Umkhiqizi wempuphu we-Beta-Nicotinamide Adenine Dinucleotide(NAD+) Inombolo ye-CAS: 53-84-9 Ubumsulwa obungu-98.5% obuncane bezithako zesengezo Isithombe Esifakiwe

Umkhiqizi wempuphu we-Beta-Nicotinamide Adenine Dinucleotide(NAD+) Inombolo ye-CAS: 53-84-9 98.5% ubumsulwa obuncane bezithako ezengeziwe

Incazelo emfushane:

I-NAD+, noma i-nicotinamide adenine dinucleotide, iyi-coenzyme etholakala kuwo wonke amaseli aphilayo. Idlala indima ebalulekile ekusetshenzisweni kwamaseli, ikakhulukazi ekusetshenzisweni kwe-redox, okubandakanya ukudluliselwa kwama-electron phakathi kwama-molecule. I-NAD+ ihilelekile kokubili ekusetshenzisweni kwe-anabolic kanye ne-catabolic, okwenza kube yingxenye ebalulekile yokusetshenziswa kwamandla.

Sithumelele i-imeyili

Imininingwane Yomkhiqizo

Amathegi Omkhiqizo

Amapharamitha Omkhiqizo

Igama lomkhiqizo	I-Nicotinamide Mononucleotide
Elinye igama	I-RIBOTIDE YE-NICOTINAMIDE; I-BETA-Nicotinamide Mononucleotide； I-Ribonucleotide ye-NicotinaMide; i-β-Nicotinamide Mononucleotide ()
Inombolo ye-CAS	1094-61-7
Ifomula yama-molecule	C11H15N2O8P
Isisindo sama-molecule	334.22
Ubumsulwa	98.0%
Ukubukeka	Impuphu emhlophe
Ukupakisha	1kg/isikhwama 10kg/isigubhu
Isicelo	Ukulwa nokuguga

Isingeniso somkhiqizo

I-Beta-Nicotinamide Adenine Dinucleotide (Beta-NAD+), eyaziwa kakhulu ngokuthi i-Beta-NAD, iyi-molecule ebalulekile etholakala kuwo wonke amaseli aphilayo. Idlala indima ebalulekile ezinqubweni ezahlukene zezinto eziphilayo, okuhlanganisa i-metabolism yamandla kanye nokubonisana kwamaseli. I-Beta-Nicotinamide Adenine Dinucleotide yenziwa kusuka ku-niacin (i-vitamin B3) kanye ne-ATP (i-adenosine triphosphate) ngochungechunge lwezimpendulo ze-enzyme. Ngesikhathi sokuphefumula kwamaseli, i-Beta-Nicotinamide Adenine Dinucleotide iyi-coenzyme esisiza ukudluliselwa kwama-electron ngesikhathi sokuqhekeka kwe-glucose kanye namanye ama-biomolecule. Lokhu kudluliselwa kwama-electron kubalulekile ekukhiqizeni i-ATP, imali yamandla yeseli jikelele. Ngaphandle kwe-Beta-Nicotinamide Adenine Dinucleotide, amaseli awakwazi ukukhiqiza amandla ngempumelelo futhi enze imisebenzi yawo ebalulekile. Ngaphezu kwendima yayo ekusetshenzisweni kwamandla, i-Beta-Nicotinamide Adenine Dinucleotide isebenza njengesisekelo sama-enzyme ahlukahlukene ahilelekile ekuboniseni nasekulawuleni amaseli. Iqembu elilodwa elaziwayo lama-enzyme asebenzisa i-Beta-Nicotinamide Adenine Dinucleotide yi-Sirtuins, ehilelekile ezinqubweni ezahlukahlukene zamaseli, okuhlanganisa ukulungiswa kwe-DNA, ukuvezwa kwezakhi zofuzo, kanye nokuguga. Lawa ma-enzyme adinga i-Beta-Nicotinamide Adenine Dinucleotide njenge-cofactor ukuze asebenzise umsebenzi wawo we-enzyme.

Isici

(1) Ubumsulwa obuphezulu: I-NAD+ ingathola imikhiqizo yobumsulwa obuphezulu ngezinqubo zokukhiqiza zokucwenga. Ubumsulwa obuphezulu busho ukutholakala okungcono kwe-bioavailability kanye nokusabela okuncane okubi.

(2) Ukuphepha: Ukuphepha okuphezulu, ukusabela okungekuhle okumbalwa.

(3) Ukuzinza: I-NAD+ inokuqina okuhle futhi ingagcina umsebenzi wayo kanye nomphumela ngaphansi kwezimo ezahlukene zokugcinwa.

Izicelo

I-NAD+ iyi-coenzyme edlala indima ebalulekile ezinqubweni ezahlukahlukene zezinto eziphilayo, okuhlanganisa ukwakheka kwamandla, ukulungiswa kwe-DNA, kanye nokubonisana kwamaseli. I-NAD+ ibandakanyeka nakwezinye izinqubo zamaseli njengokulungiswa kwe-DNA, ukuvezwa kwezakhi zofuzo, kanye nokubonisana kwe-calcium. Kubalulekile ekugcineni ukuguga okunempilo, njengoba amazinga e-NAD+ ehla ngokuguga, okuholela ekunciphiseni ukwakheka kwamaseli kanye nokwanda komonakalo wamaseli. Amazinga e-NAD+ ayancipha ngokuguga, futhi lokhu kwehla kuhlotshaniswa nezifo ezihlobene nokuguga. Ukwengeza nge-NAD+ precursors kuye kwabonakala kukhulisa amazinga e-NAD+ futhi kunemiphumela emihle yokuguga.