I-Spermidine, inhlanganisela yemvelo, ithole ukunakwa okukhulu ngenxa yekhono layo lokudala i-autophagy, engasiza amangqamuzana ukususa amaprotheni ayingozi kanye nemfucuza yamangqamuzana, ngaleyo ndlela ikhuthaze ukuvuselelwa kwamangqamuzana futhi ithuthukise impilo iyonke. Kulesi sihloko ku-Kumhlahlandlela wethu ophelele we-spermidine, ake sibheke kabanzi ukuxhumana phakathi kwe-spermidine nempilo yethu!
Ngakho-ke, iyini i-spermidine? Isuselwa egameni lesiGreki elithi "sperma", elisho imbewu, i-spermidine itholakala kabanzi emithonjeni yezitshalo ezifana nobhontshisi, uphizi, amakhowe kanye nokusanhlamvu okuphelele. Itholakala futhi koshizi asebekhulile abaye badlula enkambisweni yokubilisa nokuguga okuholela emazingeni aphezulu e-spermidine.
I-Spermidine iyi-polyamine ye-aliphatic. I-Spermidine synthase (SPDS) ivuselela ukwakheka kwayo kusuka ku-putrescine. Iyisandulela sezinye izinhlobo ze-polyamine ezifana ne-spermine kanye ne-isomer pyrospermine yayo yesakhiwo.
Njenge-polyamine eyenzeka ngokwemvelo, i-spermidine idlala indima ebalulekile emisebenzini ehlukahlukene yamaseli. Itholakala kuzo zonke izinto eziphilayo kusukela kubhaktheriya kuya ezitshalweni nasezilwaneni, futhi itholakala kakhulu emangqamuzaneni abantu.
Ukuthola amazinga anele e-spermidine ngokudla kuphela kuyinselele. Eminyakeni yamuva nje, ucwaningo ngale nhlanganisela yezinto eziphilayo luholele ekukhiqizweni kwezithasiselo ze-spermidine. Lezi zithasiselo zinikeza indlela elula nethembekile yokuqinisekisa ukuthi i-spermidine idliwa ngokwanele, ikakhulukazi kulabo abangase bangakwazi ukufinyelela ukudla okucebile nge-spermidine.
1Thuthukisa ikhono le-autophagy
I-Autophagy inqubo ebangela ukususwa kwezingxenye zamaseli ezonakele noma ezingadingekile futhi ibalulekile ekugcineni impilo nokusebenza kwamaseli.
Kutholakale ukuthi i-Spermidine ikhuthaza i-autophagy, ikhuthaza ukususwa kwezinto eziyingozi kanye nokuthuthukisa ubuqotho bamaseli jikelele. Lokhu, nakho, kuye kwahlotshaniswa nengozi encishisiwe yezifo ezihlobene nokuguga, njengezifo eziwohlokayo zemizwa kanye nezinhlobo ezithile zomdlavuza.
2. Inomphumela othile wokuvikela inhliziyo.
Izifundo eziningana zikhombisile ukuthi i-spermidine ingasiza ekwehliseni umfutho wegazi, inciphise ingozi yesifo senhliziyo, futhi ithuthukise impilo yenhliziyo nemithambo yegazi.
I-Spermidine yenza lokhu ngokuvimbela ukunqwabelana kwamafutha emithanjeni yegazi, ukunciphisa ukuvuvukala nokukhuthaza ukuvuselelwa kwamaseli enhliziyo alimele. Ngokufaka i-spermidine ekudleni kwethu, singazivikela ezifweni ezihlobene nenhliziyo.
3. Ubonisa ithemba ekukhuthazeni impilo yobuchopho.
Ukuguga kuvame ukuhlotshaniswa nokwehla kokusebenza kwengqondo, okuholela ezifweni ezifana ne-dementia kanye nesifo i-Alzheimer's.
Kodwa-ke, i-spermidine yatholakala ukuthi ilwa nale miphumela ngokuvikela ama-neurons ekucindezelekeni kwe-oxidative kanye nokuthuthukisa ukusinda kwawo jikelele.
