I-Spermidine, i-activator enamandla yenqubo yokuvuselela amaseli, ibhekwa kabanzi "njengomthombo wobusha." Le micronutrient ngamakhemikhali i-polyamine futhi ikhiqizwa ikakhulukazi amagciwane amathumbu emizimbeni yethu. Ngaphezu kwalokho, i-spermidine nayo ingamuncwa ngumzimba ngokudla. Ucwaningo lubonisa ukuthi i-spermidine, kungakhathaliseki ukuthi ihlinzekwa ngaphandle noma ikhiqizwa i-microbiome yomzimba, isebenza ngendlela ehambisanayo.
Ukugxila kwe-spermidine engapheli kungase kwehle ngokukhula, futhi kungase kube khona ukuxhumana phakathi kwalokhu kanye nokuwohloka okuhlobene neminyaka ekusebenzeni komzimba. I-Spermidine itholakala ekudleni okuningi, kanti i-grapefruit ingenye yokudla okucebile kakhulu nge-spermidine. Ezinye izifundo zithole ukuthi i-spermidine ayigcini nje ngokubambezela inqubo yokuguga kodwa ingase futhi ikhuthaze impilo nokuphila isikhathi eside. Lokhu okutholakele kwenza i-spermidine ibe ngesinye sezihloko ezishisayo zocwaningo lwamanje.
Ezintweni eziphilayo, ukugxila kwezicubu zei-spermidineukwehla ngendlela encike eminyakeni yobudala; kodwa-ke, abanempilo enempilo engu-90- kanye nekhulunyaka banamazinga e-spermidine asondelene nawabantu abasha (abaneminyaka ephakathi). Ucwaningo lwe-epidemiological lubike ubudlelwano obuhle phakathi kokudla ama-spermidine kanye nempilo yabantu. Abahlanganyeli abangu-829 abaneminyaka engu-45-84 balandelwa iminyaka engu-15. Ukungena kwe-Spermidine kulinganiselwa njalo eminyakeni engu-5 ngokusekelwe kuhlu lwemibuzo lokudla. Ucwaningo luthole ukuthi abantu abadla kakhulu i-spermidine baye banciphisa amazinga omdlavuza kanye nesifo senhliziyo futhi bahlotshaniswa nokusinda okuphelele.
◆Indlela yokulwa nokuguga
Ngo-2023, i-"Cell" yashicilela i-athikili ukuthi kunezimpawu zokuguga eziyi-12, okuhlanganisa ukungazinzi kwe-genome, i-telomere attrition, izinguquko ze-epigenetic, ukulahleka kwe-protein homeostasis, ukungakwazi kwe-macroautophagy, ukuphazamiseka kokuzwa izakhi, ukungasebenzi kahle kwe-mitochondrial, kanye nokuvela kwamaselula. Ukukhathala kwe-stem cell, ukuxhumana okushintshiwe kwe-intercellular, ukuvuvukala okungapheli, kanye ne-dysbiosis.
● Ukwethulwa kwe-autophagy
Njengamanje, ukufakwa kwe-autophagy kubhekwa njengendlela eyinhloko lapho i-spermidine ibambezela ukuguga. Ucwaningo luye lwathola ukuthi i-spermidine yenza i-dephosphorylation ye-protein kinase B, iqala ukuthuthwa kwe-forkhead box transcription factor O (FoxO) ku-nucleus, okuholela ekwandeni kokubhala kwe-FoxO target gene autophagy microtubule-associated protein light chain 3 (LC3) ). Thuthukisa i-autophagy.
Ngaphezu kwalokho, i-spermidine itholakale isiza ukubambezela ukuguga kwamangqamuzana egciwane labesifazane okubangelwa ukucindezeleka okwenziwe nge-oxidative futhi kugcinwe ukuzala kwabesifazane. Ucwaningo lomtholampilo olwathatha unyaka wonke lwathola ukuthi amazinga esidoda athuthukiswa kumavolontiya wesilisa anempilo lapho enikezwa i-spermidine; ocwaningweni lwango-2022, ucwaningo lwabheka iziguli ezingama-377 ze-acute myocardial infarction (AMI). bathola ukuthi abantu abanamazinga aphezulu e-spermidine egazini labo babenamathuba angcono okusinda kuneziguli zesifo senhliziyo ezinamazinga aphansi e-spermidine; iphephabhuku lango-2021 lithole ukuthi ukudla okuphezulu kwe-spermidine Kunokuxhumana phakathi komthamo kanye nengozi encishisiwe yokukhubazeka kwengqondo kubantu, okuzuzisa kakhulu ubuchopho ekuthuthukiseni ukuqonda kanye nokuvimbela izifo ezivamile zobuchopho ezihlobene neminyaka.
