Umkhiqizi wempuphu ye-Sunifiram Inombolo ye-CAS: 314728-85-3 Ubumsulwa obungu-99% okungenani bezithako ezengeziwe
Ividiyo Yomkhiqizo
Amapharamitha Omkhiqizo
| Igama lomkhiqizo | I-Sunifiram |
| Elinye igama | 1-(4-Benzoylpiperazin-1-yl)propan-1-one; 1-Benzoyl-4-(1-oxopropyl)piperazine |
| Inombolo ye-CAS | 314728-85-3 |
| Ifomula yama-molecule | C14H18N2O2 |
| Isisindo sama-molecule | 246.30 |
| Ubumsulwa | 99.0% |
| Ukubukeka | i-powder emhlophe ekristalu |
| Ukupakisha | 1kg/isikhwama |
| Isicelo | izidakamizwa ze-nootropic |
Isingeniso somkhiqizo
I-Sunifiram iyi-agonist ye-AMPA receptor ethuthukisa ukudlulisa izimpawu kuma-receptor e-AMPA ebuchosheni, okucatshangwa ukuthi adlala indima ebalulekile ekufundeni nasekukhumbuleni. Ngokuthuthukisa umsebenzi wama-receptor e-AMPA, i-Sunifiram kucatshangwa ukuthi ithuthukisa amakhono okufunda nokukhumbula ebuchosheni, ngenkathi ithuthukisa nokugxilisa ingqondo namandla engqondo. Ngaphezu kwalokho, isebenza ngokuvuselela umsebenzi wama-receptor e-glutamate nokwandisa ukukhiqizwa nokukhululwa kwe-acetylcholine "yokufunda i-neurotransmitter". I-Sunifiram isebenza ngokuyinhloko njengesici se-ampa, okusho ukuthi ibopha kuma-receptor e-glutamate ohlobo lwe-AMPA ebuchosheni ngemva kokuwela umgoqo wegazi nobuchopho. Lokhu kuvuselela ukukhiqizwa kwe-glutamate, i-neurotransmitter ebalulekile ebalulekile ekuhlanganisweni kwe-synaptic, noma ikhono lama-synapses ezinzwa ukuphendula ekwandeni noma ekwehleni komsebenzi. Amazinga e-Glutamate abaluleke kakhulu ku-hippocampus, ingxenye yobuchopho edlala indima ebalulekile ekuzulazuleni kwendawo, ekwakhekeni kwememori, kanye nokugcinwa kwayo. Amazinga e-glutamate anele abalulekile ekuthuthukisweni kwesikhathi eside noma ekuthuthukisweni okuhlala njalo kwezimpawu phakathi kwama-neurons. Amandla abalulekile. Iningi lamandla okuthuthukisa ingqondo e-Sunifilaram ekugcineni lisebenza ngokwandisa amandla ezimpawu ze-neural kule ngxenye yobuchopho.
Isici
(1) Ukuhlanzeka okuphezulu: I-Sunifiram ingathola imikhiqizo ehlanzeka kakhulu ngezinqubo zokukhiqiza ezicwengekile. Ukuhlanzeka okuphezulu kusho ukutholakala okungcono kwe-bioavailability kanye nokusabela okuncane okubi.
(2) Ukuphepha: I-Sunifiram itholakale iphephile emzimbeni womuntu.
(3) Ukuzinza: I-Sunifiram inokuqina okuhle futhi ingagcina umsebenzi wayo kanye nomphumela ngaphansi kwezimo ezahlukene zokugcinwa.
Izicelo
I-Sunifiram iyisithuthukisi se-neuroplasticity, futhi iyatholakala njengesengezo sokudla, okucatshangwa ukuthi ithuthukisa ukusebenza kwengqondo futhi ithuthukise ukufunda kanye nenkumbulo. Isebenza ngokucubungula ama-receptor e-AMPA ebuchosheni. I-AMPA iyi-neurotransmitter ehilelekile ekuxhumaneni okusheshayo phakathi kwamaseli ohlelweni lwezinzwa. Ithuthukisa kakhulu isivinini sokufunda, ukugcinwa kwenkumbulo kanye nokukhumbula, kanye nokuthuthukisa ukugxilisa ingqondo, ukugqugquzeleka kanye nokucaca kwengqondo.
