Kusukela ekuxazululeni izinkinga kuya ekuthatheni izinqumo, sidinga ukwazi ukuqonda, ukuhlaziya nokuhumusha ulwazi ngempumelelo. Njengoba ubuchwepheshe nocwaningo lwesayensi luthuthuka, amathuba okuthuthukisa amakhono ethu okuqonda ayakhula, okuholela emiphumeleni emangalisayo.
Amakhono okuqonda athuthukisiwe angaba nomthelela kuzo zonke izici zokuphila kwethu, okuhlanganisa imfundo, ukukhula kochwepheshe kanye nokuthuthuka komuntu siqu. Umuntu onamakhono okuqonda athuthukisiwe angakwazi ukubamba imiqondo ngokushesha, agcine ulwazi, futhi alusebenzise ezimweni ezintsha. Lokhu-ke kukhombisa amazinga aphezulu okusungula, ukucabanga okujulile kanye namakhono okuxazulula izinkinga.
Ngaphezu kwalokho, abantu abathuthukisa amakhono okuqonda emsebenzini bavame ukwenza kahle emisebenzini yabo. Zisebenza kahle futhi zivumelana nezimo, zikwazi ukuphatha imisebenzi eyinkimbinkimbi. Ukunaka kwabo okujulile emininingwaneni kubavumela ukuthi benze ukuxhumana okunengqondo futhi bahlaziye ulwazi ngokunemba.
Ucwaningo luye lwabonisa ukuthi abantu abanamakhono okuqonda athuthukisiwe banokulawulwa okungcono kwemizwa nokuqina. Bangakwazi ukuphatha ngempumelelo ukucindezeleka, ukukhathazeka, nokudangala ngokusebenzisa amasu okuqonda ukuze bahlele kabusha imicabango engemihle futhi bahlele kabusha imibono yezimo eziyinselele.
Nokho, kuyadingeka ukuphatha ukuthuthukiswa kwengqondo ngokuqapha. Nakuba intuthuko kwezobuchwepheshe inikeze inqwaba yamathuluzi nesofthiwe ukuthuthukisa amakhono okuqonda, kubalulekile futhi ukugcina ibhalansi. Ubuchopho bomuntu buyisitho esiyinkimbinkimbi, futhi ukuthembela ngokweqile kwezobuchwepheshe kungalimaza amakhono ethu emvelo okuqonda. Kubalulekile ukuqhubeka nemisebenzi esebenzisa ingqondo ngokwemvelo, njengokufunda, ukufunda amakhono amasha, nokugcina ukuxhumana nabantu.
I-Sunifiram, eyaziwa nangokuthi i-DM-235, iyinhlanganisela ye-nootropic engeyesigaba se-ampakin futhi iphuma ku-piracetam. Eyasungulwa ekuqaleni abacwaningi baseJapane, i-Sunifiram isiye yathandwa ngenxa yezakhiwo zayo ezithuthukisa ukuqonda. Isakhiwo sifana nezinye izinhlanganisela ezifana ne-piracetam ne-aniracetam, kodwa inendlela eyingqayizivele yokwenza.
I-Sunifiram isebenza ngokuyinhloko ngokukhomba ama-receptors athile ebuchosheni abizwa ngokuthi ama-AMPA receptors. Ngokubophezela nokwandisa umsebenzi walawa ma-receptors, i-Sunifiram ithuthukisa ukukhululwa kwe-glutamate, i-neurotransmitter ehilelekile ekufundweni nasekukhumbuleni inqubo. Lokhu kwanda kokukhululwa kwe-glutamate kukholakala ukuthi kunesibopho semiphumela ye-nootropic ye-Sunifiram.
1. Thuthukisa ukugxilisa ingqondo
Ithuthukisa ukugxila futhi ithuthukise ukugxila. Ngokugqugquzela ukukhululwa kwe-glutamate, i-neurotransmitter ejabulisayo, yenza ubuchopho bukwazi ukucubungula ulwazi ngokuphumelelayo. Lokhu kugxila okujulile kungakhuphula kakhulu ukukhiqiza nokucaca komcabango, futhi ngenxa yalokho, abantu ngabanye bangase bathole ukukhiqiza okuthuthukile nokusebenza kwengqondo kukonke.
2. Thuthukisa inkumbulo nekhono lokufunda
I-Sunifiram ineamandla okuthuthukisa inkumbulo nokuthuthukisa ukufunda. Ucwaningo luphakamisa ukuthi kungase kukhuthaze amandla esikhathi eside, inqubo eyisisekelo yokwakheka kwenkumbulo kanye ne-synaptic plasticity, ethuthukisa ukugcinwa kwenkumbulo futhi ithuthukise ikhono lethu lokufunda nokucubungula ulwazi ngempumelelo. Ucwaningo lubonisa ukuthi Sunifiramingase ithuthukise inkumbulo ngokwandisa ukukhululwa kwe-acetylcholine, i-neurotransmitter ebalulekile ekusebenzeni kwenkumbulo.
