Ezweni lanamuhla elisheshayo, ukulondoloza indlela yokuphila enempilo kuya ngokuya kubaluleke kakhulu. Esinye sezihluthulelo zokuphila okunempilo ukulawula isisindo. Ukunqwabelana kwamafutha ngokweqile akuthinti nje kuphela ukubukeka kwethu kodwa futhi kusibeka engozini yezinkinga ezihlukahlukene zempilo. Nakuba ukudla okwehlayo kanye nokuzivocavoca umzimba okukhandlayo kungase kunikeze imiphumela esheshayo, ngokuvamile akuphumelelanga ukunikeza isisombululo esimeme. Izithako ezishisa amafutha zingasisiza ukuba sehlise isisindo esiningi futhi sibe nomzimba onempilo, ozacile.
Uma kuziwa ekwehliseni isisindo, abantu abaningi basebenzisa izindlela ezihlukene, kusukela ekunciphiseni isisindo kuya ekuzilolongeni. Nokho, isu elilodwa elisebenzayo elivame ukunganakwa lihlanganisa izithako ezishisa amafutha ekudleni kwethu kwansuku zonke. Lezi zithako zingasiza ukusheshisa imetabolism yethu futhi zikhuthaze ukuncipha kwesisindo.
Izithako ezishisa amafutha yizinto ezitholakale zikhuthaza ukuwohloka nokusetshenziswa kwamafutha agciniwe emzimbeni. Zitholakala ekudleni okuthile, amakhambi nezinongo futhi zaziwa ngamandla azo okuthuthukisa imetabolism, ukucindezela ukudla nokuthuthukisa i-oxidation yamafutha. Ngokungafani nalezi zithako ezishisa amafutha, izithako ezishisa amafutha ngokuvamile ziyizithako eziklanyelwe ukusheshisa inqubo yokulahlekelwa kwamafutha futhi zenziwe ngezithako zemvelo ezisiza ukukhulisa umzimba, ukucindezela ukudla, nokwandisa amazinga wamandla. Lezi zithako zenzelwe ukuthuthukisa amandla omzimba okushisa amafutha ngokukhomba izindlela ezahlukahlukene ngaphakathi kohlelo lwethu.
Isithako esisodwa esidumile sokushiswa kwamafutha yi-green tea extract. Itiye elihlaza liqukethe ama-catechin, i-antioxidant ekhonjisiwe ukusiza ukukhulisa umzimba nokukhuthaza ukulahleka kwamafutha. Ucwaningo luye lwathola ukuthi ukudla itiye eliluhlaza akhiphe kungakhuphula ukusetshenziswa kwekhalori kanye ne-oxidation yamafutha, okwenza kube isengezo esiwusizo kunoma yisiphi isimiso sokulahlekelwa isisindo.
Esinye isithako esinamandla esishisa amafutha i-capsaicin, evame ukutholakala kupelepele. I-Capsaicin inezici ze-thermogenic, okusho ukuthi inyusa izinga lokushisa lomzimba futhi ikhuphule imetabolism. Kutholakale futhi ukucindezela ukudla nokunciphisa ukudla kwe-caloric. Ukwengeza upelepele we-cayenne ekudleni kwakho noma ukuthatha isithako se-capsaicin kungasiza ukuqalisa uhambo lwakho olushisa amafutha.
Ngaphezu kwalezi zithako, kuye kwatholakala ukuthi amakhambi nezinongo ezithile zinezakhiwo ezishisa amafutha. Isibonelo, isinamoni iboniswe ukusiza ukulawula amazinga kashukela egazini, ngaleyo ndlela ivimbele ukugcinwa kwamafutha amaningi. I-Turmeric, ngakolunye uhlangothi, iqukethe i-curcumin, inhlanganisela etholakala ukusiza ukulahlekelwa isisindo ngokunciphisa ukuvuvukala nokuthuthukisa ukuzwela kwe-insulin.
Kubalulekile ukuqaphela ukuthi nakuba izithako ezishisa amafutha zingasiza ekunciphiseni isisindo, azisona isisombululo esiphelele. Ukuze uzuze ukulahlekelwa kwesisindo esimeme, ukudla okunempilo okunempilo, ukuvivinya umzimba njalo kanye nokufakwa kwe-hydration efanele kubalulekile. Ukufaka izithako ezishisa amafutha ohlelweni lwakho lwansuku zonke kungahambisana nalezi zinguquko zendlela yokuphila futhi kukusize ufinyelele imigomo yakho yokulahlekelwa isisindo.
