I-Beta-Nicotinamide Adenine Dinucleotide (NAD +) umkhiqizi we-powder CAS No.: 53-84-9 98.5% ubumsulwa min. okwengeza izithako
Amapharamitha womkhiqizo
Igama lomkhiqizo | I-Nicotinamide Mononucleotide |
Elinye igama | I-NICOTINAMIDE RIBOTIDE; I-BETA-Nicotinamide Mononucleotide; I-NicotinaMide Ribonucleotide; I-β-Nicotinamide Mononucleotide () |
Inombolo ye-CAS. | 1094-61-7 |
Ifomula yamangqamuzana | I-C11H15N2O8P |
Isisindo samangqamuzana | 334.22 |
Ubumsulwa | 98.0% |
Ukubukeka | Impushana emhlophe |
Ukupakisha | 1kg/isikhwama 10kg/isigubhu |
Isicelo | Anti-Ukuguga |
Isingeniso somkhiqizo
I-Beta-Nicotinamide Adenine Dinucleotide (Beta-NAD+), ngokuvamile eyaziwa ngokuthi i-Beta-NAD, iyingqamuzana ebalulekile etholakala kuwo wonke amangqamuzana aphilayo. Idlala indima ebalulekile ezinqubweni ezihlukahlukene zebhayoloji, okuhlanganisa amandla e-metabolism kanye nokusayina kwamaseli. I-Beta-Nicotinamide Adenine Dinucleotide ihlanganiswa kusuka ku-niacin (uvithamini B3) kanye ne-ATP (i-adenosine triphosphate) ngochungechunge lokusabela kwe-enzymatic. Ngesikhathi sokuphefumula kwamaselula, i-Beta-Nicotinamide Adenine Dinucleotide iyi-coenzyme eyenza kube lula ukudluliswa kwama-electron ngesikhathi sokuwohloka kwe-glucose namanye ama-biomolecules. Lokhu kudluliswa kwama-electron kubalulekile ekukhiqizeni i-ATP, imali yeseli yamandla omhlaba wonke. Ngaphandle kwe-Beta-Nicotinamide Adenine Dinucleotide, amaseli awakwazi ukukhiqiza amandla ngokuphumelelayo futhi enze imisebenzi yawo ebalulekile. Ngaphezu kwendima yayo ekusetshenzisweni kwamandla, i-Beta-Nicotinamide Adenine Dinucleotide isebenza njenge-substrate yama-enzyme ahlukahlukene ahilelekile ekuboniseni amangqamuzana nokulawula. Iqembu elilodwa elaziwayo lama-enzyme asebenzisa i-Beta-Nicotinamide Adenine Dinucleotide ama-Sirtuins, abandakanyeka ezinqubweni ezihlukahlukene zamaselula, okuhlanganisa ukulungiswa kwe-DNA, ukubonakaliswa kofuzo, nokuguga. Lawa ma-enzyme adinga i-Beta-Nicotinamide Adenine Dinucleotide njenge-cofactor ukuze enze umsebenzi wawo we-enzymatic.
Isici
(1) Ukuhlanzeka okuphezulu: I-NAD+ ingathola imikhiqizo ehlanzekile ngezinqubo zokukhiqiza zokucwenga. Ukuhlanzeka okuphezulu kusho i-bioavailability engcono kanye nokusabela okungekuhle okumbalwa.
(2) Ukuphepha: Ukuphepha okuphezulu, ukusabela okumbalwa okungekuhle.
(3) Ukuzinza: I-NAD+ inokuzinza okuhle futhi ingagcina umsebenzi wayo nomthelela ngaphansi kwezindawo ezihlukene nezimo zokugcina.
Izinhlelo zokusebenza
I-NAD+ iyi-coenzyme edlala indima ebalulekile ezinqubweni ezihlukahlukene zebhayoloji, okuhlanganisa amandla e-metabolism, ukulungiswa kwe-DNA, nokusayina kwamaseli. I-NAD+ iphinde ibandakanyeke kwezinye izinqubo zamaselula ezifana nokulungiswa kwe-DNA, ukubonakaliswa kofuzo, nokusayina kwe-calcium. Kubalulekile ukugcina ukuguga okunempilo, njengoba amazinga e-NAD+ ehla ngokukhula, okuholela ekwehleni kwemetabolism yamangqamuzana kanye nokwanda kokulimala kwamaseli. Amazinga e-NAD+ ehla ngokuya ngeminyaka, futhi lokhu kuncipha kuhlotshaniswa nezifo ezihlobene nobudala. Ukwengeza ngama-precursors e-NAD+ kukhonjisiwe ukwandisa amazinga e-NAD+ futhi kube nemiphumela engaba khona yokuguga enempilo.