Ezweni elikhulayo lezithako zokudla, i-magnesium alpha-ketoglutarate powder ithola ukunakwa ngezinzuzo zayo ezingaba khona. I-Alpha-ketoglutarate (AKG) iyinhlanganisela eyenzeka ngokwemvelo emzimbeni edlala indima ebalulekile kumjikelezo we-Krebs, obalulekile ekukhiqizeni amandla. Uma ihlanganiswa ne-magnesium, i-mineral ebalulekile eyaziwa ngezinzuzo zayo eziningi zezempilo, le powder iba isengezo esinamandla. I-Magnesium ibandakanyeka ekuphenduleni kwamakhemikhali angaphezu kwama-300 emzimbeni, okuhlanganisa ukusebenza kwemisipha, ukuhanjiswa kwe-neurotransmission kanye nempilo yamathambo.
I-Alpha-ketoglutarate (i-AKG ngamafuphi), eyaziwa nangokuthi i-2-oxoglutarate (2-OG), idlala indima ebalulekile ezinqubweni zebhayoloji ze-energy metabolism kanye nokuhlanganiswa kwe-amino acid. Akugcini nje ngokujula enqubweni ye-oxidation yama-fatty acids, ama-amino acid kanye ne-glucose, kodwa futhi iwumkhiqizo omaphakathi womjikelezo we-tricarboxylic acid (TCA) ochungechungeni lokuphefumula, olubalulekile ekunikezeni amandla ayisisekelo ukuze kugcinwe ukuphila. imisebenzi.
Eminyakeni yamuva nje, ucwaningo lwesayensi lwembule ukuthi i-AKG iyisici esinamandla sokulwa nokuguga. Inemiphumela ebalulekile ekwandiseni ubude besikhathi sokuphila kanye nokuthuthukisa impilo ngokulawula ngokunembile imisebenzi ehlukahlukene yokuphila komzimba wezinto eziphilayo.
I-AKG ayiwona nje kuphela umthombo wamandla obalulekile wamangqamuzana asemathunjini ukuze akhiqize i-adenine nucleoside triphosphate (ATP), kodwa futhi idlala indima ebalulekile njengesandulela sama-amino acid abalulekile njenge-glutamate, glutamine ne-arginine.
Ucwaningo lwesayensi lukhombisa ngokusobala ukuthi i-AKG ingakhuthaza ngokuqondile noma ngokungaqondile inqubo yokuhlanganiswa kwama-amino acid futhi idlala indima ebalulekile ekugcineni ibhalansi yama-amino acid emzimbeni. Kodwa-ke, inani le-AKG elikhiqizwa ngesikhathi semetabolism yemvelo yamaseli ukuze ahlanganise ama-amino acid adingekayo ngokuvamile kunzima ukuhlangabezana nezidingo zomzimba. Ngakho-ke, kubaluleke kakhulu ukwengeza i-AKG ngokusebenzisa izindlela zokudla.
I-alpha-ketoglutarate (AKG) iyilula kanjani impilo?
I-Alpha-ketoglutarate isiza ukwakheka kwemisipha, ipholise amanxeba, inciphise ukuvuvukala, nezinye izindlela eziningi zokubambezela inqubo yokuguga:
I-α-Ketoglutarate iyi-molecule yokuphila isikhathi eside enganweba isikhathi sokuphila sezinto ezihlukahlukene eziphilayo (njenge-Caenorhabditis elegans, i-Drosophila melanogaster, namagundane). I-α-Ketoglutarate (AKG) inemiphumela ehlukahlukene ezindleleni ezihlukahlukene zokuguga (njenge-Table Epigenetics kanye nokungasebenzi kahle kwe-mitochondrial) kunenzuzo.
Kuphinde kube yinto engokwemvelo etholakala emzimbeni, nokho, amazinga ayo ehla ngokukhula. Isiza umzimba ukuthi ukhiphe ubuthi futhi usize umzimba ukuthi ukhiphe i-ammonia, okuwukungcola okukhiqizwa yi-protein metabolism futhi ekwazi ukunqwabelana kalula emzimbeni (uma udla amaprotheni amaningi, kukhiqizwa i-ammonia eyengeziwe).
