I-1,4-DihydronicotinaMide Umkhiqizi we-Riboside powder we-CAS No.: 19132-12-8 98% ubumsulwa min. okwengeza izithako
Amapharamitha womkhiqizo
| Igama lomkhiqizo | 1,4-DihydronicotinaMide Riboside |
| Elinye igama | 1,4-DIHYDRONICOTINAMIDE RIBOSIDE1--[(3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,4-dihydropyridine-3-carboxamideI-SCHEMBL188493711-[(3R,4S,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-4H-PYRIDINE-3-CARBOXAMIDE |
| Inombolo ye-CAS. | 19132-12-8 |
| Ifomula yamangqamuzana | I-C11H16N2O5 |
| Isisindo samangqamuzana | 256.26 |
| Ubumsulwa | 98% |
| Ukubukeka | Impushana emhlophe |
| Ukupakisha | 1kg/isikhwama;25kg/isigubhu |
| Isicelo | Isengezo sokudla izinto ezingavuthiwe |
Isingeniso somkhiqizo
I-1,4-dihydronicotinamide riboside, eyaziwa nangokuthi i-NRH.Ifomu elincishisiwe le-NRH liyisandulela se-NAD+ esinamandla esiza ukugcwalisa amazinga ayo kuseli.
Okokuqala nokubaluleke kakhulu, kubalulekile ukuqonda indima ye-NAD + emzimbeni. I-NAD+ iyi-coenzyme ebandakanyeka ezinqubweni eziningi zamaselula, okuhlanganisa amandla e-metabolism, ukulungiswa kwe-DNA, nokubonakaliswa kofuzo. Njengoba sikhula, amazinga ethu e-NAD+ ayehla, okuye kwaba nesandla enqubweni yokuguga kanye nezifo ezihlobene nobudala. Lokhu kuholele entshisekelweni ekhulayo yokuhlonza ama-molecule angakhuphula amazinga e-NAD+ emzimbeni, futhi i-1,4-dihydronicotinamide riboside ingenye ye-molecule enjalo.
I-1,4-dihydronicotinamide riboside iyisandulela se-NAD+ esinamandla, futhi ucwaningo lubonise ukuthi ingakhuphula ngempumelelo amazinga e-NAD+ kumaseli. Lokhu kuye kwaholela ekuqageleni ukuthi i-1,4-dihydronicotinamide riboside supplementation ingaba namandla okwelapha ezimweni eziningi zezempilo, okuhlanganisa ukuphazamiseka kwe-metabolic, izifo ze-neurodeergenerative, kanye nokwehla okuhlobene nokuguga.
Eqinisweni, kunobufakazi bokuthi i-1,4-dihydronicotinamide riboside ingase isebenze nakakhulu kune-molecule yayo yomzali, i-nicotinamide riboside, emazingeni akhulayo e-NAD+. Lokhu kungenxa yokuthi i-1,4-dihydronicotinamide riboside iyisinciphisi esinamandla, okusho ukuthi kungcono ukunikela ngama-electron endleleni ye-NAD+ synthesis. Ngenxa yalokho, inamandla okukhiqiza i-NAD+ yeselula esebenza ngempumelelo.
Ngaphezu kwendima yayo ku-NAD+ biosynthesis, i-1,4-dihydronicotinamide riboside nayo inezindawo zokulwa ne-antioxidant. Ingcindezi ye-oxidative, ewumphumela wokungalingani phakathi kwama-radicals mahhala nama-antioxidants emzimbeni, ibandakanyeka ezifweni eziningi, okubandakanya umdlavuza, isifo senhliziyo nemithambo yegazi, kanye nokuphazamiseka kwe-neurodegenerative. Ngokukhipha ama-radicals mahhala kanye nokunciphisa ukulimala kwe-oxidative, i-1,4-dihydronicotinamide riboside ingase inikeze izinzuzo zezempilo ezengeziwe ezingaphezu kwendima yayo njengesandulela se-NAD+.
Isici
(1) Ukuhlanzeka okuphezulu: I-1,4-dihydronicotinamide riboside ingathola imikhiqizo ehlanzekile ngezinqubo zokukhiqiza ezicwengisisiwe. Ukuhlanzeka okuphezulu kusho i-bioavailability engcono kanye nokusabela okungekuhle okumbalwa.
(2) Ukuphepha: I-1,4-dihydronicotinamide riboside iwumkhiqizo wemvelo ofakazelwe ukuthi uphephile emzimbeni womuntu.
(3) Ukuzinza: I-1,4-dihydronicotinamide riboside inokuzinza okuhle futhi ingagcina umsebenzi wayo nomthelela ngaphansi kwezindawo ezihlukene nezimo zokugcina.
Izinhlelo zokusebenza
I-1,4-Dihydronicotinamide iwuhlobo oluncishisiwe lwe-nicotinamide riboside. Ingaba khona kuwo womabili amafomu ane-oxidized nancishisiwe futhi iyisandulela se-NAD esanda kutholwa (i-nicotinamide adenine dinucleotide), etholakala njengesithasiselo, ne-NRH ibe isandulela esinamandla nesheshayo se-NAD+ kune-NR.
