Umkhiqizi wempuphu ye-Spermine Tetrahydrochloride (SPT) Inombolo ye-CAS: 306-67-2 Ubumsulwa obungu-98.0% okungenani bezithako ezengeziwe
Amapharamitha Omkhiqizo
| Igama lomkhiqizo | I-N,N'-bis(3-aminopropyl)butane-1,4-diamine,tetrahydrochloride |
| Elinye igama | 1,4-Butanediamine,N,N'-bis(3-aminopropyl)-,tetrahydrochloride;Gerontine tetrahydrochloride; |
| Inombolo ye-CAS | 306-67-2 |
| Ifomula yama-molecule | C10H30Cl4N4 |
| Isisindo sama-molecule | 348.18 |
| Ubumsulwa | 98% |
| Ukubukeka | okuqinile okumhlophe qwa |
| Ukupakisha | 1kg/isikhwama |
| Isicelo | Ukulwa Nokuguga Nokuthuthukiswa Kwekhono Lokuqonda |
Isingeniso Somkhiqizo
I-tetrahydrochloride yesidoda iyinhlanganisela edlala indima ebalulekile ezinqubweni ezahlukahlukene zezinto eziphilayo. Ivela ku-spermine, kodwa ine-ion ezine ze-chloride ezengeziwe. Lokhu kuguqulwa okuncane kungathinta kakhulu izici zayo kanye nokusebenza kwayo. I-tetrahydrochloride yesidoda iyi-polyamine, iqembu lamakhemikhali e-organic anamaqembu amaningi ama-amino. Ama-polyamine abalulekile ekukhuleni nasekusindeni kwamaseli futhi ahilelekile ezinqubweni ezahlukahlukene zamaseli, okuhlanganisa ukuphindaphindwa kwe-DNA, ukuqoshwa, kanye nokuhumusha. Omunye wemisebenzi eyinhloko ye-tetrahydrochloride yesidoda yikhono layo lokuzinzisa i-DNA. Lokhu kwenza lokhu ngokubopha amaqembu e-phosphate ashajeke kabi e-DNA, kunciphise ukushaja kwayo futhi kukhuthaze ukwakheka kwezakhiwo ze-DNA ezizinzile neziqinile. Lokhu kuzinza kubalulekile ekupakishweni nasekuhleleni kwe-DNA okufanele, ekugcineni kuthinte ukubonakaliswa kwezakhi zofuzo kanye nomsebenzi wamaseli. Ngaphezu kwalokho, i-tetrahydrochloride yesidoda ihilelekile ekulawulweni komsebenzi we-enzyme. Ingasebenzisana nama-enzyme futhi iguqule umsebenzi wayo ngokushintsha isakhiwo sayo noma ithinte umsebenzi wayo wokulungisa. Le nqubo ibalulekile ekugcineni i-homeostasis yamaseli nokuqinisekisa ukusebenza kahle kwezindlela ze-enzyme. I-tetrahydrochloride yesidoda nayo idlala indima ekuboniseni amaseli kanye nokuzinza kwe-membrane. Ingasebenzisana nama-phospholipid, ingxenye eyinhloko ye-membrane yeseli. Lokhu kusebenzisana kusiza ukugcina ubuqotho be-membrane yeseli futhi kulawula ukuthuthwa kwama-molecule angena naphumayo eseli.
Isici
(1) Ubumsulwa obuphezulu: I-tetrahydrochloride yesidoda ingathola imikhiqizo yobumsulwa obuphezulu ngezinqubo zokukhiqiza zokucwenga. Ubumsulwa obuphezulu busho ukutholakala okungcono kwe-bioavailability kanye nokusabela okuncane okubi.
(2) Ukuphepha: I-spermine tetrahydrochloride iwumkhiqizo wemvelo futhi kuye kwafakazelwa ukuthi iphephile emzimbeni womuntu.
(3) Ukuzinza: I-tetrahydrochloride yesidoda inokuqina okuhle futhi ingagcina umsebenzi wayo kanye nomphumela ngaphansi kwezimo ezahlukene zokugcinwa.
(4) Kulula ukumunca: I-tetrahydrochloride yesidoda ingamuncwa ngokushesha ngumzimba womuntu futhi isabalaliswe ezicutshini nasezithweni ezahlukene.
Izicelo
I-spermine tetrahydrochloride iyinhlanganisela ebalulekile esiza ezinqubweni ezahlukene zezinto eziphilayo. Njengesengezo sokudla, ngaphezu kwemisebenzi yayo yomzimba, i-spermine tetrahydrochloride iye yacwaningwa ngezinhlelo zayo zokwelapha ezingaba khona. Ngaphezu kwalokho, i-spermine tetrahydrochloride iye yacwaningwa ngezakhiwo zayo zokulwa namagciwane. Kuye kwabonakala ukuthi inemiphumela yokuvimbela ezinhlobonhlobo zezinto eziphilayo ezincane, okuhlanganisa amabhaktheriya, isikhunta, kanye namagciwane. Amandla ayo okuqinisa i-DNA, ukulawula umsebenzi we-enzyme, kanye nokuthonya ukusayinwa kwamaseli kanye nokuqina kwe-membrane kwenza kube ngumdlali obalulekile ekusebenzeni kwamaseli kanye ne-homeostasis.
