Umkhiqizi wempuphu yePalmitoylethanolamide (PEA) Inombolo ye-CAS: 544-31-0 Ubumsulwa obungu-99% okungenani bezithako ezengeziwe
Amapharamitha Omkhiqizo
| Igama lomkhiqizo | I-PEA |
| Elinye igama | I-N-(2-HYDROXYETHYL)HEXADECANAMIDE; I-N-HEXADECANOYLETHANOLAMINE; I-PEAPALMIDROL; I-PALMITYLETHANOLAMIDE; I-PALMITOYLETHIncwadi yamakhemikhaliI-ANOLAMIDE |
| Inombolo ye-CAS | 544-31-0 |
| Ifomula yama-molecule | C18H37NO2 |
| Isisindo sama-molecule | 299.49 |
| Ubumsulwa | 99.0% |
| Ukubukeka | Impuphu emhlophe ekristalu |
| Ukupakisha | 25Kg/ isigubhu |
| Isicelo | Izinto zokusetshenziswa kwemikhiqizo yokunakekelwa kwempilo |
Isingeniso somkhiqizo
I-Palmitoylethanolamide iyi-molecule ye-lipid messenger eyatholwa okokuqala ngasekupheleni kwawo-1950. Iyingxenye yeqembu lama-compounds abizwa ngokuthi ama-endocannabinoid, okuyizinto zemvelo ezisebenzisana nohlelo lwe-endocannabinoid lomzimba. Ngokungafani nezinye i-cannabinoids ezifana ne-THC ezitholakala esitshalweni se-cannabis, i-PEA ayisebenzi engqondweni futhi ayivezi imiphumela eshintsha ingqondo. Uhlelo lwe-endocannabinoid (ECS) luyinethiwekhi eyinkimbinkimbi yama-receptor nama-endocannabinoids atholakala kuwo wonke umzimba. Idlala indima ebalulekile ekulawuleni izinqubo ezahlukahlukene zomzimba, kufaka phakathi ukuqonda ubuhlungu, ukuvuvukala, kanye nemizwa. I-PEA isebenza njenge-endogenous ligand ye-receptor ethile ngaphakathi kwe-ECS ebizwa ngokuthi i-peroxisome proliferator-activated receptor-α (PPAR-α). Ngokusebenzisa le receptor, i-PEA isebenzisa imiphumela yayo yokulwa nokuvuvukala kanye ne-analgesic. Izifundo zibonisa ukuthi i-Palmitoylethanolamide ingasiza ekuphatheni ubuhlungu obungapheli, kufaka phakathi ubuhlungu be-neuropathic kanye nokuvuvukala. Isebenza ngokunciphisa ukukhishwa kwezinto ezibangela ukuvuvukala kanye nokulawula ukusebenza kwamaseli omzimba ahilelekile empendulweni yokuvuvukala. Izivivinyo eziningi zemitholampilo zibonise ukusebenza kahle kwe-PEA ekunciphiseni ubukhali bobuhlungu kanye nokuthuthukisa ikhwalithi yokuphila ezigulini ezinezimo ezahlukahlukene zobuhlungu obungapheli.
Isici
(1) Ubumsulwa obuphezulu: I-PEA ingathola imikhiqizo ehlanzekile kakhulu ngezinqubo zokukhiqiza zokucwenga. Ubumsulwa obuphezulu busho ukutholakala okungcono kwezinto eziphilayo kanye nokusabela okuncane okubi.
(2) Ukuphepha: Ukuphepha okuphezulu, ukusabela okungekuhle okumbalwa.
(3) Ukuzinza: I-PEA inokuqina okuhle futhi ingagcina umsebenzi wayo kanye nomphumela ngaphansi kwezimo ezahlukene zokugcinwa.
Izicelo
Isetshenziswa njengesengezo sokudla, i-Palmitoylethanolamide iyi-fatty acid amide eyenzeka ngokwemvelo enemiphumela yokulwa nokuvuvukala, ubuhlungu, kanye nokuvikela imizwa ngokushintshashintsha uhlelo lwe-endocannabinoid. Izinzuzo zayo ezingaba khona zokuphatha ubuhlungu obungapheli kanye nezinye izimo zempilo zenza kube inketho ethokozisayo kubantu abafuna ezinye izindlela zemvelo. Ngaphezu kwalokho, i-PEA iphinde ibe yi-organic synthesis intermediate kanye ne-pharmaceutical intermediate, engasetshenziswa ocwaningweni lwelabhorethri kanye nezinqubo zokuthuthukiswa kanye nocwaningo lwemithi yamakhemikhali kanye nezinqubo zokuthuthukiswa.
