Kubantu abaningi, ukuphatha amazinga aphezulu e-cholesterol kuwukukhathazeka okukhulu. I-cholesterol ephezulu yandisa amathuba okuba nesifo senhliziyo, unhlangothi, nezinye izinkinga zempilo ezingathi sína. Nakuba izinguquko zokuphila ezifana nokudla nokuzivocavoca zingasiza ukwehlisa i-cholesterol, ngezinye izikhathi ukungenelela okwengeziwe kuyadingeka. Okunye ukungenelela okunjalo ukusetshenziswa kwe-niacin, uhlobo lwevithamini B3 oluye lwaboniswa lunomthelela omuhle emazingeni e-cholesterol. Itholakala ekudleni okuhlukahlukene, okuhlanganisa inyama, inhlanzi, izinkukhu, kanye nezinhlamvu eziqinisiwe nezinkwa. Ngaphezu kwendima yayo kumetabolism yamandla, i-niacin iboniswe ukuthi inomthelela omuhle emazingeni e-cholesterol.
I-Niacin, eyaziwa nangokuthi uvithamini B3, owaziwa nangokuthi uvithamini we-niacin kanye ne-nicotinamide, ivithamini encibilika emanzini edlala indima ebalulekile ekusebenzeni komzimba. Kubalulekile ekuguquleni amakhabhohayidrethi, amafutha namaprotheni abe amandla futhi kusiza nasekugcineni isikhumba esinempilo, isimiso sezinzwa kanye nokugaya ukudla.
I-niacin itholakala ekudleni okuhlukahlukene, okuhlanganisa inyama, inhlanzi, amantongomane kanye nezinhlamvu. Ingase futhi ihlanganiswe ngumzimba isuka ku-amino acid tryptophan, nakuba le nqubo inganele ukuhlangabezana nezidingo ze-niacin zansuku zonke zomzimba.
I-Niacin iza ngezinhlobo ezimbili ezivame ukutholakala ekudleni nasezithakweni: i-niacinamide ne-niacin. Zombili lezi zinhlobo ziguqulwa emzimbeni zibe uhlobo olusebenzayo lwe-coenzyme ye-niacin, ebese isetshenziswa ekuphenduleni okuhlukahlukene kwe-metabolic.
I-Niacin iboniswe ukwandisa amazinga e-HDL (enhle) i-cholesterol ngenkathi yehlisa i-cholesterol ye-LDL (embi) ne-triglycerides. Lokhu kwenza kube isakhi esibalulekile sokugcina impilo yenhliziyo nemithambo yegazi nokunciphisa ingozi yesifo senhliziyo.
Ngaphezu kwendima yayo ku-cholesterol metabolism, i-niacin iphinde ibambe iqhaza ekulawuleni amazinga kashukela egazini. Kuyasiza ukuthuthukisa ukuzwela kwe-insulin futhi kunciphise ukuvuvukala.
Kubalulekile ekukhiqizeniNAD(i-nicotinamide adenine dinucleotide) kanye ne-NADP (i-nicotinamide adenine dinucleotide phosphate), okungama-coenzyme ahilelekile ezinqubweni ezihlukahlukene zamaselula, okuhlanganisa ukukhiqizwa kwamandla nokuzivikela kwe-antioxidant .
Okokuqala, i-niacin ibalulekile empilweni yethu yenhliziyo nemithambo yegazi. Isiza ukwehlisa amazinga e-LDL, noma i-cholesterol “embi”, ngenkathi ikhulisa amazinga e-HDL, noma i-cholesterol “enhle”. Lokhu kungaba nomthelela omuhle empilweni yethu yenhliziyo futhi kunciphise ingozi yezifo zenhliziyo nemithambo yegazi njengesifo senhliziyo nesifo sohlangothi. Ukwengeza, i-niacin ikhonjiswe ukwehlisa amazinga e-triglyceride, nakho okuhle nempilo yethu yenhliziyo.
