Ezweni lanamuhla elisheshayo, ukugcina indlela yokuphila enempilo kuya ngokuya kuba yinto ebaluleke kakhulu. Esinye sezihluthulelo zokuphila okunempilo ukulawula isisindo. Ukuqongelela amafutha ngokweqile akugcini nje ngokuthinta ukubukeka kwethu kodwa futhi kusibeka engcupheni yezinkinga ezahlukene zempilo. Nakuba ukudla okungapheli kanye nokuzivocavoca okunzima kunganikeza imiphumela esheshayo, kuvame ukwehluleka ukunikeza ikhambi eliqhubekayo. Izithako zokushisa amafutha zingasisiza ukuba sinciphise isisindo esiningi futhi sifinyelele umzimba onempilo nowomzimba omncane.
Uma kukhulunywa ngokunciphisa isisindo, abantu abaningi basebenzisa izindlela ezahlukahlukene, kusukela ekudleni okuphansi kuya ekuzivocavoceni. Kodwa-ke, isu elilodwa eliphumelelayo elivame ukunganakwa ukufaka izithako ezishisa amafutha ekudleni kwethu kwansuku zonke. Lezi zithako zingasiza ekusheshiseni imetabolism yethu futhi zikhuthaze ukwehla kwesisindo.
Izithako ezishisa amafutha yizinto ezitholakale zikhuthaza ukuqhekeka nokusetshenziswa kwamafutha agciniwe emzimbeni. Zitholakala ekudleni okuthile, emakhambi nasezinongoni futhi zaziwa ngekhono lazo lokukhulisa imetabolism, ukucindezela isifiso sokudla kanye nokuthuthukisa ukushiswa kwamafutha. Ngokungafani nalezi zithako ezishisa amafutha, izithako ezishisa amafutha ngokuvamile ziyizithako ezenzelwe ngqo ukusheshisa inqubo yokulahlekelwa amafutha futhi zenziwe ngezithako zemvelo ezisiza ekukhuliseni imetabolism, ukucindezela isifiso sokudla, kanye nokwandisa amazinga amandla. Lezi zithako zenzelwe ukuthuthukisa ikhono lomzimba lokushisa amafutha ngokubhekisa izindlela ezahlukene ngaphakathi kohlelo lwethu.
Esinye isithako esidumile sokushisa amafutha yi-green tea extract. Itiye eliluhlaza liqukethe ama-catechin, i-antioxidant eye yabonakala isiza ekwandiseni i-metabolism futhi ikhuthaze ukulahleka kwamafutha. Izifundo zithole ukuthi ukudla i-green tea extract kungandisa ukusetshenziswa kwama-calories kanye ne-oxidation yamafutha, okwenza kube yinto ewusizo kunoma yiluphi uhlelo lokunciphisa isisindo.
Esinye isithako esinamandla sokushisa amafutha yi-capsaicin, evame ukutholakala kupelepele opelepele. I-Capsaicin inezakhiwo ze-thermogenic, okusho ukuthi inyusa izinga lokushisa lomzimba futhi ikhuphule imetabolism. Kutholakale nokuthi icindezela isifiso sokudla futhi yehlise ukudla okunama-calories. Ukwengeza upelepele we-cayenne ekudleni kwakho noma ukuthatha isithasiselo se-capsaicin kungasiza ekuqaliseni uhambo lwakho lokushisa amafutha.
Ngaphezu kwalezi zithako, kutholakale ukuthi amakhambi athile nezinongo zinezakhiwo zokushisa amafutha. Isibonelo, isinamoni iboniswe ukuthi isiza ukulawula amazinga kashukela egazini, ngaleyo ndlela ivimbele ukugcinwa kwamafutha ngokweqile. Ngakolunye uhlangothi, i-turmeric iqukethe i-curcumin, into etholakala isiza ekunciphiseni isisindo ngokunciphisa ukuvuvukala nokuthuthukisa ukuzwela kwe-insulin.
Kubalulekile ukuqaphela ukuthi nakuba izithako ezishisa amafutha zingasiza ekunciphiseni isisindo, aziyona ikhambi eliphelele. Ukuze ufinyelele ekunciphiseni isisindo okuhlala isikhathi eside, ukudla okunempilo okunempilo, ukuzivocavoca njalo kanye nokuphuza amanzi anele kubalulekile. Ukufaka izithako ezishisa amafutha ohlelweni lwakho lwansuku zonke kungaphelelisa lezi zinguquko zendlela yokuphila futhi kukusize ufinyelele imigomo yakho yokunciphisa isisindo.