Njengoba sikhula, kuba nzima kakhulu ukuthi umzimba ukhiphe i-ammonia. I-ammonia eningi iyingozi emzimbeni. I-Alpha-ketoglutarate isiza umzimba ukuthi ukhiphe ubuthi futhi uqede izinto eziyingozi.
Ithuthukisa impilo ye-mitochondrial futhi ingasebenza njengophethiloli we-mitochondria
Le nto futhi ingenye yemithombo yamandla ye-mitochondria futhi ingavula i-AMPK, i-metabolism ebalulekile ehlobene nokuphila isikhathi eside.
Iphinde inikeze amandla engeziwe nokukhuthazela, yingakho abanye abasubathi nabakhi bomzimba bethatha izithasiselo ze-alpha-ketoglutarate isikhathi eside.
Okuhle kunakho konke ukuthi iphephe kakhulu, i-AKG iyingxenye yomjikelezo we-metabolic lapho amaseli ethu ethola khona amandla ekudleni.
Ilawula ukwakheka kwamaprotheni nokuthuthukiswa kwamathambo
I-Alpha-ketoglutarate nayo idlala indima ekugcineni impilo ye-stem cell, kanye ne-bone kanye ne-intestinal metabolism. Kumetabolism yamaselula, i-AKG iwumthombo obalulekile we-glutamine ne-glutamate, evuselela ukwakheka kwamaprotheni, ivimbele ukuwohloka kwamaprotheni emisipha, futhi yakha uphethiloli obalulekile we-metabolic wamangqamuzana amathumbu.
I-Glutamine iwumthombo wamandla wazo zonke izinhlobo zamangqamuzana ezinto eziphilayo, ibalwa ngaphezu kuka-60% wesamba se-amino acid pool. Ngakho-ke, i-AKG, njengesandulela se-glutamine, iwumthombo wamandla oyinhloko wama-enterocyte kanye ne-substrate ekhethwayo yama-enterocyte.
Magnesium
I-Magnesium iyiminerali ebalulekile edlala izindima eziningi emzimbeni. Ihileleke ekuphenduleni kwe-enzymatic okungaphezu kuka-300, okuhlanganisa nalokho okuhlobene nokukhiqizwa kwamandla, ukuhlanganiswa kwamaprotheni, nokusebenza kwemisipha. I-Magnesium isiza futhi ukugcina ukusebenza kwemizwa evamile, amazinga kashukela egazini, nokulawula umfutho wegazi. Naphezu kokubaluleka kwe-magnesium, abantu abaningi abahlangabezani nokudla okunconyiwe kwansuku zonke kwe-magnesium, okuholela ekuntuleni okungaba khona kwe-magnesium okuthinta impilo yonke.
I-Alpha-ketoglutarate
I-Alpha-ketoglutarate (AKG) iyinhlanganisela eyenzeka ngokwemvelo edlala indima ebalulekile kumjikelezo we-Krebs, obalulekile ekuphefumuleni kwamaselula kanye nokukhiqizwa kwamandla. Iphinde ibandakanye ku-amino acid metabolism kanye ne-neurotransmitter synthesis. I-AKG iye yafundelwa izinzuzo zayo ezingaba khona ezimweni zezempilo ezihlukahlukene, okuhlanganisa indima yayo ekukhuthazeni ukululama kwemisipha, ukuthuthukisa ukusebenza kahle kwezemidlalo, kanye nokusekela impilo ye-metabolic.
Umphumela we-synergistic we-magnesium ne-alpha-ketoglutarate
I-Magnesium alpha-ketoglutarate iyinhlanganisela ehlanganisa i-magnesium ne-alpha-ketoglutarate, ukhiye omaphakathi emjikelezweni we-Krebs (owaziwa nangokuthi umjikelezo we-citric acid), obalulekile ekukhiqizeni amandla kwamaseli kubalulekile.
