I-1-(1-Adamantylcarbonyl) proline (ACA) umkhiqizi we-powder CAS No.: 35084-48-1 98% ubumsulwa min. okwengeza izithako
Ividiyo Yomkhiqizo
Amapharamitha womkhiqizo
| Igama lomkhiqizo | 1-(1-Adamntylcarbonyl) proline |
| Elinye igama | 1-(1-ADAMANTYLCARBONYL)PYRROLIDINE-2-CARBOXYLIC ACID; I-1-(ADAMANTANE-1-CARBONYL)-PYRROLIDINE-2-CARBOXYLIC ACID; 1-(1-Adamantylcarbonyl)proline;L-Proline, 1-(tricyclo[3.3.1.13,7]dec-1-ylcarbonyl)- |
| Inombolo ye-CAS. | 35084-48-1 |
| Ifomula yamangqamuzana | I-C16H23NO3 |
| Isisindo samangqamuzana | 277.36 |
| Ubumsulwa | 98.0% |
| Ukubukeka | Impushana emhlophe |
| Ukupakisha | 1kg/isikhwama 10kg/isigubhu 25kg/isigubhu |
| Isicelo | I-Nootropic |
Isingeniso somkhiqizo
I-1-(1-Adamantylcarbonyl) i-proline iphuma e-phenylalanine, eyaziwa nangokuthi i-adamantylproline noma i-Ad-Pro. Isetshenziswa kakhulu njenge-catalyst noma i-chiral resolution reagent ku-organic synthesis. Ucwaningo luye lwabonisa ukuthi i-proline engu-1-(1-Adamantylcarbonyl) ingakwazi ukuvuselela ukusabela kwe-nucleophilic asymmetric, njengokusabela kwe-aldehydes ne-alkylene azides, ukusabela kwe-aldehydes ne-sulfuryl folate, ukusabela kwe-aldehydes kanye ne-nitro Methane reactions, njll. Ukusabela, le catalyst inomsebenzi wokwengeza onamandla kakhulu kuma-alkylene azides. I-1-(1-Adamntylcarbonyl) i-proline ingase futhi idale ukusabela kwe-asymmetric amination. I-1-(1-Adamntylcarbonyl) iproline ingasetshenziswa futhi njenge-chiral catalyst ukuze ibangele ukudakwa kotshwala okungalingani. Isibonelo, ingasabela otshwaleni nge-aldehydes noma ama-ketone ukuze ikhiqize i-aldol ehambisanayo noma imikhiqizo ye-hydroxyketone. I-1-(1-Adamntylcarbonyl) proline, njengenhlanganisela ye-chiral organic, inomsebenzi omuhle kakhulu we-catalytic.
Isici
(1)1-(1-Adamntylcarbonyl) iproline iyimpushana emhlophe noma emhlophe enokuncibilika okuhle. Inoncibilika kancane emanzini kodwa ivamise ukuba nokuncibilika okuhle kuzincibilikisi zemvelo. Kuyinhlanganisela ezinzile engagcinwa ekamelweni lokushisa isikhathi eside.
(2) I-1-(1-Adamntylcarbonyl) i-proline iyi-molecule ye-chiral enama-enantiomers amabili. Imvelo yayo ye-chiral iyenza isetshenziswe kabanzi ku-chiral synthesis. Ngokuvamile, kufanele kusetshenziswe isomeri ye-chiral eyodwa kuphela ngenxa yokungeniswa kwayo okuhle kwe-chiral.
(3) Ukuhlanzeka okuphezulu: I-1-(1-Adamntylcarbonyl) i-proline ingathola imikhiqizo ehlanzekile ngezinqubo zokukhiqiza zokucwenga. Ukuhlanzeka okuphezulu kusho i-bioavailability engcono kanye nokusabela okungekuhle okumbalwa.
(4) Ukuzinza: I-proline engu-1-(1-Adamntylcarbonyl) inokusimama okuhle futhi ingagcina umsebenzi wayo nomthelela ngaphansi kwezindawo ezihlukene nezimo zokugcina.
Izinhlelo zokusebenza
I-1-(1-Adamantylcarbonyl) i-proline iyinhlanganisela ye-nitrogen equkethe i-nitrogen, impushana emhlophe noma emhlophe, esetshenziswa njengendawo ephakathi kanye nezinye izinhlelo zokusebenza kwezokwelapha. Ngaphezu kwalokho, ngenxa yezakhiwo zayo eziyingqayizivele ze-chiral, isetshenziswa kabanzi ku-chiral organic synthesis, okuhlanganisa ukusabela kwe-asymmetric nucleophilic add, ukusabela kwe-amination, ukusabela kokuphuza utshwala, njll.