●Libazisa ukuguga kwe-telomere
Ukuguga kubangela ukuwohloka okuningi kwamangqamuzana, amaselula, kanye nokuwohloka komzimba, okuhlanganisa ukuhluleka kwenhliziyo, i-neurodegeneration, i-metabolic maladaptation, i-telomere attrition, nokulahlekelwa izinwele. Kuyathakazelisa ukuthi ezingeni lamangqamuzana, ikhono lokufaka i-autophagy (umshini oyinhloko wesenzo se-spermidine) liyancipha ngokukhula, into ekhona kumamodeli amaningi ezinto eziphilayo futhi kucatshangwa ukuthi ihlobene eduze nokuguga. .
● I-Antioxidant kanye nemiphumela eqeda ukuvuvukala
Ukucindezeleka kwe-oxidative kuyisici esibalulekile esiholela ekugugeni kwamangqamuzana nokulimala. I-Spermidine inezakhiwo ze-antioxidant. Abacwaningi bondle amagundane i-spermidine engavamile izinyanga ezintathu futhi babona izinguquko kuma-ovari. Ngemuva kokwelashwa kwe-spermidine, iqembu, inani le-atrophic follicles (i-follicles ewohlokile) lancishiswa kakhulu, umsebenzi we-antioxidant enzyme wanda, futhi amazinga e-malondialdehyde (MDA) ayancipha, anganciphisa amazinga e-oxygen esebenzayo (ROS), okubonisa ukunciphisa ukucindezeleka kwe-oxidative ku-spermidine. iqembu elilashiwe .
Ukuvuvukala okungapheli kubonakala kungenakugwema njengoba sikhula. Ukwenyuka kwe-spermidine kusiza ukugqugquzela ukukhiqizwa kwama-cytokines aphikisana nokuvuvukala ngenkathi kunciphisa ukukhiqizwa kwama-cytokines ane-pro-inflammatory. Ucwaningo lwakamuva lubonisa ukuthi i-spermidine iphinde ithuthukise izakhiwo zokulwa nokuvuvukala kwama-macrophages.
●Vimba ukuguga kwe-stem cell
I-Spermidine ikhuthaza umsebenzi we-mitochondrial kanye nokukhiqizwa kwe-keratin kumaseli we-epithelial stem, ngokuqhubekayo ukuqinisekisa ukuvuselelwa kwemisipha nezinwele.
I-Spermidineiyinhlanganisela ye-polyamine ngokwemvelo etholakala ezintweni eziphilayo. Njengoba iyinhlanganisela ye-polyamine, inamaqembu amaningi e-amino (-NH2). Lawa maqembu aphinde ayinikeze okuyingqayizivele futhi ebaluleke kakhulu Ukunambitheka kwegama.
Kungenxa yalawa maqembu e-amino ukuthi angakwazi ukusebenzisana nezinhlobonhlobo zama-biomolecules futhi enze imisebenzi yawo yomzimba ngaphakathi kwamaseli. Isibonelo, idlala indima ebalulekile ekukhuleni kwamangqamuzana, ekuhlukaniseni, ekulawuleni izakhi zofuzo, nasekulweni nokuguga.
Anti ukuguga
Izinga le-Spermidine liwuphawu olubonisa izinga lokuguga komzimba. Njengoba umzimba uguga, okuqukethwe kwe-spermidine emzimbeni nakho kuyehla. Ucwaningo luye lwabonisa ukuthi i-spermidine ingabambezela ukuguga kwamangqamuzana afana namaseli emvubelo namangqamuzana ancelisayo, futhi yandise isikhathi sokuphila sezinhlobo zezilwane ezingenamgogodla ezifana ne-Drosophila melanogaster kanye ne-Caenorhabditis elegans namagundane.
