Umkhiqizi wesidoda Inombolo ye-CAS: 71-44-3 Ubumsulwa obungu-99% ubuncane. Izithako zezithako eziningi
Amapharamitha Omkhiqizo
| Igama lomkhiqizo | Isidoda |
| Elinye igama | imisipha;i-neuridine； i-gerontine； Isidoda； I-Gerotine； 4,9-Diaza-1,12-dodecanediamine； I-N,N'-Bis(3-aminopropyl)-1,4-butanediamine； I-Diaminopropyltetramethylenediamine； I-N,N'-Bis(3-aminopropyl)butane-1,4-diamine； 1,4-Butanediamine, N,N'-bis(3-aminopropyl)-； 4,9-Diazadodecamethylenediamine； 1,4-Bis(aminopropyl)butanediamine； 1,4-Bis(aminopropyl) i-butanediamine； |
| Inombolo ye-CAS | 71-44-3 |
| Ifomula yama-molecule | C10H26N4 |
| Isisindo sama-molecule | 202.34 |
| Ubumsulwa | 98% |
| Ukubukeka | Okuqinile (ngaphansi kuka-20℃), uketshezi (ngaphezu kuka-30℃) |
| Ukupakisha | 1kg/isikhwama, 25kg/ibhareli |
| Isicelo | Izinto Zokusetshenziswa Zokudla Ezingeziwe |
Isingeniso somkhiqizo
I-Spermine iyinhlanganisela ye-polyamine eyenzeka ngokwemvelo kuwo wonke amangqamuzana aphilayo, okuhlanganisa izitshalo, izilwane, kanye nama-microorganism. Ingumkhiqizo ophuma ku-metabolism yama-amino acid, izakhi zamaprotheni. I-Spermine idlala indima ehlukahlukene emzimbeni futhi inegalelo emisebenzini ehlukahlukene ebalulekile yebhayoloji. Omunye wemisebenzi yayo eyinhloko ukubamba iqhaza ekukhuleni nasekukhuleni kwamaseli. I-Spermine ibalulekile ekugcineni ukuzinza kwezinto zofuzo zamaseli, i-DNA ne-RNA, futhi ihilelekile ekulawulweni kokubonakaliswa kwezakhi zofuzo. Ngaphezu kwalokho, i-spermine iboniswe ukuthi inezakhiwo ze-antioxidant ezivikela amangqamuzana ekulimaleni kwe-oxidative futhi inegalelo empilweni yamaseli iyonke. Ngaphezu kwalokho, i-spermine ihilelekile ekulawulweni kwezimpendulo zomzimba futhi ihlobene nokulawulwa kokuvuvukala. Ucwaningo luphinde luphakamise ukuthi i-spermine ingadlala indima emsebenzini wezinzwa, kanye nemiphumela yezifo ezifana nesifo i-Alzheimer's kanye ne-Parkinson's. Uhlobo olunezinhlangothi eziningi lwemisebenzi ye-spermine luqokomisa ukubaluleka kwayo ekugcineni impilo nenhlalakahle iyonke.
Isici
(1) Ukuhlanzeka okuphezulu: Isidoda singathola imikhiqizo ehlanzekile kakhulu ngezinqubo zokukhiqiza zokucwenga. Ukuhlanzeka okuphezulu kusho ukutholakala okungcono kwe-bioavailability kanye nokusabela okuncane okubi.
(2) Ukuphepha: Ukuphepha okuphezulu, ukusabela okungekuhle okumbalwa.
(3) Ukuzinza: Isidoda sinokuqina okuhle futhi singagcina umsebenzi waso kanye nomphumela ngaphansi kwezimo ezahlukene zokugcinwa.
Izicelo
Eminyakeni yamuva nje, i-spermine idonsele ukunaka ngenxa yezindlela zayo zokusebenza ezingaba khona. I-spermine ivimbela kakhulu izimpendulo zomzimba ze-cytokine zohlobo I nohlobo II ezihambisana ne-JAK1 kanye nemiphumela yayo yokuvuvukala. I-spermine idlala indima yokucindezela amasosha omzimba kanye nokulwa nokuvuvukala ngokubopha ngqo kuphrotheni ye-JAK1 nokuvimbela ukubopha kwe-JAK1 kuma-receptor e-cytokine ahlobene, ngaleyo ndlela ivimbele ukusebenza kwezindlela zokudlulisela isignali ze-cytokine ezansi. Ngaphezu kwalokho, izifundo zikhombisile ukuthi i-spermine inezakhiwo zokulwa nokuguga. Izakhiwo ezikhuthaza ukuqina kwesikhumba futhi zinciphise ukubonakala kwemibimbi. Izakhiwo zayo zokulwa ne-antioxidant zenza kube yisithako esibalulekile emafomuleni okunakekelwa kwesikhumba ukuvikela ezingcindezini zemvelo kanye nemisebe ye-UV. Ngaphezu kwalokho, i-spermine iboniswe ukuthi ithuthukisa umsebenzi wemvelo wesithiyo sesikhumba, isiza ekumanzisweni kanye nempilo yesikhumba iyonke. Amandla e-spermine okukhuthaza isikhumba esisha, esikhanyayo avuse isithakazelo kanye nenjabulo embonini yobuhle. Njengoba umphakathi wesayensi uqhubeka nokuxazulula ubunzima be-spermine, ucwaningo oluqhubekayo lwembula izinhlelo zayo zokwelapha ezingaba khona. Kusukela endimeni yayo ekusebenzeni kwamaseli kuya emthonjeni wayo ekunakekelweni kwesikhumba nasekulweni nokuguga, i-spermine inesithembiso sokwenza intuthuko ezindaweni eziningi ezihlobene nempilo.