Izithako ezishisa amafutha ziyimikhiqizo yokudla eyenzelwe ukuthuthukisa i-fat metabolism noma izindleko zamandla, okuholela ekwehleni kwesisindo. Afika ngezindlela eziningi, okuhlanganisa amaphilisi, amaphilisi, nezimpushana, futhi ngokuvamile aqukethe izithako zemvelo ezifana namakhambi, amaminerali, namavithamini. Lezi zithako zenzelwe ukukhulisa imetabolism, ukucindezela ukudla, noma ukuvimba ukumuncwa kwamafutha emzimbeni.
Enye indlela izithasiselo ezishisa amafutha ezingakusiza ukuthi ulahlekelwe isisindo ngokwandisa izinga lakho lokugayeka kokudla. Izinga le-metabolic lisho ukuthi umzimba wakho uguqula ngokushesha kanjani ukudla kube amandla. Uma i-metabolism yakho iphakeme, umzimba wakho ushisa ama-calories ngokuphumelelayo, ngisho nalapho uphumule. Izithako ezithile ezithasiselweni ezishisa amafutha, njenge-caffeine noma itiye elihlaza, zingakhuphula izinga lokugaya, ngaleyo ndlela zandise ukushiswa kwekhalori.
Enye indlela yokusebenzisa izithako zokushiswa kwamafutha kusiza ekunciphiseni isisindo ngokucindezela isifiso sokudla. Ezinye izithasiselo ziqukethe izithako ezifana nefayibha noma amaprotheni angakha umuzwa wokusutha, okukuvumela ukuthi udle kancane futhi unciphise ukudliwa kwekhalori. Ngokunciphisa isifiso sokudla ngokweqile, lezi zithako zingase zisekele uhambo lwakho lokulahlekelwa isisindo futhi zivimbele ukudla okungenasidingo noma ukuzitika ngokudla okungenampilo.
Ngaphezu kokwandisa i-metabolism nokucindezela isifiso sokudla, izithako ezishisa amafutha zingase futhi zivimbele ukumuncwa kwamafutha emzimbeni.
Kodwa-ke, kubalulekile ukuqaphela ukuthi kufanele zisetshenziswe ngokuhambisana nokudla okunempilo nokuzivocavoca okuvamile. Lezi zithako zenzelwe ukusekela imizamo yakho yokulahlekelwa isisindo, kodwa azihloselwe ukuthatha indawo yecebo lokudla okunomsoco noma umsebenzi womzimba. Kubalulekile ukuthatha indlela eqhubekayo nephelele yokwehlisa isisindo, okuhlanganisa ukudla okulawulwa ngamakhalori, ukuzivocavoca okuvamile, nokulala okufanele.
Okokuqala, ake siqonde ukuthi yini6-Paradol kuyinto. I-6-Paradol, etholakala embewini yesitshalo se-African cardamom (esivame ukwaziwa ngokuthi upelepele waseGuinea), iyinhlanganisela eyenzeka ngokwemvelo eyi-ketone enamakha avuselelayo. Iwumthombo wokunambitheka okubabayo kukapelepele futhi ngokwesiko ibisetshenziselwa izinjongo zokwelapha ezahlukahlukene.
Enye yezindlela eziyinhloko i-6-Paradol esiza ngokunciphisa isisindo ngokuvuselela i-thermogenesis. I-Thermogenesis inqubo lapho imizimba yethu ikhiqiza ukushisa ngokushisa ama-calories. Ngokwandisa i-thermogenesis, i-6-Paradol inyusa izinga imizimba yethu eshisa ngayo amafutha. Lokhu kubangela i-metabolism ephezulu futhi ekugcineni kwehle isisindo. Ucwaningo oluningi luye lwabonisa ukuthi i-6-Paradol ingakhuphula kakhulu i-thermogenesis, ikwenze kube inketho ekhangayo kulabo abafuna ukulahlekelwa amafutha amaningi.
