Iyini i-salidroside futhi ingakusiza kanjani?

I-Salidroside yaziwa nangokuthi (4-hydroxy-phenyl)-β-D-glucopyranoside, eyaziwa nangokuthi i-salidroside kanye ne-rhodiola extract. Ingakhishwa ku-Rhodiola rosea noma yenziwe ngokwenziwa. I-Salidroside iyi-antioxidant yemvelo evikela amangqamuzana ezinzwa ngokukhipha i-ROS futhi ivimbele i-apoptosis yamaseli.

I-Rhodiola rosea isitshalo esihlala isikhathi eside esimila ezindaweni ezibandayo kakhulu, ukoma, i-anoxia, imisebe ye-ultraviolet enamandla, nomehluko omkhulu wokushisa phakathi kwemini nobusuku endaweni ephakeme ngamamitha angu-1,600 kuya ku-4,000. Inokuguquguquka okunamandla kwemvelo kanye nobungqabavu.

I-Salidroside - i-Antioxidant

I-Salidroside iyi-antioxidant yemvelo engabulala izinhlobo ze-oxygen esebenzayo (ROS), ivimbele i-apoptosis, futhi ivikele amaseli ezinzwa. Ingathuthukisa amandla okuzivikela esikhumbeni ngokuvula ama-enzyme e-antioxidant e-intracellular, afana ne-superoxide dismutase (SOD), i-glutathione peroxidase (GSH-Px), njll.

I-Intracellular calcium overload ingenye yezimbangela eziyinhloko ze-neuronal apoptosis. I-Rhodiola rosea ekhishwe kanye ne-salidroside inganciphisa ukwanda kwamazinga e-calcium yamahhala e-intracellular ebangelwa ukucindezeleka kwe-oxidative futhi ivikele amangqamuzana e-cortical yomuntu ku-glutamate. kanye ne-apoptosis eyenziwe nge-hydrogen peroxide. I-Salidroside ingavimbela ukusebenza kwe-microglial eyenziwe nge-lipopolysaccharide, ivimbele ukukhiqizwa kwe-NO, ivimbele umsebenzi we-inducible nitric oxide synthase (iNOS), futhi yehlise i-TNF-α ne-IL-1β. , amazinga we-IL-6.

I-Salidroside ivimbela i-NADPH oxidase 2/ROS/mitogen-activated protein kinase (MAPK) kanye nesilawuli sokuphendula sokuthuthukiswa kanye nokulimala kwe-DNA 1 (REDD1)/ithagethi yezilwane ezincelisayo ye-rapamycin (mTOR)/p70 ribosome Indlela yokusayina ye-protein S6 kinase yenza kusebenze okuncike ku-AMP I-protein kinase/isilawuli solwazi esithulile 1, ilungu lomndeni le-RAS lesakhi sofuzo esifana ne-A/MAPK kanye nezindlela zokusayina ze-PI3K/Akt.

Izinzuzo zeSalidroside

1. Umphumela wokulawula wezindlela ezimbili: I-Rhodiola rosea ihlanganisa zonke izici ezinhle emzimbeni futhi inomphumela wokulawula wezindlela ezimbili wokwenza ukuntula nokunciphisa ngokweqile. Ngokulawula imisebenzi yesistimu yezinzwa, uhlelo lwe-endocrine kanye nesistimu ye-metabolic, ushukela wegazi, i-lipids yegazi, umfutho wegazi kanye nemisebenzi yenhliziyo nemithambo ye-cerebrovascular ingabuyiselwa emazingeni ajwayelekile.

2. Ukulawulwa okuphumelelayo kwesimiso sezinzwa: ukuqeda ngokuphumelelayo ukungezwani kwabantu, ukulinganisela isimiso sezinzwa esiyinhloko, ukuthuthukisa ukulala nokucasuka, ukujabula noma ukucindezeleka; thuthukisa ukunaka futhi uthuthukise inkumbulo. Vuselela ubuchopho, unciphise amazinga amaphutha, uthuthukise ukusebenza kahle nokufunda, futhi uvimbele isifo i-Alzheimer's.

3. Ukulwa nokukhathala: I-Rhodiola rosea inomphumela we-cardiotonic, ongakhuphula ubude besikhathi semisebenzi evamile yobuchopho nomzimba futhi andise umthamo womthwalo wezinzwa zobuchopho nemisipha yomzimba. Kunomthelela omkhulu ekuvimbeleni nasekwelapheni ukukhathala kwe-syndrome nokugcina amandla aqinile nobungqabavu isikhathi eside.