Lapho i-magnesium ihlanganiswa ne-alpha-ketoglutarate, inhlanganisela ewumphumelai-magnesium alpha-ketoglutarate inenani lezinzuzo eziyingqayizivele. Umphumela we-synergistic phakathi kwe-magnesium ne-AKG uthuthukisa i-bioavailability yazo zombili izithako, okwenza kube lula ngomzimba ukuthi uzimunce futhi uzisebenzise ngempumelelo. Le nhlanganisela ikhanga ikakhulukazi kubasubathi nakubantu abafuna ukuthuthukisa ukusebenza ngokomzimba nokululama.
I-Magnesium alpha-ketoglutarate ivame ukusetshenziswa njengesengezo sokudla, ikakhulukazi kubantu abafuna ukukhulisa amazinga wamandla, ukuthuthukisa ukululama, noma ukusekela impilo yonke.
1. I-Creatine
Uhlolojikelele: I-Creatine ingesinye sezithako ezicwaningwe kakhulu embonini yokufaneleka, eyaziwa ngamandla ayo okwakha amandla nesisindo semisipha.
Ukuqhathanisa: Nakuba i-creatine ngokuyinhloko igxile ekwandiseni amandla nobukhulu bemisipha, i-magnesium alpha ketoglutarate powder inikeza izinzuzo ezibanzi ze-metabolic, okuhlanganisa ukukhiqizwa kwamandla nokululama. Kubasubathi abafuna amandla okuqhuma, i-creatine ingaba inketho yokuqala, kodwa kubasubathi abafuna ukusekelwa okuphelele kwe-metabolic, i-AKG ene-magnesium ingase ibe yinzuzo enkulu.
2. I-BCAA (ama-amino acid ochungechunge olunegatsha)
Uhlolojikelele: Ama-amino acid e-branched-chain adumile phakathi kwabasubathi ngeqhaza lawo ekululameni kwemisipha kanye nokunciphisa ubuhlungu bemisipha obubangelwa ukuvivinya umzimba.
Ukuqhathanisa: Ama-amino acid e-branched-chain asebenza kahle ekubuyiseleni imisipha, kodwa awanikezi ukusekelwa okufanayo kwe-metabolic njenge-AKG. Nakuba i-branched-chain amino acids isiza ekulungiseni imisipha, i-magnesium alpha ketoglutarate powder ithuthukisa ukukhiqizwa kwamandla kanye nokululama jikelele, okwenza kube inketho enhle kakhulu kulabo abafuna ukuthuthukisa ukusebenza nokululama.
3. L-carnitine
Uhlolojikelele: I-L-carnitine ijwayele ukusetshenziselwa ukunciphisa amafutha nokuthuthukisa ukusebenza kwezemidlalo ngokugqugquzela ukuthutha okunamafutha acid ku-mitochondria ukuze kukhiqizwe amandla.
Ukuqhathanisa: I-L-Carnitine ne-AKG Magnesium Powder zombili zisekela i-metabolism yamandla, kodwa lokhu zikwenza ngezindlela ezahlukene. I-L-Carnitine igxile kakhulu ku-fat oxidation, kuyilapho i-AKG inikeza izinzuzo ezibanzi ezihlanganisa ukululama kwemisipha nokusekelwa kwengqondo. Kulabo abafuna ukuthuthukisa ukulahlekelwa kwamafutha ngenkathi besekela impilo yemisipha, inhlanganisela yakho kokubili ingase ibe ekahle.
4.Omega-3 fatty acids
Uhlolojikelele: Ama-Omega-3 aziwa ngezakhiwo zawo zokulwa nokuvuvukala kanye nezinzuzo ezithinta inhliziyo.
Ukuqhathanisa: I-Omega-3 igxile ekunciphiseni ukuvuvukala nokusekela impilo yenhliziyo, kuyilapho i-Magnesium Alpha Ketoglutarate powder igxile ekukhiqizeni amandla nokululama kwemisipha. Kubantu abafuna ukuthuthukisa impilo yabo yonke, ukuhlanganisa lezi zithako ezimbili kunikeza indlela ebanzi.