Ukwengeza, i-niacin idlala indima ebalulekile ekukhiqizeni amandla emzimbeni. Kuhileleke ohlelweni lokuguqula ama-carbohydrate abe yi-glucose, umthombo oyinhloko wamandla amangqamuzana ethu. Lokhu kusiza ukulwa nemizwa yokukhathala futhi kuthuthukisa wonke amazinga wamandla, okwenza i-niacin ibe isakhi esibalulekile sokugcina amandla nokubekezela.
Enye inzuzo ebalulekile ye-niacin indima yayo ekusekeleni isimiso sezinzwa esinempilo. Ihilelekile ekukhiqizeni ama-neurotransmitters, amakhemikhali asiza ukudlulisa izimpawu phakathi kwamangqamuzana ezinzwa. Lokhu kungaba nomthelela omuhle esimweni sethu semizwa, ukusebenza kwengqondo, kanye nempilo yengqondo iyonke.
I-Niacin nayo inezindawo zokulwa ne-antioxidant ezisiza ukulwa nengcindezi ye-oxidative nokunciphisa ukuvuvukala emzimbeni. Lokhu kungaba nomthelela omuhle empilweni yethu iyonke futhi kungase kusize ukunciphisa ingozi yezifo ezingamahlalakhona njengomdlavuza nesifo sikashukela. Ukwengeza, i-niacin iboniswe ukuthi inomthelela omuhle empilweni yesikhumba, isiza ukunciphisa ukubukeka kwe-acne futhi ikhuthaze ibala elicacile nelinempilo.
Ukwengeza, i-niacin ibalulekile ekusebenzeni kahle kohlelo lokugaya ukudla. Isiza ukusekela ukukhiqizwa kwama-enzyme okugaya, abalulekile ekuhlakazeni ukudla nokumunca imisoco. Lokhu kungaba nomthelela omuhle empilweni yethu yonke yokugaya futhi kungasiza ekudambiseni izimpawu ezifana nokuqunjelwa nokuqunjelwa.
Ngaphezu kwalezi zinzuzo, i-niacin iboniswe ukuthi inomphumela omuhle ekuzweleni kwe-insulin, okubalulekile ekulawuleni amazinga kashukela egazini kanye nokunciphisa ingozi yesifo sikashukela. Iphinde ibambe iqhaza ekusekeleni ukusebenza kwamalunga okunempilo futhi ingasiza ekwehliseni izimpawu ze-arthritis nokunye ukuvuvukala.
I-Niacin ibhekwa njengendlela ebalulekile yokusiza i-cholesterol ephansi, futhi ucwaningo oluningi luye lwabonisa ukuthi i-niacin inganciphisa ngempumelelo amazinga e-LDL cholesterol, eyaziwa ngokuthi "i-cholesterol embi". Kuye kwaboniswa futhi ukwandisa amazinga e-HDL cholesterol (evame ukubizwa ngokuthi "i-cholesterol enhle"). Kodwa i-niacin iyifinyelela kanjani le miphumela?
Enye yezindlela i-niacin esiza ngayo ukwehlisa i-cholesterol iwukuvimbela ukukhiqizwa kwesibindi kwe-low-density lipoprotein cholesterol, isandulela se-low-density lipoprotein cholesterol. Lokhu kusho ukuthi isibindi sikhiqiza i-cholesterol encane ye-LDL, okuholela emazingeni aphansi e-LDL cholesterol egazini. I-Niacin isiza futhi ukukhulisa umsebenzi we-lipoprotein lipase, i-enzyme esiza ukudiliza i-triglycerides (olunye uhlobo lwamafutha egazini). I-Niacin yehlisa ngokungaqondile amazinga e-cholesterol e-LDL ngokunciphisa i-VLDL namazinga e-triglyceride.
I-Niacin nayo ingakhuphula amazinga e-HDL e-cholesterol. I-HDL cholesterol isiza ekukhipheni i-cholesterol ye-LDL egazini, iyithuthe iye esibindini lapho ingaphulwa khona futhi ikhishwe emzimbeni. Yingakho i-cholesterol ye-HDL ivame ukubizwa ngokuthi i-cholesterol "enhle" ngoba isiza ukuvimbela ukunqwabelana kwe-plaque emithanjeni, okungaholela esifweni senhliziyo.
