Ikhono lokucabanga libhekisela ekhonweni lomuntu lokucubungula ulwazi, ukukhumbula, ukufunda, ukuqonda nokuxazulula izinkinga. Kuyisici esibalulekile nesibalulekile ukuthi umuntu aphumelele emsebenzini nasempilweni. Umthelela wendlela yokuthuthukisa ikhono lengqondo unemithelela ebalulekile empumelelweni yomuntu siqu kanye nenhlalakahle.
Kule nkathi yolwazi, kufanele sithole ulwazi oluningi nsuku zonke. Ubuchopho abudingi nje ukuthola ulwazi kuphela, kodwa futhi nokucubungula nokuqopha ulwazi. Ngaphansi komthwalo onjalo womsebenzi onamandla, kuyadingeka ukuthuthukisa ikhono lokucabanga lobuchopho. Ukuthuthukiswa kwengqondo kungasiza abantu ukuba bathuthukise inkumbulo, okwesikhathi esifushane kanye nesikhathi eside. Ukwazi kangcono ukukhumbula nokukhumbula ulwazi, ukuthuthukisa ukufunda nokukhiqiza.
Ngokombono wesayensi, ikhono lengqondo liwumqondo ozinzile, kodwa ucwaningo lubonisa ukuthi abantu bangathuthukisa ikhono labo lokuqonda ngokusebenzisa amasu athile nokuqeqeshwa. Lokhu kubalulekile ngoba kusho ukuthi asilindelekile ukuba sibe nekhono elithile lokucabanga, kodwa ukuthi singalithuthukisa ngenkuthalo ngezenzo eziqaphelayo.
Ngakho, iyini ngempela iPramiracetam? I-Pramiracetam iyinhlanganisela yokwenziwa yomndeni wama-racemates. I-Pramiracetam yasungulwa ngawo-1970 futhi iye yacwaningwa kabanzi ngezakhiwo zayo ezithuthukisa ukuqonda. Kukholakala ukuthi isebenza ngokuvuselela ama-receptors athile ebuchosheni ahlotshaniswa nezinqubo zokufunda nenkumbulo, ngaleyo ndlela ithuthukise ukusebenza kwengqondo okuphelele.
I-Pramiracetam ithuthukisa ukwakheka kwenkumbulo nokubuyiswa. Ucwaningo luye lwabonisa ukuthi Pramiracetamingathuthukisa kakhulu inkumbulo yesikhathi esifushane neyesikhathi eside.Lokhu kuwusizo ikakhulukazi kubafundi nakubantu ngabanye abafuna ukuthuthukisa amakhono abo okuqonda jikelele.
Futhi kuthuthukisa ukugxila nokugxila. Abasebenzisi abaningi babika ukuthi i-Pramiracetam ibasiza ukuthi bahlale beqaphile futhi begxile isikhathi eside, okwenza kube kuhle kubantu abadinga ukugxila kakhulu emsebenzini noma esikoleni.
Kubikwe ukuthi kuthuthukisa ikhono lomuntu lokucabanga ngokucacile, ukucubungula ulwazi ngokushesha, nokwenza ukuxhumana okunengqondo. Le miphumela ingase ifakwe emiphumeleni ye-Pramiracetam kuma-acetylcholine receptors ebuchosheni, i-neurotransmitter edlala indima ebalulekile ezinqubweni zokuqonda.
Funda mayelana nePramiracetam:
I-Pramiracetam iyinhlanganisela yokwenziwa evela emndenini we-racemate owaziwa ngezakhiwo zayo ezithuthukisa ingqondo. Kubhekwa kabanzi njengenye ye-nootropics enamandla kakhulu futhi enamandla, eklanyelwe ukuthuthukisa inkumbulo, ukugxilisa ingqondo, nokusebenza kwengqondo jikelele.
Ukusebenza Nezinzuzo:
Ucwaningo oluningana luye lwahlola ukusebenza kahle kwePramiracetam, luqokomisa izinzuzo zayo ezingase zibe khona zokucabanga. Ucwaningo oluvelele olwanyatheliswa kuyi-Journal of Psychopharmacology lubike ukuthi i-Pramiracetam ithuthukise inkumbulo nokufunda kubantu abanempilo. Abahlanganyeli abaphathwa nge-Pramiracetam babonise ukuthuthukiswa okuphawulekayo emisebenzini yokukhumbula, ukucubungula ukuqonda, nokugcinwa kwenkumbulo yesikhathi eside.
Ukwengeza, i-Pramiracetam kucatshangwa ukuthi ithuthukisa inkumbulo yokusebenza, ebalulekile emisebenzini edinga ukugxilisa ingqondo nokushesha kwengqondo. Ngokugqugquzela ukukhululwa nokuthathwa kwe-acetylcholine, i-neurotransmitter ebalulekile enkumbulo nokufunda, i-Pramiracetam iboniswe ukuthuthukisa ukusebenza kwengqondo kubantu abanokukhubazeka kwenkumbulo.