5.Ama-Multivitamins
Uhlolojikelele: Ama-Multivitamins aklanyelwe ukugcwalisa izikhala zokudla okunomsoco ekudleni, ahlinzeke ngohlu lwamavithamini namaminerali abalulekile.
Qhathanisa: Nakuba ama-multivitamins ehlinzeka ngohlu olubanzi lwemisoco, angase anganikezi izinzuzo ezithile ze-AKG ne-magnesium. Kulabo abagxile ekukhiqizeni amandla kanye nokubuyiswa kwemisipha, i-magnesium alpha ketoglutarate powder ingase ibe inketho ehlosiwe kakhudlwana.
1. Ukuthuthukisa ukukhiqizwa kwamandla
Enye yezinzuzo eziphambili zeMagnesium Alpha Ketoglutarate Powder indima yayo ekukhiqizeni amandla. I-Alpha-ketoglutarate iyisihluthulelo esimaphakathi kumjikelezo we-Krebs, inqubo imizimba yethu eguqula ngayo ama-carbohydrate, amafutha, namaprotheni abe amandla. Ngokufaka i-AKG, uthuthukisa ikhono lomzimba wakho lokukhiqiza amandla ngokuphumelelayo. I-Magnesium, ngakolunye uhlangothi, iyiminerali ebalulekile edlala indima ebalulekile ekuphenduleni kwe-enzymatic okungaphezu kwama-300 emzimbeni, okuhlanganisa nalabo ababandakanyeka kumetabolism yamandla. Uma kusetshenziswe ndawonye, i-AKG ne-magnesium zisebenza ngokubambisana ukuze kuthuthukiswe ukukhiqizwa kwamandla.
2. Thuthukisa ukululama kwemisipha
I-AKG ikhonjiswe ukusiza ukunciphisa ukuwohloka kwemisipha kanye nokusekela ukuhlanganiswa kwamaprotheni, okubalulekile ekulungiseni nasekukhuleni kwemisipha. Ukwengeza, i-magnesium yaziwa ngezakhiwo zayo zokuphumula imisipha. Kuyasiza ukuvimbela ama-cramps nama-spasms, okwenza inqubo yokutakula ibe bushelelezi. Ngokufaka i-Magnesium Alpha Ketoglutarate Powder ohlelweni lwakho lwangemva kokujima, unganciphisa ubuhlungu bemisipha futhi ubuyele ekusebenzeni okuphezulu ngokushesha.
3. Thuthukisa ukusebenza kwengqondo
Ucwaningo lubonisa ukuthi i-AKG ingakwazi ukusekela impilo yobuchopho ngokukhuthaza ukukhiqizwa kwama-neurotransmitters kanye nokuthuthukisa i-synaptic plasticity, okubalulekile ekufundeni nasekukhumbuleni. I-Magnesium nayo idlala indima ebalulekile ekusebenzeni kwengqondo. Kuye kwaxhunyaniswa nemizwa ethuthukisiwe, ukunciphisa ukukhathazeka, kanye nempilo yobuchopho ethuthukisiwe. Ngokuhlanganisa i-AKG ne-magnesium, isipiliyoni sandise ukucaca kwengqondo, ukugxilisa ingqondo, kanye nekhono elithuthukisiwe lokulawula ingcindezi.
4. Sekela ukuguga okunempilo
Njengoba sikhula, imizimba yethu iba nezinguquko ezihlukahlukene ezingase zithinte impilo yethu yonke kanye nokuphila kahle. I-Alpha-ketoglutarate ithole ukunakwa ngezindawo zayo zokulwa nokuguga ezingase zibe khona. Ezinye izifundo ziphakamisa ukuthi i-AKG ingasiza ukunweba ubude besikhathi sokuphila ngokusekela impilo yeseli kanye nokunciphisa ingcindezi ye-oxidative. I-Magnesium ibalulekile futhi ekugcineni ukuguga okunempilo. Kuyasiza ukulawula imisebenzi ehlukahlukene yomzimba, okuhlanganisa umfutho wegazi, ukusebenza kwemisipha, nempilo yamathambo. Ngokuhlanganisa i-AKG ne-magnesium, ungase ukwazi ukusekela inqubo yokuguga yemvelo yomzimba wakho, ukwandisa amandla kanye nokuphila kahle njengoba ukhula.