4. I-Anti-radiation kanye ne-anti-tumor: I-Salidroside ingakhuphula ngempumelelo izinga lokuguqulwa kwama-T lymphocyte kanye nomsebenzi wama-phagocyte, ithuthukise amasosha omzimba, ivimbele ukukhula kwesimila, yandise amangqamuzana egazi amhlophe, imelane nemisebe ye-microwave, futhi yelaphe iziguli zomdlavuza ngemva kokwelashwa ngemisebe kanye nokunye. Inomphumela omuhle kakhulu wokuvuselela osizayo kulabo ababuthakathaka ngokomzimba ngemva kokugula.

5. I-Anti-hypoxia: I-Rhodiola rosea inganciphisa izinga lokusebenzisa komoya-mpilo lilonke, ithuthukise ukubekezelela ubuchopho ku-hypoxia, futhi ngesikhathi esifanayo yandise amandla egazi okuthwala umoya-mpilo, yandise ukumelana nezifo zomzimba, futhi ilulame ngokushesha izicubu ezigulayo. .

6. Umthelela esicupheni somuntu esibushelelezi: Isifuba somoya sibangelwa ukugogeka kwemisipha ebushelelezi. I-Rhodiola rosea ingadambisa ngempumelelo imisipha ebushelelezi futhi ilawule ukunyakaza kwemisipha yamathumbu. Inemiphumela esobala ku-asthma, i-bronchitis, i-phlegm, ukuqunjelwa, njll.

7. Umthelela ku-rheumatoid arthritis: Isifo samathambo sibangelwa ububi obuthathu bomoya, amakhaza, nokuba manzi. Inombolo enkulu yokuhlolwa komtholampilo kufakazele ukuthi i-Rhodiola rosea ingaxosha umoya, imelane nokubanda, futhi iqede ubuhlungu. Ikakhulukazi inemiphumela esobala ekuvuvukeni kwamalunga. Ukuvuvukala nomphumela ovimbelayo.

8. Ukulwa nokuguga: I-Rhodiola rosea ingabambezela ukuguga kwamangqamuzana, ikhulise umsebenzi we-SOD emzimbeni, futhi ivimbele ukwakheka kwe-intracellular lipofuscin kanye nezinhlobo ze-oxygen esebenzayo. Thuthukisa i-metabolism yamangqamuzana futhi uhlanganise futhi uthuthukise ubungqabavu beseli. Ngaphezu kwalokho, ibuye ibe nemiphumela yobuhle nokunakekelwa kwesikhumba.

I-Salidroside & Skin Care Field

Emkhakheni wokunakekelwa kwesikhumba, i-salidroside ingamelana nokulimala kwe-ultraviolet futhi isuse ama-radicals mahhala akhiqizwa yi-mitochondria. Imiphumela yayo ye-antioxidant ne-anti-inflammatory ingathuthukisa isimo sesikhumba, inciphise imibimbi, futhi yenze isikhumba sibukeke sisincane.

I-Rhodiola rosea inganciphisa umsebenzi we-asidi phosphatase kanye nemikhiqizo yokugcina yokubola ye-lipid peroxide (LPO) ngokwandisa umsebenzi wama-enzyme ahlobene ne-antioxidant (SOD superoxide dismutase, GSH-Px glutathione peroxidase kanye ne-CAT) okuqukethwe nokuqukethwe kwe-MDA, ngaleyo ndlela kuthuthukise ikhono lomzimba. ukuqothula ama-radicals mahhala, ukunciphisa izinga le-peroxidation ye-biofilms, nokuvikela amangqamuzana omzimba nezicubu emonakalweni wamahhala.

Vimbela ukuthwebula kwesikhumba

I-Salidroside inganciphisa ukuwohloka kwe-matrix engaphandle kwe-extracellular njenge-collagen futhi ikhuthaze ukukhula kwama-fibroblasts, ngaleyo ndlela ithuthukise ukunwebeka kwesikhumba, ibambezeleke ukuvela kwemibimbi yesikhumba, futhi ifinyelele inhloso yokumelana ne-photoaging.

Ukuba mhlophe

I-Salidroside inganciphisa ukwakheka kwe-melanin ngokuvimbela umsebenzi we-tyrosinase. I-Tyrosinase iyi-enzyme eyinhloko ye-melanin synthesis. I-Salidroside ingabopha ku-tyrosinase futhi inciphise umsebenzi wayo, ngaleyo ndlela inciphise ukukhiqizwa kwe-melanin.

I-Salidroside ingaphinda ivimbele ukwakheka kwe-melanin ngokulawula izindlela zokubonisa kuma-melanocyte, njengendlela yokusayina ye-MITF. I-MITF iyisici esibalulekile sokuloba kuma-melanocyte, alawula ukuvezwa kwama-enzyme ahlobene ne-melanin synthesis njenge-tyrosinase. I-Salidroside inganciphisa ukubonakaliswa kwe-MITF, ngaleyo ndlela yehlise ukwakheka kwe-melanin.