Njengamanje, ukufakwa kwe-autophagy kuye kwafakazelwa ukuthi kungenye yezindlela eziyinhloko lapho i-spermidine ibambezela ukuguga futhi yandise isikhathi sokuphila. Ucwaningo luye lwabonisa ukuthi ngemva kokukhipha izakhi zofuzo ezibalulekile ku-autophagy imvubelo yokuguga, i-Drosophila namangqamuzana ancelisayo akhulisiwe, lezi zilwane eziyisibonelo azizange zibe nempilo enwetshiwe ngemva kokwelashwa nge-spermidine. Ngaphezu kwalokho, i-spermidine iphinde isebenze ngezindlela ezinjengokunciphisa i-histone acetylation.
I-Antioxidant
I-Spermidine inemisebenzi ebalulekile ye-antioxidant, futhi ingaba nemiphumela emikhulu yokulwa nokuguga ngokusebenzisa izakhiwo zayo ze-antioxidant. Ucwaningo luye lwabonisa ukuthi i-spermidine inganciphisa kakhulu amazinga e-oxidant malondialdehyde futhi ikhulise amazinga e-antioxidant enciphisa i-glutathione ebuchosheni bamagundane.
I-Spermidine supplementation iphinde yathuthukisa umsebenzi we-electron chain chain complexes ku-mitochondria yobuchopho obuguga, okubonisa amandla ayo e-antioxidant ezingeni le-mitochondrial. I-Spermidine inciphisa ukulimala kwemizwa ebangelwa ukuguga kwengcindezi ye-oxidative ngokulawula i-autophagy, amazinga e-antioxidant kanye nokunciphisa i-neuroinflammation.
Ucwaningo luthole ukuthi i-spermidine ivikela ukulimala kweseli okubangelwa i-H2O2 ngokuvimbela ukwanda kwe-Ca2+ kumaseli e-epithelial we-retinal pigment.
I-anti-inflammatory
I-Spermidine inomphumela omuhle wokulwa nokuvuvukala, futhi indlela yayo ihlobene nokuvimbela ukukhiqizwa kwezinto ezithinta ukuvuvukala, ukukhuthaza ukukhiqizwa kwezinto ezilwa nokuvuvukala, nokuthinta i-polarization yama-macrophages.
Ucwaningo luthole ukuthi i-spermidine inganciphisa amazinga ezici ezibangela ukuvuvukala njenge-interleukin 6 kanye ne-tumor necrosis factor ku-serum yamagundane ane-collagen-induced arthritis, ikhulise izinga le-IL-10, ivimbele ukuhlukaniswa kwe-M1 macrophages kuzicubu ze-synovial. , futhi unciphise ingozi yesifo sokuqaqamba kwamalunga. Amaseli e-synovial egundane ayanda futhi amangqamuzana okuvuvukala angena, abonisa imiphumela emihle yokulwa nokuvuvukala.
Thuthukisa ukuqonda
Njengoba inani labantu likhula, ukukhubazeka kwengqondo okuhlobene neminyaka kuya kuba yinkinga ecindezelayo. I-Spermidine, njenge-autophagy inducer, iboniswe ukuthi inomphumela wokuvuselela ekwehleni kwengqondo.
Ucwaningo lubonisa ukuthi ekugugeni kwezithelo ezimpukane, amazinga e-spermidine ayancipha, okuhambisana nokuncipha kwekhono lenkumbulo. I-Spermidine supplementation ephakelwa izimpukane inciphisa ukukhubazeka kwenkumbulo ezimpukaneni eziguga ngokuvimbela izinguquko zesakhiwo nokusebenza kwe-presynaptic okubangelwa amazinga aphakeme amaprotheni e-synaptic kanye namaprotheni abophayo.
I-Spermidine ekudleni ingadlula kumgoqo wegazi-wobuchopho wamagundane, ikhulise ukuphefumula kwe-mitochondrial kuzicubu ze-mouse neuron, futhi ithuthukise umsebenzi wokuqonda wamagundane. Ngokwesisekelo sokuhlolwa kwezilwane, ezinye izifundo zabantu ziye zafakazela ukuthi i-spermidine ihlobene eduze nokwazi.