Izithako zokushisa amafutha yimikhiqizo yokudla eyenzelwe ukuthuthukisa i-metabolism yamafutha noma ukusetshenziswa kwamandla, okuholela ekunciphiseni isisindo. Ziza ngezindlela eziningi, kufaka phakathi amaphilisi, ama-capsule, kanye nophudingi, futhi zivame ukuqukethe izithako zemvelo ezifana namakhambi, amaminerali, namavithamini. Lezi zithako zenzelwe ukwandisa i-metabolism, ukucindezela isifiso sokudla, noma ukuvimba ukumuncwa kwamafutha emzimbeni.
Enye indlela izithasiselo zokushisa amafutha ezingakusiza ngayo ukwehlisa isisindo ukwandisa izinga lakho lokuguqulwa kwezakhi zomzimba. Izinga lokuguqulwa kwezakhi zomzimba libhekisela ekutheni umzimba wakho uguqula ngokushesha kangakanani ukudla kube amandla. Uma i-metabolism yakho iphezulu, umzimba wakho ushisa amakhalori ngempumelelo enkulu, ngisho nalapho uphumule. Izithako ezithile ezitholakala kwizithasiselo zokushisa amafutha, njenge-caffeine noma i-green tea extract, zingakhuphula izinga lokuguqulwa kwezakhi zomzimba, ngaleyo ndlela zandise ukushiswa kwamakhalori.
Enye indlela izithasiselo ezishisa amafutha ezisiza ngayo ukwehlisa isisindo ukucindezela isifiso sokudla. Ezinye izithasiselo ziqukethe izithako ezifana ne-fiber noma iphrotheni ezingadala umuzwa wokugcwala, okukuvumela ukuthi udle kancane futhi unciphise ukudla okunama-calories amaningi. Ngokunciphisa isifiso sokudla ngokweqile, lezi zithasiselo zingasekela uhambo lwakho lokunciphisa isisindo futhi zivimbele ukudla okulula okungadingekile noma ukuzitika ngokudla okungenampilo.
Ngaphezu kokwandisa imetabolism nokucindezela isifiso sokudla, izithasiselo ezishisa amafutha zingase zivimbele ukumuncwa kwamafutha emzimbeni.
Kodwa-ke, kubalulekile ukuqaphela ukuthi kufanele zisetshenziswe kanye nokudla okunempilo kanye nokuzivocavoca njalo. Lezi zithako zenzelwe ukusekela imizamo yakho yokwehlisa isisindo, kodwa azihloselwe ukuthatha indawo yohlelo lokudla olulinganiselayo noma umsebenzi womzimba. Kubalulekile ukuthatha indlela eqhubekayo nephelele yokwehlisa isisindo, okuhlanganisa ukudla okulawulwa amakhalori, ukuzivocavoca njalo, kanye nokulala kahle.
Okokuqala, ake siqonde ukuthi yini6-I-Paradol I-6-Paradol, etholakala embewini yesitshalo se-African cardamom (esaziwa kakhulu ngokuthi i-Guinea pepper), iyinhlanganisela yemvelo eyi-ketone enuka kamnandi evuselelayo. Iwumthombo wokunambitheka okubabayo kwepelepele futhi ibilokhu isetshenziswa ngokwesiko ngezinjongo ezahlukahlukene zokwelapha.
Enye yezindlela eziyinhloko i-6-Paradol esiza ngazo ekunciphiseni isisindo iwukukhuthaza i-thermogenesis. I-Thermogenesis inqubo lapho imizimba yethu ikhiqiza khona ukushisa ngokushisa amakhalori. Ngokwandisa i-thermogenesis, i-6-Paradol yandisa izinga lapho imizimba yethu ishisa khona amafutha. Lokhu kuphumela ekusetshenzisweni kwe-metabolism okuphezulu futhi ekugcineni kwehle isisindo. Izifundo eziningi zikhombisile ukuthi i-6-Paradol ingakhulisa kakhulu i-thermogenesis, okwenza kube inketho ekhangayo kulabo abafuna ukunciphisa amafutha amaningi.
