I-Compound 7P umkhiqizi we-powder CAS No.: 1890208-58-8 99% ubumsulwa min. okwengeza izithako
Ividiyo Yomkhiqizo
Amapharamitha womkhiqizo
| Igama lomkhiqizo | Inhlanganisela 7P |
| Elinye igama | I-Compound7P;2-[(2-methoxyphenyl)[(4-methylphenyl)sulfonyl]amino]-N-(4-methoxy-3-pyridinyl)acetamide; 2-(N-(2-methoxyphenyl)-4-methylphenylsulfonamido)-N-(4-methoxypyridin-3-yl)acetamide |
| Inombolo ye-CAS. | 1890208-58-8 |
| Ifomula yamangqamuzana | I-C22H23N3O5S |
| Isisindo samangqamuzana | 441.51 |
| Ubumsulwa | 99.0% |
| Ukubukeka | Impushana emhlophe |
| Isicelo | I-Nootropic |
Isingeniso somkhiqizo
I-Compound 7P ibhekisela kunhlanganisela ethile yemvelo equkethe ama-athomu ekhabhoni ayisikhombisa. Kumakhemikhali ezinto eziphilayo, ikhabhoni iyisici esibalulekile ngoba ingakha izibopho ezizinzile namanye ama-athomu, kuhlanganise nama-athomu ekhabhoni, ukuze akhe ama-molecule ayinkimbinkimbi. Lawa ma-molecule angaba nezinhlobonhlobo zezakhiwo nemisebenzi, okwenza izinhlanganisela ezisekelwe kukhabhoni zibe yizakhi zokuphila. Ezilwaneni zezilwane zokulimala kwe-optic nerve, i-compound 7p yaboniswa ukuze ikhulise ukukhula kwe-GAP-43-positive axon, ephakamisa ukuthi umsebenzi wokukhula kwe-neurite we-compound 7p in vitro uhumusha ekukhuthazeni ukuvuselelwa kwe-axonal ku-vivo. I-Compound 7P powder iyimpushana emhlophe ukuya emhlophe ekhiqizwa njengenhlanganisela ye-tandem yokuhlonza i-thromboxane receptor antagonist inhibitors esebenza kabili. Eqinisweni, i-compound 7p ibonise ukukhetha kwe-prostaglandin I2 synthase (PTGIS, CYP8A1) ehlobene ne-thromboxane synthase (CYP5A1). I-nootropic compound 7P powder ikhuthaza ukukhula kwe-Gap-43-positive axon, ngaleyo ndlela ivuselele ukuvuselelwa kwe-axonal emzimbeni. I-Complex 7p yekhwalithi ephezulu iklanyelwe ukuthuthukisa ukusebenzisana, ukuthuthukisa isimo sengqondo nokusiza ukulwa nokukhathala. Iphinde ivimbele ukucwiliswa kobuchopho futhi isize ukulwa nokulimala kobuchopho okubangelwa ukuphuza utshwala.
Isici
(1) Ukuhlanzeka okuphezulu: I-Compound 7P ingathola imikhiqizo ehlanzekile ngezinqubo zokukhiqiza ezicwengisisiwe. Ukuhlanzeka okuphezulu kusho i-bioavailability engcono kanye nokusabela okungekuhle okumbalwa.
(2) Ukuphepha: I-Compound 7P ifakazelwe ukuthi iphephile emzimbeni womuntu.
(3) Ukuzinza: I-Compound 7P inokuzinza okuhle futhi ingagcina umsebenzi wayo nomthelela ngaphansi kwezimo ezihlukene nezimo zokugcina.
Izinhlelo zokusebenza
I-Compound 7p ithuthukisa ukuphuma kwe-neurite yama-neuron athuthukisiwe atholakala ku-hippocampus, i-cerebral cortex, ne-retina futhi ikhuthaza ukuvuselelwa kwenzwa ye-optic kumamodeli ezilwane okulimala kwenzwa ye-optic. Iphinde ithuthukise ukusebenzisana, yelaphe ukulimala kobuchopho obuhlobene notshwala, futhi ivimbele i-oxidation ezungeze ubuchopho. Kuyasiza futhi ukuthuthukisa isimo sengqondo nokulwa nokukhathala.