Vikela inhliziyo nemithambo yegazi
I-Spermidine ingavikela impilo yenhliziyo nemithambo yegazi futhi inemiphumela eminingi njengokuvimbela ukuguga kwenhliziyo, ukunciphisa umfutho wegazi ophakeme nokubambezeleka kokuhluleka kwenhliziyo. Ucwaningo luye lwabonisa ukuthi ukwesekwa kwe-spermidine kungathuthukisa i-autophagy yenhliziyo kanye ne-mitophagy kumagundane, kube nomphumela we-cardioprotective futhi kubambezele ukuguga kwenhliziyo.
Emagundaneni asebekhulile, i-dietary spermidine supplementation ithuthukisa ukunwebeka kwemishini kanye nezakhiwo ze-metabolic ze-cardiomyocytes, ngaleyo ndlela yandise isikhathi sokuphila futhi ivimbele ukukhula kwe-hypertrophy yenhliziyo nokuqina. Izifundo ze-Epidemiological kubantu ziphakamisa ukuthi i-spermidine inemiphumela efanayo yokuvikela empilweni yabantu yenhliziyo. Ukungena kwe-Spermidine ekudleni komuntu kuhlotshaniswa ngokuphambene nesifo senhliziyo. Lezi zakhiwo ze-spermidine zivula izindlela ezintsha zokwelapha izifo zenhliziyo.
Isimo samanje sokuthuthukiswa nokusetshenziswa kwe-spermidine
I-Spermidine iyi-polyamine eyenzeka ngokwemvelo. Okuqukethwe kwe-physiological ye-spermidine kungokwemvelo, kusebenza kahle, kuphephile futhi akunabuthi. Ngokucwaninga okujulile kwemiphumela ye-spermidine eyengeziwe ye-physiological, ibonise ukubaluleka kwesicelo esibalulekile emikhakheni eminingi efana nemithi, ukudla kwezempilo, ezolimo, izimonyo nokunye.
Umuthi
I-Spermidine inemiphumela ehlukahlukene yomzimba efana nokuguga, ukulwa nokuvuvukala, ukulwa nomdlavuza, nokuthuthukisa ukuqonda. Ingasetshenziselwa ukuvimbela nokwelashwa kwe-osteoarthritis, ukulimala kwamangqamuzana ezinzwa, isifo senhliziyo nemithambo yegazi nezinye izifo. I-Spermidine isetshenziselwa izicelo zomtholampilo. Ukwelashwa kwezifo kunamathuba amahle okuthuthuka.
Ukudla okunempilo
Ukusebenzisa "i-spermidine" kanye "nezinto zokusetshenziswa zokudla ezisebenzayo" njengamagama angukhiye wokwenza ukusesha kwedatha kudathabhethi eminingi, imiphumela ibonisa ukuthi "i-spermidine" noma "i-spermine" ichazwa njengezinto zokusetshenziswa zokudla ezisebenzayo, kanti i-spermidine idayiswe emakethe nge-spermidine. . Ukudla okunempilo okune-amine njengento eyinhloko eluhlaza.
Imikhiqizo yezempilo ehlobene ne-Spermidine inemisebenzi ehlukahlukene futhi isetshenziswa kabanzi ngezindlela ezahlukahlukene, kufaka phakathi amaphilisi, izimpushana namanye amafomu omthamo. Inemisebenzi yokulwa nokuguga, ukuthuthukisa ukulala, nokuthuthukisa amasosha omzimba; i-powder yokudla ye-spermidine yemvelo ekhishwe egciwaneni likakolweni iqinisekisa ukuhlanzeka okuphezulu kanye nomsebenzi ophezulu we-spermidine.