Esinye isici esibangela izakhiwo zokushisa amafutha ze-6-Paradol yikhono layo lokuvuselela izicubu zamafutha ansundu (BAT). Ngokungafani nezicubu zamafutha ezimhlophe (WAT), ezigcina amandla amaningi njengamafutha, i-BAT inesibopho sokushisa amakhalori ukuze ikhiqize ukushisa. Ngakho-ke, ukwenza i-BAT isebenze kusiza ekunciphiseni isisindo njengoba isiza ekushiseni amafutha agciniwe. Izifundo zakamuva zikhombisile ukuthi i-6-Paradol ingavuselela i-BAT futhi yandise umsebenzi wayo. Lokhu kutholwa kuvula amathuba amasha okusebenzisa i-6-Paradol njengethuluzi lokunciphisa isisindo.
Ngaphezu kwemiphumela yayo ekukhuleni kwe-thermogenesis kanye nokusebenza kwe-BAT, i-6-Paradol itholakale ivimbela ukuhlukaniswa kwama-preadipocytes abe ama-adipocytes avuthiwe. Ama-Preadipocytes angamaseli angaphambi kwesikhathi angakhula abe amaseli amafutha avuthiwe, okuholela ekwandeni kwenani lamaseli amafutha. Ngokuvimbela le nqubo, i-6-Paradol ikhawulela ukuqongelela kwamaseli amafutha emizimbeni yethu. Lokhu kuzuzisa kakhulu abantu ababhekene nezinkinga zokukhuluphala noma zokulawula isisindo.
Ngaphezu kwalokho, i-6-Paradol ikhombisa ithemba ekuthuthukiseni ukusebenza kwezemidlalo kanye nokululama, okuyizinto ezibalulekile kunoma iyiphi inqubo yokwehlisa isisindo. Ucwaningo olulodwa olwenziwe ezilwaneni luthole ukuthi ukwengeza i-6-Paradol kwandisa ukukhuthazela futhi kunciphisa ukulimala kwemisipha. Ngokuthuthukisa ukusebenza kwezemidlalo, abantu bangavocavoca kakhulu, bashise amakhalori amaningi, futhi balahlekelwe amafutha ngempumelelo enkulu.
Okokuqala, kubalulekile ukugcizelela ukubaluleka kokubonisana nochwepheshe wezempilo ngaphambi kokufaka noma yisiphi isithasiselo ohlelweni lwakho lwansuku zonke. Uchwepheshe wezokwelapha uzohlola impilo yakho iyonke, noma yiziphi izimo zezokwelapha eziyisisekelo, kanye nemithi ongase uyithathe engase ihlangane nesithasiselo.
Isinyathelo esilandelayo ukucwaninga ngokucophelela idumela kanye nokwethembeka komkhiqizo noma umenzi. Funa izinkampani namabhizinisi anomlando oqinisekisiwe wokukhiqiza izithasiselo eziphephile nezithembekile. Kunconywa ukukhetha imikhiqizo ebilokhu isemakethe isikhathi eside njengoba lokhu kukhombisa ukuthi ihlolwe futhi izuze ukwethenjwa ngabathengi.
Ukufunda amalebula emikhiqizo kuyisici esibalulekile sokuthola isithasiselo esiphephile nesithembekile sokushisa amafutha. Funa ukucaca ohlwini lwezithako, lapho zonke izithako zichazwe khona ngokucacile. Gwema imikhiqizo enezingxube ezizimele ezifihla inani elithile lesithako ngasinye, okwenza kube nzima ukuhlola ukusebenza kwayo kanye nokuphepha kwayo.
Ukuhlolwa kanye nesitifiketi seqembu lesithathu kunikeza isiqinisekiso esengeziwe lapho ukhetha isithasiselo esishisa amafutha. Hlola ukuthi imikhiqizo ihlolwa amalabhorethri azimele ukuze kutholakale ubumsulwa, ikhwalithi kanye nezindinganiso zokuphepha. Izitifiketi ezifana ne-NSF International, i-United States Pharmacopeia (USP), noma i-Natural Products Association (NPA) zibonisa ukuthi umkhiqizo uhlangabezana nezindinganiso eziqinile. Lezi zitifiketi zisebenza njengezinkomba zokuthembeka nokuphepha.
Ukubuyekezwa kwabathengi kanye nempendulo kungaba umthombo obalulekile wokulinganisa ukusebenza kahle kanye nokuphepha kwezithako ezishisa amafutha. Kodwa-ke, kufanele kuqashelwe uma uthembele kuphela kulezi zibuyekezo. Funa ukubuyekezwa okuvela emithonjeni ethembekile noma kubathengi abaqinisekisiwe. Naka izihloko eziphindaphindayo, ezinhle nezimbi, ukuze uthole ukuqonda okuphelele ngezinzuzo ezingaba khona zesithako kanye nemiphumela emibi engaba khona.
