Kokubili abesilisa nabesifazane babhekana nokuqothuka kwezinwele futhi kungaba umthombo wokucindezeleka okukhulu futhi kungathinta kakhulu ukuzethemba komuntu nokuzethemba kwakhe.Ukuhlenga nokukhulula ukulahleka kwezinwele, kunezinketho eziningi zokwelashwa zokukhula kabusha kwezinwele emakethe kusukela ezindleleni zendabuko kuye emithini ethuthuke kakhulu.I-RU58841 eyethulwe esihlokweni esilandelayo isetshenziselwa ukukhula kwezinwele, ake sibheke ulwazi lwayo oluqondile!
Ngakho-ke, iyini ngempela i-RU58841?I-RU58841 iyinhlanganisela, eyaziwa nangokuthi i-PSK-3841, i-non-steroidal antiandrogen compound esetshenziselwa ngokuyinhloko ukwelapha.i-androgenetic alopecia(okuvame ukwaziwa ngokuthi impandla yephethini yowesilisa).Isebenza ngokuvimbela ama-androgen receptors esikhumbeni, okuholela ekunciphiseni kwezinwele zezinwele nokulahlekelwa izinwele okulandelayo.
I-RU58841 ilawula umjikelezo wokukhula kwezinwele ngokuncintisana ne-dihydrotestosterone ukuze kugcinwe amazinga e-DHT ngaphakathi kwebanga elivamile.Ukwengeza, i-RU58841 ikhuthaza ukuguqulwa kwezinwele ezintsha zezinwele zibe yizintambo zezinwele ze-anagen ngokungena esigabeni se-anagen.Ukuvumela ama-follicles alimele isikhathi sokushintshela esigabeni sokukhula esivamile kusiza amaseli ukuthi alulame.Ibuye ikhulise ukugeleza kwegazi ku-follicles eyonakele futhi ibasize ukuba bavuselele.
I-RU58841 iklanyelwe ukumisa noma ukunciphisa ukuqhubeka kokulahlekelwa izinwele ngokuvimbela isenzo se-androgens.Isebenza ngokubophezela kuma-androgen receptors kuma-follicle ezinwele.Ngakho-ke i-androgens ayinalo ithuba lokubopha futhi iqale ukusabela kweketango le-androgenetic alopecia futhi iqale inqubo ebizwa ngokuthi i-miniaturization.
1. Vimbela ukuqothuka kwezinwele
Enye yezinzuzo eziyinhloko zokusebenzisa i-RU58841 yikhono layo lokumisa ukulahlekelwa izinwele.Ngokuvimbela ngokukhetha ukubopha kwe-testosterone ne-dihydrotestosterone (DHT) ezinhlakeni zezinwele, kuvimbela inqubo ye-miniaturization yezinwele zezinwele, okuvumela izinwele zezinwele ukuba zigcine usayizi ojwayelekile nokusebenza.Lokhu kusho ukuthi i-RU58841 inamandla okunciphisa noma ngisho nokumisa ngokuphelele ukuqhubeka kokulahlekelwa izinwele.
2. Khuthaza ukukhula kabusha kwezinwele
Ucwaningo luye lwabonisa ukuthi i-RU58841 ingagqugquzela ukukhula kabusha kwezinwele ngaphezu kwamandla ayo okuvimbela ukulahlekelwa izinwele.Ngokuvimbela i-androgen receptors esikhumbeni, iphikisana nemiphumela yokungalingani kwama-hormone ezinhlakeni zezinwele, ezingabangela izinwele ezinciphile noma eziwayo ukuba zikhule kabusha.Nakuba ucwaningo olwengeziwe ludingeka ukuze kuqinisekiswe lesi simangalo, kunobufakazi bokuthi i-RU58841 inesithembiso njengokwelashwa okusebenzayo kokukhula kabusha kwezinwele.
3. Umthelela omncane wesistimu
Inzuzo enkulu ye-RU58841 uma iqhathaniswa neezinye izidakamizwa ze-antiandrogenukuthi inemiphumela emincane yesistimu.Njengoba kuyisixazululo se-topical, ihlose ikakhulukazi izintambo zezinwele nezicubu ezizungezile ngaphandle kokumuncwa ngohlelo.Lesi senzo sendawo sisiza ukugwema imiphumela emibi engadingeki engenzeka ngemithi yomlomo, ezuzisa labo abafisa ukubeka phambili ukukhula kwezinwele ngenkathi benciphisa ingozi yezinkinga zesistimu.