Ezolimo
Njengesilawuli sokukhula kwesitshalo, ukusetshenziswa kwangaphandle kwe-spermidine kunganciphisa ngempumelelo umonakalo ezitshalweni ezibangelwa ukucindezeleka okufana nokushisa okuphezulu kwe-oxidation, izinga lokushisa eliphansi nokubanda, i-hypoxia, usawoti omningi, isomiso, izikhukhula nokungena emanzini, futhi idlala indima ebalulekile ekukhuleni kwezitshalo. . Iqhaza layo elibalulekile kwezolimo liye ladonsa amehlo kancane kancane. I-Exogenous spermidine ingadambisa umphumela ovimbelayo wengcindezi yesomiso ekukhuleni kwamabele amnandi futhi ithuthukise ukubekezelela isomiso kwezithombo zamabele amnandi. Ngokusekelwe endimeni ebalulekile ye-spermidine ekukhuleni kwezitshalo, inamalungelo obunikazi amaningi okusungula emkhakheni wezolimo. Ukucwaninga nokuthuthukisa imikhiqizo yezolimo ye-spermidine kanye nokukhuthaza ukusetshenziswa kwe-spermidine emkhakheni wezolimo kubaluleke kakhulu ekuthuthukisweni kwezolimo.
Izimonyo
I-Spermidine ine-antioxidant, anti-aging, kanye nokukhuthazwa kwemiphumela ye-autophagy, futhi iyimpahla enhle yezimonyo. Njengamanje, kunemikhiqizo yokunakekelwa kwesikhumba efana ne-spermidine anti-aging cream kanye ne-spermidine essence milk emakethe. Ngaphezu kwalokho, i-spermidine inamalungelo obunikazi amaningi ocwaningo emkhakheni wezimonyo emhlabeni jikelele, okubandakanya ukumhlophe, ukulwa nokuguga kwesikhumba, kanye nokwenza ngcono imibimbi yobuso. Ucwaningo olunzulu mayelana nendlela yokusebenza kwe-spermidine, ukucebisa amafomu ayo okufaka isicelo, nokuhlola ukuphepha nemiphumela emibi kulindeleke ukuthi kunikeze abathengi izinketho eziphephile nezisebenzayo zokunakekelwa kwesikhumba.
Kubantu, amazinga ajikelezayo wei-spermidine ngokuvamile zisebangeni eliphansi le-micromolar, cishe ngenxa yemiphumela yokudla ekugxilweni kwe-spermidine jikelele. Nakuba bebonisa umehluko oqinile phakathi kwabantu ngabanye. Kodwa-ke, njengoba sikhula, inani le-spermidine emangqamuzaneni omzimba wethu liyancipha. I-Exogenous spermidine supplementation ibuyisela emuva izinguquko ezimbi ezihlobene nobudala futhi ibambezele ukuguga.
● I-Prescine/spermine metabolism
Emaseli ezilwane ezincelisayo, i-spermidine ikhiqizwa kusukela ku-precursor putrescine (ngokwayo ekhiqizwa i-ornithine) noma ngokuwohloka kwe-oxidative ye-spermine.
●I-Gut microbiota
I-microbiota yamathumbu ingumthombo obalulekile we-spermidine synthesis. Emagundaneni, ukugxila kwe-spermidine ku-lumen yamathumbu kuye kwaboniswa ukuthi kuncike ngokuqondile ku-colonic microbiota.
●Imithombo yokudla
I-Spermidine efakwe ekudleni ingangena ngokushesha emathunjini futhi isatshalaliswe emzimbeni, ngakho-ke ukudla ukudla okune-spermidine kungasiza ukwandisa amazinga e-spermidine emzimbeni.
● Izithako ze-Spermidine
Imikhiqizo yezempilo ehlobene ne-Spermidine inemisebenzi ehlukahlukene futhi isetshenziswa kabanzi ngezindlela ezahlukahlukene, kufaka phakathi amaphilisi, izimpushana namanye amafomu omthamo. Inemisebenzi yokulwa nokuguga, ukuthuthukisa ukulala, nokuthuthukisa amasosha omzimba; i-powder yokudla ye-spermidine yemvelo ekhishwe egciwaneni likakolweni iqinisekisa ukuhlanzeka okuphezulu kanye nomsebenzi ophezulu we-spermidine.