I-Suzhou Myland Pharm & Nutrition Inc. ibilokhu ibandakanyeka ebhizinisini lezithako zokudla okunempilo kusukela ngo-1992. Yinkampani yokuqala eShayina ukuthuthukisa nokuthengisa okukhishwe kwembewu yamagilebhisi.
Njengoba sineminyaka engama-30 yesipiliyoni futhi siqhutshwa ubuchwepheshe obuphezulu kanye namasu e-R&D athuthukisiwe kakhulu, sithuthukise imikhiqizo ehlukahlukene yokuncintisana futhi saba yinkampani yezinsizakalo zesayensi yokuphila entsha, ukuhlanganiswa ngokwezifiso kanye nokukhiqiza. Ngaphezu kwalokho, inkampani futhi ingumkhiqizi obhalisiwe yi-FDA, eqinisekisa impilo yabantu ngekhwalithi ezinzile kanye nokukhula okusimeme. Ikhiqiza futhi ithola uhla olubanzi lwezithako zokudla okunempilo, imithi, futhi iyaziqhenya ngokunikeza imikhiqizo engekho enye inkampani engayinikeza.
Izinsiza ze-R&D zenkampani kanye nezindawo zokukhiqiza kanye nezinsimbi zokuhlaziya zisesimanje futhi ziyasebenziseka, futhi ziyakwazi ukukhiqiza amakhemikhali esikalini sama-milligram kuya kuma-ton, ngokuhambisana nezindinganiso ze-ISO 9001 kanye nemikhuba yokukhiqiza ye-GMP.
Ngaphezu kwalokho, kubalulekile ukukhumbula ukuthi izithako zokushisa amafutha kufanele zihambisane nokudla okunempilo kanye nokuzivocavoca njalo. Qaphela imikhiqizo ethembisa imiphumela esheshayo noma eqinisekisa ukwehla kwesisindo ngaphandle kokwenza izinguquko endleleni yokuphila. Izimangalo ezinjalo zivame ukuba zinhle kakhulu ukuba zingaba yiqiniso futhi zingase zibonise ukuntuleka kokuphepha nokuthembeka komkhiqizo.
Okokugcina, zijwayeze nemiphumela emibi engaba khona futhi uqonde imithamo enconyiwe. Landela imiyalelo enikezwe umenzi futhi ungalokothi weqe umthamo onconyiwe, ucabanga ukuthi lokhu kuzosheshisa kakhulu ukwehla kwesisindo.
1. Thuthukisa ukukhiqizwa kwamandla eselula
I-NR idlala indima ebalulekile ekukhiqizweni kwe-molecule ebalulekile i-nicotinamide adenine dinucleotide (NAD+). I-NAD+ ihilelekile ezinqubweni ezahlukahlukene zamaseli, okuhlanganisa nokusetshenziswa kwamandla. Njengoba siguga, amazinga e-NAD+ emizimbeni yethu ayancipha, okuholela ekukhiqizweni kwamandla okuncishisiwe. Ngokukhuthaza ukwenziwa kwe-NAD+, i-NR isiza ukuvuselela amaseli futhi ivumele ukukhiqizwa kwamandla okuphumelelayo. Lawa mandla eselula athuthukisiwe andisa amandla, athuthukisa ukusebenza ngokomzimba, futhi anciphise ukukhathala.
2. Ukulungiswa kwe-DNA nokulwa nokuguga
Ukwehla kwamazinga e-NAD+ kuhlotshaniswa nokuguga kanye nezifo ezihlobene nokuguga. I-NR ingakhuphula amazinga e-NAD+ emzimbeni, okwenza kube yinto engaba khona yokulwa nokuguga. I-NAD+ ihilelekile ezindleleni zokulungisa i-DNA, iqinisekisa ubuqotho bezinto zethu zofuzo. Ngokukhuthaza ukulungiswa kwe-DNA, i-NR ingasiza ekuvimbeleni ukulimala kwe-DNA okuhlobene nokuguga futhi isekele ukuguga okunempilo. Ngaphezu kwalokho, indima ye-NR ekusebenziseni ama-sirtuin, uhlobo lwamaprotheni aziwa ngokulawula impilo yamaseli kanye nokuphila kwawo, ithuthukisa kakhulu amandla ayo okulwa nokuguga.