5. Impilo Yamathumbu kanye Nokwesekwa Kokugaya Ukudla
Impilo yamathumbu iyisisekelo sempilo yonke, futhi i-magnesium alpha ketoglutarate powder ingase ibambe iqhaza ekusekeleni uhlelo olunempilo lokugaya ukudla. I-AKG ikhonjiswe ukuthi inemiphumela enenzuzo ku-gut microbiome, ikhuthaza ukukhula kwamabhaktheriya anenzuzo ngenkathi icindezela izinhlobo eziyingozi. Lokhu kubangela ukugaya okuthuthukisiwe kanye nokumuncwa okungcono kwezakhi. I-Magnesium isiza futhi empilweni yokugaya ukudla ngokusiza ukulawula ukunyakaza kwamathumbu nokuvimbela ukuqunjelwa. Iphumuza izicubu zomgudu wokugaya ukudla futhi ikhuthaze ukugayeka kokudla kahle.
1. Ubumsulwa kanye Nekhwalithi
Lapho ukhetha i-supplement, ubumsulwa bubalulekile. Bheka imikhiqizo engenawo ama-filler, imibala yokwenziwa kanye nama-preservatives. Ikhwalithi ephezulu ye-magnesium alpha ketoglutarate powder kufanele ibe nenani eliphezulu lezithako ezisebenzayo. Hlola izitifiketi zokuhlola zezinkampani zangaphandle ukuze uqinisekise ukuthi imikhiqizo ihlolelwe ubumsulwa namandla.
2. Umthombo wezinto zokusetshenziswa
Umthombo wezithako ungathinta kakhulu ikhwalithi yesithasiselo sakho. Cwaninga umenzi ukuze uqiniseke ukuthi basebenzisa i-AKG yekhwalithi ephezulu, etholakala nge-bioavailable kanye ne-magnesium. Futhi cabanga ukuthi izithako zivela emithonjeni yemvelo noma zenziwa elebhu.
3. Umthamo kanye nokugxilisa ingqondo
Imikhiqizo ehlukene ingase iqukathe ukugxilisa okuhlukene kwe-AKG ne-magnesium. Qiniseka ukuthi uhlola umthamo ngamunye kulebula ukuze uqiniseke ukuthi uhlangabezana nemigomo yakho yezempilo. Umthamo onconyiwe ungahluka ngokuya ngezidingo zomuntu ngamunye, ngakho-ke kunconywa ukuthi ubonane nochwepheshe bezempilo ngaphambi kokuqala noma yiziphi izithasiselo ezintsha.
4. Ukwakhiwa kanye nezithako ezengeziwe
Amanye ama-powders e-magnesium alpha ketoglutarate angase aqukathe ezinye izithako eziklanyelwe ukuthuthukisa ukumuncwa noma ukunikeza izinzuzo ezingeziwe. Isibonelo, amanye amafomula angase abe novithamini B6, ongasiza ukumuncwa kwe-magnesium. Kodwa-ke, qaphela ngemikhiqizo enezela izithako eziningi kakhulu njengoba ingenza ifomula ibe nzima futhi ingase ingadingeki ngezidingo zakho.
5. Idumela lomkhiqizo
Cwaninga imikhiqizo ngaphambi kokuthenga. Imikhiqizo eyaziwayo enedumela elihle kungenzeka ukuthi ikhiqize izithasiselo zekhwalithi ephezulu. Bheka ukubuyekezwa kwamakhasimende kanye nobufakazi ukuze ulinganise ulwazi lwabanye abantu. Amabhrendi asobala mayelana nokutholakala kwawo, izinqubo zokukhiqiza nokuhlola ngokuvamile athembeke kakhulu.