I-anti-inflammatory

I-Salidroside inganciphisa ukusabela kokuvuvukala okubangelwa imisebe ye-ultraviolet, ilungise amangqamuzana esikhumba awonakele, futhi ikhuthaze ukuvuselelwa nokulungiswa kwesikhumba.

Isimo samanje sokukhiqizwa kwe-salidroside

1)Thembela kakhulu ekukhishweni kwezitshalo

I-Rhodiola rosea iyimpahla eluhlaza ye-salidroside. Njengohlobo lwesitshalo se-herbaceous perennial, i-Rhodiola rosea ikhula ikakhulukazi ezindaweni ezibandayo kakhulu, i-anoxia, ukoma kanye nomehluko omkhulu wokushisa phakathi kwemini nobusuku endaweni engamamitha ayi-1600-4000. Ingesinye sezitshalo zasemathafeni asendle. I-China ingenye yezindawo ezikhiqiza kakhulu i-Rhodiola rosea emhlabeni, kodwa imikhuba yokuphila ye-Rhodiola rosea ikhethekile kakhulu. Akukhona nje kuphela ukuthi kunzima ukuhlakulela ngokwenziwa, kodwa isivuno sezinhlobo zasendle siphansi kakhulu. Njengamanje, igebe lonyaka lokufunwa kwe-Rhodiola rosea liphezulu njengoba lifinyelela kumathani ayi-2,200.

2) Ukuhlanganiswa kwamakhemikhali kanye nokuvutshelwa kwezinto eziphilayo

Ngenxa yokuqukethwe okuphansi kanye nezindleko eziphezulu zokukhiqiza ezitshalweni, ngaphezu kwezindlela zokukhipha imvelo, izindlela zokukhiqiza i-salidroside zihlanganisa izindlela zokuhlanganisa amakhemikhali, izindlela zokuvutshelwa kwezinto eziphilayo, njll. Phakathi kwazo, njengoba ubuchwepheshe buqhubeka buvuthwa, ukuvutshelwa kwezinto eziphilayo kuye kwaba okujwayelekile. indlela yobuchwepheshe yocwaningo nokuthuthukiswa kanye nokukhiqizwa kwe-salidroside. Njengamanje, i-Suzhou Mailun isizuze imiphumela yocwaningo nentuthuko futhi isizuze ukuthuthukiswa kwezimboni.

Imisebe iyingxenye engenakugwenywa yokuphila kwethu kwansuku zonke futhi isetshenziswa kaningi ekuxilongeni nasekwelashweni. Nokho, umonakalo obangelwa imisebe ezicutshini zomuntu namangqamuzana awunakuzitshwa. Ngakho-ke, ukuthola ama-ejenti avikelayo emisebe asebenzayo, anobuthi obuphansi noma angenabo ubuthi bekuhlale kuyisizinda socwaningo.

I-Suzhou Myland Nutraceuticals Inc. ingumkhiqizi obhalisiwe we-FDA ohlinzeka ngempushana ye-Salidroside yekhwalithi ephezulu nehlanzekile.

KwaSuzhou Myland sizibophezele ekuhlinzekeni ngemikhiqizo esezingeni eliphezulu ngamanani angcono kakhulu. I-Salidroside powder yethu ihlolwe ngokuqinile ukuhlanzeka namandla, iqinisekisa ukuthi uthola isengezo sekhwalithi ephezulu ongasethemba. Kungakhathaliseki ukuthi ufuna ukusekela impilo yeselula, ukuqinisa amasosha akho omzimba noma ukuthuthukisa impilo yonke, i-Salidroside powder yethu iyisinqumo esihle kakhulu.

Njengoba inesipiliyoni seminyaka engu-30 futhi iqhutshwa ubuchwepheshe obuphezulu kanye namasu e-R&D athuthukiswe kakhulu, i-Suzhou Myland isungule uhide lwemikhiqizo encintisanayo futhi yaba isithasiselo sesayensi yempilo emisha, ukuhlanganisa ngokwezifiso kanye nenkampani yezinkonzo zokukhiqiza.

Ngaphezu kwalokho, iSuzhou Myland iphinde ibe ngumkhiqizi obhalisiwe we-FDA. Izinsiza ze-R&D zenkampani, izikhungo zokukhiqiza, namathuluzi okuhlaziya kungokwesimanjemanje futhi kunemisebenzi eminingi, futhi ingakhiqiza amakhemikhali ukusuka kumamiligremu ukuya kumathani esikalini, futhi ihambisane namazinga e-ISO 9001 kanye nemininingwane yokukhiqiza ye-GMP.