Ngaphezu kwemiphumela yayo emazingeni e-cholesterol, i-niacin itholakale inezinye izinzuzo zenhliziyo nemithambo yegazi. Kungasiza ukunciphisa ukuvuvukala emithanjeni, isici esibalulekile ekuthuthukiseni i-atherosclerosis, noma ukuqina kwemithambo. I-Niacin iye yaboniswa ukuthuthukisa umsebenzi wamangqamuzana e-endothelial (ulwelwesi lwemithambo yegazi), esiza ukuthuthukisa ukugeleza kwegazi nokunciphisa ingozi yamahlule egazi. Ngaphezu kwalokho, i-niacin ingakwazi ukulinganisa amazinga kashukela egazini futhi isize ukulawula isifo sikashukela.
I-Niacin, eyaziwa nangokuthi i-vitamin B3, iyisakhi esibalulekile. Ibalulekile emisebenzini ehlukahlukene yomzimba, okuhlanganisa i-metabolism, ukusebenza kwezinzwa, nokukhiqizwa kwamandla kwamangqamuzana. Ukufaka ukudla okunothe nge-niacin ekudleni kwakho kulula ngoba kunezinhlobonhlobo zokudla okuqukethe inani elikhulu lalesi sakhi esibalulekile. Okunye ukudla okucebile nge-niacin kufaka:
1. Inkukhu
Inkukhu ingumthombo omkhulu we-niacin kanye namaprotheni angenalutho. Kungakhathaliseki ukuthi ukhetha inkukhu eyosiwe, ebhakiwe, noma eyosiwe, ukufaka le nyama engenamafutha ekudleni kwakho kuyindlela enhle yokwandisa ukudla kwakho kwe-niacin.
2. I-tuna
Akukhona nje kuphela ukuthi i-tuna ingumthombo omkhulu we-niacin, kodwa futhi inothe ngama-Omega-3 fatty acids, abalulekile empilweni yenhliziyo. Ukwengeza i-tuna kumasaladi, amasemishi, noma ama-sushi rolls kuyindlela ehlakaniphile yokwandisa ukudla kwakho kwe-niacin.
3. Amakinati
Amantongomane awukudla okumnandi futhi okulula okunothe nge-niacin. Kungakhathaliseki ukuthi ukhetha amantongomane aluhlaza, agazingiwe noma ebhotela lamantongomane, ukwengeza amantongomane ekudleni kwakho kuyindlela elula yokuthola i-niacin eyengeziwe.
4. Amakhowe
Akukhona nje ukuthi amakhowe awumthombo omkhulu we-niacin, futhi ane-calorie ephansi futhi aphezulu kuma-antioxidants. Ukwengeza amakhowe esobho, amasaladi, noma ama-stir-fries kuyindlela enhle yokuthola i-niacin eyengeziwe ekudleni kwakho.
5. Ubhontshisi oluhlaza
Akukhona nje ukuthi uphizi oluhlaza ungumthombo omuhle we-niacin, kodwa futhi ucebile ku-fibre, amaprotheni, namanye amavithamini namaminerali abalulekile. Ukwengeza uphizi oluhlaza ekudleni kwakho kuyindlela enhle yokwandisa ukudla kwakho kwe-niacin ngenkathi ukhulisa ukudla kwakho konke okunomsoco.
6. Imbewu kabhekilanga
Imbewu kabhekilanga iyisidlo esinomsoco esigcwele i-niacin, uvithamini E, i-magnesium nezinye imisoco ebalulekile. Ukudla imbewu kabhekilanga phakathi kokudla kuyindlela enhle yokwandisa ukudla kwakho kwe-niacin ngenkathi wenelisa indlala.
