I-PRL-8-53 umkhiqizi we-powder CAS No.: 51352-87-5 98% ubumsulwa min. okwengeza izithako
Amapharamitha womkhiqizo
| Igama lomkhiqizo | I-PRL-8-53 |
| Elinye igama | I-Methyl 3-(2-(benzyl(Methyl)aMino)ethyl)benzoate hydrochloride;i-Benzoic acid, 3-[2--[methyl(phenylmethyl)amino]ethyl]-, i-methyl ester, i-hydrochloride (1:1);I-Methyl 3- {2- [benzyl(methyl)amino]ethyl}benzoate hydrochloride (1:1) |
| Inombolo ye-CAS. | 51352-87-5 |
| Ifomula yamangqamuzana | C18H22ClNO2 |
| Isisindo samangqamuzana | 319.83 |
| Ubumsulwa | 98.0% |
| Ukubukeka | Impushana emhlophe |
| Ukupakisha | 1 kg isikhwama ngasinye 25kg / isigubhu |
| Isicelo | i-nootropic |
Isingeniso somkhiqizo
I-PRL-8-53, eyaziwa nangokuthi i-methyl 3-(2-(benzyl(methyl)amino) ethyl) benzoate, iyinhlanganisela yokwenziwa ye-nootropic ecatshangelwayo yokuthuthukisa ukudluliswa kwe-cholinergic futhi Ilawula amazinga e-dopamine ebuchosheni. Lezi zindlela zokuziphatha zifaka isandla emiphumeleni yayo engase ibe ngcono yokuthuthukisa ingqondo, ngaleyo ndlela ithuthukise ukwakheka kwenkumbulo, ukugcinwa, nokubuyisa. Ucwaningo oluningi ezilwaneni nakubantu lubike imiphumela emihle ngezakhiwo zalo ezithuthukisa inkumbulo. Ocwaningweni lomshayeli oluyimpumputhe kabili, olulawulwa yi-placebo, izihloko ezithole umthamo owodwa we-PRL-8-53 zibonise inkumbulo yamagama engcono kanye namakhono okubuyisa uma kuqhathaniswa neqembu le-placebo. Lokhu okutholakele kwavusa isithakazelo kanye nocwaningo olwengeziwe mayelana namandla enhlanganisela. Olunye ucwaningo lwamagundane lubonise ukuthi ukunikeza i-PRL-8-53 kuthuthukisa kakhulu ikhono labo lokufunda emsebenzini we-maze yamanzi. Amagundane aphathwe nge-PRL-8-53 akwazile ukuthola inkundla efihlekile kahle kakhulu kunezilawuli, ekhombisa amandla enhlanganisela njengesithuthukisi senkumbulo.
Isici
(1) Ukuhlanzeka okuphezulu: I-PRL-8-53 ingathola imikhiqizo ehlanzekile ngokusebenzisa izinqubo zokukhiqiza zokucwenga. Ukuhlanzeka okuphezulu kusho i-bioavailability engcono kanye nokusabela okungekuhle okumbalwa.
(2) Ukuphepha: Ukuphepha okuphezulu, ukusabela okubi okumbalwa, akukho ukusabela okusobala okusobala.
(3) Ukuzinza: I-PRL-8-53 inokuzinza okuhle futhi ingagcina umsebenzi wayo nomthelela ngaphansi kwezindawo ezihlukene nezimo zokugcina.
Izinhlelo zokusebenza
Njengohlobo olusha lwesithasiselo sokuthuthukisa ingqondo, i-PRL-8-53 ithuthukisa inkumbulo yesikhashana kanye nenkumbulo yokusebenza, kuyilapho ithuthukisa ikhono lokufunda nesivinini sokuthola amakhono, kusiza ukuthuthukisa ukufunda nokusebenza kahle. Ucwaningo lubonisa ukuthi i-PRL-8-53 ingakhuthaza ukukhula nokuvuselelwa kwama-neurons ebuchosheni. I-PRL-8-53 ingakhuphula isivinini lapho ubuchopho bucubungula khona ulwazi, okuvumela abantu ukuba baqedele imisebenzi futhi benze izinqumo ngokushesha. Nakuba kuqhathaniswa namanye ama-nootropic compounds Nokho, ucwaningo ku-PRL-8-53 lulinganiselwe, kodwa ucwaningo olukhona lubonisa amandla alo ekuthuthukiseni inkumbulo namakhono okuqonda.