Ukwengeza, i-Pramiracetam ivame ukuphakanyiswa ngenxa yezakhiwo zayo ze-neuroprotective. Kucatshangwa ukuthi le nootropic ithuthukisa ukusetshenziswa kwe-oksijeni kanye ne-glucose metabolism ebuchosheni, ngaleyo ndlela ithuthukise impilo yobuchopho futhi ivimbele ukwehla kwengqondo.
Indlela:
Indlela eqondile yokusebenza lapho iPramiracetam isebenzisa imiphumela yayo yokuthuthukisa ingqondo ayiqondwa ngokugcwele. Kodwa-ke, kucatshangwa ukuthi ilawula kokubili izinhlelo ze-cholinergic ne-glutamatergic, zombili ezidlala indima ebalulekile ekusebenzeni kwengqondo.
Ukulawulwa kwe-cholinergic kuhilela ukukhululwa kanye nokuthathwa kwe-acetylcholine, i-neurotransmitter ebhekele ukwakheka kwenkumbulo nokuhlanganisa. Ngokwandisa ukutholakala kwe-acetylcholine, i-Pramiracetam kucatshangwa ukuthi ikhulise ukusayina kwe-synaptic, ngaleyo ndlela ikhuthaze ukufunda okuthuthukisiwe nenkumbulo.
Ukulawulwa kwe-glutamate, ngakolunye uhlangothi, kuhlotshaniswa nokulawulwa kwe-neurotransmission ejabulisayo. I-Pramiracetam kucatshangwa ukuthi ithuthukisa ukutholwa kwe-glutamate, okukhuthaza ukuthuthukiswa kwe-synaptic plasticity kanye nokusebenza kwengqondo jikelele.
Emhlabeni wokuthuthukiswa kwengqondo kanye nezidakamizwa ze-nootropic, i-Pramiracetam ne-piracetam yizinto ezimbili ezidumile ezivame ukweba umbukiso. Lezi zinhlanganisela ziyingxenye yezidakamizwa zokwenziwa ezaziwa ngokuthi ama-racemates, aziwa ngemiphumela yawo engase ibe ngcono yokuthuthukisa ingqondo. Kokubili i-Pramiracetam ne-piracetam yizidakamizwa ze-nootropic ezithuthukisa ukusebenza kobuchopho, zithuthukise inkumbulo, zithuthukise ukugxila, futhi zithuthukise ukusebenza kwengqondo okuphelele. Nokho, naphezu kokufana, kunomehluko othize phakathi kwalezi zinto ezimbili.
1. Ukwakheka kwamakhemikhali:
I-Piracetam, eyandulela yazo zonke izidakamizwa ze-racemic, yatholakala ngawo-1960. Iqukethe isakhiwo se-pyrrolidone futhi iyilungu eliyisisekelo lomndeni we-racemate. I-Pramiracetam, ngakolunye uhlangothi, iphuma ku-piracetam eneqembu le-dipropan-2-ylaminoethyl elingezwe esakhiweni sayo. Lolu shintsho oluncane lwenza i-Pramiracetam isebenze kakhulu kune-piracetam.
2. Ukusebenza kahle kanye nomthamo:
Mayelana namandla, i-Pramiracetam iphakeme kune-Piracetam. Ilinganiselwa ukuthi inamandla aphindwe izikhathi eziyishumi kuya kwezingu-30 kunowandulelayo. Ngenxa yamandla ayo athuthukisiwe, imithamo ephansi kakhulu iyadingeka ku-Pramiracetam uma kuqhathaniswa ne-piracetam.
3. Indlela yokwenza:
I-Pramiracetam ne-piracetam zombili zisebenza ngokuthinta uhlelo lwe-cholinergic ebuchosheni. Zithinta ukukhiqizwa nomsebenzi wama-neurotransmitters afana ne-acetylcholine, edlala indima ebalulekile enkumbulo, ekufundeni nakwezinye izinqubo zokuqonda. Kodwa-ke, i-Pramiracetam icatshangwa ukuthi inomphumela oqondile ekuthathweni kwe-choline ephezulu-affinity (HACU) ku-hippocampus, isifunda sobuchopho esibhekene nokwakheka kwenkumbulo nokubuyiswa. Lesi senzo esiyingqayizivele sePramiracetam senza ukuthi iphumelele ikakhulukazi ekuthuthukiseni inkumbulo.
4. Izinzuzo zengqondo:
Kokubili i-Pramiracetam ne-piracetam kunezinzuzo eziningi uma kuziwa ekuthuthukisweni kwengqondo. I-Piracetam ivame ukuthandwa ngenxa yekhono layo lokuthuthukisa inkumbulo, ukugxilisa ingqondo, nokugxila. Kwaziwa futhi ngokuthuthukisa ukusebenza kwengqondo okuphelele, okuyenza ilungele abantu abafuna ukuthuthukisa ukusebenza kwabo kwengqondo kukonke. I-Pramiracetam, ngakolunye uhlangothi, iphumelela ngokukhethekile ekuthuthukiseni inkumbulo yesikhathi eside, ukuthuthukisa ukufunda kwendawo, nokwandisa ukugxila.
