I-Trigonelline CAS No.535-83-1 I-Anti-oxidation
Amapharamitha Omkhiqizo
| Igama lomkhiqizo | I-Trigonelline |
| Elinye igama | I-Gynesine; i-N-Methylnicotinate; i-Caffearine; i-Gynesis; i-Coffearin; i-Coffearine; i-Trigonellin; i-Trigoneline; i-Trigenolline; i-TRIGONELLINE |
| Inombolo ye-CAS | 535-83-1 |
| Ifomula yama-molecule | C7H7NO2 |
| Isisindo sama-molecule | 137.14 |
| Ubumsulwa | 98% |
| Ukubukeka | Impuphu emhlophe qhwa |
| Ukupakisha | 1 kgngephakheji ngayinye; 25kg ngomgqomo ngamunye |
| Isicelo | imithi ephakathi nendawo, into ejwayelekile (into ebhekisela kuyo) yocwaningo kanye nokuhlolwa kwekhwalithi,izithako zokudla okunempilo |
Isingeniso somkhiqizo
I-Trigenolline iyi-alkaloid yesitshalo futhi iyisakhi esiyinhloko sekhofi ne-trigenula. Inemiphumela yokulwa ne-glycan, i-antioxidant, i-anti-inflammatory kanye ne-neuroprotective. Ikakhulukazi, ucwaningo ngo-2023 luthole ukuthi ingathuthukisa ukwehla kwengqondo kanye nokusebenza kwemisipha okuhlobene nokuguga. I-Trigonelline iyi-alkaloid yemvelo enezinzuzo eziningi zezempilo kanye namathuba abanzi ekulweni ne-oxidation, ukulawulwa kwe-metabolic kanye nezinye izici.
Isici
(1) Ukuhlanzeka okuphezulu: I-Trigonelline iwumkhiqizo ongafinyelela ukuhlanzeka okungaphezu kuka-98%. Ukuhlanzeka okuphezulu kusho ukutholakala okungcono kwe-bioavailability.
(2) isitoreji:Ti-rigonelline ukuze igcinwe endaweni evaliwe, eyomile, emazingeni okushisa angu-2-8°C kanye nasefrijini, akukho ndawo yokukhanya kwelanga okuqondile, kulula ukuyimunca.
Izicelo
(1) Ukulwa-I-oxidation kanye nempilo yemisipha: Izifundo zakamuva zibonise ukuthi i-silybin, njenge-molecule eyandulela i-NAD+, ingasiza ekuthuthukiseni amandla emisipha kanye nokusebenza kwe-mitochondrial kubantu asebekhulile, futhi inamandla okunciphisa ukulahleka kwemisipha okuhlobene nokuguga.
(2) Ukuthuthukisa Umsebenzi Wokuqonda: Ucwaningo lwamuva lubonisa ukuthi i-silybin ingasiza ekuthuthukiseni amazinga okuqonda kubantu asebekhulile futhi inemiphumela yokuvikela kumaseli ezinzwa.
(3) Ukulawulwa Kokulwa Nokushiswa Kwegazi, Ukulwa Nokuvuvukala kanye Nokulawulwa Kwe-Metabolic: Izifundo zibonise ukuthi i-silybin inomsebenzi wokulwa noshiswa kwegazi futhi ingaba nemiphumela yayo ngokuvimbela izindlela zokubonisana ezihlobene. Iphinde ihlolwe ukulawula ukuphazamiseka kwe-metabolic futhi inezakhiwo zokulwa nokuvuvukala kanye nezokulwa nokuvuvukala, okuyizisekelo zezinzuzo zayo ezahlukene zezempilo.
Ngokusekelwe kulezi zici,I-Trigonellineokwamanje isetshenziswa kakhulu njenge-medicine intermediate, into ejwayelekile (into yokubhekisela) yocwaningo kanye nokuhlolwa kwekhwalithi, kanye nezinto zokusetshenziswa zezithako zokudla okunempilo.