4. Ukuhambisana nezinye izindlela zokwelapha
Enye inzuzo engaba khona ye-RU58841 ukuhambisana kwayo nezinye izindlela zokwelapha zokulahlekelwa izinwele.Ingahlanganiswa nezidakamizwa ezidumile njenge-minoxidil ne-finasteride ukuze kube nomphumela we-synergistic.Ngokuhlanganisa i-RU58841 nalezi zindlela zokwelapha, iziguli zinamandla okuzuza ukukhula kwezinwele okuthuthukisiwe njengoba inhlanganisela ngayinye ihlose isici esihlukile sokulahlekelwa izinwele.
5. Ukusebenziseka kalula nokufinyeleleka
I-RU58841 iya ngokuya ifaneleka kulabo abafuna isisombululo sokulahlekelwa izinwele.Nakuba ekuqaleni yayihloselwe izinjongo zocwaningo kuphela, le nhlanganisela manje isiyatholakala kumakhemisi ahlanganisiwe ahlukahlukene kanye nabahlinzeki be-inthanethi abathembekile.Lokhu kufinyeleleka kuvumela abantu ukuthi bafake kalula le anti-androgen ethembisayo ohlelweni lwabo lokunakekelwa kwezinwele.
1. Sebenzisa
I-RU58841 iyi-antiandrogen engeyona i-steroidal eqondise ngokuqondile ama-androgen receptors esikhumbeni.Kucatshangwa ukuthi ivimbela imiphumela ye-dihydrotestosterone (DHT), i-hormone enkulu eyaziwa ngokubangela ukulahlekelwa izinwele.Ngokuvimbela i-DHT, i-RU58841 isiza ukuvimbela i-follicle atrophy yezinwele futhi yandise umjikelezo wokukhula kwezinwele.Lokhu ekugcineni kubangela izinwele ezijiyile, ezigcwele.I-RU58841 iyisixazululo se-topical esidinga ukufakwa ngqo esikhumbeni futhi asihloselwe ukusetshenziswa kwangaphakathi.
I-Minoxidil isidakamizwa esigunyazwe yi-FDA esisetshenziswe kabanzi ukwelapha ukulahleka kwezinwele amashumi eminyaka.Ekuqaleni yayisetshenziswa njengesidakamizwa esiphuzwayo ukwelapha umfutho wegazi ophakeme, kodwa umphumela wayo ohlangothini wokukhula kwezinwele waholela ekusetshenzisweni kwawo okuvamile njengesixazululo sesihloko sokulahlekelwa izinwele.Isebenza ngokunweba imithambo yegazi, ivumele umoya-mpilo owengeziwe, igazi, nezakhamzimba zifinyelele ezinhlamvini zezinwele.Lokhu kuthuthukisa ukukhula kwezinwele futhi kuthuthukisa ikhwalithi yonke yezinwele zakho.I-Minoxidil ifika iwuketshezi noma iyigwebu futhi isetshenziswa esikhunjeni sekhanda.Itholakala ekhawuntareni futhi yaziwa ukuthi iyasebenza kukho kokubili ukulahleka kwezinwele zephethini yowesilisa nowesifazane.
2. Ukusebenza kahle
Nakuba kokubili i-RU58841 kanye ne-minoxidil bathole ukunakwa ngamandla abo okukhuthaza ukukhula kabusha kwezinwele, umbono wabo wesayensi uyahluka.Kuye kwenziwa izifundo eziningi nge-minoxidil ukukhombisa ukuthi iyasebenza ekukhuthazeni ukukhula kabusha kwezinwele, ikakhulukazi ezigulini ezine-androgenetic alopecia.Ngokuphambene, izifundo zomtholampilo ezilinganiselwe zenziwe ku-RU58841, okwenza kube nzima ukuhlola ukusebenza kwayo kwangempela.Kodwa-ke, ubufakazi be-anecdotal nemibiko yomsebenzisi iphakamisa ukuthi i-RU58841 ingase imise ukulahlekelwa izinwele futhi ingase ibangele ukukhula kwezinwele, kodwa ucwaningo olwengeziwe luyadingeka ukuze kuqinisekiswe lezi zimangalo.
3. Izinzuzo kanye nemiphumela engemihle
Enye yezinzuzo ze-RU58841 ngaphezu kwe-minoxidil ukuntuleka okubikiwe kwemiphumela emibi yesistimu.Ngenxa yokuthi i-RU58841 isetshenziswa phezulu, kucatshangwa ukuthi ayinamathuba amancane okubangela ukusabela okubi kune-minoxidil, ngezinye izikhathi engabangela ukucasuka kwesikhumba, ukoma, ngisho nokwanda kwezinwele ezigabeni zokuqala zokwelashwa.Nokho, kubalulekile ukuqaphela ukuthi izimpendulo ngazinye zingahluka.