5. Imiphumela engemihle engaba khona:
I-Pramiracetam ne-piracetam ngokuvamile ibekezelelwa kahle ngezigameko eziphansi zemiphumela emibi. Nokho, izimpendulo ngazinye zingahluka. Imiphumela emibi evamile engase yenzeke ihlanganisa ikhanda elibuhlungu, izinkinga zesisu, ukwesaba, nesiyezi. Le miphumela ivamise ukuba mnene futhi ibe yesikhashana, iyancipha njengoba umzimba ulungisa into.
Uma kuziwa kumthamo we-pramiracetam, kufanele kugcizelelwe ukuthi amakhemikhali omzimba womuntu ngamunye nokubekezelelana kungase kuhluke. Ngakho-ke, umthamo ungahluka futhi ngokuya ngezidingo nezinjongo zomuntu ngamunye. Ngokuvamile, umthamo wansuku zonke ojwayelekile we-Pramiracetam usukela ku-500 kuya ku-1,200 mg ihlukaniswe ngemithamo emibili noma emithathu usuku lonke.
Kunconywa ukuthi uqale nge-dose ephansi ephumelelayo futhi kancane kancane ukwandisa uma kunesidingo. Futhi hlola impendulo yomzimba wakho. Uma ungekho umphumela obonakalayo obonwayo, umthamo ungalungiswa ukhuphukele ukuvumela isikhathi somzimba wakho ukujwayela ushintsho ngalunye lomthamo.
umphumela ohlangothini:
Nakuba i-Pramiracetam ivame ukubekezelelwa kahle, umuntu kufanele aqaphele imiphumela emibi engase ibe khona. Imiphumela emibi ebikiwe ye-Pramiracetam imnene futhi ayijwayelekile, futhi ngokuvamile ixazulula ngemva kokuyekiswa kwe-compound. Le miphumela engemihle ingase ihlanganise:
●Ubuhlungu bekhanda: Ikhanda elibuhlungu elibuhlungu liwumphumela ovame kakhulu ohambisana nokusetshenziswa kwe-Pramiracetam. Ukwandisa ukungena kwe-choline ngemithombo yokudla efana namaqanda noma ukusebenzisa izithako ze-choline kungasiza ukunciphisa lo mphumela ohlangothini.
●Ukucasuka kwamathumbu: Abanye abasebenzisi babike izimpawu zokugaya ezifana nokucanuzela kwenhliziyo, ukucasuka kwesisu, noma isifo sohudo. Ukuqinisekisa ukuthi uthatha i-Pramiracetam ngokudla kungasiza ekunciphiseni le miphumela.
●Ukuphazamiseka kokulala: I-Pramiracetam ingabangela ukuphazamiseka kokulala njengokuqwasha uma kuthathwa kamuva ngosuku. Ukuze ugweme lokhu, kunconywa ukuthatha i-praracetam ekuqaleni kosuku noma ekuseni.
●Ukukhathazeka noma ukungezwani: Ezimweni ezingavamile, umuntu angase abe nokukhathazeka okwengeziwe noma ukungezwani. Uma uhlangabezana nalezi zimpawu, kutuswa ukuthi uyeke ukusebenzisa futhi uxhumane nochwepheshe bezempilo.
Q: Kuthatha isikhathi esingakanani ukuzwa imiphumela ye-Pramiracetam?
A: Ukuqala kwemiphumela yePramiracetam kungahluka kumuntu nomuntu. Nakuba abanye abantu bangase baqale ukuqaphela izinzuzo zayo emahoreni ambalwa, abanye bangathatha izinsuku ezimbalwa zokusetshenziswa okungaguquki ukuze bathole ukuthuthuka okuphawulekayo ekusebenzeni kwengqondo.
Q: Ingabe i-Pramiracetam iphephile ukusetshenziswa?
A: I-Pramiracetam ngokuvamile ibhekwa njengephephile ukusetshenziswa lapho ithathwa ngesilinganiso esinconywayo. Kodwa-ke, njenganoma yisiphi isithasiselo noma imithi, kuhlale kuhle ukuthi uthintane nochwepheshe bezempilo ngaphambi kokuqala ukuyisebenzisa, ikakhulukazi uma unanoma yiziphi izimo zezokwelapha ezicashile noma uthatha eminye imithi.
Umshwana wokuzihlangula: Lesi sihloko senzelwe izinjongo zokwaziswa kuphela futhi akufanele sithathwe njengeseluleko sezokwelapha. Hlala uthintana nochwepheshe bezempilo ngaphambi kokusebenzisa noma yiziphi izithasiselo noma ukushintsha uhlobo lwakho lokunakekelwa kwezempilo.
Isikhathi sokuthumela: Aug-11-2023
