I-Palmitoylethanolamide (PEA) umkhiqizi we-powder CAS No.: 544-31-0 99% ubumsulwa min. okwengeza izithako
Amapharamitha womkhiqizo
| Igama lomkhiqizo | I-PEA |
| Elinye igama | N-(2-HYDROXYETHYL)HEXADECANAMIDE; N-HEXADECANOYLETHANOLAMINE; I-PEAPALMIDROL; I-PALMITYLETHANOLAMIDE; I-PALMITOYLETHIncwadi Yekhemikhali i-ANOLAMIDE |
| Inombolo ye-CAS. | 544-31-0 |
| Ifomula yamangqamuzana | I-C18H37NO2 |
| Isisindo samangqamuzana | 299.49 |
| Ubumsulwa | 99.0% |
| Ukubukeka | I-crystalline powder emhlophe |
| Ukupakisha | 25Kg/ isigubhu |
| Isicelo | Izinto zokusetshenziswa zemikhiqizo yokunakekelwa kwezempilo |
Isingeniso somkhiqizo
I-Palmitoylethanolamide iyi-molecule ye-lipid messenger eyatholwa okokuqala ngasekupheleni kwawo-1950. Kungokwesigaba sezinhlanganisela ezibizwa nge-endocannabinoids, okuyizinto zemvelo ezisebenzisana nesistimu ye-endocannabinoid yomzimba. Ngokungafani namanye ama-cannabinoids anjenge-THC atholakala esitshalweni sensangu, i-PEA ayisebenzi ngokwengqondo futhi ayikhiqizi noma yimiphi imiphumela eshintsha ingqondo. Uhlelo lwe-endocannabinoid (ECS) luyinethiwekhi eyinkimbinkimbi yama-receptors nama-endocannabinoids atholakala kuwo wonke umzimba. Idlala indima ebalulekile ekulawuleni izinqubo ezihlukahlukene zomzimba, okuhlanganisa ukubona ubuhlungu, ukuvuvukala, kanye nemizwelo. I-PEA isebenza njenge-endogenous ligand yesamukeli esithile ngaphakathi kwe-ECS ebizwa nge-peroxisome proliferator-activated receptor-α (PPAR-α). Ngokuvula le receptor, i-PEA isebenzisa imiphumela yayo yokulwa nokuvuvukala kanye ne-analgesic. Ucwaningo lubonisa ukuthi i-Palmitoylethanolamide ingasiza ukuphatha ubuhlungu obungapheli, kuhlanganise nobuhlungu be-neuropathic nokuvuvukala. Isebenza ngokunciphisa ukukhululwa kwezinto ezinokuvuvukala nokulawula ukusebenza kwamangqamuzana omzimba athintekayo ekuphenduleni ukuvuvukala. Izivivinyo eziningi zemitholampilo zibonise ukusebenza kahle kwe-PEA ekunciphiseni ubuhlungu obukhulu nokuthuthukisa izinga lokuphila ezigulini ezinezimo ezihlukahlukene zobuhlungu obungapheli.
Isici
(1) Ukuhlanzeka okuphezulu: I-PEA ingathola imikhiqizo ehlanzekile ngokusebenzisa izinqubo zokukhiqiza zokucwenga. Ukuhlanzeka okuphezulu kusho i-bioavailability engcono kanye nokusabela okungekuhle okumbalwa.
(2) Ukuphepha: Ukuphepha okuphezulu, ukusabela okumbalwa okungekuhle.
(3) Ukuzinza: I-PEA inokuzinza okuhle futhi ingagcina umsebenzi wayo nomthelela ngaphansi kwezimo ezihlukene nezimo zokugcina.
Izinhlelo zokusebenza
Isetshenziswa njengesengezo sokudla, i-Palmitoylethanolamide iyi-amide ye-fatty acid eyenzeka ngokwemvelo esebenzisa imiphumela elwa nokuvuvukala, i-analgesic, kanye ne-neuroprotective ngokusebenzisa ukuguqulwa kwesistimu ye-endocannabinoid. Izinzuzo zayo ezingaba khona zokuphatha ubuhlungu obungapheli nezinye izimo zezempilo zikwenza kube inketho ethakazelisayo kubantu abafuna ezinye izindlela zemvelo. Ngaphezu kwalokho, i-PEA iphinde ibe i-organic synthesis ephakathi nendawo yemithi, engasetshenziswa ocwaningweni lwaselabhorethri nezinqubo zokuthuthukiswa kanye nezinqubo zocwaningo lwezidakamizwa zamakhemikhali kanye nentuthuko.