Ubumsulwa kanye Nekhwalithi
Uma uthenga i-spermidine powder, kubalulekile ukubeka phambili ukuhlanzeka nekhwalithi. Bheka imikhiqizo eyenziwe ngezithako zekhwalithi ephezulu futhi ihlolwe ngokuqinile ukuhlanzeka nokusebenza. Ngokufanelekile, khetha imikhiqizo eyenziwe ezimbonini ezilandela Imikhuba Emihle Yokukhiqiza (GMP) ukuze uqinisekise ikhwalithi nokuphepha.
I-Bioavailability
I-Bioavailability isho ikhono lomzimba lokumunca nokusebenzisa into ethile. Uma ukhetha i-spermidine powder, cabanga nge-bioavailability yomkhiqizo. Bheka ifomula eklanyelwe ukumunca kahle, njengoba lokhu kuzoqinisekisa ukuthi umzimba wakho ungasebenzisa ngempumelelo i-spermidine ukuletha izinzuzo zayo zezempilo ezingaba khona.
Ukungafihli nokuhlola okuvela eceleni
Inqubo yokuhlonza nokukhiqiza impushana ehlonishwayo ye-spermidine kufanele ibe sobala. Bheka amabhrendi ahlinzeka ngolwazi oluningiliziwe mayelana nokutholakala kwezithako zawo kanye nokukhiqizwa kwemikhiqizo yawo. Ukwengeza, ukuhlolwa komuntu wesithathu okwenziwa ilabhorethri ezimele kuqinisekisa ikhwalithi yomkhiqizo nobumsulwa. Bheka imikhiqizo ehlolwe izinhlangano zezinkampani zangaphandle ukuze uqinisekise ukusebenza kahle nokuphepha kwayo.
Umthamo kanye Nosayizi Wokukhonza
Lapho uthenga i-spermidine powder, cabangela umthamo nosayizi wokuphakela ohambisana nezidingo zakho. Eminye imikhiqizo ingase inikeze ukugcwala okuphezulu kwe-spermidine ngokuphakelwa ngakunye, kuyilapho eminye imikhiqizo inganikeza umthamo ophansi. Kubalulekile ukunquma umthamo ofanele ngokusekelwe ezinhlosweni zakho zezempilo futhi uthintane nochwepheshe bezempilo lapho kudingeka.
Iresiphi kanye nezithako ezengeziwe
I-Spermidine powder itholakala ngezindlela ezihlukahlukene zemithamo, kufaka phakathi i-capsule, i-powder noma ifomu le-liquid. Cabangela ukuthi iyiphi ifomethi evumelana kangcono nendlela yakho yokuphila nezintandokazi zakho. Ukwengeza, eminye imikhiqizo ingase ibe nezithako ezengeziwe zokuthuthukisa imiphumela ye-spermidine noma ukuthuthukisa ukunambitheka kwayo. Naka noma yiziphi izithako ezingeziwe futhi uqiniseke ukuthi zihlangabezana nezintandokazi zakho zokudla kanye nemikhawulo.
Ukubuyekezwa kwekhasimende nesithunzi
Ngaphambi kokuthenga, zinike isikhathi sokucwaninga isithunzi somkhiqizo futhi ufunde izibuyekezo zekhasimende. Bheka impendulo evela kubantu abathile abasebenzise umkhiqizo ukuze uthole ukuqonda mayelana nokusebenza kwawo kanye nanoma yimiphi imiphumela emibi engaba khona. Imikhiqizo enegama elihle kanye nokubuyekezwa okuhle kwamakhasimende kungenzeka ukuthi inikeze okuthembekile kanye nekhwalithi ephezulu ye-spermidine powder.
Inani uma liqhathaniswa nenani
Nakuba intengo kungafanele kube yiyona kuphela into enqumayo, kubalulekile ukucabangela inani lomkhiqizo ngokuhlobene nenani lawo. Qhathanisa izindleko zezimpushana ze-spermidine futhi ucabangele ikhwalithi, ubumsulwa, kanye nezinzuzo ezengeziwe zomkhiqizo ngamunye. Ukutshala imali ku-powder ye-spermidine ephezulu kungase kunikeze izinzuzo ezinkulu zezempilo ezingase zibe khona.
