Umkhiqizi wempuphu we-Beta-Nicotinamide adenine dinucleotide disodium salt (NADH) Inombolo ye-CAS: 606-68-8 95% ubumsulwa obuncane. Izithako zezithako eziningi
Amapharamitha Omkhiqizo
| Igama lomkhiqizo | I-NADH |
| Elinye igama | i-eta-d-ribofuranosyl-3-pyridinecarboxamide,usawoti we-disodium; i-BETA-NICOTINAMIDEADENINEDINUCLEOTIDE,IFOMU EHLISIWEDISODIUMSAWU; i-BETA-NICOTINAMIDE-ADENINEDINUCLEOTIDE,EHLISIWE,2NA; i-BETA-NICOTINAMIDEADENINEDINUCLEOTIDEEDEDUDEDISODIUMSAWU; i-BETA-NICOTINAMIDEADENINEDINUCLEOTIDE,DISODIUMSAWU; i-beta-Nicotinamideadeninedinucleotidedisodiumsawudihydrate; i-eta-d-ribofuranosyl-3-pyridinecarboxamide,usawoti we-disodiumbeta-nicotinamideadeninedinucleotide,usawoti we-disodium,hydratebeta-nicotinamideadeninedinucleotidedisodiumsawudi,i-trihydrate; i-NICOTINAMIDEADENINEDINUCLEOTIDE(EHLISIWE)DISODIUMSAWUDIOLUPHELELE |
| Inombolo ye-CAS | 606-68-8 |
| Ifomula yama-molecule | C21H30N7NaO14P2 |
| Isisindo sama-molecule | 689.44 |
| Ubumsulwa | 95% |
| Ukubukeka | Impuphu emhlophe kuya kophuzi |
| Isicelo | Isengezo Sokudla Izinto Ezingavuthiwe |
Isingeniso somkhiqizo
I-NADH iyi-biomolecule ehilelekile ekusetshenzisweni kwamandla ngaphakathi kweseli. Iyi-coenzyme ebalulekile ekuguquleni ama-molecule okudla njenge-glucose nama-fatty acid abe amandla e-ATP. I-NADH uhlobo oluncishisiwe lwe-NAD+ kanti i-NAD+ uhlobo olu-oxidized. Yakhiwa ngokwamukela ama-electron nama-proton, inqubo ebalulekile ekuphenduleni okuningi kwe-biochemical. I-NADH idlala indima ebalulekile ekusetshenzisweni kwamandla ngokunikeza ama-electron ukukhuthaza ukusabela kwe-redox ngaphakathi kweseli ukukhiqiza amandla e-ATP. Ngaphezu kokuhlanganyela ekusetshenzisweni kwamandla, i-NADH ibandakanyeka nakwezinye izinqubo eziningi ezibalulekile zebhayoloji, njenge-apoptosis, ukulungiswa kwe-DNA, ukuhlukaniswa kwamaseli, njll. Indima ye-NADH kulezi zinqubo ingase ihluke kunendima yayo ekusetshenzisweni kwamandla. I-NADH idlala indima ebalulekile ekusetshenzisweni kwamaseli nemisebenzi yokuphila. Ayiyona nje umdlali obalulekile ekusetshenzisweni kwamandla kuphela, kodwa futhi ihlanganyela kwezinye izinqubo eziningi ezibalulekile zebhayoloji futhi inezinhlelo zokusebenza eziningi.
Isici
(1) Ubumsulwa obuphezulu: I-NADH ingathola imikhiqizo yobumsulwa obuphezulu ngenqubo yokukhiqiza ehlungiwe. Ubumsulwa obuphezulu busho ukutholakala okungcono kwe-bioavailability kanye nokusabela okungekuhle okumbalwa.
(2) Izakhiwo ze-Antioxidant: I-NADH inezakhiwo ezinamandla ze-antioxidant futhi ingavikela amaseli ekulimaleni okubangelwa ukucindezeleka kwe-oxidative kanye nama-free radicals.
(3) Ukuzinza: I-NADH inokuqina okuhle futhi ingagcina umsebenzi wayo kanye nomphumela ngaphansi kwezimo ezahlukene zokugcinwa.
Izicelo
Njengamanje, i-NADH isetshenziswe kabanzi emikhiqizweni yokudla okunempilo, izimonyo nakweminye imikhakha.
Emkhakheni wokudla okunempilo, i-NADH isetshenziswa njengemikhiqizo yezempilo kanye nezithasiselo zokudla okunempilo ukwandisa amazinga amandla omzimba, ukuthuthukisa ukusebenza kwamasosha omzimba, nokukhuthaza impilo iyonke. Ngaphezu kwalokho, i-NADH isetshenziswa kabanzi embonini yezimonyo njengesithako sokulwa nokuguga, esiza ukumelana nomonakalo wama-free radical, ukunciphisa imigqa emincane kanye nemibimbi, nokuthuthukisa ukuqina kwesikhumba kanye nokukhanya. Ngokuqhubeka nokucwaninga ngendlela esebenza ngayo i-NADH kanye nokwanda okuqhubekayo kobubanzi bokusetshenziswa kwayo, amathuba okusetshenziswa kwe-NADH aya ngokuya ethembisa. Esikhathini esizayo, kulindeleke ukuthi i-NADH idlale indima ebaluleke kakhulu kwezokudla okunempilo, izimonyo nakweminye imikhakha.