Izifundo ezifundweni zezilwane zibonise nokuthi ukungezelelwa kwe-spermidine kungalibazisa ukwehla kwenkumbulo nokufunda okuhlobene nobudala. Ngakho-ke, ukusebenzisa amandla e-spermidine kungavula indlela yamasu amasha okuvimbela kanye nokungenelela ezifweni eziwohlokayo zemizwa.
Ngezansi kuneminye imithombo yokudla ephezulu ye-spermidine ongase ufune ukuyicabangela ukuyifaka ekudleni kwakho ukuze wandise ukudla kwakho kwe-spermidine.
1. Igciwane likakolweni
Iqukethe okuqukethwe okuphezulu kwe-spermidine. Ngokuvamile isetshenziswa njengesengezo ku-cereal noma i-yogurt, ukufaka i-wheat germ ekudleni kwakho kwasekuseni kuyindlela elula yokuthola izinzuzo ze-spermidine.
2. Isoya
Akukhona nje kuphela ukuthi isoya iyindlela enhle kakhulu yeprotheyini yemifino, kodwa futhi iqukethe i-spermidine eningi. Ukufaka imikhiqizo yesoya efana ne-tofu, i-tempeh noma i-edamame ekudleni kwakho kuyindlela enhle kakhulu yokwandisa ukudla kwakho le nhlanganisela enenzuzo.
3. Amakhowe
Amakhowe e-Shiitake, amakhowe e-portobello, kanye namakhowe e-oyster acebile kakhulu kule nhlanganisela. Lezi zithako eziguquguqukayo zingasetshenziswa ezitsheni ezahlukahlukene kusukela kuma-stir fries kuya esobho, okunikeza indlela emnandi nenempilo yokwandisa ukusetshenziswa kwe-spermidine.
4. Okunye
Okunye ukudla okucebile nge-spermidine kufaka phakathi ubhontshisi njenge-lentile, ubhontshisi kanye nobhontshisi oluhlaza, kanye nezithelo ezithile njenge-grapefruit, ama-orange kanye nama-pear. Ngokufaka lokhu kudla ekudleni kwakho, ungandisa ngokwemvelo ukudla kwakho i-spermidine futhi mhlawumbe ube nemiphumela yayo ekhuthaza impilo.
Nakuba ucwaningo nge-spermidine lusaqhubeka, imiphumela yokuqala iyathembisa. Kubalulekile ukuqaphela ukuthi amazinga e-spermidine angahluka ngokusekelwe ezicini ezifana nokucubungula ukudla, ukuvuthwa, kanye nendlela yokupheka. Ngakho-ke, ukuze kusetshenziswe kakhulu, kunconywa ukudla lokhu kudla ngezindlela zakho ezintsha nezingasetshenziswanga kahle.
Iningi labantu alicaci kahle ngomehluko phakathi kokuthola i-spermidine ekudleni noma ukusebenzisa izithasiselo ze-spermidine ngqo, ake sibheke umehluko ndawonye!
1Izithasiselo zinikeza indlela elula yokwandisa amazinga e-spermidine, ikakhulukazi kulabo abanenkinga yokuthola okwanele ngokudla kwabo okuvamile. Izithasiselo ze-Spermidine zivame ukuvela emithonjeni yemvelo futhi ziza ngezindlela ezahlukene, njenge-capsules noma i-powder. Lezi zithasiselo zidlula enkambisweni yokugxilisa i-spermidine, okwenza kube lula ukuthola imithamo ephezulu kunokudla kuphela.
2Uma udla ukudla okucebile nge-spermidine, uzuza ngokusebenzisana kwezinye izakhamzimba ezikhona ku-food matrix, okuthuthukisa ukumuncwa kwayo kanye nezinzuzo zezempilo iyonke. Futhi, imithombo yokudla ivame ukunikeza amanani aphansi e-spermidine uma kuqhathaniswa nezithasiselo, kodwa isazuzisa.