I-Suzhou Myland Pharm's Spermidine Powder—Isengezo sokudla sekhwalithi ephezulu
KwaSuzhou Myland Pharm, sizibophezele ekuhlinzekeni ngemikhiqizo esezingeni eliphezulu ngamanani angcono kakhulu. I-spermidine powder yethu ihlolwe ngokuqinile ukuhlanzeka namandla, iqinisekisa ukuthi uthola isengezo sekhwalithi ephezulu ongayethemba. Kungakhathaliseki ukuthi ufuna ukusekela impilo yeselula, ukuqinisa amasosha akho omzimba noma ukuthuthukisa impilo yonke, i-spermidine powder yethu iyisinqumo esihle kakhulu.
Njengoba inesipiliyoni seminyaka engu-30 futhi iqhutshwa ubuchwepheshe obuphezulu kanye namasu e-R&D athuthukiswe kakhulu, iSuzhou Myland Pharm isungule uhide lwemikhiqizo encintisanayo futhi yaba isithasiselo sesayensi yempilo emisha, ukuhlanganisa ngokwezifiso kanye nenkampani yezinkonzo zokukhiqiza.
Ngaphezu kwalokho, iSuzhou Myland Pharm iphinde ibe ngumkhiqizi obhalisiwe we-FDA. Izinsiza ze-R&D zenkampani, izindawo zokukhiqiza, namathuluzi okuhlaziya kungokwesimanjemanje futhi kunemisebenzi eminingi, futhi ingakhiqiza amakhemikhali ukusuka kuma-milligrams kuye kumathani esikalini, futhi ithobelane namazinga e-ISO 9001 kanye nokucaciswa kokukhiqiza kwe-GMP.
Q: Iyini i-spermidine powder futhi ihlobene kanjani nokuguga?
A: I-Spermidine iyinhlanganisela yemvelo ye-polyamine etholakala ekudleni okuhlukahlukene kanye nomzimba womuntu. Ucwaningo lubonisa ukuthi i-spermidine ingaba nemiphumela yokulwa nokuguga ngokukhuthaza impilo yeselula nokuphila isikhathi eside.
Q: Ngabe i-spermidine powder isebenza kanjani ukulwa nokuguga?
A:I-Spermidine kukholakala ukuthi yenza kusebenze inqubo yeselula ebizwa ngokuthi i-autophagy, esiza ukususa amaseli awonakele futhi ikhuthaze ukuvuselelwa kwamaseli anempilo. Le nqubo kucatshangwa ukuthi idlala indima ebalulekile ekubambezeleni inqubo yokuguga.
Q: Yiziphi izinzuzo ezingaba khona zokuthatha i-spermidine powder yokuguga?
A: Ezinye izifundo zibonise ukuthi ukwesekwa kwe-spermidine kungasiza ekuthuthukiseni impilo yenhliziyo, ukusebenza kobuchopho, nokuphila isikhathi eside. Kungase futhi kube nezinzuzo ezingaba khona empilweni yesikhumba nokusebenza komzimba wokuzivikela komzimba.
Q: Ngingaqinisekisa kanjani ikhwalithi ye-spermidine powder lapho ngiyithenga ku-intanethi?
IMP: Funa umphakeli ohlonishwayo nozinzile onomlando wokuhlinzeka ngezithasiselo zokudla ezisezingeni eliphezulu. Hlola ukubuyekezwa kwekhasimende nezilinganiso ukuze ulinganise ukwethembeka komnikezeli.
Umshwana wokuzihlangula: Lesi sihloko esolwazi oluvamile kuphela futhi akufanele sithathwe njengeseluleko sezokwelapha. Olunye ulwazi lokuthunyelwe kwebhulogi luvela ku-inthanethi futhi alusebenzi. Le webhusayithi inomthwalo wemfanelo kuphela wokuhlunga, ukufometha kanye nokuhlela ama-athikili. Injongo yokudlulisa ulwazi olwengeziwe ayisho ukuthi uyavumelana nemibono yayo noma uqinisekise ubuqiniso bokuqukethwe kwayo. Hlala uthintana nochwepheshe bezempilo ngaphambi kokusebenzisa noma yiziphi izithasiselo noma wenze izinguquko ohlelweni lwakho lokunakekelwa kwezempilo.
Isikhathi sokuthumela: Aug-28-2024
