukela egazini, futhi ivimbele isifo se-metabolic.

Ukuguqulwa kwe-Liposy: Kusiza ekulawuleni ukuguqulwa kwe-lipid futhi kwehlise izinga le-cholesterol kanye ne-triglyceride egazini.

5. Ukusebenza kokuzivocavoca:

Ukunciphisa ukukhathala kwemisipha: I-Telonic acid inganciphisa ukucindezeleka kwe-oxidative kanye nokuvuvukala ngesikhathi sokuzivocavoca, inciphise ukukhathala kwemisipha.

Thuthukisa ukukhuthazela: Kungathuthukisa ukufinyela kwemisipha kanye nokukhuthazela, futhi kuthuthukise ukusebenza kokuzivocavoca.