Umkhiqizi wempuphu yeGalantamine Hydrobromide Inombolo ye-CAS: 1953-04-4 Ubumsulwa obungu-98% obuncane bezithako ezengeziwe
Amapharamitha Omkhiqizo
| Igama lomkhiqizo | I-Galantamine Hydrobromide |
| Elinye igama | i-Galanthamine hydrobromide; I-Galantamine HBr; I-Galanthamine HBr;(4aS,6R,8aS)-4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, Hydrobromide |
| Inombolo ye-CAS | 1953-04-4 |
| Ifomula yama-molecule | C17H21NO3.HBr |
| Isisindo sama-molecule | 368.27 |
| Ubumsulwa | 98.0% |
| Ukubukeka | impuphu emhlophe kuya kwemhlophe kakhulu |
| Ukupakisha | 1kg/isikhwama 10kgs ,25kgs/isigubhu |
| Isicelo | izidakamizwa ze-nootropic |
Isingeniso somkhiqizo
I-Galantamine hydrobromide iyi-benzazepine etholakala kuma-bulb nezimbali ze-narcissus, i-osmanthus, noma i-canna. Futhi iyisithiyo se-cholinesterase somlomo. Njenge-ligand yama-receptor e-nicotinic acetylcholine, isetshenziswe kabanzi ukuthuthukisa umsebenzi we-neurocognitive. Umsebenzi wayo ukuvimbela i-acetylcholinesterase ngokuncintisana nangokuguqukayo, ngaleyo ndlela kwandiswe ukuhlushwa kwe-acetylcholine. Uma imuncwa egazini, i-galantamine hydrobromide imuncwa kalula ezingxenyeni ezahlukene zomzimba, okuhlanganisa nobuchopho. Ibopha kuma-receptor e-nicotinic acetylcholine, ibangele izinguquko zokwakheka futhi ikhulise ukukhishwa kwe-acetylcholine. Isebenza futhi ngokuncintisana nokuguqula imiphumela yama-inhibitors e-cholinesterase. Ngokuvimbela i-cholinesterase, ivimbela ukuwohloka kwe-acetylcholine, ngaleyo ndlela yandise amazinga kanye nobude balesi sithuthukisi esinamandla. I-Galantamine ingathuthukisa nokufunda kanye nenkumbulo, ivimbele ukuvuvukala kobuchopho, futhi igcine amazinga aphezulu ama-neurotransmitter ngokugcina ubuqotho bama-neurons nama-synapses.
Isici
(1) Ubumsulwa obuphezulu: I-Galantamine hydrobromide ingaba umkhiqizo ohlanzekile kakhulu ngezinqubo zokukhiqiza zokucwenga. Ubumsulwa obuphezulu busho ukutholakala okungcono kwe-bioavailability kanye nokusabela okuncane okubi.
(2) Ukuphepha: I-Galantamine hydrobromide ifakazelwe ukuthi iphephile emzimbeni womuntu.
(3) Ukuzinza: I-Galantamine hydrobromide inokuqina okuhle futhi ingagcina umsebenzi wayo kanye nomphumela ngaphansi kwezimo ezahlukene zokugcinwa.
Izicelo
Njengesengezo sokudla, i-galantamine hydrobromide ingathuthukisa inkumbulo, ukuqonda, kanye nekhono lokwenza imisebenzi yansuku zonke. Isebenza ngokubuyisela ibhalansi yezinto ezithile zemvelo (ama-neurotransmitters) ebuchosheni, okwandisa isivinini sokwakheka kwenkumbulo futhi kuthuthukise ukugcinwa kwemininingwane namaqiniso. Ngaphezu kwalokho, i-galantamine hydrobromide ithinta ngqo noma ngokungaqondile i-neuroplasticity. Ivuselela i-synaptic plasticity ngokusebenzisa i-microglia kanye ne-astrocytes. I-Galantamine inikeza isivikelo se-antioxidant ekucindezelekeni kwe-oxidative okubangelwa ama-free radicals.