3. Lesi sithasiselo sinikeza umthamo ophezulu nojwayelekile we-spermidine, okuvumela indlela eqondiswe kakhulu ngokusekelwe ezidingweni zomuntu ngamunye. Lokhu kuzuzisa kakhulu abantu abafuna izinzuzo ezithile zezempilo ze-spermidine noma abantu abanciphisa ukudla kwabo ukudla okuthile okucebile nge-spermidine ngenxa yemikhawulo yokudla.
Ukukhetha ukuthola i-spermidine ekudleni noma ezithasiseleni kuncike kulokho umuntu akuthandayo kanye nesimo sakhe. Kubantu abaningi, ukudla okulinganiselayo okuhlanganisa ukudla okucebile ku-spermidine kufanele kuhlinzeke ngamazinga afanele ale nhlanganisela enenzuzo. Kodwa-ke, kulabo abafuna amazinga aphezulu noma ababhekene nemikhawulo yokudla, ukwengeza kungaba yinto ewusizo kakhulu.
Ukunquma umthamo ofanele we-spermidine kuncike ezintweni eziningi, okuhlanganisa ubudala, impilo ejwayelekile, kanye nemiphumela ethile efiselekayo.
Okwamanje, akukho ukudla kwansuku zonke okunconywayo (i-RDI) kwe-spermidine. Izifundo zibonisa imiphumela emihle ngemithamo engu-1 kuya ku-10 mg ngosuku. Kodwa-ke, kunconywa njalo ukubonisana nochwepheshe wezempilo ngaphambi kokufaka i-spermidine ohlelweni lwakho lwansuku zonke.
Imithombo yokudla yemvelo inikeza i-spermidine futhi ingaba yinto enhle kakhulu ekudleni kwakho. Ukudla okufana ne-wheat germ, izithelo ezithile (i-grapefruit, amagilebhisi, nama-orange), ushizi, ubhontshisi, amakhowe, ngisho newayini elidala kuqukethe inani elikhulu le-spermidine. Ukufaka lokhu kudla ekudleni okunempilo kungasiza ekwandiseni ukuthathwa kwe-spermidine ngokwemvelo.
Izithasiselo nazo ziyindlela yokukhetha kulabo abafuna ukudla okwengeziwe kwe-spermidine. Izithasiselo ze-Spermidine ziza ngezindlela eziningi, kufaka phakathi ama-capsule kanye nama-powder. Izithasiselo zekhwalithi ephezulu kufanele zivela kubakhiqizi abathembekile abanamathela ezindinganisweni zokulawula ikhwalithi eziqinile.
Uma uqala ukwengezwa kwe-spermidine, kunconywa ukuthi uqale ngomthamo ophansi. Ukuqala cishe ngo-1 mg ngosuku bese ukwandisa umthamo kancane kancane emavikini ambalwa kungasiza ekugwemeni imiphumela emibi engaba khona.
Nakuba i-spermidine ibonakala iphephile futhi ibekezelelwa kahle, abanye abantu bangase babe nemiphumela emincane yesisu njengokuqunjelwa noma ukuphazamiseka kwesisu lapho beqala ukwengeza i-spermidine. Uma lezi zimpawu ziqhubeka noma ziba zimbi kakhulu, kufanele kuxoxwe nochwepheshe wezempilo.
U: Kuthatha isikhathi esingakanani ukuthi i-spermidine isebenze?
A: Isikhathi esithathwa yi-spermidine ukusebenza nokukhiqiza imiphumela ebonakalayo singahluka ngokusekelwe ezicini eziningana, okuhlanganisa iminyaka yomuntu, impilo iyonke, umthamo, kanye nobude besikhathi sokwengeza. Ngokuvamile, ukwengeza okuqhubekayo kwe-spermidine kungadingeka amasonto ambalwa noma ngisho nezinyanga ngaphambi kokuba umuntu aqale ukuqaphela noma yiziphi izinguquko ezibalulekile.
Isixwayiso: Lesi sihloko senzelwe ulwazi kuphela futhi akufanele sibhekwe njengeseluleko sezokwelapha. Njalo xhumana nochwepheshe wezempilo ngaphambi kokusebenzisa noma yiziphi izithasiselo noma ukushintsha uhlelo lwakho lwezempilo.
Isikhathi sokuthunyelwe: Juni-28-2023