Esinye isici esinomthelela ekushiseni amafutha kwe-6-Paradol yikhono layo lokwenza izicubu ze-adipose ezinsundu (BAT) zisebenze. Ngokungafani nezicubu ezimhlophe ze-adipose (WAT), ezigcina amandla engeziwe njengamafutha, i-BAT inesibopho sokushisa ama-calories ukukhiqiza ukushisa. Ngakho-ke, ukusebenzisa i-BAT kusiza ukulahlekelwa isisindo njengoba kusiza ukushisa amafutha agciniwe. Ucwaningo lwakamuva lubonise ukuthi i-6-Paradol ingavula i-BAT futhi ikhulise umsebenzi wayo. Lokhu kutholwa kuvula amathuba amasha okusebenzisa i-6-Paradol njengethuluzi lokunciphisa isisindo.
Ngaphezu kwemiphumela yayo ku-thermogenesis kanye nokusebenza kwe-BAT, i-6-Paradol yatholakala ukuthi ivimbela ukuhlukaniswa kwama-preadipocyte abe ama-adipocyte avuthiwe. Ama-preadipocyte amangqamuzana angaphambili angathuthuka abe amaseli amafutha avuthiwe, okuholela ekwandeni kwenani lamaseli amafutha. Ngokuvimbela le nqubo, i-6-Paradol ikhawulela ukuqoqwa kwamaseli amafutha emizimbeni yethu. Lokhu kunenzuzo ikakhulukazi kubantu abanenkinga yokukhuluphala ngokweqile noma izinkinga zokulawula isisindo.
Ukwengeza, i-6-Paradol ibonisa isithembiso ekuthuthukiseni ukusebenza kwezemidlalo nokululama, izici ezibalulekile kunoma iyiphi inqubo yokulahlekelwa isisindo. Ucwaningo olulodwa ezilwaneni lwathola ukuthi ukugcwalisa nge-6-Paradol kwandisa ukukhuthazela nokunciphisa ukulimala kwemisipha. Ngokuthuthukisa ukusebenza kwezemidlalo, abantu bangajima kakhulu, bashise amakholori engeziwe, futhi balahlekelwe amafutha ngokuphumelelayo.
Okokuqala, kubalulekile ukugcizelela ukubaluleka kokuthintana nochwepheshe bezempilo ngaphambi kokufaka noma yisiphi isithasiselo ohlelweni lwakho lwansuku zonke. Uchwepheshe wezokwelapha uzohlola impilo yakho iyonke, noma yiziphi izimo zezokwelapha ezicashile, kanye nemithi ongase uyiphuze engase ihlanganyele nesithasiselo.
Isinyathelo esilandelayo siwukucwaninga kahle isithunzi nokwethembeka komkhiqizo noma umkhiqizi. Bheka izinkampani namabhizinisi anomlando oqinisekisiwe wokukhiqiza izithako eziphephile nezithembekile. Kunconywa ukuthi ukhethe imikhiqizo osekunesikhathi ikhona emakethe njengoba lokhu kukhombisa ukuthi isihloliwe futhi yazuza ukwethenjwa ngabathengi.
Ukufunda amalebula omkhiqizo kuyisici esibalulekile sokuthola isengezo esiphephile nesithembekile sokushiswa kwamafutha. Bheka obala ohlwini lwezithako, lapho zonke izithako zicaciswe ngokucacile. Gwema imikhiqizo enezingxube zobunikazi ezifihla amanani athile esithako ngasinye, okwenza kube nzima ukuhlola ukusebenza kwawo nokuphepha.
Ukuhlola kanye nesitifiketi somuntu wesithathu kunikeza isiqinisekiso esengeziwe lapho ukhetha isithasiselo esishisa amafutha. Hlola ukuthi imikhiqizo ihlolwa ngamalabhorethri azimele ukuze kutholakale ubumsulwa, ikhwalithi kanye namazinga okuphepha. Izitifiketi ezifana ne-NSF International, United States Pharmacopeia (USP), noma i-Natural Products Association (NPA) zibonisa ukuthi umkhiqizo uhlangabezana nezindinganiso eziqinile. Lezi zitifiketi zisebenza njengezinkomba zokwethembeka nokuvikeleka.
Ukubuyekezwa kwabathengi kanye nempendulo kungaba yinsiza ebalulekile yokulinganisa ukusebenza nokuphepha kwezithasiselo ezishisa amafutha. Nokho, ukuqapha kufanele kusetshenziswe lapho kuncika kuphela kulezi zibuyekezo. Bheka izibuyekezo ezivela emithonjeni ethembekile noma kubathengi abaqinisekisiwe. Naka izingqikithi eziphindaphindayo, ezinhle nezingezinhle, ukuze uthole ukuqonda okuphelele kwezinzuzo ezingaba khona zesithasiselo kanye nemiphumela engemihle engaba khona.
