I-CMS121 umkhiqizi we-powder CAS No.: 1353224-53-9 98.0% ubumsulwa min. okwengeza izithako
Amapharamitha womkhiqizo
| Igama lomkhiqizo | I-CMS121 |
| Elinye igama | I-CMS-121; 1,2-Benzenediol,4--[4-(cyclopentyloxy)-2-quinolinyl]-; 4-(4-(cyclopentyloxy)quinolin-2-yl)benzene-1,2-diol(CMS121); ACC,AcetylCoenzymeACarboxylase,isifo,neuroprotective,inhibit,anti-inflammatory,mitochondrial,Alzheimer's,antioxidative,acetylation,Inhibitor,H3K9,Acetyl-CoACarboxylase,CMS121,ukuwohloka komqondo,ACC1,CMS-121 |
| Inombolo ye-CAS. | 1353224-53-9 |
| Ifomula yamangqamuzana | I-C20H19NO3 |
| Isisindo samangqamuzana | 321.37 |
| Ubumsulwa | 98.0% |
| Ukubukeka | Impushana ephuzi ekhanyayo |
| Isicelo | I-Dietary Supplement Raw Material |
Isingeniso somkhiqizo
I-4-(4-(cyclopentyloxy)quinolin-2-yl)benzene-1,2-diol iyinhlanganisela futhi ebizwa nge-CMS121. Ubunkimbinkimbi besakhiwo sekhompiyutha buphakamisa ukuthi ingaba nezakhiwo ezihlukile kanye nokusetshenziswa okungenzeka. Ukuze uqonde ukubaluleka kwayo, kusiza ukuhlonza amaqembu asebenzayo akhona futhi ahlaziye umthelela wawo ongaba khona. Ukuba khona kweringi ye-quinoline kusikisela ukuthi inhlanganisela kungenzeka isebenze ngokwebhayoloji. Ama-molecule atholakala ku-quinoline aziwa ngezakhiwo zawo ezihlukahlukene zebhayoloji, okuhlanganisa imisebenzi elwa namagciwane kanye ne-anti-inflammatory. Okunamathiselwe kweqembu le-cyclopentyloxy kungase kube nomthelela ekuncibilikeni kwenhlanganisela noma kuthuthukise umsebenzi wayo webhayoloji ngemiphumela ebulalayo. Ezifundweni zamaseli e-HT22, i-CMS-121 ibonise imiphumela ebalulekile ye-neuroprotective, ivikela ngempumelelo lawa maseli ekulimaleni kwe-ischemia kanye ne-oxidative. Ngaphezu kwalokho, i-CMS-121 inezici ezibalulekile zokulwa nokuvuvukala, okubonisa amandla ayo okulungisa izimpendulo zokuvuvukala. Ngokwenza kanjalo, i-CMS-121 inamandla okunciphisa ukuvuvukala kwezicubu nezitho ezihlukahlukene. I-CMS-121 inomsebenzi oqinile wezokwelapha njengesivimbeli se-acetyl-CoA carboxylase 1 (ACC1). Umphumela wayo onamandla wokuvimbela ku-ACC1 uwenza inhlanganisela ethembisayo.
Isici
(1) Ukuhlanzeka okuphezulu: I-CMS-121 ingathola imikhiqizo ehlanzekile ngezinqubo zokukhiqiza ezicolisisiwe. Ukuhlanzeka okuphezulu kusho i-bioavailability engcono kanye nokusabela okungekuhle okumbalwa.
(2) Ukuphepha: Ukuphepha okuphezulu, ukusabela okumbalwa okungekuhle.
(3) Ukuzinza: I-CMS-121 inokuzinza okuhle futhi ingagcina umsebenzi wayo nomthelela ngaphansi kwezindawo ezihlukene nezimo zokugcina.
Izinhlelo zokusebenza
I-CMS-121 iwumphumela we-quinolone futhi iyasebenza ngomlomo i-acetyl-CoA carboxylase 1 (ACC1) inhibitor enezinto ezethembisayo zemithi. Ucwaningo olunzulu lwenziwe ukuze kuphenywe izinzuzo ezingaba khona ze-CMS-121 ezindaweni ezihlukahlukene, okuhlanganisa i-neuroprotection, imiphumela elwa nokuvuvukala, umsebenzi we-antioxidant, kanye nomthelela wayo kumakaki ahambisana nokuguga okunempilo.
