Umkhiqizi wempuphu ye-nicotinamide riboside encishisiwe Inombolo ye-CAS:19132-12-8 Ubumsulwa obungu-98% min. wezithako ezengeziwe
Amapharamitha Omkhiqizo
| Igama lomkhiqizo | I-riboside ye-nicotinamide encishisiwe (NRH) |
| Elinye igama | 1-(beta-D-Ribofuranosyl)-1,4-dihydronicotinamide；1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4H-pyridine-3-carboxamide； 1,4-dihydro-1beta-d-ribofuranosyl-3-pyridinecarboxamide； 1-(beta-D-ribofuranosyl)-1,4-dihydropyridine-3-carboxamide； |
| Inombolo ye-CAS | 19132-12-8 |
| Ifomula yama-molecule | C11H16N2O5 |
| Isisindo sama-molecule | 256.26 |
| Ubumsulwa | 98% |
| Ukupakisha | 1kg/isikhwama; 25kg/isigubhu |
| Isicelo | izinto zokusetshenziswa zesengezo sokudla |
Isingeniso somkhiqizo
I-nicotinamide riboside (NRH) encishisiwe iwuhlobo olusha oluncishisiwe lwe-nicotinamide riboside futhi iyisandulela esinamandla se-NAD+, i-coenzyme ehilelekile ezinqubweni ezahlukahlukene zamaseli, okuhlanganisa i-metabolism yamandla kanye nokulungiswa kwe-DNA. Njengoba siguga, amazinga e-NAD+ emzimbeni ayancipha, okuhambisana nezinkinga ezahlukene zempilo ezihlobene nokuguga. Ngokwandisa amazinga e-NAD+, i-NRH ingasiza ekuthuthukiseni ukusebenza kwe-mitochondrial, okubalulekile ekukhiqizweni kwamandla eseli. Lokhu, nakho, kungaholela ekwandeni kwamazinga amandla kanye namandla aphelele. Ngaphezu kwalokho, i-NRH ingasiza ekusekeleni amazinga e-cholesterol anempilo futhi ithuthukise ukusebenza kwenhliziyo nemithambo yegazi. Ucwaningo lubonisa ukuthi i-NRH ingase isekele impilo yobuchopho kanye nokusebenza kwengqondo, okungenzeka ivimbele ukwehla kwengqondo okuhlobene nokuguga. Ngokukhuthaza ukuguga kobuchopho okunempilo kanye nokusekela umsebenzi we-neuronal, i-NR ingaba nomthelela ekugcineni amandla okuqonda njengoba siguga.
Isici
(1) Ubumsulwa obuphezulu: I-riboside ye-nicotinamide encishisiwe ingathola imikhiqizo yobumsulwa obuphezulu ngezinqubo zokukhiqiza zokucwenga. Ubumsulwa obuphezulu busho ukutholakala okungcono kwe-bioavailability kanye nokusabela okungekuhle okumbalwa.
(2) Ukuphepha: Ukuphepha okuphezulu, ukusabela okungekuhle okumbalwa.
(3) Ukuzinza: I-riboside ye-nicotinamide encishisiwe inokuqina okuhle futhi ingagcina umsebenzi wayo kanye nomphumela ngaphansi kwezimo ezahlukene zokugcinwa.
Izicelo
I-riboside ye-nicotinamide encishisiwe ingasetshenziswa njengesengezo emkhakheni wokulwa nokuguga. Ngaphezu kwamandla ayo okulwa nokuguga, i-NRH iye yacwaningwa ngendima yayo ekuthuthukiseni impilo ye-metabolic. Sekukonke, i-riboside ye-nicotinamide encishisiwe inezinhlobo eziningi zezicelo, kusukela ekulweni nokuguga kanye nempilo ye-metabolic. Njengoba ucwaningo kule ndawo luqhubeka nokuthuthuka, i-NRH ingaba isengezo esiwusizo sokukhuthaza impilo nenhlalakahle iyonke.
