I-Nefiracetam powder umkhiqizi we-CAS No.: 77191-36-7 99% ubumsulwa min.okwengeza izithako
Amapharamitha womkhiqizo
| Igama lomkhiqizo | I-Nefiracetam |
| Elinye igama | n-(2,6-dimethylphenyl)-2-oxo-1-pyrrolidineacetamide;NEFIRACETAM; I-2-oxo-1-pyrrolidinylaceticacid, i-2,6-dimethylanilide; dm9384; n-(2,6-dimethylphenyl) -2-oxo-1-pyrrolidineacetamid;DM-9384,(2-(2-Oxopyrrolidin-1-yl)-N-(2,6-dimethylphenyl)-acetamide); I-DMMPA |
| Inombolo ye-CAS. | 77191-36-7 |
| Ifomula yamangqamuzana | I-C14H18N2O2 |
| Isisindo samangqamuzana | 246.3 |
| Ubumsulwa | 99.0% |
| Ukubukeka | Impushana emhlophe |
| Ukupakisha | 25 kg/umgqomo |
| Isicelo | i-nootropic |
Isingeniso somkhiqizo
I-Nefiracetam ingeyeqembu lezidakamizwa ezithuthukisa ukuhlakanipha okungezona emngceleni, ezinezakhiwo zamakhemikhali ezihlukene futhi ezithuthukisa ikhono lokucabanga futhi zivimbele ukulimala kokufunda nenkumbulo ngemiphumela yazo ku-cortex ye-cerebral.Ayinazo izici ze-muscarinic receptor agonists nabaphikisi, futhi ayivimbeli umsebenzi we-Ach.Imiphumela ephikisana nokukhohlwa kanye nenkumbulo yokuthuthukisa inkumbulo yalo muthi ifinyelelwa ngokuthuthukisa ukukhululwa kwe-Ach ku-cerebral cortex.Ama-protein kinases ancike ekamu athuthukisa umsebenzi wesiteshi se-Ca2+, okungase kube nesibopho sokukhishwa kwawo okuthuthukisiwe kwe-Ach.I-Nefiracetam (NEF) iyi-agent ye-pyrrolidone yohlobo lwe-nootropic ene-pharmacologic ehlukahlukene kanye nemiphumela yokuthuthukisa ukuqonda.Ekubanjweni kwe-amygdala-kindled, i-nefiracetam ivimbela kokubili ukuthunjwa kwe-electroencephalographic kanye nokuziphatha.I-NEF ine-spectrum ye-anticonvulsant ehlukile.
Isici
I-Nefiracetam isetshenziselwa ukwelapha izifo ze-cerebrovascular.Ingathuthukisa ikhono lokucabanga futhi ivimbele ukulimala kokufunda nenkumbulo ngomphumela wayo ku-cerebral cortex.Ayinazo izici ze-muscarinic receptor agonist kanye ne-antagonistic agent, futhi ayivimbeli umsebenzi we-acetyl cholinase.Ngakho-ke, imiphumela yayo yokulwa nokukhohlwa kanye nokuthuthukisa inkumbulo kwenzeka ngokuthuthukisa ukukhululwa kwe-acetylcholine ku-cortex ye-cerebral.
Izinhlelo zokusebenza
I-Nefiracetam iwumphumela we-hydrophobic we-piracetam kanye ne-synthetic synthesis yazo zonke izinhlanganisela ze-Racetam i-piracetam.I-Nefiracetam ikhiqizwa ngokuyinhloko yi-Daiichi Sankyo (inkampani yaseJapane eyenza imithi) yokwelapha i-AD.Ngaphezu kwazo zonke izindlela ezishiwo nge-Nefiracetam, ngokuvamile kucatshangwa ukuthi iyinto enesibopho sokutholakala kweziteshi ze-calcium emzimbeni, kanye nokudluliswa okungaqondile kwento ekhombisa injabulo, esebenza njenge-agonist eyingxenye ye- Indawo ebopha i-glycine yesamukeli se-NDMA.