6. Iphuzu lentengo
Yize intengo kungafanele kube yiyona kuphela into enqumayo, ukuthola umkhiqizo olingana nesabelomali sakho kubalulekile. Qaphela izinketho ezinenani eliphansi kakhulu njengoba zingase zibeke engcupheni ikhwalithi. Qhathanisa izintengo zamabhrendi aziwayo ukuze uthole ibhalansi phakathi kwekhwalithi nokuthengeka.
I-Myland Pharm & Nutrition Inc. ibambe iqhaza ebhizinisini lesengezo sokudla okunempilo kusukela ngo-1992. Yinkampani yokuqala eShayina ukuthuthukisa nokudayisa imbewu yamagilebhisi.
Njengoba inesipiliyoni seminyaka engu-30 futhi iqhutshwa ubuchwepheshe obuphezulu kanye namasu e-R&D athuthukiswe kakhulu, inkampani ithuthukise uhla lwemikhiqizo encintisanayo futhi yaba isithasiselo sesayensi yempilo emisha, ukuhlanganisa ngokwezifiso kanye nenkampani yezinkonzo zokukhiqiza.
Ngaphezu kwalokho, i-Myland Pharm & Nutrition Inc. iphinde ibe ngumkhiqizi obhalisiwe we-FDA. Izinsiza ze-R&D zenkampani, izindawo zokukhiqiza, namathuluzi okuhlaziya kungokwesimanjemanje futhi kunemisebenzi eminingi, futhi ingakhiqiza amakhemikhali ukusuka kumamiligremu ukuya kumathani esikalini futhi ihambisane namazinga e-ISO 9001 kanye nemininingwane yokukhiqiza ye-GMP.
Q: Iyini i-Magnesium Alpha-Ketoglutarate Powder?
A:I-Magnesium Alpha-Ketoglutarate Powder iyisengezo sokudla esihlanganisa i-magnesium ne-alpha-ketoglutarate, inhlanganisela ehilelekile kumjikelezo we-Krebs, obalulekile ekukhiqizeni amandla emzimbeni. Lesi sengezo sivame ukusetshenziselwa ukusekela impilo ye-metabolic, ukuthuthukisa ukusebenza kwezemidlalo, nokukhuthaza inhlalakahle jikelele.
Q: Yiziphi izinzuzo zokuthatha i-Magnesium Alpha-Ketoglutarate Powder?
A:Ezinye izinzuzo ezingaba khona zeMagnesium Alpha-Ketoglutarate Powder zifaka:
● Ukukhiqizwa Kwamandla Okuthuthukisiwe: Isekela umjikelezo we-Krebs, isiza ekuguquleni izakhi zibe amandla.
● Ukubuyiselwa Kwemisipha: Kungase kusize ukunciphisa ubuhlungu bemisipha futhi kuthuthukise isikhathi sokululama ngemva kokuzivocavoca.
● Impilo Yamathambo: I-Magnesium ibalulekile ekugcineni amathambo enempilo futhi ingase isize ekuvimbeleni ukukhumuzeka kwamathambo.
Umsebenzi Wokuqonda: Ezinye izifundo ziphakamisa ukuthi zingase zisekele impilo yobuchopho nokusebenza kwengqondo.
● Ukusekelwa Kwe-Metabolic: Kungasiza ekulawuleni izinqubo ze-metabolic futhi kungasiza ekulawuleni isisindo.
Umshwana wokuzihlangula: Lesi sihloko esolwazi oluvamile kuphela futhi akufanele sithathwe njengeseluleko sezokwelapha. Olunye ulwazi lokuthunyelwe kwebhulogi luvela ku-inthanethi futhi alusebenzi. Le webhusayithi inomthwalo wemfanelo kuphela wokuhlunga, ukufometha kanye nokuhlela ama-athikili. Injongo yokudlulisa ulwazi olwengeziwe ayisho ukuthi uyavumelana nemibono yayo noma uqinisekise ubuqiniso bokuqukethwe kwayo. Hlala uthintana nochwepheshe bezempilo ngaphambi kokusebenzisa noma yiziphi izithasiselo noma wenze izinguquko ohlelweni lwakho lokunakekelwa kwezempilo.
Isikhathi sokuthumela: Oct-10-2024
