Uyini umehluko phakathi kwe-spermidine trihydrochloride ne-spermidine? Akhishwa kuphi?

I-Spermidine trihydrochloridekanye ne-spermidine yizinhlanganisela ezimbili ezihlobene okuthi, nakuba zifana ngesakhiwo, zibe nomehluko endaweni yazo, ukusetshenziswa, kanye nemithombo yokukhipha.

I-Spermidine iyi-polyamine eyenzeka ngokwemvelo etholakala kakhulu ezintweni eziphilayo, ikakhulukazi edlala indima ebalulekile ekwandeni kwamangqamuzana nokukhula. Isakhiwo sayo samangqamuzana siqukethe amaqembu amaningi e-amino nama-imino futhi inomsebenzi oqinile webhayoloji. Izinguquko zokuhlushwa kwe-spermidine emangqamuzaneni zihlobene eduze nezinqubo ezihlukahlukene zomzimba, kuhlanganise nokwanda kwamaseli, ukuhlukaniswa, i-apoptosis kanye ne-anti-oxidation. Imithombo eyinhloko ye-spermidine ihlanganisa izitshalo, izilwane kanye nama-microorganisms, ikakhulukazi ekudleni okuvutshiwe, ubhontshisi, amantongomane kanye nemifino ethile.

I-Spermidine trihydrochloride iwuhlobo lukasawoti lwe-spermidine, ngokuvamile olutholakala ngokusabela i-spermidine nge-hydrochloric acid. Uma kuqhathaniswa ne-spermidine, i-spermidine trihydrochloride inokuncibilika okuphezulu emanzini, okwenza kube nenzuzo kakhulu kwezinye izinhlelo zokusebenza. I-Spermidine trihydrochloride ivamise ukusetshenziswa ocwaningweni lwebhayoloji nasembonini yezemithi njengesengezo kusiko lamaseli nokuhlolwa kwebhayoloji. Ngenxa yokuncibilika kwayo okuhle, i-spermidine trihydrochloride isetshenziswa kakhulu emithonjeni yezokuxhumana yamaseli ukukhuthaza ukukhula nokwanda kwamaseli.

Ngokuphathelene nokukhipha, i-spermidine ivame ukutholwa ngokukhipha emithonjeni yemvelo, njengokukhipha izingxenye ze-polyamine ezitshalweni. Izindlela ezivamile zokukhipha zihlanganisa ukukhishwa kwamanzi, ukukhipha utshwala kanye nokukhishwa kwe-ultrasonic. Lezi zindlela zingahlukanisa ngempumelelo i-spermidine ezintweni ezingavuthiwe futhi zizihlanze.

Ukukhishwa kwe-spermidine trihydrochloride kulula futhi kuvame ukutholwa ngokuhlanganiswa kwamakhemikhali ngaphansi kwezimo zaselabhorethri. I-Spermidine trihydrochloride ingatholakala ngokuphendula i-spermidine nge-hydrochloric acid. Le ndlela yokuhlanganisa ayiqinisekisi kuphela ukuhlanzeka komkhiqizo, kodwa futhi ivumela ukugxila kwayo kanye nefomula ukuthi ilungiswe njengoba kudingeka.

Mayelana nesicelo, kokubili i-spermidine ne-spermidine trihydrochloride zisetshenziswa kabanzi ocwaningweni lwe-biomedical. I-Spermidine ivame ukungezwa emikhiqizweni yezempilo kanye nezithako zokudla okunomsoco ukusiza ukuthuthukisa ukusebenza kwamangqamuzana nokunciphisa inqubo yokuguga ngenxa yendima yayo ekwandeni kwamangqamuzana nokulwa nokuguga. I-Spermidine trihydrochloride ivame ukusetshenziswa kusiko lamaseli kanye nokuhlolwa kwebhayoloji njengomgqugquzeli wokukhula kwamaseli ngenxa yokuncibilika kwayo okuhle kakhulu.

Ngokuvamile, kunomehluko othile phakathi kwe-spermidine ne-spermidine trihydrochloride ngesakhiwo nezakhiwo. I-Spermidine iyi-polyamine eyenzeka ngokwemvelo, ikakhulukazi ekhishwe ezitshalweni nasezicutshini zezilwane, kuyilapho i-spermidine trihydrochloride iwuhlobo lwayo lukasawoti, ngokuvamile olutholakala ngokusebenzisa ukuhlanganiswa kwamakhemikhali. Zombili zinenani elibalulekile ocwaningweni lwe-biomedical nasekusetshenzisweni. Ngokujula kocwaningo lwesayensi, imikhakha yezicelo zabo izoqhubeka nokukhula, inikeze amathuba amaningi ocwaningo lwezempilo nolwezokwelapha.