1. Izincomo zomthamo
Ibanga lethamo elinconyiwe le-RU58841 lingu-5 mg kuya ku-50 mg ngosuku, nabasebenzisi abaningi babika imiphumela emihle ngemithamo esukela ku-10 mg kuya ku-20 mg.Kunconywa ukuthi uqale ngomthamo ophansi futhi kancane kancane ukwandisa umthamo ukuze ulinganise ukubekezelelana nokuphendula komuntu ngamunye.Kubalulekile ukuthi ungadluli umthamo onconywayo njengoba lokhu kwandisa ingozi yemiphumela emibi ngaphandle kwenzuzo eyengeziwe.
Qaphela, i-RU58841 isetshenziswa ngokujwayelekile, hhayi ngomlomo.Lokhu kusho ukuthi i-compound ivame ukusetshenziswa ngqo esikhumbeni ngendlela yesisombululo noma i-foam.Njengesixazululo sesihloko, imithamo ivamise ukunikezwa ngamamililitha (ml) kunemilligrams (mg).Isiqalo esivamile sokusetshenziswa kwe-topical yi-1ml ngosuku, isetshenziswe ngokuqondile ezindaweni ezithintekile ze-scalp.
2. Imiphumela emibi nokuphepha
Nakuba i-RU58841 ibonise isithembiso njengokwelashwa kokuqothuka kwezinwele, kubalulekile ukuqonda imiphumela emibi engaba khona.Ngenxa yenani elilinganiselwe locwaningo olwenziwe kule nhlanganisela, ulwazi lwemiphumela emibi engaba khona lusavela.Nokho, abasebenzisi babike imiphumela engemihle embalwa, ikakhulukazi uma iqhathaniswa nokwelashwa kwendabuko njenge-finasteride noma i-minoxidil.
Yiqiniso, kungabaokuqhamuka uma udla imishanguzouma uyisebenzisa ngaphandle kokwazi umongo wakho.Nansi eminye yemiphumela yayo emibi kakhulu:
● abangenalo uhlu
●Yehlisa i-libido
●Kungase kube nokungezwani komzimba
●Ukucasuka kwesikhumba kanye nokuluma, ukoma, noma ukushwabuka
Kubalulekile ukuqaphela ukuthi akubona bonke abasebenzisi abahlangabezana nale miphumela engemihle, futhi ingahluka ngokuya ngezinto ezingazodwana.
Ukuqinisekisa izinga eliphezulu lokuphepha kanye nokunciphisa imiphumela engemihle, kubalulekile ukulandela umthamo onconywayo kanye neziqondiso zokusetshenziswa.Futhi, kunconywa kakhulu ukuthi ubonane nochwepheshe bezempilo ngaphambi kokuqala ukwelashwa kwe-RU58841, ikakhulukazi uma unomlando wezokwelapha ovele ukhona noma uthatha eminye imithi.
3. Ukusebenza kahle nemiphumela
Ukusebenza kwe-RU58841 ekulweni nokulahlekelwa izinwele kuyahlukahluka kumuntu nomuntu.Ngenkathi abanye abasebenzisi babika ukukhula kabusha kwezinwele nokujiya okuphawulekayo, abanye bangase bathole ukuthuthuka okuthobekile.Kubalulekile ukuphatha okulindelekile futhi uqonde ukuthi ukukhula kabusha kwezinwele kuyinqubo ehamba kancane edinga ukusetshenziswa okuqhubekayo esikhathini eside.Ukubekezela nokuphikelela kuyisihluthulelo uma usebenzisa i-RU58841.
Q: RU58841 Ingabe Iphephile Ukusetshenziswa Kwesikhathi Eside?
A: I-RU58841 iyisidakamizwa se-antiandrogenic esisetshenziswa kakhulu ekwelapheni ukulahleka kwezinwele.Nakuba ibonise imiphumela ethembisayo ekumiseni ukuqothuka kwezinwele nokukhuthaza ukukhula kwezinwele, ukuphepha kwayo kwesikhathi eside nokusebenza kwayo akukaqondwa ngokugcwele.
Kuyafaneleka ukusho ukuthi ukuzelapha noma ukusebenzisa noma yikuphi ukwelashwa kokulahlekelwa izinwele ngaphandle kokugadwa okufanele kwezokwelapha akukhuthazwa neze.Uchwepheshe wezokunakekelwa kwempilo angasiza ukuqapha ukuqhubeka kwakho, alungise umthamo uma kunesidingo, futhi aqinisekise ukuhlolwa okuvamile ukuze ahlole ukuphepha nokusebenza kokwelashwa.
Umshwana wokuzihlangula: Lesi sihloko senzelwe izinjongo zokwaziswa kuphela futhi akufanele sithathwe njengeseluleko sezokwelapha.Hlala uthintana nochwepheshe bezempilo ngaphambi kokusebenzisa noma yiziphi izithasiselo noma ukushintsha uhlobo lwakho lokunakekelwa kwezempilo.
Isikhathi sokuthumela: Jul-14-2023