3. Ithuthukisa amandla engqondo namandla
Ezweni lethu elisheshayo, ukukhathala kwengqondo kuvame kakhulu. Ngamandla okuthuthukisa amazinga wamandla engqondo namandla, i-sunifiram inesithembiso esihle kulabo abafuna ukulwa nokukhathala nokugcina izingqondo zabo zibukhali. Ngokuvuselela ama-glutamate receptors, i-Sunifiram ithuthukisa i-metabolism yamandla ebuchosheni, iqhubeke nokugqugquzela ukuqapha kwengqondo nokuthuthukisa ukusebenza kwengqondo okuphelele.
4. I-Mood Lift & Motivation
Izinzuzo ze-Sunifiram azikhawulelwe ekuthuthukiseni ingqondo; le nhlanganisela ingase ibe nomthelela omuhle emazingeni ethu emizwelo nasezinkuthazweni. Kukholakala ukuthi yenza kusebenze ama-dopamine receptors ebuchosheni ahlotshaniswa nenjabulo kanye nogqozi. Ngenxa yalokho, abantu bangase bazizwe bekhushulwa ugqozi, isimo sengqondo esithuthukisiwe, nokuzimisela okukhulu ukuhlanganyela emisebenzini eyinselele.
5. Amandla e-Neuroprotective
Ngaphandle kwezinzuzo zayo zokuqonda, i-Sunifiram nayo inamandla okuvikela amangqamuzana ezinzwa emonakalweni obangelwa ukucindezeleka okwenziwe nge-oxidative noma ukwehla kwengqondo okuhlobene nobudala. Ngokugqugquzela ukukhiqizwa kwe-nerve growth factor (NGF) kanye ne-brain-derived neurotrophic factor (BDNF), i-Sunifiram ingase ibonise izakhiwo ze-neuroprotective, ngaleyo ndlela ikhuthaze ukusebenza kobuchopho obunempilo nokwandisa isikhathi sokuphila.
Ukuqhathanisa i-Sunifiram namanye ama-nootropics afana ne-Modafinil, i-Aniracetam, ne-Noopept yembula ukufana nokuhluka okuthile.
I-Modafinil ivame ukusetshenziselwa ukwelapha i-narcolepsy kanye nokuphazamiseka kokulala, futhi ivame ukusetshenziswa ngaphandle kwelebula njengesithuthukisi sokuqonda. Nakuba ingaqabula ingqondo futhi ithuthukise ukugxila kwayo, iqondise ngokuyinhloko ama-neurotransmitters akhuthaza ukuvuka kobuchopho, ishiye eminye imisebenzi yengqondo ingathinteki.
I-Sunifiram, ngakolunye uhlangothi, iklanyelwe ngokukhethekile ukuthuthukisa inkumbulo nokufunda. Ukugxila kwayo kuma-glutamate receptors kuyivumela ukuthi ithuthukise imisebenzi yayo eyisisekelo yokuqonda. Lokhu kwenza i-Sunifiram ibe yisinqumo esifanele kubantu abahlose ukuthuthukisa inkumbulo iyonke kanye namakhono okuqonda.
I-Aniracetam ingenye i-nootropic ethandwayo esebenza kuma-acetylcholine receptors ebuchosheni, okuthuthukisa ukugxila nokucaca komcabango. Nakuba i-Sunifiram ingenakho ukusebenzisana okuqondile nama-acetylcholine receptors, isenzo sayo kuma-receptors e-glutamate kuye kwabikwa ukuthi sithuthukise isikhathi sokunaka kanye nomsebenzi wokuqonda jikelele, okwenza kube okunye okubalulekile.
I-Noopept isanda kufika emhlabeni we-nootropic, owaziwa ngezakhiwo zayo ze-neuroprotective. Ikhuthaza impilo yobuchopho ngokuthuthukisa i-nerve growth factor (NGF), edlala indima ebalulekile ekugcinweni nasekukhuleni kwama-neurons. I-Sunifiram, nakuba ingahlobene ngokuqondile nokukhuthazwa kwe-NGF, ingase isekele ngokungaqondile impilo yobuchopho ngemiphumela yayo kuma-receptors e-glutamate.
Ukwengeza, imiphumela ye-Sunifiram ivame ukuhlala isikhathi esifushane, ithuthukisa ukusebenza kwengqondo phakathi namahora ambalwa. Lokhu kungabonakala njengokuhle nokubi, njengoba kuvumela abantu ukuba bathole intuthuko esheshayo ekusebenzeni kwengqondo, kodwa kungase kudinge ukudoswa kwemithi njalo ukuze bathole izinzuzo eziqhubekayo.