I-Suzhou Myland Pharm & Nutrition Inc. ibambe iqhaza ebhizinisini lesengezo sokudla okunempilo kusukela ngo-1992. Yinkampani yokuqala eShayina ukuthuthukisa nokudayisa imbewu yamagilebhisi.
Njengoba sinesipiliyoni seminyaka engu-30 futhi siqhutshwa ubuchwepheshe obuphezulu kanye namasu e-R&D athuthukiswe kakhulu, sithuthukise uhide lwemikhiqizo encintisanayo futhi saba isithasiselo sesayensi yempilo esitsha, ukuhlanganisa ngokwezifiso kanye nenkampani yezinkonzo zokukhiqiza. Ngaphezu kwalokho, inkampani iphinde ibe ngumkhiqizi obhalisiwe we-FDA, oqinisekisa impilo yabantu ngekhwalithi ezinzile nokukhula okuqhubekayo. Ikhiqiza futhi ithole izinhlobonhlobo zezithako zokudla okunomsoco, imithi, futhi iyaziqhenya ngokunikela ngemikhiqizo okungekho enye inkampani engayinikeza.
Izinsiza ze-R&D zenkampani kanye nezindawo zokukhiqiza kanye namathuluzi okuhlaziya kungokwesimanje futhi ahlukahlukene, futhi ayakwazi ukukhiqiza amakhemikhali esikalini se-milligram kuya kuthani, ngokuhambisana namazinga e-ISO 9001 kanye nezinqubo zokukhiqiza ze-GMP.
Ukwengeza, kubalulekile ukukhumbula ukuthi izithako ezishisa amafutha kufanele zihlale zihambisana nokudla okunempilo nokuzivocavoca okuvamile. Qaphela imikhiqizo ethembisa imiphumela esheshayo noma eqinisekisa ukwehla kwesisindo ngaphandle kokwenza izinguquko endleleni yokuphila. Izimangalo ezinjalo zivame ukuba zinhle kakhulu ukuba zibe yiqiniso futhi zingase zibonise ukuntuleka kokuphepha nokuthembeka komkhiqizo.
Okokugcina, zijwayeze ngemiphumela emibi engase ibe khona futhi uqonde imithamo enconyiwe. Landela imiyalelo enikezwe umenzi futhi ungalokothi weqe umthamo onconywayo, ucabanga ukuthi lokhu kuzothuthukisa ukwehla kwesisindo.
1. Thuthukisa ukukhiqizwa kwamandla kwamaselula
I-NR idlala indima ebalulekile ekukhiqizweni kwe-molecule ebalulekile i-nicotinamide adenine dinucleotide (NAD+). I-NAD+ ibandakanyeka ezinqubweni ezihlukene zamaselula, okuhlanganisa i-energy metabolism. Njengoba sikhula, amazinga e-NAD+ emizimbeni yethu ayancipha, okuholela ekunciphiseni kokukhiqizwa kwamandla. Ngokuphromotha ukuhlanganiswa kwe-NAD+, i-NR isiza ukuvuselela amaseli futhi inike amandla ukukhiqizwa kwamandla okusebenzayo. La mandla eselula athuthukisiwe anyusa amandla, athuthukisa ukusebenza komzimba, futhi anciphise nokukhathala.
2. Ukuvimbela ukuguga kanye nokulungiswa kwe-DNA
Ukwehla kwamazinga e-NAD+ kuhlotshaniswa nokuguga kanye nezifo ezihlobene nobudala. I-NR ingakhuphula amazinga e-NAD+ emzimbeni, iyenze ibe i-ejenti elwa nokuguga. I-NAD+ ibandakanyeka ezindleleni zokulungisa i-DNA, iqinisekisa ubuqotho bempahla yethu yofuzo. Ngokuphromotha ukulungiswa kwe-DNA, i-NR ingasiza ekuvimbeleni ukulimala kwe-DNA ehlobene neminyaka futhi isekele ukuguga okunempilo. Ukwengeza, indima ye-NR ekwenzeni kusebenze ama-sirtuin, ikilasi lamaprotheni elaziwa ngokulawula impilo yamangqamuzana nokuphila isikhathi eside, lithuthukisa futhi amandla awo okulwa nokuguga.
