YDL223C (HBT1) umenzi we-powder CAS No.: 489408-02-8 99% ubumsulwa min.okwengeza izithako
Amapharamitha womkhiqizo
| Igama lomkhiqizo | I-HBT1 |
| Elinye igama | YDL223C |
| Inombolo ye-CAS. | 489408-02-8 |
| Ifomula yamangqamuzana | I-C16H17F3N4O2S |
| Isisindo samangqamuzana | 386.40 |
| Ubumsulwa | 99.0% |
| Ukubukeka | Okuqinile okuphuzi okukhanyayo |
| Ukupakisha | 1kg isikhwama ngasinye 25kg isigubhu ngasinye |
| Isicelo | izidakamizwa ze-nootropic |
Isingeniso somkhiqizo
I-HBT1 ibophezela kusizinda esibopha i-ligand se-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPA-R) ngendlela encike ku-glutamate.Lokhu kusho ukuthi i-HBT1 i-molecule engabophezela kuphela kumasayithi athile kuphrotheni ye-AMPA-R uma kukhona i-glutamate, nokuthi lokhu kubophezela kusiza ukulawula umsebenzi wephrotheni.Ama-receptors e-AMPA avezwa kulo lonke uhlelo lwezinzwa olumaphakathi futhi adlala indima ebalulekile ekuxhumaneni kwe-neuronal, ukucubungula izinzwa, nokufunda, inkumbulo, kanye ne-synaptic plasticity.Ama-receptors e-AMPA anegalelo elikhulu ekudluliselweni kwemithambo yegazi okujabulisayo, alamula ngokushesha, nokushesha ukungezwani komzimba kwama-synapses amaningi, futhi abandakanyeka ekuphenduleni kwasekuqaleni kwezifunda ze-synaptic ku-glutamate.Ama-AMPA receptors avame ukuhlanganiswa nama-NMDA receptors kuma-synapses, futhi ndawonye akhuthaza izinqubo ze-synaptic plasticity ezibandakanyeka ekufundeni, inkumbulo, i-excitotoxicity, kanye ne-neuroprotection.
Isici
I-Brain-derived neurotrophic factor (BDNF) iyisici se-neurotrophic esidlala indima ebalulekile ekugcinweni nasekukhuliseni ama-neurons, futhi sinemiphumela enamandla neminingi ekwandeni, ukuhlukaniswa, ukusinda nokufa kwamangqamuzana e-neuronal kanye ne-non-neuronal, Izenzo njengoba i-modulator ye-neurotransmitter futhi inomthelela ku-neuronal plasticity yokufunda nenkumbulo.Ngakho-ke kubalulekile empilweni nasenhlalakahleni yesimiso sezinzwa.Ukwanda kwe-BDNF kungase kube usizo ekwelapheni nasekuvimbeleni izifo eziningi.
Izinhlelo zokusebenza
I-HBT1 iyinoveli yesithuthukisi se-AMPA ene-agonism ephansi uma iqhathaniswa ne-LY451395 ne-OXP1, ingenisa ukukhiqizwa kwe-brain-derived neurotrophic factor (BDNF), futhi ikhombisa umthelela omncane kuma-primary neuro Agitation.I-HBT1 ibophezela kusizinda esibopha i-ligand se-AMPA-R ngendlela encike ku-glutamate.Ngokubambisana, bakhuthaza izinqubo ze-synaptic plasticity ezibandakanyeka ekufundeni, inkumbulo, ukujabula kanye ne-neuroprotection.Ingathuthukisa ikhono lokuqonda kanye nenkumbulo yobuchopho, futhi ithuthukise ikhono lokufunda labantu.
