J-147 umkhiqizi we-powder CAS No.: 1146963-51-0 99.0% ubumsulwa min. okwengeza izithako
Amapharamitha womkhiqizo
| Igama lomkhiqizo | 2,2,2-Trifluoroacetic acid 1-(2,4-DiMethylphenyl)-2-[(3-Methoxyphenyl)Methylene]hydrazide] |
| Elinye igama | J-147, J147 |
| Inombolo ye-CAS. | 1146963-51-0 |
| Ifomula yamangqamuzana | I-C18H17F3N2O2 |
| Isisindo samangqamuzana | 350.33 |
| Ubumsulwa | 99% |
| Ukubukeka | Impushana emhlophe |
| Ukupakisha | 1kg isikhwama ngasinye |
| Isicelo | izidakamizwa ze-nootropic |
Isingeniso Somkhiqizo
I-J-147 iyi-neuroprotectant enamandla ikakhulukazi esebenza ngomlomo etholakala ngokuyinhloko ku-curcumin, isithako esisebenzayo ku-turmeric. Ngokungafani ne-curcumin, idlula umgoqo wegazi-ubuchopho ngempumelelo kakhulu. Phakathi kwazo, i-J-147 isebenza ngokubophezela ku-ATP synthase. Ukukhiqizwa ngokweqile kwe-ATP kuhlotshaniswa nenqubo yokuguga. Ngaphezu kwamazinga akhulayo ama-neurotransmitters NGF kanye ne-BDNF, i-J-147 ingakwazi ukulawula lokhu. Ngaphezu kwalokho, i-J-147 ivimbela i-monoamine oxidase B kanye ne-dopamine transporter. Ikhuthaza ukukhula kobuchopho ngokwandisa amazinga e-nerve growth factor (NGF) kanye ne-brain-derived neurotrophic factor (BDNF). Okubaluleke kakhulu, i-J-147 ingakhuthaza ukukhula kwamangqamuzana ezinzwa amasha, ithuthukise ikhono lokufunda lobuchopho nenkumbulo, futhi ithuthukise ukusebenza kwengqondo.
Isici
(1) Ukuhlanzeka okuphezulu: I-J-147 ingathola imikhiqizo ehlanzekile ngezinqubo zokukhiqiza zokucwenga. Ukuhlanzeka okuphezulu kusho i-bioavailability engcono kanye nokusabela okungekuhle okumbalwa.
(2) Ukuphepha: I-J-147 iye yafakazelwa ukuthi iphephile emzimbeni womuntu.
(3) Ukuzinza: I-J-147 inokuzinza okuhle futhi ingagcina umsebenzi wayo nomthelela ngaphansi kwezindawo ezihlukene nezimo zokugcina.
(4) Kulula ukumunca: I-J-147 ingamuncwa ngokushesha umzimba womuntu, ingene ekujikelezeni kwegazi emathunjini, futhi isakazwe ezicutshini nasezithweni ezihlukahlukene.
Izinhlelo zokusebenza
I-J-147 iyinhlanganisela yokwenziwa okusebenza kwayo okuyinhloko kuhilela ukuthuthukiswa kwe-mitochondrial, ngaleyo ndlela ithuthukise ukukhiqizwa kwamandla ezingeni lamaselula. I-J-147 yakhelwe ukuthuthukisa ikhono lobuchopho lokuzilungisa nokuzivikela emonakalweni ohlobene neminyaka ngokuthuthukisa ukusebenza kwe-mitochondrial. Ukwengeza, i-J-147 ibonisa izakhiwo ezibalulekile zokulwa nokuvuvukala kanye ne-antioxidant, ithuthukisa nakakhulu imiphumela yayo ye-neuroprotective engaba khona. I-J-147 ingakhuthaza ukukhula kwamangqamuzana ezinzwa amasha, ithuthukise ikhono lokufunda lobuchopho nenkumbulo, futhi ithuthukise ukusebenza kwengqondo.