Ngaphezu kwalokhu kudla okunothe nge-niacin, kuneminye imithombo eminingi ye-niacin ongayifaka ekudleni kwakho, njenge-salmon, ukwatapheya, nezinhlamvu eziphelele. Ngokufaka okunhlobonhlobo kwalokhu kudla ekudleni nasekudleni kwakho okulula, ungaqinisekisa ukuthi uthola amanani anele e-niacin ukusekela impilo yakho yonke kanye nokuphila kahle.
I-Niacin, eyaziwa nangokuthi i-vitamin B3, isakhi esibalulekile esidlala indima ebalulekile ekugcineni impilo. Ihilelekile ezinqubweni ezihlukahlukene zomzimba, okuhlanganisa i-metabolism, ukulungiswa kwe-DNA, nokuhlanganiswa kwamahomoni. Nakuba i-niacin yenzeka ngokwemvelo ekudleni okuningi, abanye abantu bangadinga izithasiselo ezengeziwe ukuze bahlangabezane nezidingo zabo zansuku zonke.
Uma ucabanga ukuthatha izithasiselo ze-niacin, kubalulekile ukukhetha unolwazi ngempilo yakho. Kunezici ezimbalwa ezibalulekile okufanele uzicabangele lapho unquma ukuthi izithasiselo ze-niacin zikulungele yini
Okokuqala, kubalulekile ukuqonda izinzuzo ezingaba khona ze-niacin supplementation. I-Niacin iye yacwaningwa ngamandla ayo okuthuthukisa amazinga e-cholesterol, ukunciphisa ingozi yesifo senhliziyo nemithambo yegazi, ngisho nokwenza ngcono ukusebenza kobuchopho. Ukwengeza, i-niacin inezici zokulwa nokuvuvukala ezingasiza ekunciphiseni ubungozi bezifo ezithile ezingamahlalakhona.
Kodwa-ke, kubalulekile futhi ukucabangela izingozi ezingase zibe khona kanye nemiphumela engemihle ye-niacin supplementation, futhi kubalulekile ukuxoxa ngohlelo lwakho lokuthatha izithasiselo ze-niacin nomhlinzeki wakho wokunakekelwa kwezempilo ukuze uqinisekise ukuthi liphephile futhi likulungele.
Ukwengeza, kubalulekile ukukhetha isithasiselo sekhwalithi ephezulu se-niacin emthonjeni onedumela elihle. Akuzona zonke izithasiselo ezidalwe zilingana, ngakho-ke kubalulekile ukukhetha umkhiqizo wekhwalithi kumkhiqizo onedumela elihle, okungcono kakhulu okhiqizwa endaweni ethobela izindinganiso eziqinile zokulawula ikhwalithi. Ukwengeza, ungase uthande ukucabangela ukubheka izithasiselo eziye zahlolwa ezivela eceleni, njengoba lokhu kuqinisekisa ukuthi amandla nokuhlanzeka komkhiqizo kuqinisekiswe ngokuzimele. Lokhu kungasiza ukuqinisekisa ukuthi uthola umkhiqizo ophephile futhi osebenzayo.
Lapho ukhetha isithasiselo se-niacin, kubalulekile futhi ukucabangela uhlobo lwe-niacin olusetshenziswa ekwengezeni.
1. I-Niacin: Lolu uhlobo oluvame kakhulu lwe-niacin olutholakala ezithasiselweni. Yaziwa ngekhono layo lokusekela impilo yenhliziyo nemithambo yegazi ngokusiza ukwehlisa amazinga e-cholesterol nokuthuthukisa ukujikeleza kwegazi. Kodwa-ke, abanye abantu bangase babe nokuguquguquka kwesikhumba noma ububomvu besikhashana njengomphumela ongaseceleni wokuphuza i-niacin.
2. I-Niacinamide: Eyaziwa nangokuthi i-niacinamide, lolu hlobo lwe-niacin ludumile ngezinzuzo zalo ezingaba khona zesikhumba. Ivame ukusetshenziswa emikhiqizweni yokunakekelwa kwesikhumba ukusiza ukuthuthukisa ukubukeka kwemigqa emihle, imibimbi, kanye nezinduna. I-Niacinamide nayo inenzuzo ekusekeleni ukusebenza komzimba wonke kanye nempilo yomqondo.
