I-Galantamine Hydrobromide powder umkhiqizi we-CAS No.: 1953-04-4 98% ubumsulwa min. okwengeza izithako
Amapharamitha womkhiqizo
| Igama lomkhiqizo | I-Galantamine Hydrobromide |
| Elinye igama | I-Galanthamine hydrobromide; I-Galantamine HBr; I-Galanthamine HBr;(4aS,6R,8aS)-4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-Benzofuro[3a,3,2-ef][2]benzazepin- 6-ol, Hydrobromide |
| Inombolo ye-CAS. | 1953-04-4 |
| Ifomula yamangqamuzana | I-C17H21NO3.HBr |
| Isisindo samangqamuzana | 368.27 |
| Ubumsulwa | 98.0% |
| Ukubukeka | impushana emhlophe ukuya emhlophe |
| Ukupakisha | 1kg/isikhwama 10kgs,25kgs/drum |
| Isicelo | izidakamizwa ze-nootropic |
Isingeniso somkhiqizo
I-Galantamine hydrobromide iyi-benzazepine etholakala kuma-bulb nezimbali ze-narcissus, i-osmanthus, noma i-canna. Futhi iyi-oral cholinesterase inhibitor. Njenge-ligand ye-nicotinic acetylcholine receptors, iye yasetshenziswa kabanzi ukuthuthukisa umsebenzi we-neurocognitive. Umsebenzi wayo ukuvimbela ngokuncintisana nangokuhlehla i-acetylcholinesterase, ngaleyo ndlela kwandise ukugcwala kwe-acetylcholine. Lapho ingena egazini, i-galantamine hydrobromide ingena kalula ezingxenyeni ezihlukahlukene zomzimba, kuhlanganise nobuchopho. Ibophezela kuma-nicotinic acetylcholine receptors, okwenza izinguquko ezihambisanayo nokwandisa ukukhululwa kwe-acetylcholine. Isebenza futhi ngokuncintisana kanye nokubuyisela emuva imiphumela ye-cholinesterase inhibitors. Ngokuvimbela i-cholinesterase, ivimbela ukuwohloka kwe-acetylcholine, ngaleyo ndlela ikhulise amazinga kanye nobude be-neurotransmitter enamandla. I-Galantamine ingase futhi ithuthukise ukufunda nenkumbulo, ivimbele ukuvuvukala kobuchopho, futhi igcine amazinga aphezulu ama-neurotransmitters ngokugcina ubuqotho bama-neurons nama-synapses.
Isici
(1) Ukuhlanzeka okuphezulu: I-Galantamine hydrobromide ingaba umkhiqizo ohlanzekile ngokusebenzisa izinqubo zokukhiqiza zokucwenga. Ukuhlanzeka okuphezulu kusho i-bioavailability engcono kanye nokusabela okungekuhle okumbalwa.
(2) Ukuphepha: I-Galantamine hydrobromide ifakazelwe ukuthi iphephile emzimbeni womuntu.
(3) Ukuzinza: I-Galantamine hydrobromide inokuzinza okuhle futhi ingagcina umsebenzi wayo nomthelela ngaphansi kwezimo ezihlukene nezimo zokugcina.
Izinhlelo zokusebenza
Njengesengezo sokudla, i-galantamine hydrobromide ingathuthukisa inkumbulo, ukwazi, kanye nekhono lokwenza imisebenzi yansuku zonke. Isebenza ngokubuyisela ibhalansi yezinto ezithile zemvelo (ama-neurotransmitters) ebuchosheni, okwandisa isivinini sokwakheka kwenkumbulo futhi kuthuthukise ukugcinwa kwemininingwane namaqiniso. Ngaphezu kwalokho, i-galantamine hydrobromide ithinta ngokuqondile noma ngokungaqondile i-neuroplasticity. Ivuselela i-synaptic plasticity ngokwenza kusebenze i-microglia nama-astrocyte. I-Galantamine inikeza ukuvikelwa kwe-antioxidant ekucindezelekeni kwe-oxidative okubangelwa ama-radicals mahhala.
