Umkhiqizi wempuphu ye-Nooglutyl Inombolo ye-CAS: 112193-35-8 Ubumsulwa obungu-99.0% okungenani bezithako ezengeziwe
Amapharamitha Omkhiqizo
| Igama lomkhiqizo | I-Nooglutyl |
| Elinye igama | I-Nooglutil; I-N-[(5-Hydroxy-3-pyridinyl)carbonyl]-L-glutamicacid;N-[(5-Hydroxypyridin-3-yl)carbonyl]-L-glutamicacid; ONK-10; I-L-GlutaMicacid, i-N-[(5-hydroxy-3-pyridinyl)carbonyl]-; I-N-(5-hydroxynicotinoyl)-L-glutamicacid |
| Inombolo ye-CAS | 112193-35-8 |
| Ifomula yama-molecule | C11H12N2O6 |
| Isisindo sama-molecule | 268.22 |
| Ubumsulwa | 99.0% |
| Ukubukeka | Impuphu emhlophe noma ecishe ibe mhlophe |
| Isicelo | Isengezo Sokudla Izinto Ezingavuthiwe |
Isingeniso somkhiqizo
I-Nooglutyl, iyinhlanganisela yokwenziwa engowomndeni we-nootropics we-racemate. Yasungulwa eRussia ngawo-1980 futhi kusukela lapho yathandwa kakhulu ngabasebenzisi abafuna ukuthuthukiswa kwengqondo. I-Nooglutyl ibhekwa njengesithuthukisi se-metabolism yengqondo, okusho ukuthi kucatshangwa ukuthi ithuthukisa ukusebenza kwengqondo ngokwandisa ukukhiqizwa kwamandla kanye ne-metabolism ebuchosheni. Kucatshangwa ukuthi ithuthukisa ukwakheka kwenkumbulo nokugcinwa kwayo ngokukhuthaza ukukhululwa kwe-neurotransmitter acetylcholine ebuchosheni. Ngenxa yalokho, abasebenzisi babhekana nokucutshungulwa kolwazi okuthuthukisiwe, ukugxila okuthuthukisiwe, kanye nokukhumbula ngokushesha.
Ngaphezu kwalokho, kucatshangwa ukuthi i-Nooglutyl ikhuthaza ukukhishwa kwe-glutamate, i-neurotransmitter evuselelayo ebalulekile ekuthuthukiseni ukusebenza kwengqondo. Ngokwandisa amazinga e-glutamate, i-Nooglutyl ithuthukisa i-metabolism yamandla obuchopho, ngaleyo ndlela ithuthukise ukuqaphela, ukucaca kwengqondo, kanye nokusebenza kwengqondo okuphelele. Imiphumela evuselelayo ye-Nooglutyl kuma-receptor e-glutamate ingasiza ekuthuthukiseni ukugxila nokugxila. Ngokuguqula uhlelo lwe-glutamate lobuchopho, le nootropic ingasiza abantu ukuba banqobe ukuphazamiseka futhi balondoloze ukunaka okuqhubekayo, ngaleyo ndlela kwandise umkhiqizo kanye nokusebenza emisebenzini eyahlukahlukene.
Isici
(1) Ubumsulwa obuphezulu: I-Nooglutyl ingathola imikhiqizo yobumsulwa obuphezulu ngokukhipha kwemvelo kanye nenqubo yokukhiqiza kahle. Ubumsulwa obuphezulu busho ukutholakala okungcono kwe-bioavailability kanye nokusabela okuncane okubi.
(2) Ukuphepha: I-Nooglutyl iwumkhiqizo wemvelo oye wafakazelwa ukuthi uphephile kubantu. Ngaphakathi kobubanzi bomthamo, ayinabo ubuthi noma imiphumela emibi.
(3) Ukuzinza: I-Nooglutyl inokuqina okuhle futhi ingagcina umsebenzi wayo kanye nomphumela ngaphansi kwezimo ezahlukene zemvelo kanye nokugcina.
(4) Kulula ukumunca: I-Nooglutyl ingamuncwa ngokushesha ngumzimba womuntu, ingene ekujikelezeni kwegazi ngomgudu wamathumbu, bese isatshalaliswa ezicutshini nasezithweni ezahlukene.
Izicelo
I-Nooglutyl iyilungu lomndeni we-racemate futhi ibonise ithemba elikhulu ekuthuthukiseni ukusebenza kwengqondo nokunikeza izinzuzo ze-nootropic. Amandla ayo okukhulisa inkumbulo, amandla engqondo, ukugxilisa ingqondo, nokuvikela ekucindezelekeni kwe-oxidative kwenza kube inketho ethokozisayo kubantu abafuna ukuthuthukisa ukusebenza kwengqondo. Ucwaningo lusikisela ukuthi isakhiwo samakhemikhali esiyingqayizivele se-Nooglutyl singase sivikele izinzwa. Kucatshangwa ukuthi sinciphisa ukucindezeleka kwe-oxidative, sivimbele ukulimala kwamangqamuzana obuchopho okubangelwa ama-free radicals, futhi sisize ekugcinweni nasekuvuselelweni kokuxhumana kwe-neuronal. Le miphumela engaba khona yokuvikela izinzwa yenza i-Nooglutyl ibe inketho ethokozisayo kubantu abakhathazekile ngokuncipha kokuqonda okuhlobene nobudala noma isifo sezinzwa.