3. Inositol hexanicotinate: Lena inhlanganisela ye-niacin ne-myo-inositol, utshwala obushukela. I-Inositol hexanicotinate ivame ukusetshenziselwa ukusekela uhlelo lokujikeleza okunempilo futhi ingasiza ekugcineni amazinga e-cholesterol enempilo.
Inkampani engu-Suzhou Myland Pharm & Nutrition Inc. ibambe iqhaza ebhizinisini lezithako zokudla okunomsoco kusukela ngo-1992. Yinkampani yokuqala eShayina ukuthuthukisa nokudayisa imbewu yamagilebhisi.
Njengoba inesipiliyoni seminyaka engu-30 futhi iqhutshwa ubuchwepheshe obuphezulu kanye namasu e-R&D athuthukiswe kakhulu, inkampani ithuthukise uhla lwemikhiqizo encintisanayo futhi yaba isithasiselo sesayensi yempilo emisha, ukuhlanganisa ngokwezifiso kanye nenkampani yezinkonzo zokukhiqiza.
Ngaphezu kwalokho, inkampani iphinde ibe ngumkhiqizi obhalisiwe we-FDA, oqinisekisa impilo yabantu ngekhwalithi ezinzile nokukhula okuqhubekayo. Izinsiza ze-R&D zenkampani kanye nezindawo zokukhiqiza kanye namathuluzi okuhlaziya kungokwesimanje futhi anemisebenzi eminingi, futhi ayakwazi ukukhiqiza amakhemikhali esikalini se-milligram kuya kuthani ngokuhambisana namazinga e-ISO 9001 kanye nezinqubo zokukhiqiza ze-GMP.
Q: Iyini i-niacin futhi isebenza kanjani ukwehlisa amazinga e-cholesterol?
A: I-Niacin, eyaziwa nangokuthi i-vitamin B3, ivithamini encibilika emanzini ekhonjiswe ukuthi yehlisa i-cholesterol ye-LDL (embi) namazinga e-triglyceride ngenkathi ikhulisa amazinga e-cholesterol e-HDL (enhle). Isebenza ngokuvimbela ukukhiqizwa kwesibindi kwe-cholesterol ne-triglycerides.
Umbuzo: Ingabe i-niacin iyasebenza ekwehliseni amazinga e-cholesterol?
A: Yebo, i-niacin ifakazelwe ukuthi iyasebenza ekwehliseni amazinga e-cholesterol, ikakhulukazi i-LDL cholesterol kanye ne-triglycerides. Ingase futhi inyuse amazinga e-HDL e-cholesterol, enenzuzo empilweni yenhliziyo.
Q: Ingakanani i-niacin okufanele ithathwe ukwehlisa amazinga e-cholesterol?
A: Umthamo ofanele we-niacin wokwehlisa amazinga e-cholesterol uyahlukahluka kuye ngezici ngazinye ezifana neminyaka, ubulili, kanye nempilo iyonke. Kubalulekile ukusebenzisana nochwepheshe bezempilo ukuze uthole umthamo ofanele wena.
Umshwana wokuzihlangula: Lesi sihloko esolwazi oluvamile kuphela futhi akufanele sithathwe njengeseluleko sezokwelapha. Olunye ulwazi lokuthunyelwe kwebhulogi luvela ku-inthanethi futhi alusebenzi. Le webhusayithi inomthwalo wemfanelo kuphela wokuhlunga, ukufometha kanye nokuhlela ama-athikili. Injongo yokudlulisa ulwazi olwengeziwe ayisho ukuthi uyavumelana nemibono yayo noma uqinisekise ubuqiniso bokuqukethwe kwayo. Hlala uthintana nochwepheshe bezempilo ngaphambi kokusebenzisa noma yiziphi izithasiselo noma wenze izinguquko ohlelweni lwakho lokunakekelwa kwezempilo.
Isikhathi sokuthumela: Jan-02-2024