3. Impilo yenhliziyo nemithambo yegazi
Ukugcina uhlelo lwenhliziyo olunempilo kubalulekile empilweni iyonke. I-Nicotinamide riboside ibonise imiphumela ethembisayo empilweni yenhliziyo. Isekela umsebenzi wamaseli endothelial emithambo yegazi, ikhuthaza ukugeleza kwegazi futhi inciphise ukuvuvukala. I-NR iphinde ithuthukise umsebenzi we-mitochondrial emaseli enhliziyo, ivimbele ukucindezeleka kwe-oxidative futhi ithuthukise ukukhiqizwa kwamandla. Le miphumela ingasiza ekunciphiseni ingozi yezifo zenhliziyo ezifana ne-atherosclerosis kanye nokwehluleka kwenhliziyo.
4. Ukuvikela izinzwa kanye nokusebenza kwengqondo
I-NR iboniswe inezakhiwo zokuvikela izinzwa, okwenza ibe umsizi ongaba khona ekugcineni impilo yobuchopho. Ingaba nomthelela omuhle ekusebenzeni kwezinzwa futhi ivikele ekuwohlokeni kokuqonda okuhlobene nobudala. Ngokwandisa amazinga e-NAD+, i-NR isekela ukusebenza kwe-mitochondrial emaseli obuchopho, ithuthukisa ukukhiqizwa kwamandla futhi ikhuthaza ukulungiswa kwamaseli. Ukuthuthukisa ukusebenza kwe-mitochondrial kungathuthukisa amakhono okuqonda njengenkumbulo, ukugxilisa ingqondo, kanye nokucaca kwengqondo iyonke.
5. Ukuphathwa Kwesisindo kanye Nempilo Yomzimba
Ukugcina isisindo esinempilo kanye nebhalansi ye-metabolic kubalulekile empilweni yethu iyonke. I-NR ixhunyaniswe nemiphumela emihle ekusetshenzisweni kwe-metabolism, okwenza kube usizo olukhulu ekulawuleni isisindo. I-NR isebenzisa iphrotheni ebizwa ngokuthi i-Sirtuin 1 (SIRT1), elawula izinqubo ze-metabolic ezifana nokusetshenziswa kwe-glucose kanye nokugcinwa kwamafutha. Ngokusebenzisa i-SIRT1, i-NR ingasiza ekunciphiseni isisindo futhi ithuthukise impilo ye-metabolic, ngaleyo ndlela inciphise ingozi yezifo ezifana nokukhuluphala ngokweqile kanye nesifo sikashukela sohlobo 2.
U: Ziyini izithako ezishisa amafutha?
A: Izithako zokudla ezishisa amafutha ziyizithako zokudla eziqukethe izithako ezithile ezihloselwe ukukhulisa i-metabolism, ukwandisa ukushiswa kwamafutha, noma ukucindezela isifiso sokudla, ekugcineni ezisiza ekunciphiseni isisindo nasekushiseni amafutha.
U: Izithako zokudla ezishisa amafutha zisebenza kanjani?
A: Lezi zithako zisebenza ngezindlela ezahlukene. Ezinye zithuthukisa i-thermogenesis, okwandisa izinga lokushisa lomzimba, okuholela ekusetshenzisweni kwe-metabolism okuphezulu kanye nokushiswa kwamakhalori. Ezinye zisiza ukucindezela isifiso sokudla, ukunciphisa ukumuncwa kwamafutha, noma ukukhuthaza ukuwohloka kwamaseli amafutha agciniwe.
Isixwayiso: Lesi sihloko senzelwe ulwazi olujwayelekile kuphela futhi akufanele sithathwe njenganoma yisiphi iseluleko sezokwelapha. Olunye ulwazi lweposi lebhulogi luvela kwi-inthanethi futhi alulona ochwepheshe. Le webhusayithi inesibopho sokuhlunga, ukufometha nokuhlela izihloko kuphela. Inhloso yokudlulisa ulwazi olwengeziwe akusho ukuthi uyavumelana nemibono yayo noma uqinisekisa ubuqiniso bokuqukethwe kwayo. Njalo xhumana nochwepheshe wezempilo ngaphambi kokusebenzisa noma yiziphi izithasiselo noma ukwenza izinguquko ohlelweni lwakho lokunakekelwa kwempilo.
Isikhathi sokuthunyelwe: Novemba-15-2023
