Umkhiqizi wempuphu yeCompound 7P Inombolo ye-CAS: 1890208-58-8 Ubumsulwa obungu-99% obuncane bezithako ezengeziwe
Ividiyo Yomkhiqizo
Amapharamitha Omkhiqizo
| Igama lomkhiqizo | I-Compound 7P |
| Elinye igama | I-Compound7P;2-[(2-methoxyphenyl)[(4-methylphenyl)sulfonyl]amino]-N-(4-methoxy-3-pyridinyl)acetamide; 2-(N-(2-methoxyphenyl)-4-methylphenylsulfonamido)-N-(4-methoxypyridin-3-yl)acetamide |
| Inombolo ye-CAS | 1890208-58-8 |
| Ifomula yama-molecule | C22H23N3O5S |
| Isisindo sama-molecule | 441.51 |
| Ubumsulwa | 99.0% |
| Ukubukeka | Impuphu emhlophe |
| Isicelo | I-Nootropic |
Isingeniso somkhiqizo
I-Compound 7P ibhekisela enkomishini ethile ephilayo equkethe ama-athomu e-carbon ayisikhombisa. Kumakhemikhali e-organic, i-carbon iyinto ebalulekile ngoba ingakha izibopho ezizinzile namanye ama-athomu, kufaka phakathi ama-athomu e-carbon, ukuze kwakheke ama-molecule ayinkimbinkimbi. Lawa ma-molecule angaba nezakhiwo nemisebenzi eyahlukahlukene, okwenza ama-compound asekelwe ku-carbon abe izakhi zokuphila. Kumamodeli ezilwane okulimala kwe-optic nerve, i-compound 7p iboniswe ukuthi ikhuthaza ukukhula kwama-axon e-GAP-43-positive, okuphakamisa ukuthi umsebenzi wokukhula kwe-neurite we-compound 7p in vitro uhumusha ekukhuthazeni ukuvuselelwa kwe-axonal in vivo. I-Compound 7P powder iyimpuphu emhlophe kuya kwemhlophe ekhiqizwa njenge-tandem compound yokuhlonza ama-anti-ant thromboxane receptor antagonist inhibitors. Eqinisweni, i-compound 7p ibonise ukukhetha kwe-prostaglandin I2 synthase (PTGIS, CYP8A1) uma kuqhathaniswa ne-thromboxane synthase (CYP5A1). Impuphu ye-nootropic compound 7P ikhuthaza ukukhula kwama-axon e-Gap-43-positive, ngaleyo ndlela ivuselele ukuvuselelwa kwe-axonal emzimbeni. I-Complex 7p esezingeni eliphezulu yenzelwe ukuthuthukisa ukuhambisana, ukuthuthukisa isimo sengqondo nokusiza ekulweni nokukhathala. Iphinde ivimbele ukubola kobuchopho futhi isize ekulweni nokulimala kobuchopho okubangelwa ukuphuza utshwala.
Isici
(1) Ubumsulwa obuphezulu: I-Compound 7P ingathola imikhiqizo yobumsulwa obuphezulu ngezinqubo zokukhiqiza ezicwengekile. Ubumsulwa obuphezulu busho ukutholakala okungcono kwe-bioavailability kanye nokusabela okuncane okubi.
(2) Ukuphepha: I-Compound 7P ifakazelwe ukuthi iphephile emzimbeni womuntu.
(3) Ukuzinza: I-Compound 7P inokuqina okuhle futhi ingagcina umsebenzi wayo kanye nomphumela ngaphansi kwezimo ezahlukene zokubeka kanye nezimo zokubeka.
Izicelo
I-Compound 7p ithuthukisa ukukhula kwe-neurite kwama-neuron ayisisekelo akhuliswe avela ku-hippocampus, i-cerebral cortex, kanye ne-retina futhi ibangela ukuvuselelwa kwe-optic nerve kumamodeli ezilwane okulimala kwe-optic nerve. Iphinde ithuthukise ukuhambisana, yelapha ukulimala kobuchopho okuhlobene notshwala, futhi ivimbele i-oxidation ezungeze ubuchopho. Iphinde isize ekuthuthukiseni isimo sengqondo futhi ilwe nokukhathala.
