I-Olivetol (3,5-Dihydroxypentylbenzene) umenzi we-powder CAS No.: 500-66-3 98% ubumsulwa min.okwengeza izithako
Amapharamitha womkhiqizo
| Igama lomkhiqizo | I-Olivetol |
| Elinye igama | 3,5-dihydroxyyamylbenzene; 5-Pentyl-1,3-benzenediol; 5-Pentylresorcinol; I-Pentyl-3,5-dihydroxybenzene |
| Inombolo ye-CAS: | 500-66-3 |
| Ifomula yamangqamuzana | I-C11H16O2 |
| Isisindo samangqamuzana | 180.25 |
| Ubumsulwa | 98.0% |
| Ukubukeka | Impushana ebomvu ensundu |
| Ukupakisha | 1kg/isikhwama 25kg/isigubhu |
| Isicelo | Izinto ezingavuthiwe zemikhiqizo yokunakekelwa kwezempilo |
Isingeniso somkhiqizo
I-Olivetol iyisidakamizwa esibalulekile esimaphakathi.I-Olivetol yaqala ukuthuthukiswa ngokululaza i-lichenic acid (eyaziwa nangokuthi i-D-cerosol acid ne-valerine acid) ekhishwe ezitshalweni ze-lichen.Isetshenziswa kakhulu ekuthuthukisweni kwelabhorethri nokukhiqizwa kwamakhemikhali.I-Olivetol iyinhlanganisela yemvelo ye-polyphenolic etholakala kuma-lichen, noma ekhiqizwa ezinye izinambuzane.I-Olivetol ivimbele ngokuncintisana ama-cannabinoid receptors CB1 kanye ne-CB2, futhi yavimbela umsebenzi we-CYP2C19 ne-CYP2D6, ngamanani we-IC50 we-15.3 μM, 7.21 μM, 2.71 μM, 2.87 μM, ngokulandelana.
Isici
I-Olivine alcohol inezinhlobonhlobo zezinto eziphilayo, ngokumelene nezinhlobonhlobo zezifo zesikhunta kanye nama-bacteria ayasebenza.Eminyakeni yamuva, kutholakale ukuthi ukugxila okuphezulu kwe-3, i-5-dihydroxyalkylbenzene kungaphula i-DNA lapho kukhona i-chloride yethusi kanye ne-oxygen.Ngakho-ke, ingasetshenziswa ukuvimbela nokwelapha ukuntula kwamasosha omzimba womuntu, umdlavuza nezinye izimila ezimbi ezibangelwa i-retrovirus.IHydroxy alkylbenzene ingasetshenziswa futhi ukwenza ama-cannabinoids, ikilasi lezinto ezifanayo ngamakhemikhali ku-cannabis ezihlobene nomsebenzi wokuphila komzimba womuntu.Kunezingaphezu kuka-60 zazo, ezingase zisetshenziselwe ukudambisa izinhlungu, ukuthulisa, ukulwa nokuvuvukala, usizo lokugaya ukudla kanye ne-anti-hypertension.Okuthatha indawo kuleli klasi lezinhlanganisela yi-Olivetol
Izinhlelo zokusebenza
I-Olivetol isetshenziswa njengemolekyuli yesifanekiso ekuhlanganisweni kwama-polymers e-molecularly imprinted (MIP).Iphinde isetshenziswe njenge-inhibitor ye-(S) -phenylalanine 4' -hydroxylase umsebenzi we-CYP2C19 recombinant.I-Olivetol (5-Pentylresorcinol, 5-n-Amylresorcinol), eyaziwa nangokuthi i-olivine alcohol noma i-3, i-5-dihydroxypentylbenzene, iyinhlanganisela yemvelo ye-polyphenolic engusandulela osetshenziswa ekuhlanganiseni kwe-tetrahydrocannabinol futhi ine-antibacterial, antitumor ne-immunoreactive effects.I-Olivetol iyi-inhibitor yokuncintisana yama-cannabinoid receptors CB1 kanye ne-CB2.