I-Sunifiram iyinhlanganisela entsha ngokuqhathaniswa nokucwaninga okulinganiselwe ngemiphumela yayo yesikhathi eside nokuphepha. Kodwa-ke, imibiko ye-anecdotal evela kubasebenzisi igqamisa eminye imiphumela emibi engaba khona okufanele icatshangelwe.
Omunye wemiphumela emibi kakhulu ubuhlungu bekhanda. Abanye abantu baphathwa yikhanda elithambile noma elinzima ngemva kokuthatha i-Sunifiram. Lokhu kungabangelwa umphumela onamandla ovuselelayo wenhlanganisela ohlelweni lwezinzwa. Uma uzwa ubuhlungu bekhanda ngenkathi usebenzisa i-Sunifiram, kutuswa ukuthi unciphise umthamo wakho noma uyeke ukuyisebenzisa ngokuphelele.
Omunye umphumela ongase ube khona we-Sunifiram ukukhathazeka noma ukungahlaliseki. Abanye abasebenzisi babika ukuthi bazizwa be-jittery noma becindezelekile ngemuva kokuthatha lesi sithako. Lokhu kungase kube ngenxa yekhono lika-Sunifiram lokwandisa ukukhululwa nokuthatha ama-neurotransmitters athile ebuchosheni, njenge-glutamate. Uma ujwayele ukukhathazeka noma unomlando wokuphazamiseka kokukhathazeka, kuyalulekwa ukuthi usebenzise i-Sunifiram ngokuqapha noma uthintane nochwepheshe bezempilo ngaphambi kokusetshenziswa.
Omunye umphumela ohlangothini olubikwe abanye abasebenzisi be-Sunifiram ukuqwasha noma inkinga yokulala. Izici ezivuselelayo zalesi sithako zingaphazamisa amaphethini okulala, kwenze kube nzima ukulala noma ukulala ubusuku bonke.
Ezimweni ezingavamile, abantu baye babika izinkinga zokugaya ukudla okufana nesisu esibuhlungu noma isifo sohudo ngemva kokuthatha i-Sunifiram. Nakuba le miphumela engemihle ingavamile, akufanele ishaywe indiva. Uma uhlangabezana nokucindezeleka kwesisu okuphikelelayo ngenkathi usebenzisa lesi sakhi, kuyalulekwa ukuthi uyeke ukusebenzisa futhi uxhumane nochwepheshe bezempilo ukuze ukhiphe noma yiziphi izinkinga zezokwelapha ezicashile.
Ekuphetheni, ngenkathi i-Sunifiram ingase inikeze izinzuzo ezingase zibe khona zokucabangela, umuntu kufanele aqaphele imiphumela emibi engase ibe khona. Lokhu kuhlanganisa ubuhlungu bekhanda, ukukhathazeka noma ukungahlaliseki, inkinga yokulala nezinkinga zokugaya ukudla. Uma ucabangela i-Sunifiram, kuhle ukuthi uqale ngethamo eliphansi futhi ubuke impendulo yomzimba wakho ngokucophelela. Ukubonisana nochwepheshe bezokunakekelwa kwempilo kuhlale kunconywa, ikakhulukazi uma unanoma yiziphi izimo zezokwelapha ezivele zikhona noma uthatha eminye imithi. Njenganoma yisiphi isidakamizwa se-nootropic noma isengezo, ukusetshenziswa okunesibopho kanye nokuzazi komuntu siqu kuyisihluthulelo sokufeza ukuthuthukiswa okufunayo kwengqondo ngenkathi kunciphisa imiphumela emibi engaba khona.
Q:Isebenza kanjani i-Sunifiram?
A:I-Sunifiram kukholakala ukuthi isebenza ngokwandisa umsebenzi wama-neurotransmitters ebuchosheni, njenge-acetylcholine ne-glutamate. Kungase futhi kuthuthukise ukukhululwa kwe-GABA, i-neurotransmitter enesibopho sokunciphisa ukukhathazeka nokuthuthukisa umuzwa wokuzola.
Q:Kuthatha isikhathi esingakanani ukuthi i-Sunifiram ibonise imiphumela?
A:Ukuqala kwemiphumela kungahluka kumuntu nomuntu. Abanye abantu bangase babe nemiphumela ephawulekayo phakathi nesikhathi esifushane, kanti abanye bangadinga isikhathi eside sokusetshenziswa okungaguquki. Kubalulekile ukuba nesineke futhi unikeze inhlanganisela isikhathi esanele sokusebenzisa imiphumela engase ibe khona yokuthuthukisa ingqondo.
Umshwana wokuzihlangula: Lesi sihloko senzelwe izinjongo zokwaziswa kuphela futhi akufanele sithathwe njengeseluleko sezokwelapha. Hlala uthintana nochwepheshe bezempilo ngaphambi kokusebenzisa noma yiziphi izithasiselo noma ukushintsha uhlobo lwakho lokunakekelwa kwezempilo.
Isikhathi sokuthumela: Aug-07-2023
