I-N-Boc-O-Benzyl-D-serine powder umkhiqizi we-CAS No.:47173-80-8 98% ubumsulwa min. kwabaPhakathi
Amapharamitha womkhiqizo
| Igama lomkhiqizo | I-N-Boc-O-Benzyl-D-serine |
| Elinye igama | I-N-Boc-O-benzyl-D-serine; I-Boc-O-benzyl-D-serine; I-O-Benzyl-N-(tert-butoxycarbonyl)-D-serine; I-Boc-(R) -2-amino-3-benzyloxypropionic acid; I-Boc-D-Ser(Bzl)-OH;Nat.-Boc-O-benzyl-D-serine; I-N-tert-butyloxycarbonyl-O-benzyl-D-serine; I-Nalpha-t-butoxycarbonyl-O-benzyl-D-serine; |
| Inombolo ye-CAS. | 47173-80-8 |
| Ifomula yamangqamuzana | I-C15H21NO5 |
| Isisindo samangqamuzana | 295.33 |
| Ubumsulwa | 98% |
| Ukupakisha | 1kg/isikhwama;25kg/isigubhu |
| Isicelo | Abalamuli |
Isingeniso somkhiqizo
I-N-Boc-O-Benzyl-D-serine iyinhlanganisela esithole ukunakwa okubalulekile emkhakheni we-organic chemistry kanye nocwaningo lwezemithi. Le nhlanganisela, eyaziwa nangokuthi i-Boc-D-serine, iphuma ku-amino acid D-serine futhi isetshenziswa kabanzi ekuhlanganiseni kwemithi ehlukahlukene nama-molecule e-bioactive. I-N-Boc-O-Benzyl-D-serine iyi-crystalline powder emhlophe kuya kokumhlophe encibilika kancane emanzini futhi inyibilika kuzincibilikisi eziphilayo njenge-methanol ne-ethanol. Iphuma ku-D-serine, okuyi-amino acid engeyona i-proteinogenic edlala indima ebalulekile ohlelweni lwezinzwa olumaphakathi njenge-co-agonist ye-N-methyl-D-aspartate (NMDA) receptor. Amaqembu e-N-Boc (tert-butoxycarbonyl) kanye ne-O-Benzyl kunhlanganisela asebenza njengamaqembu avikelayo, okuvumela ukushintshwa okukhethiwe kwe-amino acid ngesikhathi sokuhlanganiswa kwamakhemikhali.I-N-Boc-O-Benzyl-D-serine isetshenziswa ngokuyinhloko njenge-amino acid. Isakhiwo ekuhlanganiseni ama-peptides kanye ne-peptidomimetics. Ama-Peptide amaketanga amafushane ama-amino acid adlala indima ehlukahlukene ezinqubweni zebhayoloji futhi anentshisekelo enkulu ekutholakaleni nasekuthuthukisweni kwezidakamizwa. Ngokuhlanganisa i-N-Boc-O-Benzyl-D-serine ekulandeleni kwe-peptide, osokhemisi bangakwazi ukulungisa izakhiwo nemisebenzi yama-peptide angumphumela, bawenze ithuluzi elibalulekile ekwakhiweni kwama-ejenti emithi anoveli. Ngaphezu kwalokho, i-N-Boc-O-Benzyl-D-serine isetshenziswa ekulungiseleleni ama-intermediate emithi kanye nezithako ezisebenzayo zemithi (ama-API). Ukusebenza kwayo okuguquguqukayo nokuhambisana nokushintshashintsha kwamakhemikhali okuhlukahlukene kuyenza ibe yingxenye efunwa kakhulu ekuhlanganisweni kwama-molecule ayinkimbinkimbi anamandla okwelapha.
Isici
(1) Ukuhlanzeka okuphezulu: I-N-Boc-O-Benzyl-D-serine ingathola imikhiqizo ehlanzekile ngokusebenzisa izinqubo zokukhiqiza zokucwenga. Ukuhlanzeka okuphezulu kusho i-bioavailability engcono kanye nokusabela okungekuhle okumbalwa.
(2) Ukuphepha: Ukuphepha okuphezulu, ukusabela okumbalwa okungekuhle.
(3) Ukuzinza: I-N-Boc-O-Benzyl-D-serine inokusimama okuhle futhi ingagcina umsebenzi wayo nomthelela ngaphansi kwezindawo ezihlukene nezimo zokugcina.
Izinhlelo zokusebenza
Ukufakwa kwe-N-Boc-O-Benzyl-D-serine kuma-molecule ezidakamizwa kukhonjiswe ukuthi kunikeza izakhiwo ezifiselekayo ze-pharmacokinetic kanye ne-pharmacodynamic. I-Peptidomimetics etholakala ku-N-Boc-O-Benzyl-D-serine ibonise ukuzinza okuthuthukisiwe, i-bioavailability, kanye nokucaciswa okuqondisiwe, okubenza babe abantu abathembisayo ekwelapheni izifo ezihlukahlukene, okuhlanganisa umdlavuza, izifo ezithathelwanayo, nokuphazamiseka kwemizwa.Ngaphezu kwalokho, ikhono ukushintsha ngokukhetha ingxenye ye-N-Boc-O-Benzyl-D-serine ivumela ukulungiswa kahle kwamakhandidethi ezidakamizwa, kuthuthukise ukusebenza kahle kwawo kanye namaphrofayili okuphepha.
