Umkhiqizi we-Spermine CAS No.: 71-44-3 99% ubumsulwa min. Izithako ngobuningi
Amapharamitha womkhiqizo
Igama lomkhiqizo | I-spermine |
Elinye igama | i-musculamine;i-neuridine i-gerontine; I-Spermin; I-Gerotine; 4,9-Diaza-1,12-dodecanediamine; N,N'-Bis(3-aminopropyl) -1,4-butanediamine; Diaminopropyltetramethylenediamine; N,N'-Bis(3-aminopropyl)butane-1,4-diamine; 1,4-Butanediamine, N,N'-bis(3-aminopropyl)-; 4,9-Diazadodecamethylenediamine; 1,4-Bis(aminopropyl)butanediamine; 1,4-Bis(aminopropyl) butanediamine; |
Inombolo ye-CAS. | 71-44-3 |
Ifomula yamangqamuzana | C10H26N4 |
Isisindo samangqamuzana | 202.34 |
Ubumsulwa | 98% |
Ukubukeka | Okuqinile (ngaphansi kuka-20 ℃), uketshezi (ngaphezu kuka-30 ℃) |
Ukupakisha | 1kg/isikhwama, 25kg/umgqomo |
Isicelo | I-Dietary Supplement Raw Materials |
Isingeniso somkhiqizo
I-Spermine iyinhlanganisela ye-polyamine eyenzeka ngokwemvelo kuwo wonke amangqamuzana aphilayo, kuhlanganise nezitshalo, izilwane, nama-microorganisms. Kungumkhiqizo ovela ku-metabolism yama-amino acid, amabhlogo wokwakha amaprotheni. I-Spermine idlala izindima ezihlukahlukene emzimbeni futhi inomthelela emisebenzini ehlukahlukene ebalulekile yezinto eziphilayo. Omunye wemisebenzi yawo eyinhloko ukubamba iqhaza ekukhuleni kwamangqamuzana nokwanda. I-Spermine ibalulekile ekugcineni ukuzinza kwezinto zofuzo zeselula, i-DNA ne-RNA, futhi ihileleke ekulawuleni ukubonakaliswa kwezakhi zofuzo. Ukwengeza, i-spermine iboniswe ukuthi inezindawo zokulwa ne-antioxidant ezivikela amangqamuzana emonakalweni we-oxidative futhi zifaka isandla empilweni yonke yamaselula. Ngaphezu kwalokho, i-spermine ihileleke ekulawulweni kwezimpendulo zokuzivikela komzimba futhi ihlobene nokulawulwa kokuvuvukala. Ucwaningo luphinde luveze ukuthi isidoda singase sibambe iqhaza ekusebenzeni kwezinzwa, okunomthelela ezifweni ezinjenge-Alzheimer's kanye nesifo sikaParkinson. Imvelo ehlukahlukene yemisebenzi ye-spermine igqamisa ukubaluleka kwayo ekugcineni impilo nokuphila kahle iyonke.
Isici
(1) Ukuhlanzeka okuphezulu: I-Spermine ingathola imikhiqizo ehlanzekile ngokusebenzisa izinqubo zokukhiqiza zokucwenga. Ukuhlanzeka okuphezulu kusho i-bioavailability engcono kanye nokusabela okungekuhle okumbalwa.
(2) Ukuphepha: Ukuphepha okuphezulu, ukusabela okumbalwa okungekuhle.
(3) Ukuzinza: I-Spermine inokuzinza okuhle futhi ingagcina umsebenzi wayo kanye nomphumela ngaphansi kwezindawo ezahlukene nezimo zokugcina.
Izinhlelo zokusebenza
Eminyakeni yamuva nje, isidoda sidonse ukunakwa kwezicelo ezingase zibe khona. I-Spermine ivimbela ngokubanzi uhlobo lwe-JAK1-mediated I kanye nohlobo lwe-II izimpendulo ze-cytokine zokuzivikela kanye nemiphumela yayo yokuvuvukala. I-Spermine idlala indima yokuzivikela kanye ne-anti-inflammatory ngokubophezela ngokuqondile kuphrotheni ye-JAK1 futhi ivimbele ukubopha kwe-JAK1 kuma-receptors e-cytokine ahlobene, ngaleyo ndlela ivimbele ukwenziwa kusebenze kwezindlela zokudlulisela isignali ezansi nomfula zama-cytokines. Ngaphezu kwalokho, ucwaningo luye lwabonisa ukuthi i-spermine inezindawo zokulwa nokuguga. Izici ezikhuthaza ukunwebeka kwesikhumba futhi zinciphise ukubukeka kwemibimbi. Izakhiwo zayo zokulwa ne-antioxidant ziyenza ibe isithako esibalulekile kumafomula okunakekelwa kwesikhumba ukuze ivikeleke ekucindezelekeni kwemvelo kanye nemisebe ye-UV. Ukwengeza, i-spermine ikhonjiswe ukuthi ithuthukisa ukusebenza kwesithiyo semvelo sesikhumba, isiza ekutholeni amanzi kanye nempilo yesikhumba iyonke. Amandla e-spermine okuthuthukisa isikhumba esisha, esikhazimulayo avuse isithakazelo kanye nesasasa embonini yobuhle. Njengoba umphakathi wesayensi uqhubeka nokuveza ubunkimbinkimbi be-spermine, ucwaningo oluqhubekayo lwembula izinhlelo zalo zokwelapha ezingase zibe khona. Kusukela endimeni yayo ekusebenzeni kwamangqamuzana kuya kumthelela wayo ekunakekelweni kwesikhumba nasekulweni nokuguga, i-spermine inesithembiso sokwenza intuthuko ezindaweni eziningi ezihlobene nempilo.