3. Impilo yenhliziyo nemithambo yegazi
Ukugcina uhlelo lwenhliziyo olunempilo kubalulekile empilweni yonke. INicotinamide riboside ikhombise imiphumela ethembisayo empilweni yenhliziyo nemithambo yegazi. Isekela umsebenzi wamangqamuzana e-vascular endothelial, ikhuthaza ukugeleza kwegazi futhi inciphise ukuvuvukala. I-NR iphinde ithuthukise umsebenzi we-mitochondrial kumaseli enhliziyo, ivimbele ukucindezelwa kwe-oxidative nokwandisa ukukhiqizwa kwamandla. Le miphumela ingasiza ekunciphiseni ubungozi bezifo zenhliziyo nemithambo yegazi njenge-atherosclerosis nesifo senhliziyo.
4. I-Neuroprotection kanye nokusebenza kwengqondo
I-NR ikhonjiswe ukuthi inezakhiwo ze-neuroprotective, okuyenza ibe umngane ongaba khona ekugcineni impilo yobuchopho. Kungaba nomthelela omuhle ekusebenzeni kwe-neuronal futhi kuvikele ekunciphiseni kwengqondo okuhlobene neminyaka. Ngokwandisa amazinga e-NAD+, i-NR isekela ukusebenza kwe-mitochondrial kumangqamuzana obuchopho, ithuthukisa ukukhiqizwa kwamandla futhi ikhuthaze ukulungiswa kwamaselula. Ukuthuthukisa umsebenzi we-mitochondrial kungathuthukisa amakhono okuqonda njengenkumbulo, ukugxilisa ingqondo, kanye nokucaca kwengqondo okuphelele.
5. Ukulawulwa Kwesisindo kanye Nempilo Ye-Metabolic
Ukugcina isisindo esinempilo kanye nebhalansi ye-metabolic kubalulekile empilweni yethu yonke. I-NR ixhunyaniswe nemiphumela enenzuzo kumetabolism, okwenza kube usizo olungaba khona ekulawuleni isisindo. I-NR yenza kusebenze iphrotheni ebizwa nge-Sirtuin 1 (SIRT1), elawula izinqubo ze-metabolic ezifana ne-glucose metabolism kanye nokugcinwa kwamafutha. Ngokuvula i-SIRT1, i-NR ingasiza ekunciphiseni isisindo futhi ithuthukise impilo ye-metabolic, ngaleyo ndlela yehlise ubungozi bezifo ezinjengokukhuluphala kanye nesifo sikashukela sohlobo 2.
Q: Yiziphi izithako ezishisa amafutha?
IMP: Izithako ezishisa amafutha ziyizithako zokudla eziqukethe izithako ezithile ezihloselwe ukuthuthukisa i-metabolism, ukukhulisa i-oxidation yamafutha, noma ukucindezela ukudla, ekugcineni zisize ekunciphiseni isisindo kanye nokushiswa kwamafutha.
Q: Zisebenza kanjani izithako ezishisa amafutha?
A: Lezi zithako zisebenza ngezindlela ezahlukahlukene. Ezinye zithuthukisa i-thermogenesis, okwandisa izinga lokushisa lomzimba, okuholela ekushiseni kwe-metabolism kanye nokushiswa kwekhalori. Ezinye zisiza ukucindezela ukudla, ukunciphisa ukumuncwa kwamafutha, noma ukukhuthaza ukuwohloka kwamangqamuzana amafutha agciniwe.
Umshwana wokuzihlangula: Lesi sihloko esolwazi oluvamile kuphela futhi akufanele sithathwe njengeseluleko sezokwelapha. Olunye ulwazi lokuthunyelwe kwebhulogi luvela ku-inthanethi futhi alusebenzi. Le webhusayithi inomthwalo wemfanelo kuphela wokuhlunga, ukufometha kanye nokuhlela ama-athikili. Injongo yokudlulisa ulwazi olwengeziwe ayisho ukuthi uyavumelana nemibono yayo noma uqinisekise ubuqiniso bokuqukethwe kwayo. Hlala uthintana nochwepheshe bezempilo ngaphambi kokusebenzisa noma yiziphi izithasiselo noma wenze izinguquko ohlelweni lwakho lokunakekelwa kwezempilo.
Isikhathi sokuthumela: Nov-15-2023
